Plasma separation device for hematotrophin production process
The plasma separation device, designed with a rotating chamber and lifting slide bar, solves the problems of large size and difficult cleaning of traditional devices, achieving efficient separation and all-round cleaning, and ensuring equipment hygiene.
Patent Information
- Application Number
- CN202423279962.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2026-01-16
- Estimated Expiration
- 2034-12-30
AI Technical Summary
Traditional plasma separation devices are bulky, inconvenient to carry, and difficult to clean, which affects the separation effect.
A plasma separation device comprising a rotating housing, an external gear ring, and a drive gear was designed, which, combined with a lifting slide bar and a cleaning brush, enables plasma separation and all-round cleaning.
It improves plasma separation efficiency, ensures equipment hygiene, and reduces the risk of cross-contamination.
Smart Images

Figure CN223800699U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of plasma separation technology, specifically to a plasma separation device used in the production process of gonadotropins. Background Technology
[0002] Serum gonadotropins are serum gonadotropins extracted from the serum or plasma of pregnant mare. Calculated on a dried basis, the potency of each 1 mg should not be less than 2000 units. During production, appropriate processing methods are required to eliminate or inactivate any viruses, such as equine infectious anemia virus and equine influenza virus. It is a white or off-white powder. During the production of serum gonadotropins, plasma separation is necessary.
[0003] Traditional plasma separation is generally carried out using a plasma separator, but these separators are bulky and inconvenient to carry and use at any time. Current small plasma separation devices typically place blood in a separation tank and then drive the tank to rotate to separate the plasma. However, after use, it is inconvenient to clean the separation tank, which affects the plasma separation effect in the next cycle. Therefore, we propose a plasma separation device for the production process of gonadotropins. Utility Model Content
[0004] The purpose of this invention is to provide a plasma separation device for the production process of gonadotropins, so as to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, this utility model provides the following technical solution: a plasma separation device for the production process of gonadotropins, comprising a support base and a box rotatably mounted on top of the support base, wherein an injection port is provided at the top of the box, an installation cover is installed on the top of the box, a rotating seat is rotatably connected to the top of the installation cover, a boss is integrally provided on the top of the rotating seat, and an adjustable lifting slide rod is provided inside the boss, the bottom of the lifting slide rod extends into the box and is fixedly connected to the lifting seat, a disc-shaped brush is installed at the bottom of the lifting seat, and an annular brush is installed on the outer side of the lifting seat, with the bristles of the annular brush contacting the inner wall of the box.
[0006] Preferably, the lifting slide rod has a square cross-section, and the surface of the lifting slide rod is provided with positioning holes at equal intervals along the vertical direction. The surface of the boss is provided with a pin, and the end of the pin is slidably inserted into the positioning hole.
[0007] Preferably, an L-shaped fixing frame is fixedly installed on the outside of the support base, an external gear ring is fixedly connected to the outside of the housing, a drive motor is fixedly installed inside the L-shaped fixing frame, and a drive gear is fixedly connected to the output shaft end of the drive motor through the L-shaped fixing frame, and the drive gear and the external gear ring are meshed together.
[0008] Preferably, the inner wall of the support base is provided with an annular groove, and an annular sliding plate is integrally provided on the outer side of the bottom end of the box, and the annular sliding plate is slidably connected in the annular groove.
[0009] Preferably, the bottom of the support base is fixedly connected with three support legs at equal intervals, and storage drawer boxes are provided at equal intervals on the outer side of the support base.
[0010] Preferably, a discharge port is provided at the center of the bottom of the box, and a control valve is provided on the outside of the discharge port.
[0011] Preferably, a push-pull plate is provided at the top of the lifting slide bar.
[0012] Preferably, a lever is fixedly connected to the outer side of the rotating seat.
[0013] Compared with the prior art, the beneficial effects of this utility model are:
[0014] 1. This utility model, through its built-in rotating housing, combined with the design of an external gear ring and a drive gear, can effectively separate plasma from blood using centrifugal force, thus improving separation efficiency.
[0015] 2. The design of the lifting slide and lifting seat of this utility model allows the cleaning brush to be adjusted in height as needed, so that it can fit more closely to the inner wall of the box and achieve all-round cleaning without dead angles. Through the combination of disc brush and ring brush, not only can the side wall of the box be cleaned, but the bottom can also be cleaned in a special way, ensuring the hygiene of the equipment and reducing the risk of cross-contamination. Attached Figure Description
[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0017] Figure 2 This is a cross-sectional view of the present invention.
[0018] Figure 3 This is a schematic diagram of the annular groove structure on the inner wall of the support base of this utility model.
[0019] In the diagram: 1. Support base; 2. Box body; 3. Mounting cover; 4. Inlet; 5. Rotating seat; 6. Boss; 7. Lifting slide bar; 8. Positioning hole; 9. Pin; 10. Toggle handle; 11. L-shaped fixing bracket; 12. Drive motor; 13. Drive gear; 14. External gear ring; 15. Lifting seat; 16. Annular brush; 17. Disc brush; 18. Storage drawer box; 19. Sliding plate; 20. Discharge port; 21. Annular groove; 22. Annular sliding plate; 23. Support foot. Detailed Implementation
[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0021] Please see Figure 1-3 This utility model provides a technical solution: a plasma separation device for the production process of gonadotropins, including a support base 1 and a box 2 rotatably mounted on the top of the support base 1. The top of the box 2 is provided with an injection port 4. An installation cover 3 is installed on the top of the box 2. A rotating seat 5 is rotatably connected to the top of the installation cover 3. A boss 6 is integrally provided on the top of the rotating seat 5. An adjustable lifting slide rod 7 is provided inside the boss 6. The bottom of the lifting slide rod 7 extends into the box 2 and is fixedly connected to a lifting seat 15. A disc-shaped brush 17 is installed at the bottom of the lifting seat 15. An annular brush 16 is installed on the outside of the lifting seat 15. The bristles of the annular brush 16 are in contact with the inner wall of the box 2.
[0022] It should be noted that, in use, the lifting slide plate 19 is pulled upwards to slide the lifting slide rod 7 out of the housing 2. The lifting seat 15 at the bottom of the lifting slide rod 7 fits tightly against the bottom of the mounting cover 3. The position of the lifting slide rod 7 is then fixed by the pin 9. Blood is placed inside the housing 2 through the injection port 4. Then, the drive motor 12 is controlled to rotate the drive gear 13. The housing 2 rotates through the meshing connection between the drive gear 13 and the outer gear ring 14 on the outside of the housing 2. The device is equipped with a control system to control the rotation speed of the housing 2 to separate the blood. After the plasma is separated, remove the pin 9 and inject cleaning fluid into the tank 2 through the injection port 4. Then, pull the push-pull plate 19 to move the piston up and down. The ring brush 16 on the outside of the push-pull plate 19 can thoroughly clean the inner wall of the tank 2. Push the lifting seat 15 to the bottom of the inner wall of the tank 2, and then turn the lever 10 to control the rotation of the rotating seat 5. Use the disc brush 17 to clean the bottom of the inner wall of the tank 2. Finally, open the control valve on the discharge port 20 to discharge the sewage, thus achieving the purpose of thoroughly cleaning the inside of the tank 2.
[0023] The lifting slide rod 7 has a square cross-section. Positioning holes 8 are equidistantly opened on the surface of the lifting slide rod 7 along the vertical direction. A pin 9 is provided on the surface of the boss 6. The end of the pin 9 is slidably inserted into the positioning hole 8.
[0024] It should be noted that the design of the lifting slide 7 and the lifting seat 15 allows the cleaning brush to be adjusted in height as needed, so that it can fit more closely to the inner wall of the box 2 and achieve all-round cleaning without dead angles. The lifting slide 7 has multiple positioning holes 8. After adjusting the position of the lifting slide 7, the lifting slide 7 can be fixed in the rotating seat 5 by the pin 9.
[0025] An L-shaped fixing bracket 11 is fixedly installed on the outside of the support base 1. An external gear ring 14 is fixedly connected to the outside of the housing 2. A drive motor 12 is fixedly installed inside the L-shaped fixing bracket 11. The output shaft end of the drive motor 12 passes through the L-shaped fixing bracket 11 and is fixedly connected to a drive gear 13. The drive gear 13 and the external gear ring 14 are meshed together.
[0026] It should be noted that the drive motor 12 is controlled to rotate the drive gear 13, and the drive gear 13 and the outer gear ring 14 on the outside of the housing 2 are meshed to rotate the housing 2. The device is equipped with a control system to control the rotation speed of the housing 2 in order to separate the plasma.
[0027] The inner wall of the support base 1 is provided with an annular groove 21, and the outer side of the bottom end of the box body 2 is integrally provided with an annular sliding plate 22, which is slidably connected in the annular groove 21.
[0028] It should be noted that during the rotation of the box 2, the annular sliding plate 22 at the bottom of the box 2 is slidably connected to the annular groove 21 on the inner wall of the support base 1, which ensures the stable rotation of the box 2.
[0029] The bottom of the support base 1 is fixedly connected with three support legs 23 at equal intervals, and storage drawer boxes 18 are provided at equal intervals on the outer side of the support base 1.
[0030] It should be noted that the three support feet 23 at the bottom of the support base 1 enable the plasma separation device to be placed stably on the support plane. Bolt holes for bolt fixing are provided at the bottom of the three support feet 23. The device can be stably installed on the support plane by bolts to ensure the stability of the device during the plasma separation process.
[0031] The bottom center of the box 2 is provided with a discharge port 20, and a control valve is provided on the outside of the discharge port 20.
[0032] It should be noted that the discharge port 20 is designed to facilitate the discharge of materials inside the box 2, and the control valve is used to control the opening and closing of the discharge port 20.
[0033] A push-pull plate 19 is provided on the top of the lifting slide bar 7.
[0034] It should be noted that the user can easily adjust the position of the lifting seat 15 by operating the push-pull plate 19.
[0035] A toggle handle 10 is fixedly connected to the outer side of the rotating seat 5.
[0036] It should be noted that by controlling the rotation of the base 5 by turning the lever 10, the operation becomes intuitive and simple, reducing the difficulty of operation.
[0037] In the description of this utility model, it should be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "side", "top", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.
[0038] Furthermore, the terms "first," "second," "third," and "fourth" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first," "second," "third," or "fourth" may explicitly or implicitly include at least one of those features.
[0039] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.
[0040] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A plasma separation apparatus for use in a process for the production of a blood gonadotropin, characterized in that, The utility model provides a kind of box for cleaning, including support seat (1) and rotatable box (2) arranged in the top of support seat (1), and the top of box (2) is provided with injection port (4), the top of the installation cover (3) is installed in the top of box (2), the top of the installation cover (3) is rotatably connected with rotating seat (5), the top of the rotating seat (5) is integrally provided with boss (6), and the boss (6) is provided with liftable adjusting liftable slide rod (7), the bottom of the liftable slide rod (7) is fixedly connected with lifting seat (15) in the inside of box (2), the bottom of the lifting seat (15) is installed disc-shaped brush (17), and the outer side of lifting seat (15) is installed annular brush (16), and the bristle of annular brush (16) is in contact with the inner wall of box (2).
2. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The cross section of the liftable slide rod (7) is square structure, the surface of the liftable slide rod (7) is equidistantly provided with positioning hole (8) along vertical direction, the surface of the boss (6) is provided with bolt (9), and the end of the bolt (9) is slidingly inserted into the positioning hole (8).
3. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The outer side of the support seat (1) is fixedly installed with L-shaped fixing frame (11), the outer side of the box (2) is fixedly connected with outer gear ring (14), the L-shaped fixing frame (11) is fixedly installed with driving motor (12), and the output shaft end of the driving motor (12) is fixedly connected with driving gear (13) penetrating through L-shaped fixing frame (11), and the driving gear (13) and outer gear ring (14) are engagedly connected.
4. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The inner wall of the support seat (1) is provided with annular groove (21), and the outer side of the bottom end of the box (2) is integrally provided with annular slide plate (22), and the annular slide plate (22) is slidingly connected in the annular groove (21).
5. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The bottom of the support seat (1) is equidistantly fixedly connected with three supporting legs (23), and the outer side of the support seat (1) is equidistantly provided with storage drawer box (18).
6. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The bottom center of the box (2) is provided with discharge port (20), and the outer side of the discharge port (20) is provided with control valve.
7. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The top of the liftable slide rod (7) is provided with push-pull plate (19).
8. The plasma separation apparatus for a process of blood gonadotropin production according to claim 1, characterized by: The outer side of the rotating seat (5) is fixedly connected with the knob (10).