Microorganism culture device for biological product research

Abstract

The utility model discloses a microorganism culture device for biological product research, a top moving beam is fixedly installed at the middle end of the top of the inner side of a culture box, a driving screw rod is embedded and rotatably connected to the inner side of the top moving beam, one end of the driving screw rod is fixedly connected with an output shaft of a motor, and the other end of the driving screw rod is fixedly connected with an output shaft of the motor. The liquid distribution box and the liquid storage box can be conveniently driven to stably move through the driving screw rod, the motor and the sliding block, so that when the liquid distribution box and the liquid storage box are used for supplementary culture of a culture vessel, the liquid distribution box and the liquid storage box are convenient to move, and the liquid distribution box and the liquid storage box are convenient to move. According to the device, a culture solution can be uniformly supplemented into a culture vessel through a drip irrigation head connected to the bottom of the liquid separation box, and the culture solution can be further uniformly supplemented from one side of the culture vessel to the other side along with the stable movement of the liquid separation box, so that the uniformity of the action of the culture solution on microorganisms in the culture vessel is ensured, and the quality of microorganisms is improved. The phenomenon of inconsistent microbial development conditions is avoided.

Description

Technical Field

[0001] This utility model relates to the field of microbial culture technology, specifically to a microbial culture device for biological product research. Background Technology

[0002] Biological products are made from microorganisms, cells, animal or human tissues and body fluids using traditional or modern biotechnology. They are used for the prevention, treatment and diagnosis of human diseases. Human biological products include: bacterial vaccines, viral vaccines, antitoxins and antisera, enzymes and in vivo and in vitro diagnostic products, as well as other bioactive agents such as toxins, antigens, allergens, monoclonal antibodies, antigen-antibody complexes and immunomodulatory and probiotic agents. In the laboratory, culture devices are usually used to culture microorganisms in order to study the properties of microorganisms.

[0003] However, current culture devices cannot guarantee the uniformity of culture medium addition when culturing microorganisms. This affects the development of microorganisms in different locations within the culture vessel, resulting in inconsistent development due to varying conditions of the culture medium, which impacts subsequent experimental research. Utility Model Content

[0004] This invention provides a microbial culture device for biological product research, which can effectively solve the problem mentioned in the background art that current culture devices cannot guarantee the uniformity of culture medium addition when culturing microorganisms, thus affecting the culture and development of microorganisms in different locations within the culture vessel. This results in inconsistent development of microorganisms in different locations due to different conditions of the culture medium, which affects subsequent experimental research.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a microbial culture device for biological product research, including an incubator, wherein a visual shielding door is hinged to both sides of the front of the incubator, a glass top cover is provided on the top of the incubator, and sliding guide rails are fixedly installed on both sides of the interior of the incubator, and culture vessels are slidably connected to the inner sides of the two sliding guide rails, and the bottom sides of the culture vessels are slidably connected to the sliding guide rails via connecting slide blocks;

[0006] A top moving beam is fixedly installed at the middle of the top of the inner side of the incubator. A drive screw is rotatably connected to the inner side of the top moving beam. One end of the drive screw is fixedly connected to the output shaft of the motor, and the motor is powered by an external power source. A sliding block is slidably connected to the inner side of the top moving beam, and the sliding block is connected to the drive screw by a thread.

[0007] The bottom of the sliding block is fixedly connected to a liquid distribution box, and liquid storage boxes are fixedly installed on the top of both sides of the liquid distribution box. An external liquid replenishment pipe is connected to one side of the liquid storage box, and the sides of the liquid storage box and the liquid distribution box are connected through a connecting liquid pipe. A control valve is installed on the side of the connecting liquid pipe, and several sets of drip irrigation heads are equidistantly connected to the bottom of the liquid distribution box.

[0008] Preferably, the motor is fixedly installed on the outer side of the incubator, the inner side of the top moving beam is provided with a moving groove, the edge of the sliding block slides along the moving groove, and the drive screw is rotatably connected in the rotating groove.

[0009] Preferably, the interiors of the liquid storage box and the liquid distribution box are connected by a connecting liquid pipe, and the drip head is connected to the interior of the liquid distribution box.

[0010] Preferably, the external replenishment tube is connected through the side of the incubator, and a sealing seat is provided at the connection between the side of the incubator and the external replenishment tube;

[0011] The external replenishment pipe is detachably connected to the external nutrient solution supply pipe via a pipe seat, and the length of the external replenishment pipe is greater than the length of the top moving beam.

[0012] Preferably, a heating base box is installed at the bottom of the culture vessel, and a heat-distributing base plate is provided on the top surface of the heating base box corresponding to the bottom surface of the culture vessel. A serpentine heat pipe is embedded in the inner side of the heating base box, and both ends of the serpentine heat pipe are connected to connecting pipes for liquid inlet and outlet.

[0013] The end of the connecting tube is connected to an external heating box at the back edge of the incubator. The end of the connecting tube is connected to a circulation pump at the liquid outlet of the external heating box. Heating tubes are installed at equal intervals on the inner bottom of the external heating box, and the heating tubes are powered by an external power source.

[0014] Preferably, the interior of the heat-compensating box is filled with heat-conducting oil, the interior of the external heating box is filled with pure water, and the connecting pipe delivers the pure water to the serpentine heat pipe.

[0015] Compared with the prior art, the advantages of this utility model are: the structure of this utility model is scientific and reasonable, and it is safe and convenient to use.

[0016] 1. The sliding guide rail and connecting slide allow the entire culture vessel to be easily inserted into the incubator by pushing and pulling, facilitating the culture operation. The top moving beam, drive screw, motor, and sliding block facilitate the stable movement of the dispensing box and the storage box. This allows the culture medium to be evenly added to the culture vessel through the drip head connected to the bottom of the dispensing box when replenishing the culture. Furthermore, the stable movement of the dispensing box ensures that the culture medium is evenly added from one side of the culture vessel to the other, thus guaranteeing the uniformity of the effect of the culture medium on the microorganisms in the culture vessel and avoiding inconsistent microbial development.

[0017] Furthermore, the external replenishment tube allows for the rapid replenishment of external culture medium into the storage tank. The connection between the storage tank and the dispensing tank is achieved through a connecting tube and a control valve, facilitating the further delivery of the replenished culture medium and improving the convenience of replenishing and using the culture medium.

[0018] 2. The heating base box, heating plate, and serpentine heat pipe facilitate heating of the bottom of the culture vessel. The external heating box and heating pipes easily heat the water, and the connecting pipes and circulation pump further deliver the hot water to the serpentine heat pipes. The serpentine heat pipes then evenly distribute the heat to the heating base box, facilitating the heating of the heat transfer oil inside. The heat transfer oil then transfers the heat from the heating plate to the culture vessel. This two-step, even heating method indirectly heats the culture vessel, preventing the microorganisms inside from being stimulated by a sudden temperature increase. At the same time, this heating method can more evenly and comprehensively distribute heat into the culture vessel, ensuring the effective cultivation of microorganisms. Attached Figure Description

[0019] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0020] In the attached diagram:

[0021] Figure 1 This is a schematic diagram of the structure of this utility model;

[0022] Figure 2 This is a schematic diagram of the top movable beam of this utility model;

[0023] Figure 3 This is a schematic diagram of the installation structure of the liquid separator of this utility model;

[0024] Figure 4 This is a schematic diagram of the internal structure of the heat-compensating bottom box of this utility model;

[0025] The diagram is labeled as follows: 1. Incubator; 2. Visual shielded door; 3. Glass top cover; 4. Sliding guide rail; 5. Culture vessel; 6. Connecting slide; 7. Top moving beam; 8. Drive screw; 9. Motor; 10. Sliding block; 11. Dispensing box; 12. Storage box; 13. External replenishment pipe; 14. Connecting pipe; 15. Control valve; 16. Drip head; 17. Temperature replenishment box; 18. Heating base plate; 19. Serpentine heat pipe; 20. Connecting pipe; 21. External heating box; 22. Circulation pump; 23. Heating tube. Detailed Implementation

[0026] The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are for illustration and explanation only and are not intended to limit the present invention.

[0027] Example: Figure 1-4 As shown, this utility model provides a technical solution, a microbial culture device for biological product research, including an incubator 1, with a visual shielding door 2 hinged to both sides of the front of the incubator 1, a glass top cover 3 on the top of the incubator 1, and sliding guide rails 4 fixedly installed on both sides of the interior of the incubator 1. A culture vessel 5 is slidably connected to the inner side of the two sliding guide rails 4, and the bottom sides of both sides of the culture vessel 5 are slidably connected to the sliding guide rails 4 through connecting slides 6.

[0028] A top moving beam 7 is fixedly installed at the middle of the top of the inner side of the incubator 1. A drive screw 8 is rotatably connected to the inner side of the top moving beam 7. One end of the drive screw 8 is fixedly connected to the output shaft of the motor 9, and the motor 9 is powered by an external power source. A sliding block 10 is slidably connected to the inner side of the top moving beam 7. The sliding block 10 is connected to the drive screw 8 by a thread.

[0029] A dispensing box 11 is fixedly connected to the bottom of the sliding block 10. Storage boxes 12 are fixedly installed on both sides of the top of the dispensing box 11. A motor 9 is fixedly installed on the outer side of the incubator 1. A moving groove is provided on the inner side of the top moving beam 7. The edge of the sliding block 10 slides along the moving groove, and the drive screw 8 is rotatably connected to the rotating groove, facilitating stable movement of the dispensing box 11 and the storage box 12. An external replenishment pipe 13 is connected to one side of the storage box 12. The external replenishment pipe 13 passes through and connects to the side of the incubator 1. A sealing seat is provided at the connection point between the side of the incubator 1 and the external replenishment pipe 13, facilitating the connection of the external replenishment pipe 13. The external replenishment pipe 13 allows for the rapid replenishment of external culture medium to the storage box 1. 2. The external replenishment pipe 13 is detachably connected to the external nutrient solution supply pipe through the pipe seat. The length of the external replenishment pipe 13 is greater than the length of the top moving beam 7, so that the external replenishment pipe 13 will not affect the movement of the dispensing box 11 and the storage box 12. The sides of the storage box 12 and the dispensing box 11 are connected by the connecting pipe 14. A control valve 15 is installed on the side of the connecting pipe 14. The interiors of the storage box 12 and the dispensing box 11 are connected by the connecting pipe 14. The drip head 16 is connected to the interior of the dispensing box 11. The interiors of the storage box 12 and the dispensing box 11 are connected by the connecting pipe 14 and the control valve 15 to facilitate the delivery of the culture medium. Several sets of drip heads 16 are equidistantly connected to the bottom of the dispensing box 11.

[0030] A heating base box 17 is installed at the bottom of the culture vessel 5. A heat distribution plate 18 is provided on the top surface of the heating base box 17 corresponding to the bottom surface of the culture vessel 5. A serpentine heat pipe 19 is embedded in the inner side of the heating base box 17. Both ends of the serpentine heat pipe 19 are connected to the liquid inlet and outlet ends with connecting pipes 20.

[0031] The end of the connecting pipe 20 is connected to an external heating box 21 at the back edge of the incubator 1. The end of the connecting pipe 20 is connected to a circulation pump 22 at the liquid outlet of the external heating box 21. The interior of the supplementary heating box 17 is filled with heat-conducting oil, and the interior of the external heating box 21 is filled with purified water. The connecting pipe 20 delivers purified water to the serpentine heat pipe 19. The connecting pipe 20 and the circulation pump 22 deliver hot water to the serpentine heat pipe 19, which facilitates the uniform introduction of heat into the heat-conducting oil in the supplementary heating box 17. The heated heat-conducting oil allows heat to be introduced from the heat distribution plate 18 into the culture vessel 5. Heating pipes 23 are installed at equal intervals on the inner bottom of the external heating box 21. The heating pipes 23 are powered by an external power source.

[0032] The working principle and usage process of this utility model: In the actual application of this microbial culture device for biological product research, the visible shielding door 2 and glass top cover 3 on the front side of the culture chamber 1 facilitate the observation of the culture vessel 5 inside the culture chamber 1 from the outside, so as to understand the culture status of microorganisms. The culture vessel 5 can be easily inserted into the culture chamber 1 by pushing and pulling through the sliding guide rail 4 and the connecting slide 6, thus facilitating the culture operation of the culture vessel 5.

[0033] During the microbial culture process, when it is necessary to apply the culture medium to the microorganisms in the culture vessel 5, the external replenishment tube 13 is used to quickly replenish the external culture medium into the storage box 12. The connecting tube 14 and the control valve 15 are used to connect the storage box 12 to the inside of the dispensing box 11, so as to quickly transport the culture medium replenished in the storage box 12 to the dispensing box 11. The control valve 15 can control the opening and closing of the connecting tube 14.

[0034] When replenishing the culture medium, the top moving beam 7, drive screw 8, motor 9 and sliding block 10 facilitate the stable movement of the dispensing box 11 and the storage box 12. This allows the culture medium to be evenly added to the culture vessel 5 through the drip head 16 connected to the bottom of the dispensing box 11. With the stable movement of the dispensing box 11, the culture medium can be evenly added from one side of the culture vessel 5 to the other, thereby ensuring the uniformity of the effect of the culture medium on the microorganisms in the culture vessel 5 and avoiding inconsistent microbial development.

[0035] When it is necessary to supplement the temperature during the microbial culture process, the water is first heated by the external heating box 21 and the heating tube 23. Then, the hot water is transported to the serpentine heat pipe 19 by the connecting pipe 20 and the circulating pump 22. The heat of the hot water is then evenly introduced into the supplementary heating box 17 by the serpentine heat pipe 19, so as to achieve uniform heating of the heat transfer oil in the supplementary heating box 17.

[0036] After the heat-conducting oil in the heating base box 17 is heated, the heat is transferred from the heating base plate 18 to the culture vessel 5 through the heat-conducting oil. In this way, the culture vessel 5 is indirectly heated through a two-step uniform heating method, which avoids the microorganisms in the culture vessel 5 from being stimulated by the sudden increase in temperature. At the same time, this heating method can more evenly and comprehensively transfer heat into the culture vessel 5, ensuring the microbial culture effect in the culture vessel 5.

[0037] Finally, it should be noted that the above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A microbial culture device for biological product research, comprising an incubator (1), wherein a visual shielding door (2) is hinged to both sides of the front of the incubator (1), and a glass top cover (3) is provided on the top of the incubator (1), characterized in that: The incubator (1) has sliding guide rails (4) fixedly installed on both sides of its interior. The two sliding guide rails (4) are slidably connected to the inner sides of the culture vessel (5). The bottom sides of the culture vessel (5) are slidably connected to the sliding guide rails (4) through connecting slides (6). A top moving beam (7) is fixedly installed at the middle of the top of the inner side of the incubator (1). A drive screw (8) is rotatably connected to the inner side of the top moving beam (7). One end of the drive screw (8) is fixedly connected to the output shaft of the motor (9), and the motor (9) is powered by an external power source. A sliding block (10) is slidably connected to the inner side of the top moving beam (7). The sliding block (10) and the drive screw (8) are connected by a thread. The bottom end of the sliding block (10) is fixedly connected to a liquid distribution box (11). Liquid storage boxes (12) are fixedly installed on the top of both sides of the liquid distribution box (11). An external replenishment pipe (13) is connected to one side of the liquid storage box (12). The side of the liquid storage box (12) and the side of the liquid distribution box (11) are connected through a connecting liquid pipe (14). A control valve (15) is installed on the side of the connecting liquid pipe (14). Several sets of drip irrigation heads (16) are equidistantly connected to the bottom end of the liquid distribution box (11).

2. The microbial culture device for biological product research according to claim 1, characterized in that: The motor (9) is fixedly installed on the outer side of the incubator (1). The inner side of the top moving beam (7) is provided with a moving groove. The edge of the sliding block (10) slides along the moving groove, and the driving screw (8) is rotatably connected in the rotating groove.

3. The microbial culture device for biological product research according to claim 1, characterized in that: The interiors of the liquid storage box (12) and the liquid distribution box (11) are connected by a connecting liquid pipe (14), and the drip head (16) is connected to the interior of the liquid distribution box (11).

4. The microbial culture device for biological product research according to claim 1, characterized in that: The external replenishment tube (13) is connected through the side of the incubator (1), and a sealing seat is provided at the connection between the side of the incubator (1) and the external replenishment tube (13); The external replenishment pipe (13) is detachably connected to the external nutrient solution supply pipe through the pipe seat, and the length of the external replenishment pipe (13) is greater than the length of the top moving beam (7).

5. The microbial culture device for biological product research according to claim 1, characterized in that: The bottom of the culture vessel (5) is equipped with a heat-compensating bottom box (17). The top surface of the heat-compensating bottom box (17) is provided with a heat-distributing bottom plate (18) corresponding to the bottom surface of the culture vessel (5). A serpentine heat pipe (19) is embedded in the inner side of the heat-compensating bottom box (17). Both ends of the serpentine heat pipe (19) are connected to connecting pipes (20). The end of the connecting tube (20) is connected to an external heating box (21) at the back edge of the incubator (1). The end of the connecting tube (20) is connected to a circulating pump (22) at the liquid outlet of the external heating box (21). Heating tubes (23) are installed at equal intervals on the bottom inner side of the external heating box (21). The heating tubes (23) are powered by an external power source.

6. The microbial culture device for biological product research according to claim 5, characterized in that: The interior of the heat-conducting bottom box (17) is filled with heat-conducting oil, the interior of the external heating box (21) is filled with pure water, and the connecting pipe (20) delivers the pure water to the serpentine heat pipe (19).

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