Pharmaceutical fermentation device
By combining mechanical defoaming and defoaming agents, the problem of foam hindering oxygen absorption in traditional fermentation devices is solved, fermentation efficiency is improved, foam of different sizes is effectively eliminated, and the effect of the fermentation process is enhanced.
Patent Information
- Application Number
- CN202423303625.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-31
- Publication Date
- 2026-01-13
- Estimated Expiration
- 2034-12-31
AI Technical Summary
In traditional fermentation equipment, foam can easily hinder the absorption of oxygen by microorganisms during fermentation, leading to reduced fermentation efficiency. Existing defoamers have limited effectiveness in eliminating small bubbles and flowing foam.
By employing a combination of mechanical defoaming and defoaming agents, and through the design of the stirring structure and defoaming components, effective elimination of foams of different sizes can be achieved.
It improves fermentation efficiency, enabling microorganisms to make fuller use of oxygen and nutrients, thus enhancing the effectiveness of the fermentation process.
Smart Images
Figure CN223793149U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical technology, specifically to a fermentation device for pharmaceutical use. Background Technology
[0002] Fermentation technology plays a vital role in the pharmaceutical industry. It utilizes the fermentation action of microorganisms and precisely controls the fermentation process through a series of technical means to achieve large-scale production of fermented products. It plays a crucial role in the pharmaceutical process and provides strong support for the development of the pharmaceutical industry.
[0003] In traditional fermentation equipment, due to the large amount of protein in the fermentation broth, air is mechanically dispersed in the fermentation broth under conditions such as aeration and stirring, forming foam. If the foam increases, it can easily hinder the absorption of oxygen by microorganisms, which is not conducive to fermentation and biosynthesis and reduces fermentation efficiency. Although large bubbles that are initially formed can be broken up by defoamers, the spacing of the defoamer's rake teeth is fixed, and its effect on eliminating small bubbles and flowing foam is limited. Utility Model Content
[0004] I. Technical problems to be solved
[0005] The technical problem to be solved by this utility model is to overcome the above-mentioned technical difficulties and provide a device that uses a combination of mechanical defoaming and defoaming agent to eliminate foam of different sizes, so that microorganisms can make fuller use of oxygen and nutrients, thereby improving fermentation efficiency.
[0006] II. Technical Solution
[0007] To solve the above-mentioned technical problems, the technical solution provided by this utility model is as follows: a pharmaceutical fermentation device, including a base plate, a fermentation tank provided above the base plate, and support legs provided at the four corners of the bottom of the fermentation tank, the bottom ends of the support legs being fixedly connected to the base plate, and further including:
[0008] Electric telescopic rod and cover; one side of the base plate is provided with an inverted L-shaped plate, the electric telescopic rod is directly fixed to the L-shaped plate, and the cover is directly fixed to the telescopic end of the electric telescopic rod through a connecting frame, for use with fermentation tank;
[0009] The system includes a motor, a stirring structure, and a defoaming component. The stirring structure is located at the bottom of the sealed lid and is driven by the motor to mix and stir the inside of the fermentation tank. The defoaming component is located above the stirring structure and rotates with it to eliminate foam of different sizes produced during fermentation.
[0010] As an improvement, the stirring structure includes a stirring shaft and stirring blades; the stirring shaft is driven by a motor, and multiple stirring blades are evenly distributed on both sides of the stirring shaft. Both the stirring shaft and the stirring blades are hollow structures and are interconnected. Each stirring blade is provided with multiple through holes.
[0011] As an improvement, the motor is fixedly mounted on the top of the cover, and the output end of the motor is provided with a first gear, and the end of the stirring shaft extending outside the cover is provided with a second gear that meshes with the first gear.
[0012] As an improvement, the defoaming assembly includes a fixing plate and defoaming rods; the fixing plate is fixedly connected to both sides of the stirring shaft and located above the stirring blades. Each fixing plate is provided with an opening slot, and multiple defoaming rods are inserted into the opening slots and extend to the outside. The bottom ends of the defoaming rods are all locked and fixed by threaded nuts.
[0013] As an improvement, the top of the cap is provided with a vent pipe, the vent pipe is provided with a valve, the cap is provided with a pressure gauge, the bottom of the cap is provided with a temperature sensor, the top of the cap is provided with a controller electrically connected to the pressure gauge and the temperature sensor, and the fermentation tank is provided with a control panel connected to the controller.
[0014] III. Beneficial Effects
[0015] The advantages of this utility model compared with the prior art are as follows:
[0016] 1. With the fixed plate, opening groove, defoaming rod and nut, it can not only rotate with the stirring shaft, but also directly break up the foam with the defoaming rod. It is also easy to flexibly adjust the distance between the defoaming rods, which is suitable for foams of different sizes.
[0017] 2. The motor, stirring shaft, stirring blades, first gear, and second gear can stir and mix the medicine in the fermentation tank. In addition, the stirring shaft and stirring blades are hollow and interconnected. When the defoamer mixture is added to the stirring shaft, it can be evenly sprinkled into the fermentation tank with the help of the through holes. When used in conjunction with mechanical defoaming, the overall effect is good. Attached Figure Description
[0018] Figure 1 This is a three-dimensional schematic diagram of a pharmaceutical fermentation device according to the present invention. Figure 1 .
[0019] Figure 2 This is a three-dimensional schematic diagram of a pharmaceutical fermentation device according to the present invention. Figure 2 .
[0020] Figure 3 This is a schematic diagram of the structure of the sealing cap for a pharmaceutical fermentation device according to this utility model. Figure 1 .
[0021] Figure 4 This is a schematic diagram of the structure of the sealing cap for a pharmaceutical fermentation device according to this utility model. Figure 2 .
[0022] Figure 5 This is a cross-sectional structural diagram of the sealing structure of a pharmaceutical fermentation device according to the present invention.
[0023] Figure 6 This utility model relates to a fermentation device for pharmaceutical use. Figure 5 Enlarged detail of part A.
[0024] As shown in the figure: 1. Base plate; 2. Fermentation tank; 3. Support leg; 4. Cover; 5. L-shaped plate; 6. Electric telescopic rod; 7. Connecting frame; 8. Motor; 9. Stirring shaft; 10. Stirring blade; 11. Through hole; 12. First gear; 13. Second gear; 14. Fixing plate; 15. Opening slot; 16. Defoaming rod; 17. Nut; 18. Vent pipe; 19. Pressure gauge; 20. Temperature sensor; 21. Controller; 22. Control panel. Detailed Implementation
[0025] In the description of this utility model, it should be understood that the terms "center," "lateral," "upper," "lower," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating orientation or positional relationships based on the orientation or positional relationships shown in the accompanying drawings, are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more. Additionally, the term "comprising" and any variations thereof are intended to cover non-exclusive inclusion.
[0026] The present invention will now be described in further detail with reference to the accompanying drawings.
[0027] Combined with appendix Figure 1 and attached Figure 2A pharmaceutical fermentation device includes a base plate 1, a fermentation tank 2 on top of the base plate 1, and support legs 3 at the four corners of the bottom of the fermentation tank 2. The bottom ends of the support legs 3 are fixedly connected to the base plate 1. The device also includes an electric telescopic rod 6 and a cover 4. An inverted L-shaped plate 5 is provided on one side of the base plate 1. The electric telescopic rod 6 is directly fixedly connected to the L-shaped plate. The cover 4 is directly fixed to the telescopic end of the electric telescopic rod 6 through a connecting frame 7. The cover 4 is used in conjunction with the fermentation tank 2. As the electric telescopic rod 6 continuously contracts and extends, it can drive the cover 4 to cover or remove the fermentation tank 2.
[0028] Combined with appendix Figure 3 and attached Figure 4 The fermentation tank 2 is equipped with a motor 8 and a stirring structure. The stirring structure is located at the bottom of the cover 4 and is driven by the motor 8 to mix and stir the contents of the fermentation tank 2. The stirring structure includes a stirring shaft 9 and stirring blades 10. The stirring shaft 9 is driven by the motor 8, and multiple stirring blades 10 are evenly distributed on both sides of the stirring shaft 9. Both the stirring shaft 9 and the stirring blades 10 are hollow and interconnected. Each stirring blade 10 has multiple through holes 11. The motor 8 is fixedly located at the top of the cover 4, and the output end of the motor 8 is equipped with a first gear 12. The end of the stirring shaft 9 extending outside the cover 4 is equipped with a second gear 13 that meshes with the first gear 12. The motor 8 drives the first gear 12 to rotate continuously, and the second gear 13 meshing with the first gear 12 rotates accordingly, thereby driving the stirring shaft 9 to rotate continuously. The sealing plug at the top of the stirring shaft 9 is opened, and the defoaming agent is added into the stirring shaft 9. Since both the stirring shaft 9 and the stirring blades 10 are hollow and interconnected, the agent can be evenly sprinkled into the fermentation tank 2 through the through holes 11 to directly defoam the contents of the fermentation tank 2.
[0029] Combined with appendix Figure 5 and attached Figure 6 The defoaming component is positioned above the stirring structure and rotates with it to eliminate foam of different sizes generated during fermentation. The defoaming component includes a fixing plate 14 and defoaming rods 16. The fixing plate 14 is fixedly connected to both sides of the stirring shaft 9 and located above the stirring blades 10. Each fixing plate 14 has an opening slot 15, into which multiple defoaming rods 16 are inserted and extend to the outside. The bottom ends of the defoaming rods 16 are locked in place by threaded nuts 17. Loosening the nuts 17 allows for flexible adjustment of the spacing between the defoaming rods 16, and the nuts 17 also lock the defoaming rods 16 in place. The defoaming rods 16 and the fixing plate 14 rotate with the stirring shaft 9, allowing for direct breaking of the floating foam.
[0030] Combined with appendix Figure 3 and attached Figure 4The top of the cover 4 is provided with a vent pipe 18, and a valve is provided on the vent pipe 18. The cover 4 is provided with a pressure gauge 19, and the bottom of the cover 4 is provided with a temperature sensor 20. The top of the cover 4 is provided with a controller 21 that is electrically connected to the pressure gauge 19 and the temperature sensor 20. The fermentation tank 2 is provided with a control panel 22 that is connected to the controller 21. The pressure gauge 19 and the temperature sensor 20 can be used to monitor the temperature and pressure inside the fermentation tank 2 in real time and transmit the data to the controller 21. The controller 21 transmits the data to the control panel 22 for easy real-time viewing. Moreover, opening the valve can be used to ventilate and release pressure inside the tank through the vent pipe 18. The overall structure is simple and has multiple functions.
[0031] In specific implementation of this utility model:
[0032] First, start the electric telescopic rod 6 to continuously retract, driving the cap 4 away from the fermentation tank 2. Pour the medicines to be fermented into the fermentation tank 2, loosen the nut 17, flexibly adjust the spacing between the defoaming rods 16, and use the nut 17 to lock and fix the defoaming rods 16 one by one.
[0033] Then, the electric telescopic rod 6 is started to extend continuously, causing the cover 4 to move down and cover the fermentation tank 2. The motor 8 is started, and the motor 8 drives the first gear 12 to rotate continuously. The second gear 13, which meshes with the first gear 12, also rotates, thereby driving the stirring shaft 9 to rotate continuously, mixing and stirring the internal medicine to accelerate fermentation.
[0034] At this time, the defoaming rod 16 and the fixing plate 14 rotate with the stirring shaft 9, which can directly break up the floating foam. In addition, the sealing plug at the top of the stirring shaft 9 can be opened to put the defoaming agent into the stirring shaft 9. Since the stirring shaft 9 and the stirring blade 10 are hollow structures and interconnected, the agent can be evenly sprinkled into the fermentation tank 2 through the through hole 11 to directly defoam the medicine inside. This achieves the combined use of mechanical defoaming and defoaming agent, resulting in a good overall defoaming effect. This allows the microorganisms to make fuller use of oxygen and nutrients, thereby improving the fermentation efficiency.
[0035] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
[0036] The present invention and its embodiments have been described above. This description is not restrictive, and the accompanying drawings are only one embodiment of the present invention; the actual structure is not limited thereto. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the inventive spirit of the present invention, such designs should fall within the protection scope of the present invention.
Claims
1. A pharmaceutical fermentation device, comprising a base plate (1), a fermentation barrel (2) is arranged above the base plate (1), support legs (3) are arranged at the bottom of the four corners of the fermentation barrel (2), and the bottom of each support leg (3) is fixedly connected with the base plate (1), characterized in that, Also includes: Electric telescopic rod (6) and cover (4); One side of the bottom plate (1) is provided with an inverted L-shaped plate (5), the electric telescopic rod (6) is directly fixedly connected on the L-shaped plate, the cover (4) is directly fixed on the telescopic end of the electric telescopic rod (6) through the connecting frame (7), and is used in cooperation with the fermentation barrel (2); Motor (8), stirring structure and defoaming assembly; The stirring structure is arranged at the bottom end of the cover (4) and is driven by the motor (8) to mix and stir the inside of the fermentation barrel (2); the defoaming assembly is arranged above the stirring structure and rotates with the stirring structure, and is used for eliminating different sizes of foam generated in fermentation.
2. The fermentation device for pharmacy according to claim 1, characterized in that: The stirring structure comprises a stirring shaft (9) and stirring blades (10); the stirring shaft (9) is driven by the motor (8), and a plurality of stirring blades (10) are uniformly distributed on both sides of the stirring shaft (9); the stirring shaft (9) and the stirring blades (10) are hollow structures and are in communication with each other; and a plurality of through holes (11) are arranged on the stirring blades (10).
3. The apparatus according to claim 2, wherein: The motor (8) is fixedly arranged at the top end of the cover (4), and a first gear (12) is arranged at the output end of the motor (8); and a second gear (13) meshing with the first gear (12) is arranged at the end of the stirring shaft (9) extending out of the cover (4).
4. The fermentation device for pharmacy according to claim 2, characterized in that: The defoaming assembly comprises a fixed plate (14) and a defoaming rod (16); the fixed plate (14) is fixedly connected on both sides of the stirring shaft (9) and above the stirring blades (10); a plurality of open grooves (15) are arranged on the fixed plate (14); a plurality of defoaming rods (16) are inserted into the open grooves (15) and extend to the outside; and the bottom ends of the defoaming rods (16) are locked and fixed by threaded nuts (17).
5. The apparatus for fermentation of claim 1, wherein: A vent pipe (18) is arranged at the top end of the cover (4); a valve is arranged on the vent pipe (18); a pressure gauge (19) is arranged on the cover (4); a temperature sensor (20) is arranged at the bottom end of the cover (4); a controller (21) electrically connected with the pressure gauge (19) and the temperature sensor (20) is arranged at the top end of the cover (4); and a control panel (22) connected with the controller (21) is arranged on the fermentation barrel (2).