Temperature control magnetic stirrer capable of being used for dialysis

Abstract

The utility model provides a temperature control magnetic stirrer capable of being used for dialysis, which comprises a pedestal, a heating disc and a stirring mechanism are respectively arranged in an inner cavity of the pedestal, a box body is arranged at the top of the pedestal, a refrigerating mechanism is arranged on the outer side of the box body, a liquid inlet mechanism and a liquid outlet mechanism are respectively arranged at the top of the box body, and a liquid outlet mechanism is arranged at the bottom of the box body. A glass cylinder is fixedly connected to an inner cavity of the box body, the stirring mechanism comprises a motor, the motor is arranged at the bottom of an inner cavity of the pedestal, an output shaft of the motor is fixedly connected with a magnet, a heating coil is arranged at the bottom of the heating disc, and the refrigerating mechanism comprises a semiconductor refrigerating sheet which is embedded and fixed to the outer side of the box body. A cooling fin is tightly attached to one side of the semiconductor chilling plate. The temperature control magnetic stirrer capable of being used for dialysis solves the problem that a traditional magnetic stirrer is not provided with a cooling structure and is inconvenient to use.

Description

Technical Field

[0001] This utility model relates to the field of magnetic stirrer technology, and in particular to a temperature-controlled magnetic stirrer that can be used for dialysis. Background Technology

[0002] Dialysis is a physical process that separates substances of different molecular weights using a semi-permeable membrane. Its principle is based on diffusion pressure, which drives smaller solute molecules to move from a region of high concentration to a region of low concentration, while larger molecules are retained on one side of the membrane. Dialysis typically requires overnight treatment at low temperatures, primarily to slow down molecular motion during dialysis, thereby prolonging the dialysis time, improving the removal efficiency of smaller molecules, and minimizing the impact on the activity of biological macromolecules, thus maintaining their stability. Low temperature also helps prevent protein denaturation or loss of enzyme activity that may occur during dialysis.

[0003] A magnetic stirrer is a laboratory instrument used for mixing liquids, primarily for stirring or simultaneously heating and stirring low-viscosity liquids or solid-liquid mixtures. Its basic principle is based on the principle of magnetic repulsion and attraction between like and unlike magnetic fields. The magnetic field drives a magnetic stir bar placed in a container to rotate in a circular motion, thus achieving the purpose of stirring the liquid. Because no human intervention is required, magnetic stirrers are widely used in reaction processes that require continuous stirring.

[0004] When dialysis solution is refrigerated, many samples, such as proteins and polyphenols, often precipitate, which can contaminate the dialysis solution, affecting the purity of the sample and the accuracy of subsequent experiments. However, it is inconvenient to place a magnetic stirrer during overnight dialysis at low temperature to reduce precipitation reactions, and traditional magnetic stirrers do not have a cooling structure. Therefore, there is an urgent need for a temperature-controlled magnetic stirrer that can be used for dialysis. Utility Model Content

[0005] To solve the above-mentioned technical problems, this utility model provides a temperature-controlled magnetic stirrer that can be used for dialysis.

[0006] The present invention provides a temperature-controlled magnetic stirrer for dialysis, comprising a base, wherein a heating plate and a stirring mechanism are respectively arranged in the inner cavity of the base, a box is arranged on the top of the base, a cooling mechanism is arranged on the outer side of the box, a liquid inlet mechanism and a liquid outlet mechanism are respectively arranged on the top of the box, and a glass cylinder is fixedly connected to the inner cavity of the box.

[0007] As a temperature-controlled magnetic stirrer for dialysis provided by this utility model, preferably, the stirring mechanism includes a motor, the motor is installed at the bottom of the inner cavity of the base, the output shaft of the motor is fixedly connected to a magnet, and a heating coil is provided at the bottom of the heating plate.

[0008] As a temperature-controlled magnetic stirrer for dialysis provided by this utility model, preferably, the refrigeration mechanism includes a semiconductor refrigeration chip, which is embedded and fixed on the outside of the housing. A heat sink is tightly attached to one side of the semiconductor refrigeration chip, a heat sink fin is provided on one side of the heat sink, and a cooling fan is installed on one side of the heat sink fin.

[0009] As a temperature-controlled magnetic stirrer for dialysis provided by this utility model, preferably, the refrigeration mechanism further includes a cooling block, and a cooling guide hoop is fixedly connected to one side of the cooling block.

[0010] As a temperature-controlled magnetic stirrer for dialysis provided by this utility model, preferably, the liquid inlet mechanism includes a liquid inlet pump, which is installed on the top of the housing, the inlet of the liquid inlet pump is connected to an inlet pipe, and the outlet of the liquid inlet pump is connected to a delivery pipe.

[0011] As a temperature-controlled magnetic stirrer for dialysis provided by this utility model, preferably, the drainage mechanism includes a drainage pump, which is installed on the top of the housing, with the inlet of the drainage pump connected to a drainage pipe and the outlet of the drainage pump connected to an outlet pipe.

[0012] As a temperature-controlled magnetic stirrer for dialysis provided by this utility model, preferably, the housing includes an outer shell, and the interior of the outer shell is provided with a cavity filled with polyurethane foam.

[0013] Compared with the prior art, the beneficial effects of this utility model are:

[0014] This temperature-controlled magnetic stirrer for dialysis uses a motor to drive a magnet, which in turn drives a stir bar inside the dialysis bag for stirring. A semiconductor cooling chip cools the chamber and glass tube. During dialysis, an ultrapure water pump drains the glass tube, and a fresh ultrapure water pump fills it in, facilitating water exchange. When dialysis is not needed, the chamber is removed, the sample solution is placed in a beaker, a stir bar is added, and the beaker is placed on a heating plate. The temperature is adjusted using a temperature controller connected to the heating coil on the base, and the motor drives the magnet to rotate, achieving traditional heating and stirring. This solves the problem that traditional magnetic stirrers lack cooling structures and are inconvenient to use. Attached Figure Description

[0015] Figure 1 A schematic diagram of a preferred embodiment of the temperature-controlled magnetic stirrer for dialysis provided by this utility model;

[0016] Figure 2 This is a cross-sectional view of the box body of this utility model;

[0017] Figure 3 This is a top view of the heating plate of this utility model.

[0018] The following are the labeling elements in the diagram: 1. Base; 2. Heating plate; 3. Stirring mechanism; 301. Motor; 302. Magnet; 303. Heating coil; 4. Box body; 401. Outer shell; 402. Polyurethane foam; 5. Refrigeration mechanism; 501. Semiconductor cooling chip; 502. Heat sink; 503. Heat dissipation fins; 504. Cooling fan; 505. Cooling block; 506. Cooling clamp; 6. Liquid inlet mechanism; 601. Liquid inlet pump; 602. Liquid inlet pipe; 603. Delivery pipe; 7. Liquid outlet mechanism; 701. Liquid outlet pump; 702. Liquid outlet pipe; 703. Glass cylinder. Detailed Implementation

[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0020] Please refer to the following: Figure 1 , Figure 2 and Figure 3 ,in Figure 1 A schematic diagram of a preferred embodiment of the temperature-controlled magnetic stirrer for dialysis provided by this utility model; Figure 2 This is a cross-sectional view of the box body of this utility model; Figure 3 This is a top view of the heating plate of this utility model. A temperature-controlled magnetic stirrer for dialysis includes a base 1, a heating plate 2 and a stirring mechanism 3 respectively arranged in the inner cavity of the base 1, a box 4 arranged on the top of the base 1, a cooling mechanism 5 arranged on the outer side of the box 4, a liquid inlet mechanism 6 and a liquid outlet mechanism 7 respectively arranged on the top of the box 4, and a glass cylinder 8 fixedly connected to the inner cavity of the box 4.

[0021] In this embodiment: the heating plate 2 is mainly made of aluminum alloy and can hold beakers; the glass tube 8 is made of quartz glass and can be used for dialysis reactions.

[0022] As a technical optimization of this utility model, the stirring mechanism 3 includes a motor 301, which is installed at the bottom of the inner cavity of the base 1. The output shaft of the motor 301 is fixedly connected to a magnet 302, and a heating coil 303 is provided at the bottom of the heating plate 2.

[0023] In this embodiment: a motor speed controller is installed on one side of the base 1. The motor speed controller is electrically connected to the motor 301 through a wire. The motor speed controller is used to adjust the speed of the motor 301, thereby controlling the rotation speed of the stirring rotor to adapt to different stirring requirements. The heating coil 303 is fixed to the bottom of the heating plate 2. The motor 301 is also located at the bottom of the heating plate 2, and the magnet 302 is located between the top of the motor 301 and the bottom of the heating plate 2.

[0024] As a technical optimization of this utility model, the cooling mechanism 5 includes a semiconductor cooling chip 501, which is embedded and fixed on the outside of the housing 4. A heat sink 502 is tightly attached to one side of the semiconductor cooling chip 501, a heat sink 503 is provided on one side of the heat sink 502, and a cooling fan 504 is installed on one side of the heat sink 503.

[0025] The refrigeration mechanism 5 also includes a cooling block 505, and a cooling clamp 506 is fixedly connected to one side of the cooling block 505.

[0026] In this embodiment: Two temperature controllers are installed on one side of the base 1. One temperature controller is electrically connected to the thermoelectric cooler 501 via a wire, and the other temperature controller is electrically connected to the heating coil 303 via a wire. Two temperature sensors are installed on the outside of the glass cylinder 8. The detection ends of the two temperature sensors are located inside the glass cylinder 8. The two temperature sensors are electrically connected to the two temperature controllers via wires. The two temperature sensors and the two temperature controllers form two sets of detection units, which are used to detect the high temperature and low temperature inside the glass cylinder 8, respectively. The heat sink 502 is located at the hot end of the thermoelectric cooler 501, the cooling block 505 is located at the cold end of the thermoelectric cooler 501, and the inner side of the cooling band 506 is in contact with the outer side of the glass cylinder 8. By working with the thermoelectric cooler 501, the temperature inside the chamber 4 and at the glass cylinder 8 can be reduced, thereby achieving the low temperature function required during dialysis. The temperature controller connected to the thermoelectric cooler 501 can be used to control the cooling temperature of the thermoelectric cooler 501.

[0027] As a technical optimization of this utility model, the liquid inlet mechanism 6 includes a liquid inlet pump 601, which is installed on the top of the housing 4. The inlet of the liquid inlet pump 601 is connected to the liquid inlet pipe 602, and the outlet of the liquid inlet pump 601 is connected to the delivery pipe 603.

[0028] The drainage mechanism 7 includes a drainage pump 701, which is installed on the top of the housing 4. The inlet of the drainage pump 701 is connected to a drainage pipe 702, and the outlet of the drainage pump 701 is connected to an outlet pipe 703.

[0029] In this embodiment, the ends of the delivery pipe 603 and the drain pipe 702 extend downward along the inner wall of the glass cylinder 8, but do not contact the bottom of the inner cavity of the glass cylinder 8. One end of the inlet pipe 602 is connected to the external water supply pipe, and one end of the outlet pipe 703 is connected to the external drainage pipe. Then, the external water can be delivered to the inside of the glass cylinder 8 and the water inside the glass cylinder 8 can be discharged through the inlet pump 601 and the drain pump 701 at the top, so as to achieve the purpose of easy water replacement and reduce manual operation.

[0030] As a technical optimization of this utility model, the box 4 includes an outer shell 401, and the interior of the outer shell 401 is provided with a cavity, which is filled with polyurethane foam 402.

[0031] In this embodiment, filling the interior of the outer shell 401 with polyurethane foam 402 can achieve a good heat insulation effect.

[0032] The working principle of the temperature-controlled magnetic stirrer for dialysis provided by this utility model is as follows:

[0033] When using this device, place the housing 4 on top of the base 1, ensuring the bottom of the housing 4 is flush with the top of the base 1. Place the sample solution into a dialysis bag containing a stir bar. After venting and sealing, place the bag into a glass cylinder 8. The top of the glass cylinder 8 can be covered with aluminum foil. Ultrapure water is supplied to the glass cylinder 8 via the inlet pump 601. The motor 301 drives the magnet 302 to rotate, thereby driving the stir bar inside the dialysis bag to rotate, performing stirring. The semiconductor cooling chip 501 can regulate the temperature and humidity of the solution. Cooling is performed inside the chamber 4 and glass cylinder 8. During the dialysis period, the ultrapure water in the glass cylinder 8 can be drained by the drain pump 701 and new ultrapure water can be injected by the inlet pump 601 to achieve water replacement. When dialysis is not required, simply remove the chamber 4, put the sample solution into a beaker, add a stir bar to the beaker and place it on the heating plate 2, adjust the temperature through the temperature controller connected to the heating coil 303 on the base 1, and drive the magnet 302 to rotate through the motor 301 to achieve traditional heating and stirring.

[0034] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the content of this utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.

Claims

1. A temperature-controlled magnetic stirrer for dialysis, characterized in that, The device includes a base (1), the inner cavity of which is provided with a heating plate (2) and a stirring mechanism (3), the top of which is provided with a box (4), the outer side of which is provided with a refrigeration mechanism (5), the top of which is provided with a liquid inlet mechanism (6) and a liquid outlet mechanism (7), and the inner cavity of which is fixedly connected with a glass cylinder (8).

2. The temperature-controlled magnetic stirrer for dialysis according to claim 1, characterized in that, The stirring mechanism (3) includes a motor (301), which is installed at the bottom of the inner cavity of the base (1). The output shaft of the motor (301) is fixedly connected to a magnet (302), and a heating coil (303) is provided at the bottom of the heating plate (2).

3. The temperature-controlled magnetic stirrer for dialysis according to claim 1, characterized in that, The cooling mechanism (5) includes a semiconductor cooling chip (501), which is embedded and fixed on the outside of the housing (4). A heat sink (502) is tightly attached to one side of the semiconductor cooling chip (501), and a heat sink fin (503) is provided on one side of the heat sink (502). A cooling fan (504) is installed on one side of the heat sink fin (503).

4. The temperature-controlled magnetic stirrer for dialysis according to claim 3, characterized in that, The refrigeration mechanism (5) also includes a cooling block (505), and a cooling clamp (506) is fixedly connected to one side of the cooling block (505).

5. The temperature-controlled magnetic stirrer for dialysis according to claim 1, characterized in that, The liquid inlet mechanism (6) includes a liquid inlet pump (601), which is installed on the top of the housing (4). The inlet of the liquid inlet pump (601) is connected to an inlet pipe (602), and the outlet of the liquid inlet pump (601) is connected to a delivery pipe (603).

6. The temperature-controlled magnetic stirrer for dialysis according to claim 1, characterized in that, The drainage mechanism (7) includes a drainage pump (701), which is installed on the top of the housing (4). The inlet of the drainage pump (701) is connected to a drainage pipe (702), and the outlet of the drainage pump (701) is connected to an outlet pipe (703).

7. The temperature-controlled magnetic stirrer for dialysis according to claim 1, characterized in that, The housing (4) includes an outer shell (401), and the interior of the outer shell (401) is provided with a cavity, which is filled with polyurethane foam (402).

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