PCR (Polymerase Chain Reaction) tube uncovering device applicable to multiple tube diameters

Abstract

The utility model discloses a PCR (Polymerase Chain Reaction) tube uncapping device suitable for multiple tube diameters. The PCR tube uncapping device comprises a main shell, an uncapping execution unit and a prying head conversion unit, wherein the prying head conversion unit is used for switching the types of prying heads in the uncapping execution unit; the interval adjusting transmission unit is used for adjusting the adjacent intervals of the horizontal sliding blocks at equal intervals, and the interval adjusting triggering unit is used for manually controlling and triggering the adjusting amount of the interval adjusting transmission unit. Equidistant and simultaneous adjustment of cap opening point spacing is realized by adopting a cross connecting rod mechanism, and a sliding groove type interference preventing assembly is arranged below the cross connecting rod mechanism, so that the technical problem of structure jamming caused by vertical movement of the connecting rod mechanism in the moving process is solved; according to the cap opening device, the cap opening requirements of different batches of PCR pipes with different pipe diameters are met by adopting a rotary clamping structure and combining a plurality of cap prying pipes which are arranged in an array and have different diameters, and the technical problem that in the prior art, cap opening operation is only suitable for a single PCR pipe diameter, cap opening diameter adaptive adjustment of different pipe diameters cannot be achieved, and the application range is limited is solved.

Description

TECHNICAL FIELD

[0001] The embodiment of the utility model belongs to PCR tube uncapping technical field, more particularly, relate to a kind of PCR tube uncapping device of multi-pipe diameter application. BACKGROUND

[0002] PCR technology is one of the most important and most commonly used technologies in today's medical and biological research, and almost all molecular biology laboratories need to perform PCR reaction operations. In experiments, it is generally necessary to manually open the caps of PCR tubes one by one. Since the volume is small, the cap and the tube body are tightly matched, it is difficult to open, and the edge area of the cap is small, the force area is small, it is laborious to manually open the cap, and the fingers are easily swollen and painful after multiple openings, which is inconvenient to use. Therefore, it is of great significance to propose an auxiliary device or an easy-to-open method for PCR tube uncapping to improve the efficiency of PCR technology operation.

[0003] To solve the above technical problems, Chinese utility model patent CN220012088U discloses a PCR tube opener convenient to hold, which comprises a first fixed block, a first fixed plate is fixedly installed at the side end of the first fixed block, a sliding block is slidably installed on the outer surface of the first fixed block, a second groove is formed in the inside of the sliding block, a third fixed plate is fixedly installed at the upper end of the sliding block, two springs are fixedly installed at the side end of the third fixed plate, and a third fixed block is fixedly installed at the lower end of the sliding block. When the user slowly releases the third fixed plate, the third fixed plate will approach the first fixed plate under the cooperation of the spring and the second fixed plate. At this time, the third fixed block and the second fixed plate installed below will squeeze the PCR tube cap. At this time, the user holds the handle with one hand and holds the PCR tube with the other hand, and then presses the hand holding the handle downward to open the PCR tube cap. In addition, Chinese utility model patent CN213112463U discloses a PCR tube uncapping device, which comprises a rotating shaft, an upward turning device and a lower fixing device. The upward turning device comprises a plurality of split plates, the bottom edge of the split plate is connected with a first sleeve which is sleeved on the rotating shaft, the inner side of the split plate is vertically connected with a transition plate, the end of one of the two adjacent transition plates is vertically connected with a sliding groove plate, the sliding groove plate is provided with a sliding groove, the end of the other of the two adjacent transition plates is connected with a plug rod, and the plug rod penetrates through the sliding groove. The split plate is provided with an uncapping groove. The lower fixing device comprises a fixed plate, one end of the fixed plate is provided with a rectangular groove, the width of the rectangular groove is not less than the width of the first sleeve, the fixed plate on both sides of the rectangular groove is respectively connected with a second sleeve, the second sleeve is sleeved on the rotating shaft, and the two adjacent second sleeves are located between the two first sleeves. The other end of the fixed plate is provided with an open groove. The utility model can be used for PCR tubes with various spacings, and is convenient to adjust the spacing and save time and effort.

[0004] The above patent technologies all greatly reduce the difficulty of opening the PCR cover by designing a special cover opening device, but still have the following technical problems or improvement directions: (1) CN220012088U can only open a single PCR tube with one cap opening operation, and cannot realize batch cap opening operation; (2) CN213112463U can adjust the distance, but the adjustment method cannot guarantee that each cap opening point is adjusted at the same distance at the same time; resulting in inconvenient distance adjustment; (3) CN213112463U cap opening operation is only suitable for a single PCR tube diameter, and cannot adapt to cap opening diameter adjustment for different tube diameters, resulting in limited application range. Utility model content

[0005] In view of the above defects or improvement needs of the prior art, the utility model provides a PCR tube cover opening device suitable for multiple tube diameters. The equal distance and simultaneous adjustment of the cap opening point distance is realized by adopting a cross link mechanism, and a chute type interference assembly is arranged below the cross link mechanism to prevent the structure from being stuck due to the up and down movement of the link mechanism during movement; by adopting a rotating clamping structure, different caliber pry cover tubes arranged in an array are combined to meet the cap opening needs of different batches of PCR tubes with different diameters, and the technical problem of limited application range caused by the cap opening operation only suitable for a single PCR tube diameter and unable to adapt to cap opening diameter adjustment for different tube diameters in the prior art is solved.

[0006] In order to achieve the above purpose, a PCR tube cover opening device suitable for multiple tube diameters comprises:

[0007] A main housing, a cap opening execution unit arranged on the lower surface of the main housing, and a pry head switching unit for switching the pry head model in the cap opening execution unit;

[0008] The cap opening execution unit comprises a fixed link horizontally fixed to the lower segment of the main housing, a horizontal sliding block horizontally and slidingly installed on the fixed link, a flat circular U-shaped connecting groove sleeved on the lower extending end of the horizontal sliding block, a first horizontal connecting shaft coaxially and fixedly connected with the center axis direction of the circular surface of the U-shaped connecting groove and rotationally connected with the lower end of the horizontal sliding block; pry cover tubes are arranged in an equidistant annular array on the side surface below the U-shaped connecting groove; and the first horizontal connecting shaft is a telescopic rod;

[0009] The pry head switching unit switches the pry cover tube suitable for the PCR tube diameter to be directly below the U-shaped connecting groove, inserts the side edge outer convex part into the pry cover tube port, and pry the main housing upward to open the tube cap.

[0010] Preferably, the pry head switching unit comprises:

[0011] Horizontal sliding hole is horizontally arranged in the side wall of the U-shaped connecting groove, T-shaped clamp is horizontally slid in the horizontal sliding hole, and positioning clamping hole is arranged on the lower end side surface of the horizontal sliding block.

[0012] Preferably, further comprising:

[0013] Preferably, further comprising:

[0014] Preferably, the spacing adjustment transmission unit comprises:

[0015] Cross-link mechanism is horizontally interconnected and mounted in the main shell, pull-back spring is horizontally connected to adjacent hinge points in the cross-link mechanism, sliding block is arranged at each hinge point below the cross-link mechanism, and anti-interference sliding groove is arranged on the upper end of the horizontal sliding block.

[0016] Preferably, the spacing adjustment trigger unit comprises:

[0017] Extension block is arranged on the upper surface of the main shell, vertical sliding hole is vertically arranged in the center of the extension block, pull T-shaped handle is mounted in the inner cavity of the extension block and vertically slidably connected with the vertical sliding hole, and reset spring is mounted on the upper surface of the pull T-shaped handle and the top surface of the inner cavity of the extension block.

[0018] Preferably, the included angle between adjacent center axes of the pry cover pipes is greater than 45°.

[0019] Overall, compared with the prior art, the above technical scheme conceived by the utility model can achieve the following beneficial effects:

[0020] (1) The PCR tube opening cover device suitable for multiple pipe diameters of the utility model realizes equal-distance adjustment of cap opening point spacing by adopting a cross-link mechanism, and a sliding groove type interference assembly is arranged below the cross-link mechanism to prevent the structure from being stuck due to up-down movement during movement of the connecting rod mechanism.

[0021] (2) The PCR tube opening cover device suitable for multiple pipe diameters of the utility model adopts a rotating clamping structure, combines multiple arrayed pry cover pipes with different diameters, meets the cap opening requirements of different batches of PCR pipes with different diameters, solves the technical problem that the cap opening operation in the prior art is only suitable for a single PCR pipe diameter and cannot adapt to cap opening diameters of different pipe diameters, and limits the application range. BRIEF DESCRIPTION OF DRAWINGS

[0022] Figure 1 It is the overall structure schematic view of a multi-pipe diameter applicable PCR tube opening device for the embodiment of the utility model;

[0023] Figure 2 It is the pry head conversion unit assembly structure schematic view of a multi-pipe diameter applicable PCR tube opening device for the embodiment of the utility model;

[0024] Figure 3 It is the pry head conversion unit assembly structure schematic view of a multi-pipe diameter applicable PCR tube opening device for the embodiment of the utility model;

[0025] Figure 4 It is the partial enlarged view A of a multi-pipe diameter applicable PCR tube opening device for the embodiment of the utility model;

[0026] Figure 5 It is the PCR tube structure schematic view of a multi-pipe diameter applicable PCR tube opening device for the embodiment of the utility model;

[0027] In all the drawings, same reference signs represent same technical features, specifically: 1-main shell, 2-distance adjustment trigger unit, 201-protruding block, 202-vertical sliding hole, 203-lift T-shaped handle, 204-return spring, 3-distance adjustment transmission unit, 300-cross link mechanism, 301-back pull spring, 4-cap opening execution unit, 401-horizontal sliding block, 402-anti-interference sliding groove, 403-sliding block, 404-first horizontal connecting shaft, 405-U-shaped connecting groove, 406-pry cap tube, 407-rotary connecting hole, 408-fixed connecting rod, 5-pry head conversion unit, 501-T-shaped clamp, 502-positioning clamping hole, 503-horizontal sliding hole, 6-cap body, 601-lateral edge outer convex part. DETAILED DESCRIPTION

[0028] In the description of the present application, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise" and the like is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the utility model.

[0029] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0030] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0031] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only for explaining the present utility model and are not intended to limit the present utility model. Furthermore, the technical features involved in the various embodiments of the present utility model described below can be combined with each other as long as they do not conflict with each other.

[0032] like Figures 1 to 5 As shown in this embodiment of the invention, the PCR tube opening device suitable for multiple tube diameters includes:

[0033] Main housing 1, cap opening execution unit 4 disposed on the lower inner surface of the main housing 1, and pry head conversion unit 5 for switching the pry head model in the cap opening execution unit 4;

[0034] The cap-opening execution unit 4 includes a fixed connecting rod 408 horizontally fixed to the lower section of the main housing 1, a horizontal slider 401 horizontally slidably mounted on the fixed connecting rod 408, a flat, round U-shaped connecting groove 405 fitted onto the lower protruding end of the horizontal slider 401, a first horizontal connecting shaft 404 coaxially fixedly connected to the central axis of the circular surface of the U-shaped connecting groove 405 and rotatably connected to the lower end rotatable connecting hole 407 of the horizontal slider 401; and pry tubes 406 arranged in an equidistant annular array on the lower side annular surface of the U-shaped connecting groove 405; the first horizontal connecting shaft 404 is a telescopic rod.

[0035] Using the pry head conversion unit 5, switch the pry cap tube 406, which is adapted to the PCR tube diameter, to the U-shaped connecting groove 405 directly below it. Insert the side protrusion 601 into the opening of the pry cap tube 406 and pry up the main housing 1 to open the tube cap.

[0036] As Figures 2 to 4 shown in the utility model embodiment, the pry head conversion unit 5, comprising:

[0037] The horizontal slide hole 503 is horizontally arranged in the side wall of the U-shaped connecting groove 405, the T-shaped clamp 501 is horizontally slid in the horizontal slide hole 503, the positioning clamping hole 502 is oppositely arranged in the lower end side surface of the horizontal slide block 401, and the front end of the T-shaped clamp 501 is inserted and clamped into the positioning clamping hole 502.

[0038] As Figure 1 and Figure 4 shown in the utility model embodiment, the PCR tube opening device suitable for multiple pipe diameters comprises:

[0039] The spacing adjustment transmission unit 3 is used for adjusting the adjacent spacing of a plurality of horizontal slide blocks 401, and the spacing adjustment trigger unit 2 is used for manually controlling the adjustment amount of the spacing adjustment transmission unit 3.

[0040] As Figure 1 and Figure 4 shown in the utility model embodiment, the spacing adjustment transmission unit 3 comprises:

[0041] The cross-link mechanism 300 is horizontally interconnected and installed in the main shell 1, the back-pulling spring 301 is horizontally connected to the adjacent hinge points in the middle of the cross-link mechanism 300, the slide block 403 is arranged at each hinge point below the cross-link mechanism 300, and the anti-interference sliding groove 402 is arranged at the upper end of the horizontal slide block 401; the slide block 403 and the anti-interference sliding groove 402 are vertically and slidably connected.

[0042] As Figure 1 and Figure 4 shown in the utility model embodiment, the spacing adjustment trigger unit 2 comprises:

[0043] The extension block 201 is arranged on the upper surface of the main shell 1, the vertical slide hole 202 is vertically arranged in the center of the extension block 201, the pull T-shaped handle 203 is installed in the inner cavity of the extension block 201 and vertically and slidably connected with the vertical slide hole 202, and the reset spring 204 is installed on the upper surface of the pull T-shaped handle 203 and the top surface of the inner cavity of the extension block 201; the lower end of the pull T-shaped handle 203 is rotationally connected with the upper hinge point of the cross-link mechanism 300.

[0044] As Figure 2 and Figure 3 shown in the utility model embodiment, the included angle between the center axes of adjacent pry cover tubes 406 is greater than 45°.

[0045] The utility model discloses a working principle: first, the PCR tube uncapping preparation stage is carried out, and the PCR tube is equidistantly inserted into the test tube support, and the outer convex part 601 of the side edge of the PCR tube is rotated to the front; then, according to the current batch PCR tube diameter, the pry cap tube 406 suitable for use is adjusted, specifically, the T-shaped clamp 501 is manually pulled out, and the U-shaped connecting groove 405 is rotated, under the action of the first horizontal connecting shaft 404, the other U-shaped connecting grooves 405 are synchronously rotated, so that the pry cap tube 406 suitable for use is rotated to the position directly below the device, then the T-shaped clamp 501 is pressed inward, so as to be clamped into the positioning clamping hole 502, and the locking is completed; then, according to the PCR tube spacing, the pry cap tube 406 spacing is adjusted, specifically, the T-shaped handle 203 is manually lifted and pulled, so as to drive the cross-link mechanism 300 to produce deformation, so that the spacing between the adjacent hinge points below changes, and then the pry cap tube 406 spacing is adjusted; then, the outer convex part 601 of the side edge is inserted into the pry cap tube 406 pipe opening and the main shell 1 is pried upward, and the batch cap opening is realized.

[0046] In the utility model embodiment, through the cross-link mechanism, the equidistant adjustment of the cap opening point spacing is realized, and the slide groove type interference assembly is arranged below, so that the technical problem of structure jamming caused by the up-down movement of the connecting rod mechanism during movement is prevented.

[0047] In addition, by adopting the rotating clamping structure, the different caliber pry cap tubes arranged in an array are combined, the cap opening requirements of different batches of PCR tubes with different diameters are met, the technical problem that the cap opening operation in the prior art is only suitable for a single PCR tube diameter and cannot realize the cap opening caliber adaptive adjustment of different tube diameters, resulting in limited application range is solved.

[0048] The above is only the preferred embodiment of the present application, and does not limit the present application, and any modification, equivalent replacement and improvement made within the spirit and principle of the present application should be included in the protection scope of the present application. The above is only the preferred embodiment of the present application, and it should be pointed out that, for ordinary skilled in the art, without departing from the technical principles of the present application, a plurality of improvements and modifications can be made, and these improvements and modifications should be regarded as the protection scope of the present application.

Claims

1. A PCR tube opening device suitable for multiple tube diameters, characterized in that, It includes: The main shell (1), the cap opening execution unit (4) arranged on the lower surface of the main shell (1), and the pry head switching unit (5) for switching the pry head type in the cap opening execution unit (4); The cap opening execution unit (4) comprises a fixed connecting rod (408) horizontally fixed to the lower section of the main shell (1), a horizontal sliding block (401) horizontally slidingly installed on the fixed connecting rod (408), a flat round U-shaped connecting groove (405) sleeved on the lower extension end of the horizontal sliding block (401), a first horizontal connecting shaft (404) coaxially fixedly connected with the center axis direction of the round surface of the U-shaped connecting groove (405) and rotationally connected with the lower end rotationally connected hole (407) of the horizontal sliding block (401); the pry cover pipe (406) is equidistantly arranged in the side ring surface below the U-shaped connecting groove (405); and the first horizontal connecting shaft (404) is a telescopic rod. The pry cover pipe (406) suitable for the diameter of the PCR tube is switched below the U-shaped connecting groove (405) through the pry head switching unit (5), the side edge outer protrusion (601) is inserted into the pipe opening of the pry cover pipe (406), and the main shell (1) is pryed upward to open the tube cap. The pry head switching unit (5) comprises a horizontal sliding hole (503) horizontally penetrating the side wall of the U-shaped connecting groove (405), a T-shaped clamp (501) horizontally sliding in the horizontal sliding hole (503), and a positioning clamp hole (502) oppositely arranged on the side surface of the lower end of the horizontal sliding block (401); the front end of the T-shaped clamp (501) is inserted and clamped with the positioning clamp hole (502).

2. The PCR tube uncap device of claim 1, wherein, It also includes: The pitch adjustment transmission unit (3) for equidistantly adjusting the adjacent pitch of a plurality of horizontal sliding blocks (401), and the pitch adjustment trigger unit (2) for manually controlling the adjustment amount of the pitch adjustment transmission unit (3).

3. The PCR tube uncap device of claim 2, wherein, The pitch adjustment transmission unit (3) comprises: A cross-link mechanism (300) horizontally interconnectedly installed in the main shell (1), a back-pulling spring (301) horizontally connected to the adjacent hinge points in the middle of the cross-link mechanism (300), a sliding block (403) arranged at each hinge point below the cross-link mechanism (300), and an anti-interference sliding groove (402) arranged on the upper end of the horizontal sliding block (401); the sliding block (403) is vertically slidingly connected with the anti-interference sliding groove (402).

4. The PCR tube uncap device of claim 3, wherein, The pitch adjustment trigger unit (2) comprises: An extension block (201) arranged on the upper surface of the main shell (1), a vertical sliding hole (202) vertically arranged in the center of the extension block (201), a pull T-shaped handle (203) installed in the inner cavity of the extension block (201) and vertically slidingly connected with the vertical sliding hole (202), and a reset spring (204) installed on the upper surface of the pull T-shaped handle (203) and the top surface of the inner cavity of the extension block (201); the lower end of the pull T-shaped handle (203) is rotationally connected with the upper hinge point of the cross-link mechanism (300).

5. The PCR tube uncap device of any one of claims 1-4, wherein: The included angle between the center axes of adjacent pry cover pipes (406) is greater than 45°.

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