Cell culture fluid infusion device

Abstract

The utility model discloses a cell culture fluid infusion device which comprises a fluid infusion frame, the fluid infusion frame comprises a bottom plate, a supporting arm and a supporting plate, the supporting plate is located above the bottom plate, one side of the supporting plate is fixedly connected with the upper end of the supporting arm, the lower end of the supporting arm is fixedly connected with the bottom plate, and the supporting plate is provided with a positioning hole used for installing an injector. The supporting arm is connected with an injector fixing clamp located below the positioning hole. According to the utility model, the injector required by liquid infusion can be fixed, so that the liquid infusion is more stable, the injector cannot shake due to the movement of a liquid infusion bag, the occurrence of liquid scattering and leakage is avoided, the use of an electric pipettor is reduced, and the risk of pollution is reduced; meanwhile, the height of the liquid supplementing frame can be adjusted, operation of different people is facilitated, and the operation burden of operators is reduced.

Description

Technical Field

[0001] This utility model relates to the field of cell culture technology, and in particular to a cell culture fluid replenishment device. Background Technology

[0002] When large-scale in vitro expansion and culture of immune cells such as CIK cells and NK cells, a large amount of culture medium needs to be added to meet clinical requirements. At the beginning of cell culture, the fluid replenishment volume is low, and commercially available instruments for assisting with cell replenishment, such as electric pipettes, can be used directly. However, when the fluid replenishment volume requirement is large in the later stages of cell culture, frequent use of pipettes not only increases the risk of contamination but also increases the workload. Currently, cell replenishment stands are available on the market; however, these stands cannot stably hold the 50ml syringe required for replenishment, leading to leakage and spillage. Furthermore, the height of the stands is not adjustable, making them unsuitable for different operators.

[0003] Therefore, improvements are needed to the existing fluid replenishment rack structure. Utility Model Content

[0004] The purpose of this invention is to provide a cell culture rehydration device that can not only fix the syringe needed for rehydration, but also adjust the height of the rehydration rack, making it easy for different people to operate, reducing the operator's workload, and effectively solving the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A cell culture fluid replenishment device includes a fluid replenishment rack, which includes a base plate, a support arm, and a support plate. The support plate is located above the base plate. One side of the support plate is fixedly connected to the upper end of the support arm, and the lower end of the support arm is fixedly connected to the base plate. The support plate has a positioning hole for mounting a syringe, and the support arm is connected to a syringe fixing clip located below the positioning hole.

[0007] Furthermore, the syringe clamp includes a symmetrically distributed first clamping member and a second clamping member, with a first screw and nut assembly and a second screw and nut assembly connected between the first clamping member and the second clamping member. Both the first clamping member and the second clamping member have a first C-shaped sleeve for connecting to the support arm and a second C-shaped sleeve for connecting to the syringe. The first screw and nut assembly and the second screw and nut assembly are respectively located at both ends of the first C-shaped sleeve, and the first screw and nut assembly is distributed between the first C-shaped sleeve and the second C-shaped sleeve.

[0008] Furthermore, the inner wall of the second C-shaped jacket is provided with several protruding teeth.

[0009] Furthermore, the cross-sectional shape of the protruding tooth is triangular.

[0010] Furthermore, the two second C-shaped sleeves are located directly below the positioning hole.

[0011] Furthermore, the positioning hole is a circular through hole.

[0012] Furthermore, both the support plate and the base plate are rectangular plates.

[0013] Furthermore, the support arm includes a telescopically adjustable support rod and a support tube. The lower end of the support rod is inserted into the upper end of the support tube. The support tube has a threaded hole in its wall, and a fastener for locking the support rod is installed in the threaded hole.

[0014] Furthermore, the support rod is a cylindrical rod, and the support tube is a cylindrical hollow tube.

[0015] Furthermore, the fastener is a bolt.

[0016] Compared with the prior art, the present invention provides a cell culture fluid replenishment device, which has the following beneficial effects:

[0017] This invention not only secures the syringe needed for fluid refilling, making the process more stable and preventing the syringe from shaking due to movement of the refill bag, thus avoiding spillage and leakage, but also reduces the use of electric pipettes and the risk of contamination. Furthermore, the height of the refill stand can be adjusted to facilitate operation by different people, reducing the workload of operators. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0020] Figure 2 This is a schematic diagram of the syringe holder structure;

[0021] Figure 3 This is a schematic diagram illustrating the use of this utility model.

[0022] Reference numerals: 10, IV rack; 1, base plate; 2, support arm; 21, support rod; 22, support tube; 23, fastener; 3, support plate; 31, positioning hole; 4, syringe clamp; 41, first clamping member; 42, second clamping member; 43, first screw and nut assembly; 44, second screw and nut assembly; 45, first C-type sleeve; 46, second C-type sleeve; 47, protruding tooth; 20, syringe. Detailed Implementation

[0023] The technical solution of this utility model will be clearly and completely described below through detailed embodiments and in conjunction with the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. Based on the embodiments of this utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of this utility model.

[0024] Please refer to Figures 1-3 This embodiment provides a cell culture rehydration device, including a rehydration rack 10. The rehydration rack 10 includes a base plate 1, a support arm 2, and a support plate 3. The support plate 3 is located above the base plate 1. One side of the support plate 3 is fixedly connected to the upper end of the support arm 2, and the lower end of the support arm 2 is fixedly connected to the base plate 1. The support plate 3 has a positioning hole 31 for installing a syringe 20. The support arm 2 is connected to a syringe clamp 4 located below the positioning hole 31. The syringe can be inserted and positioned through the positioning hole on the support plate, while the syringe clamp located below can hold and fix the lower part of the syringe, making the rehydration more stable and preventing the syringe from shaking due to the movement of the rehydration bag, thus avoiding spillage and leakage. It also reduces the use of electric pipettes and reduces the risk of contamination.

[0025] In some specific implementation methods, such as Figure 2As shown, the syringe clamp 4 includes symmetrically distributed first clamping members 41 and second clamping members 42. A first screw and nut assembly 43 and a second screw and nut assembly 44 are connected between the first clamping member 41 and the second clamping member 42. Both the first clamping member 41 and the second clamping member 42 have a first C-shaped sleeve 45 for connecting to the support arm 2 and a second C-shaped sleeve 46 for connecting to the syringe 20. The first screw and nut assembly 43 and the second screw and nut assembly 44 are located at both ends of the first C-shaped sleeve 45, and the first screw and nut assembly 44 is distributed between the first C-shaped sleeve 45 and the second C-shaped sleeve 46. Thus, with the first screw and nut assembly and the second screw and nut assembly locked together, the two first C-shaped sleeves can tightly clamp the support arm, and the two second C-shaped sleeves can tightly clamp the lower middle part of the syringe. When the first screw nut assembly is loosened, the two second C-shaped sleeves will release the syringe, making it easier to remove the syringe; when the second screw nut assembly is loosened, the two first C-shaped sleeves will release the support arm, making it easier to move the syringe retainer up and down to adjust its height.

[0026] As an improved implementation method, refer to Figure 2 The inner wall of the second C-shaped clip 46 is provided with several protruding teeth 47, which makes it easier for the second C-shaped clip to clamp and fix the syringe more firmly.

[0027] In some specific implementations, as examples, refer to Figure 2 The cross-sectional shape of the protruding tooth portion 47 is triangular.

[0028] In some specific implementation methods, refer to Figure 1 and Figure 3 The two second C-shaped sleeves 46 are located directly below the positioning hole 31. This allows the syringe to be positioned vertically for liquid replenishment.

[0029] In some specific implementations, as examples, such as Figure 1 As shown, the positioning hole 31 is a circular through hole.

[0030] In some specific implementations, as an example, Figure 1 As shown, both the support plate 3 and the base plate 1 are rectangular plates, which can provide relatively stable support and liquid replenishment.

[0031] As an improved implementation, the support arm is height-adjustable to allow for adjustment of the IV stand's height. See the attached document for details. Figure 1 and Figure 3The support arm 2 includes a telescopically adjustable support rod 21 and a support tube 22. The lower end of the support rod 21 is inserted into the upper end of the support tube 22. The support tube 22 has a threaded hole in its wall, and a fastener 23 for locking the support rod 21 is installed in the threaded hole. Thus, the support rod and the support plate form the upper arm of the IV rack, and the support tube and the base plate form the lower arm. The support rod can move up and down along the support tube and is locked in place by the fastener, thereby adjusting the height of the IV rack, facilitating operation by different people and reducing the operator's workload.

[0032] In some specific implementations, as examples, such as Figure 1 As shown, the support rod 21 is a cylindrical rod, and the support tube 22 is a cylindrical hollow tube.

[0033] In some specific embodiments, for example, the fastener 23 is a bolt.

[0034] In some specific embodiments, for example, the diameter of the positioning hole 31 is adapted to fit the outer wall of a 50ml syringe. Of course, in other embodiments, the diameter of the positioning hole can be adjusted according to the size of the syringe used.

[0035] The above embodiments are merely illustrative of the concept and technical solution of this utility model, and are not intended to limit this utility model. Any person skilled in the art can modify or alter the above embodiments without departing from the spirit and scope of this utility model. Therefore, all equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in this utility model should still be covered by the claims of this utility model.

[0036] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A cell culture rehydration device, comprising a rehydration rack, characterized in that, The fluid replenishment frame includes a base plate, a support arm, and a support plate. The support plate is located above the base plate. One side of the support plate is fixedly connected to the upper end of the support arm, and the lower end of the support arm is fixedly connected to the base plate. The support plate has a positioning hole for installing a syringe, and the support arm is connected to a syringe fixing clip located below the positioning hole.

2. The cell culture fluid replenishment device according to claim 1, characterized in that, The syringe clamp includes a symmetrically distributed first clamping member and a second clamping member. A first screw and nut assembly and a second screw and nut assembly are connected between the first clamping member and the second clamping member. Both the first clamping member and the second clamping member have a first C-shaped sleeve for connecting to a support arm and a second C-shaped sleeve for connecting to a syringe. The first screw and nut assembly and the second screw and nut assembly are respectively located at both ends of the first C-shaped sleeve, and the first screw and nut assembly is distributed between the first C-shaped sleeve and the second C-shaped sleeve.

3. The cell culture fluid replenishment device according to claim 2, characterized in that, The inner wall of the second C-type jacket is provided with several protruding teeth.

4. The cell culture fluid replenishment device according to claim 3, characterized in that, The cross-sectional shape of the protruding tooth is triangular.

5. The cell culture fluid replenishment device according to claim 2, characterized in that, The two second C-type sleeves are located directly below the positioning hole.

6. The cell culture fluid replenishment device according to claim 1, characterized in that, The positioning hole is a circular through hole.

7. The cell culture fluid replenishment device according to claim 1, characterized in that, Both the support plate and the base plate are rectangular plates.

8. The cell culture rehydration device according to any one of claims 1 to 7, characterized in that, The support arm includes a telescopically adjustable support rod and a support tube. The lower end of the support rod is inserted into the upper end of the support tube. The support tube has a threaded hole in its wall, and a fastener for locking the support rod is installed in the threaded hole.

9. The cell culture fluid replenishment device according to claim 8, characterized in that, The support rod is a cylindrical rod, and the support tube is a cylindrical hollow tube.

10. The cell culture fluid replenishment device according to claim 8, characterized in that, The fastener is a bolt.

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