96-well plate device capable of preventing wrong sample adding

Abstract

The utility model relates to the technical field of test instruments, and aims to solve the technical problems that only longitudinal sample adding can be performed, but transverse sample adding cannot be performed, and samples cannot be distinguished when being added into a plurality of hole sites in the longitudinal or transverse direction. In order to solve the technical problem, the utility model provides the 96-well plate device capable of preventing wrong sample adding. The utility model comprises: a base; a plurality of lamp strips are arranged on the base; the 96-well plate is installed in the base, a plurality of hole sites distributed in a matrix mode are formed in the 96-well plate, and the hole sites and the lamp strips are arranged in a one-to-one correspondence mode up and down; the mistaken adding prevention cover plate is detachably connected to the top of the base; a plurality of through holes are formed in the mistaken-adding-preventing cover plate, and the through holes and the hole sites are arranged in a one-to-one correspondence mode up and down; an easily-broken hole cover is connected to the through hole; the sealing cover plate is connected to the top of the base in an openable and closable mode. The lamp strip disclosed by the utility model is used for distinguishing rows and columns, and the easily-broken hole cover can be used for distinguishing whether samples are added into a plurality of hole sites in a certain row or column, so that wrong adding and missing adding of the samples can be avoided, and the experiment precision and efficiency are improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to test apparatus technical field especially is a kind of 96 well plate device of preventing wrong sample addition. BACKGROUND

[0002] 96 well plate is a kind of experimental tool widely used in biology, chemistry and medical experiment, it is usually composed of 12 rows 8 columns of holes. Its structure is suitable for a variety of high-throughput screening experiments, PCR reaction, ELISA detection etc. With the diversification of experimental demand, 96 well plate is widely used in drug research and development, gene analysis and clinical diagnosis etc.

[0003] But 96 well plate is due to hole position numerous and similar, it is easy to appear wrong sample addition when operating. This not only wastes sample, but also can lead to experimental result distortion, data inaccuracy, and then influence the reliability of experimental conclusion and the effectiveness of subsequent research.

[0004] In the Chinese patent with publication number CN107488589A, a 96 well plate sample addition marker is disclosed, which includes an upper opening seat body, a transparent identification cover plate and a lamp strip aligned with each sample addition hole. The device lights up the lamp strip to mark the sample addition hole that has been added by the button on the identification cover plate, and turns off all lamp strips through master switch after a column of sample addition holes is added, and moves horizontally to the next column of sample addition holes for addition, to avoid sample addition error, and does not miss or repeat sample addition. But it can only be added vertically and cannot be added horizontally, and multiple hole positions cannot be distinguished when adding vertically or horizontally. UTILITY MODEL CONTENT

[0005] Therefore, the utility model solves the technical problems in the prior art.

[0006] To solve the above technical problems, the utility model provides a 96 well plate device for preventing wrong sample addition, which comprises:

[0007] The base is a top-opening box structure, and a plurality of lamp strips are arranged on the base.

[0008] The 96 well plate is installed in the base, and a plurality of hole positions arranged in a matrix are arranged on the 96 well plate, and the hole positions are arranged one by one below the lamp strips.

[0009] The anti-wrong sample addition cover plate is detachably connected to the top of the base, a plurality of through holes are arranged on the anti-wrong sample addition cover plate, the through holes are arranged one by one below the hole positions, and a breakable hole cover is connected to the through hole.

[0010] The sealing cover plate is openably and closably connected to the top of the base.

[0011] In one embodiment of the utility model, the breakable cover includes a connecting part and a separating part, the connecting part is connected with the inner wall of the through hole, and the separating part is connected with the inner wall of the through hole through a plurality of connecting strips.

[0012] In one embodiment of the utility model, the connecting part is arranged towards the right side of the technician.

[0013] In one embodiment of the utility model, the anti-misplacement cover plate is disposable.

[0014] In one embodiment of the utility model, along the length direction or the width direction of the anti-misplacement cover plate, buckles are arranged on both sides of the anti-misplacement cover plate; the buckles are formed by protruding outward from the side wall of the anti-misplacement cover plate, at least one side of the position where the buckle is connected with the anti-misplacement cover plate is provided with a groove formed by being recessed inward; the top of the base is provided with a first clamping groove corresponding to the buckle; and the groove is clamped in the first clamping groove.

[0015] In one embodiment of the utility model, along the length direction or the width direction of the anti-misplacement cover plate, handles are arranged on both sides of the anti-misplacement cover plate; the top of the base is provided with a second clamping groove corresponding to the handle; and the handle is clamped in the second clamping groove and extends out of the base.

[0016] In one embodiment of the utility model, the application further includes a control end and an adjusting button arranged on the outer wall of one side of the base, the adjusting button is electrically connected with the control end, and the lamp strip is electrically connected with the control end.

[0017] In one embodiment of the utility model, the anti-misplacement cover plate is made of transparent material.

[0018] In one embodiment of the utility model, the anti-misplacement cover plate is provided with column direction marks and horizontal direction marks.

[0019] In one embodiment of the utility model, the column direction marks and the horizontal direction marks are different.

[0020] The above technical solution of the utility model has the following advantages compared with the prior art:

[0021] The 96-well plate device for preventing incorrect sample addition described in this utility model is equipped with an LED strip. During sample addition, the LEDs illuminate to indicate the correct row or column direction, thus preventing incorrect sample addition. This application also includes an error-prevention cover plate with a puncture-proof cap on its through-hole. This allows for identification of whether multiple wells in a row or column have been sampled by checking if the cap has been punctured (caps indicating sample addition are punctured, while caps indicating no sample addition are intact). This effectively prevents duplicate, missed, or incorrect sample addition in a row or column. Therefore, the combination of the LED strip and the puncture-proof cap can prevent incorrect or missed sample addition, reduce operational errors, and improve experimental accuracy and efficiency. Furthermore, the LED strip can be illuminated horizontally or vertically, allowing technicians to flexibly choose the light indication for the sample addition sequence (row or column) according to their sample addition habits, facilitating operation. Attached Figure Description

[0022] To make the content of this utility model easier to understand, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings, wherein:

[0023] Figure 1 This is a schematic diagram of the structure of a 96-well plate device for preventing incorrect sample addition in a preferred embodiment of this utility model;

[0024] Figure 2 yes Figure 1 A schematic diagram showing the connection between the base and the anti-error cover plate in a 96-hole plate device for preventing incorrect sample addition;

[0025] Figure 3 yes Figure 1 A schematic diagram of the anti-mistake cover plate in the 96-hole plate anti-mistake sample device;

[0026] Figure 4 yes Figure 1 A schematic diagram of the base structure in the 96-hole plate device for preventing incorrect sample addition;

[0027] Figure 5 yes Figure 1 A schematic diagram of the easily broken orifice cap being punctured during sample addition in a 96-well plate device designed to prevent incorrect sample addition;

[0028] Instruction manual illustrations and markings: 100, base; 110, LED strip; 120, first slot; 130, second slot;

[0029] 200, 96-hole plate; 210, hole position;

[0030] 300. Anti-misfill cover; 310. Through hole; 320. Easily breakable cover; 321. Connecting part; 322. Separating part; 330. Buckle; 331. Groove; 340. Handle; 350. Column orientation mark; 360. Horizontal orientation mark;

[0031] 400, sealing cover plate;

[0032] 500, adjusting button;

[0033] 600, pipette;

[0034] 700, power cord. DETAILED DESCRIPTION

[0035] The utility model will be further explained in connection with the drawings and specific embodiments, so that the person skilled in the art can better understand the utility model and can be implemented, but the embodiment is not as the limitation of the utility model.

[0036] In the actual application process, the operation habits of different technicians are different (some are used to adding samples column by column, and some are used to adding samples row by row). For example, in the process of adding samples column by column, there are often adjacent two columns of adding mistakes, or the hole position of the same column is missed, or the same hole position is repeatedly added. In some comparative examples, only one column (or one row) can be distinguished, and multiple hole positions in the same column (or row) cannot be distinguished. In order to solve the problem, the following improvements are made in the present application.

[0037] Referring to Figures 1-5 The utility model embodiment provides a kind of 96 well plate device of preventing adding wrong sample, comprising:

[0038] Base 100, the box structure of top opening;Base 100 is equipped with multiple lamp strips 110;

[0039] 96 well plate 200, is installed in base 100, and 96 well plate 200 is equipped with multiple hole positions 210 in matrix arrangement, and hole position 210 is set one by one with lamp strip 110 up and down;

[0040] Anti-mistake cover plate 300, detachably connected in the top of base 100;Anti-mistake cover plate 300 is equipped with multiple through holes 310, and through hole 310 is set one by one with hole position 210 up and down;Through hole 310 is connected with breakable hole cover 320;Anti-mistake cover plate 300 is disposable, and it is sterile material quality.Disposable design avoids cross contamination, and it is convenient to clean and replace.

[0041] Sealing cover plate 400, openable and closeable connection in the top of base 100.

[0042] Specifically, the embodiment is provided with the light strip 110, so that the correct row or column direction can be indicated by lighting during the sample adding process, thereby avoiding adding the sample to the wrong row or column. The application is also provided with the anti-addition error cover plate 300, and the through hole 310 of the anti-addition error cover plate 300 is provided with the breakable hole cover 320, so that whether the plurality of hole positions 210 in the corresponding row or column have been added (the breakable hole cover 320 that has been added with the sample is in the broken state, and the breakable hole cover 320 that has not been added with the sample is in the intact state) can be distinguished by whether the breakable hole cover 320 is broken in the corresponding row or column, thereby effectively avoiding that the plurality of hole positions 210 in a certain row or column repeatedly add, miss, or add the sample. As can be seen, the light strip 110 is used to indicate the row or column direction of the sample adding, and whether the hole positions 210 in the row or column have been added is distinguished by the breakable hole cover 320, so that the sample adding error and the missing sample adding can be avoided, the operation error can be reduced, the experimental precision and efficiency can be improved. In addition, the light strip 110 can be selectively lit in the horizontal or vertical direction, the light indication of the sample adding sequence (row or column) can be flexibly selected according to the sample adding habit of the technician, and the operation is facilitated.

[0043] Further, the breakable hole cover 320 includes a connecting portion 321 and a separation portion 322, the connecting portion 321 is connected with the inner wall of the through hole 310, and the separation portion 322 is connected with the inner wall of the through hole 310 through a plurality of connecting strips, and the plurality of connecting strips are arranged at intervals along the circumference of the through hole 310. Specifically, the connecting portion 321 of the breakable hole cover 320 of the embodiment is connected with the through hole 310, and the separation portion 322 is connected with the through hole 310 through a plurality of connecting strips, that is, a large part of the side wall of the separation portion 322 is not connected with the through hole 310. In this way, a gap through which the pipette 600 can pass is reserved for the pipette 600 at the separation portion 322, so that the pipette 600 can easily break the breakable hole cover 320.

[0044] Further, the connecting portion 321 is arranged towards the right side of the technician. Specifically, since the posture of the technician during the sample adding is generally to tilt the top of the pipette 600 to the right, and the gun head of the pipette 600 is directed to the left side wall to pour the liquid into the container, the application arranges the connecting portion 321 to the right side and arranges the separation portion 322 to the left side, so that the technician can easily break the breakable hole cover 320 by tilting the pipette 600 outward.

[0045] Further, along the length direction or the width direction of the anti-misplacement cover plate 300, buckles 330 are arranged on both sides of the anti-misplacement cover plate 300; the buckles 330 are formed by protruding outward from the side wall of the anti-misplacement cover plate 300, at least one side of the position where the buckle 330 is connected with the anti-misplacement cover plate 300 is provided with a groove 331 formed by recessing inward; the top of the base 100 is respectively provided with a first clamping groove 120 corresponding to the buckle 330; the groove 331 is clamped in the first clamping groove 120. Specifically, the abutment of the buckle 330 and the first clamping groove 120 in the embodiment is adopted to avoid the back-and-forth movement of the anti-misplacement cover plate 300, so as to realize the quick connection and disassembly of the anti-misplacement cover plate 300 and the base 100, which is simple in structure and convenient to use. The anti-misplacement cover plate 300 is closely combined with the base 100, so as to ensure the stability and safety.

[0046] Further, along the length direction or the width direction of the anti-misplacement cover plate 300, handles 340 are arranged on both sides of the anti-misplacement cover plate 300; the top of the base 100 is respectively provided with a second clamping groove 130 corresponding to the handle 340, the handle 340 is arranged in the second clamping groove 130 and extends out of the base 100. Specifically, the handle 340 is arranged in the embodiment, so as to facilitate the user to hold the handle 340 to clamp the anti-misplacement cover plate 300 on the base 100 or disassemble the anti-misplacement cover plate 300 from the base 100, which is more convenient and fast to use. In some embodiments, the handle 340 and the buckle 330 are arranged on different sides of the base 100.

[0047] Further, the application also includes a control end and an adjusting button 500 arranged on one side of the outer wall of the base 100, the adjusting button 500 is electrically connected with the control end, and the lamp strip 110 is electrically connected with the control end. Specifically, the opening sequence of the lamp strip 110 can be controlled through the adjusting button 500 in the embodiment, which is more convenient for the technician to control. In some embodiments, four keys of up, down, left and right are arranged on the adjusting button 500, so as to flexibly adjust the on-off state of the corresponding row or column of the lamp strip 110. The lamp strip 110 is connected with the power supply through a power line 700.

[0048] Further, the anti-misplacement cover plate 300 is made of transparent material. Specifically, the anti-misplacement cover plate 300 in the embodiment is made of transparent material, so as to facilitate the observation of whether the lamp strip 110 is lighted.

[0049] Further, the anti-misplacement cover plate 300 is provided with column direction identifiers 350 and horizontal direction identifiers 360. Specifically, the column direction identifiers 350 and the horizontal direction identifiers 360 are adopted to number each hole position 210 in the embodiment, so as to distinguish the hole positions 210.

[0050] Further, the column direction identifiers 350 and the horizontal direction identifiers 360 are different. For example, one of the column direction identifiers 350 and the horizontal direction identifiers 360 adopts numbers, and the other adopts letters. Specifically, this is more convenient for distinguishing the rows and columns.

[0051] When the technician connects the power supply line 700 to the power supply, the application is started. The technician adjusts the light strips 110 (i.e. a row or a column of light strips 110 is lit) according to the sample adding habits and sample adding needs. For example, the technician needs to add samples to all the hole sites 210 in A2 to D9. Taking the row-by-row adding as an example (i.e. adding from A2 to A9, and then adding from A row to D row), the specific steps are as follows:

[0052] S1: First, the technician can adjust the light strip 110 of A row to be lit by adjusting the button 500. At this time, the technician can be prompted to add samples in this row.

[0053] S2: Then the technician uses the gun head of the pipette 600 to gently tap the corresponding breakable hole cover 320 of the hole site 210 from A2 to A9 in A row, so as to add samples in sequence.

[0054] S3: After the sample adding in the row is completed, the technician presses the button downward to adjust the light strip 110 of B row to be lit, so as to repeat S1 to S2 until the sample adding of the corresponding multiple hole sites 210 is completed.

[0055] Obviously, the above embodiments are only examples for clear illustration, and are not a limitation on the embodiments. For those skilled in the art, other different forms of changes or variations can be made on the basis of the above description. Here, it is not necessary and impossible to enumerate all the embodiments. The obvious changes or variations derived therefrom are still within the protection scope of the present application.

Claims

1. A misaddition prevention 96-well plate device, characterized by: The utility model relates to a kind of laboratory workbench, including: Base, the box structure of top opening;Multiple lamp strips are provided on the base; 96-hole plate, installed in the base, multiple holes are provided in matrix arrangement on the 96-hole plate, and the hole is set one by one with the lamp strip up and down; Anti-misplacement cover plate, detachably connected at the top of the base;Multiple through holes are provided on the anti-misplacement cover plate, and the through hole is set one by one with the hole up and down;Frangible hole cover is connected on the through hole; Sealing cover plate, openable and closeable connection is established at the top of the base.

2. The anti-skewing 96-well plate device of claim 1, wherein: The frangible hole cover includes connecting part and separation part, the connecting part is connected with the inner wall of the through hole;The separation part is connected with the inner wall of the through hole by multiple connecting strips, and the multiple connecting strips are spaced along the circumference of the through hole.

3. The anti-skewing 96-well plate device of claim 2, wherein: The connecting part is set to the right side of technician.

4. The anti-skewing 96-well plate device of claim 1, wherein: The anti-misplacement cover plate is disposable.

5. The anti-skewing 96-well plate device of claim 1, wherein: Along the length direction of the anti-misplacement cover plate, both sides of the anti-misplacement cover plate are provided with buckle;The buckle is formed by protruding outward from the side wall of the anti-misplacement cover plate, and at least one side of the position where the buckle is connected with the anti-misplacement cover plate is provided with recess formed by recessing inward;Both sides of the top of the base are respectively provided with first clamping groove corresponding to the buckle;Groove is clamped in the first clamping groove.

6. The anti-skewing 96-well plate device of claim 5, wherein: Along the width direction of the anti-misplacement cover plate, both sides of the anti-misplacement cover plate are provided with handle;Both sides of the top of the base are respectively provided with second clamping groove corresponding to the handle, and the handle is arranged in the second clamping groove and extends outside the base.

7. The anti-skewing 96-well plate device of claim 1, wherein: It further includes control end and adjustment button arranged on the side outer wall of the base, the adjustment button is electrically connected with the control end, and the lamp strip is electrically connected with the control end.

8. The anti-skewing 96-well plate device of claim 1, wherein: The anti-misplacement cover plate adopts transparent material.

9. The anti-skewing 96-well plate device of claim 1, wherein: The anti-misplacement cover plate is provided with column direction mark and horizontal direction mark.

10. The anti-skewing 96-well plate device of claim 9, wherein: The column direction mark and the horizontal direction mark are different.

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