Mouse skin cell collection brush
By designing a combination of sliding and rotating blocks, the brush length of the mouse skin cell collection brush can be adjusted and quickly assembled and disassembled, solving the problems of low efficiency and insufficient accuracy caused by fixed brush length in existing technologies, and improving the applicability and efficiency of collection.
Patent Information
- Application Number
- CN202422988707.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-05
- Publication Date
- 2026-01-27
- Estimated Expiration
- 2034-12-05
AI Technical Summary
Existing mouse skin cell collection brushes lack convenient brush length adjustment, resulting in low efficiency in different collection scenarios and difficulty in precise operation in confined areas, affecting the quality and efficiency of cell samples.
A mouse skin cell collection brush was designed. Through a combination of sliding and rotating blocks, the brush length can be adjusted and quickly disassembled. Combined with limiting and disassembly components, the brush length can be adjusted and replaced as needed.
This improved the applicability and efficiency of cell collection, ensured precise operation at different sites, reduced harm to mice, and enhanced the scientific rigor and convenience of cell collection.
Smart Images
Figure CN223831129U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of cell collection technology, and in particular to a brush for collecting mouse skin cells. Background Technology
[0002] Mouse skin cell collection brushes have wide applications in medical research. In skin disease research, collecting mouse skin cells allows for the establishment of disease models to study disease mechanisms, pathological changes, and the effects of drug treatments. In tissue engineering and regenerative medicine, the collected skin cells can be used to culture skin tissue, providing a cell source for the repair and regeneration of skin damage.
[0003] The cell collection brush mainly consists of a brush head and a brush handle. When the collection brush comes into contact with the tissue surface where the target cells are located (such as skin, mucous membranes, etc.), by gently brushing back and forth and rotating, a moderate frictional force is generated between the bristles and the cells. This frictional force allows the cells that were originally attached to the tissue surface to detach from the original tissue and attach to the bristles, thus completing the collection.
[0004] Currently, some mouse cell collection brushes lack convenient brush length adjustment, forcing operators to use a fixed brush length when switching between different collection scenarios, resulting in low collection efficiency. Furthermore, when collecting cells from the relatively flat and large back skin of mice, a longer brush length increases the coverage area per brush stroke, thus more efficiently obtaining a sufficient number of cells. Conversely, when collecting skin cells from smaller, more delicate, and irregularly shaped areas such as around the ears, eyes, or limb joints, a shorter brush length is crucial. This allows operators to more precisely control the brush position, avoiding accidental contact with surrounding sensitive tissues and ensuring the accuracy of the collection operation and the quality of the cell sample. Therefore, this mouse skin cell collection brush is proposed to address these issues. Utility Model Content
[0005] To overcome the above shortcomings, this invention provides a mouse skin cell collection brush, which aims to improve the problem that existing brushes do not have a convenient brush length adjustment function.
[0006] To achieve the above objectives, the present invention adopts the following technical solution:
[0007] A mouse skin cell collection brush includes a housing, a sliding block slidably connected inside the housing, a rotating block rotatably connected to the rear end of the sliding block, a connecting post fixedly connected to the top end of the rotating block, a fixing block slidably connected inside the sliding block, a connecting post slidably connected to the outside of the housing, a brush fixedly connected to the front end of the fixing block, a limiting component for limiting the position on the outside of the connecting post, and a disassembly and assembly component for disassembly and assembly inside the rotating block.
[0008] As a further description of the above technical solution:
[0009] The limiting component includes a slider, the inside of which is slidably connected to the outside of the connecting post, the outside of which is threadedly connected to a threaded cap, the bottom end of which is fixedly connected to a limiting tooth, and the outside of which is provided with a limiting groove, the outside of which is slidably connected to the inside of the limiting groove.
[0010] As a further description of the above technical solution:
[0011] The outer surface of the housing has a sliding groove and a rotating groove.
[0012] As a further description of the above technical solution:
[0013] The housing has a storage hole inside, and a handle is fixedly connected to the rear end of the housing;
[0014] As a further description of the above technical solution:
[0015] The disassembly and assembly assembly includes a sliding tooth, the top of which is fixedly connected to a telescopic column. A telescopic spring is sleeved on the outside of the telescopic column, and the outside of the sliding tooth is slidably connected to the inside of the fixed block.
[0016] As a further description of the above technical solution:
[0017] The bottom end of the telescopic spring is fixedly connected to the top end of the sliding tooth, and the other end of the telescopic spring is fixedly connected to the inside of the rotating block.
[0018] As a further description of the above technical solution:
[0019] The top end of the telescopic column is fixedly connected to the inside of the rotating block, and the outside of the fixed block is rotatably connected to the inside of the rotating block;
[0020] As a further description of the above technical solution:
[0021] The brush is externally slidably connected to the inside of the housing, and the connecting post is externally slidably connected to the inside of the rotating groove.
[0022] This utility model has the following beneficial effects:
[0023] 1. In this invention, the length of the brush is adjusted by sliding the sliding block inside the storage hole. This ensures that when collecting cells from the eye, the brush can be adjusted to a shorter, more suitable length to gently and accurately contact the skin around the eye, avoiding unnecessary damage to the mouse's eyes due to an excessively long brush, while efficiently scraping off cells. When collecting cells from large areas such as the back, the brush can be extended to a suitable length to increase the coverage area of a single scraping and speed up the collection process. This greatly improves the applicability and efficiency of the collection work for different areas, making the entire collection process more scientific, convenient, and efficient.
[0024] 2. In this utility model, the method of disassembling and assembling the brush by rotating the block does not require additional complicated tools and can be completed by simple manual operation. In actual mouse skin cell collection work, whether the brush needs to be replaced due to wear and tear after long-term use, or different types of brushes need to be replaced for different collection needs (such as brushes with different bristle thickness and materials), the disassembly and assembly process can be completed quickly, which greatly saves time, improves work efficiency, and ensures the continuity and efficiency of collection work. Attached Figure Description
[0025] Figure 1 This is a three-dimensional schematic diagram of the mouse skin cell collection brush proposed in this utility model;
[0026] Figure 2 This is a schematic diagram of the fixing block of the mouse skin cell collection brush proposed in this utility model;
[0027] Figure 3 for Figure 2 Enlarged view of point A in the middle;
[0028] Figure 4 This is a schematic diagram of the connecting column of the mouse skin cell collection brush proposed in this utility model.
[0029] Legend:
[0030] 1. Housing; 2. Sliding block; 3. Rotating block; 4. Fixed block; 5. Sliding tooth; 6. Telescopic spring; 7. Telescopic column; 8. Connecting column; 9. Sliding block; 10. Limiting tooth; 11. Threaded cap; 12. Sliding groove; 13. Rotating groove; 14. Storage hole; 15. Limiting groove; 16. Brush; 17. Handle. Detailed Implementation
[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0032] Reference Figures 1 to 3 This utility model provides an embodiment of a mouse skin cell collection brush, comprising a housing 1. The housing 1 serves as the external support structure for the entire collection brush, protecting internal components and providing a mounting base for other components. A sliding block 2 is slidably connected inside the housing 1, allowing the sliding block 2 to slide smoothly within the housing 1, thereby changing the position of other connected components and adjusting related functions. A rotating block 3 is rotatably connected to the rear end of the sliding block 2, allowing the rotating block 3 to rotate around its connection point with the sliding block 2. This rotational characteristic facilitates subsequent operations and the assembly / disassembly of components. A connecting post 8 is fixedly connected to the top of the rotating block 3. The connecting post 8 plays a role in connecting and transmitting force in the entire structure, and also participates in some limiting functions, making it one of the key components ensuring the coordinated operation of all parts of the collection brush.
[0033] The sliding block 2 has a fixed block 4 internally connected to it. A brush 16 is fixedly connected to the front end of the fixed block 4. The fixed block 4, as the direct connection to the brush 16, moves the brush 16 along with the sliding block 2 and cooperates with components such as the rotating block 3 to switch the brush 16 between different states, such as extending or retracting. The brush 16 is a key component that directly contacts the mouse skin and is used to scrape and collect cells. Its material and bristle softness are designed according to the characteristics of mouse skin to effectively collect cells without harming the mouse. The connecting post 8 has a limiting component on its exterior. This component precisely limits the relative positions of the components, ensuring the stability of the collection brush during use and preventing unnecessary displacement that could affect the collection effect. The rotating block 3 has a disassembly / reassembly component inside, allowing the brush 16 to be easily and quickly replaced to meet different collection needs and extend the overall lifespan of the collection brush.
[0034] The limiting component includes a slider 9, which is internally slidably connected to the outside of the connecting post 8. The slider 9 can slide flexibly along the connecting post 8. The slider 9 is the key element in the limiting component that drives other related parts to achieve limiting and releasing actions. The bottom end of the slider 9 is fixedly connected to a limiting tooth 10. The limiting tooth 10 cooperates with the limiting groove 15 on the housing 1 to lock or release, thereby fixing and releasing the position of the sliding block 2, and thus affecting the position of the brush 16. The connecting post 8 is externally threaded with a threaded cap 11. By tightening and loosening the thread, the threaded cap 11 can apply or release pressure on the slider 9, thereby controlling the cooperation state between the limiting tooth 10 and the limiting groove 15, achieving precise control of the position of the brush 16. The housing 1 has a limiting groove 15 on its outside. The limiting groove 15 provides space for the limiting tooth 10 to lock in and slide out, and is a key structural part for realizing the limiting function.
[0035] The outer surface of the housing 1 has a sliding groove 12. This groove guides and limits the movement trajectory during the length adjustment of the brush 16 and the rotation of the rotating block 3, ensuring that the relevant operations are performed in a predetermined manner. The outer surface of the housing 1 also has a rotating groove 13, which provides suitable space for the rotation of the rotating block 3, ensuring smooth rotation and serving as an indispensable structural foundation for the assembly and disassembly of the brush 16. The inner surface of the housing 1 has a storage hole 14 for accommodating the brush 16. When the length of the brush 16 needs to be adjusted and stored, it slides into this space, facilitating changes in the overall length of the collection brush to adapt to different collection sites. A handle 17 is fixedly connected to the rear end of the housing 1. By holding the handle 17, the collector can easily operate the entire collection brush to scrape the surface of the mouse. The handle 17 is ergonomically designed for prolonged use, improving comfort and efficiency during collection.
[0036] Reference Figure 1 , Figure 2 and Figure 4 The disassembly and assembly components include a sliding tooth 5, which plays a crucial role in the entire disassembly and assembly process. The sliding tooth 5 has an ingeniously designed shape, typically with a certain bevel or curvature on one side, allowing it to slide more smoothly inside the fixed block 4 when compressed. A telescopic column 7 is fixedly connected to the top of the sliding tooth 5. The telescopic column 7 not only connects the sliding tooth 5 and the rotating block 3 but also possesses a certain degree of telescopic capability, adapting to changes in the position of the sliding tooth 5 under different conditions, ensuring structural stability and the transmission of force between components.
[0037] A telescopic spring 6 is fitted onto the outside of the telescopic column 7. The telescopic spring 6 is an important component for realizing the automatic reset of the sliding tooth 5 and providing appropriate squeezing force. The telescopic spring 6 is made of a metal material with good elasticity, such as high-quality stainless steel spring wire, and is processed by a special winding process to have a stable elastic coefficient. The bottom end of the telescopic spring 6 is fixedly connected to the top end of the sliding tooth 5, and the other end is fixedly connected to the inside of the rotating block 3. In the initial state, the telescopic spring 6 is in a naturally extended or slightly compressed state, providing a pre-tightening force for the sliding tooth 5 to embed into the fixed block 4, so that the sliding tooth 5 can be tightly locked inside the fixed block 4, ensuring a reliable connection between the brush 16 and the rotating block 3.
[0038] The external sliding connection of the sliding tooth 5 is inside the fixed block 4. The fixed block 4 has a slot or slide structure that matches the sliding tooth 5. The slot has high dimensional accuracy requirements, which must ensure that the sliding tooth 5 can slide smoothly in it, while avoiding excessive gaps that would cause the brush 16 to shake during normal use and affect the stability of the data collection. Moreover, the inner wall of the slot is smoothed to further reduce the friction when the sliding tooth 5 slides, making the entire assembly and disassembly operation smoother. The external rotatable connection of the fixed block 4 is inside the rotating block 3, which allows the fixed block 4 to rotate flexibly relative to the rotating block 3 and maintain good concentricity during rotation, avoiding wear between parts or affecting the accuracy of the assembly and disassembly operation due to eccentric rotation.
[0039] Working principle: When the collector needs to collect mouse cells using the collection brush, the brush 16 can be controlled by holding the handle 17 to scrape the surface of the mouse, thereby collecting cells. During the scraping process, the length of the brush 16 can be adjusted to facilitate collection of small areas such as the mouse's eyes. By manually rotating the threaded cap 11, the pressure on the slider 9 is released, causing the slider 9 to slide out of the limiting tooth 10 from the limiting groove 15, thus releasing the fixation of the sliding block 2. At this time, as needed, the slider 9 can be pulled to make the sliding block 2 move the brush 16 into the receiving hole 14, completing the adjustment of the brush 16 length. After adjustment, the threaded cap 11 can be rotated in the opposite direction to make the slider 9 move the limiting tooth 10 into the limiting groove 15, thereby fixing the position. Through rapid length adjustment, it can be adapted to different collection scenarios, improving collection efficiency.
[0040] When brush 16 needs to be replaced, by pulling slider 9, the outer part of connecting post 8 slides to the intersection of sliding groove 12 and rotating groove 13. At this time, by pulling slider 9, rotating block 3 rotates. The outer part of rotating tooth 5 of rotating block 3 is squeezed, so that tooth 5 slides out from inside fixed block 4. At this time, brush 16 can be completely disassembled. When replacing other brushes 16, fixed block 4 is slid back into sliding block 2 and rotating block 3. Then, rotating block 3 is rotated in the opposite direction, so that tooth 5 slides back into fixed block 4. This completes the overall fixation of brush 16. Through quick installation and disassembly, work efficiency is improved.
[0041] Finally, it should be noted that the above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A mouse skin cell collection brush, comprising a housing (1), characterized in that: The housing (1) is slidably connected to a sliding block (2), the rear end of the sliding block (2) is rotatably connected to a rotating block (3), the top end of the rotating block (3) is fixedly connected to a connecting post (8), the sliding block (2) is slidably connected to a fixing block (4), the connecting post (8) is slidably connected to the outside of the housing (1), the front end of the fixing block (4) is fixedly connected to a brush (16), the connecting post (8) is provided with a limiting component for limiting position, and the rotating block (3) is provided with a disassembly and assembly component for disassembly and assembly.
2. The mouse skin cell collection brush according to claim 1, characterized in that: The limiting component includes a slider (9), the inside of which is slidably connected to the outside of the connecting post (8), the outside of which is threadedly connected to a threaded cap (11), the bottom end of which is fixedly connected to a limiting tooth (10), and the outside of the housing (1) is provided with a limiting groove (15), the outside of which is slidably connected to the inside of the limiting groove (15).
3. The mouse skin cell collection brush according to claim 1, characterized in that: The outer side of the housing (1) is provided with a sliding groove (12) and a rotating groove (13).
4. The mouse skin cell collection brush according to claim 1, characterized in that: The housing (1) has a storage hole (14) inside, and a handle (17) is fixedly connected to the rear end of the housing (1).
5. The mouse skin cell collection brush according to claim 1, characterized in that: The assembly and disassembly assembly includes a sliding tooth (5), the top of which is fixedly connected to a telescopic column (7), and a telescopic spring (6) is sleeved on the outside of the telescopic column (7). The outside of the sliding tooth (5) is slidably connected to the inside of the fixed block (4).
6. The mouse skin cell collection brush according to claim 5, characterized in that: The bottom end of the telescopic spring (6) is fixedly connected to the top end of the sliding tooth (5), and the other end of the telescopic spring (6) is fixedly connected to the inside of the rotating block (3).
7. The mouse skin cell collection brush according to claim 5, characterized in that: The top end of the telescopic column (7) is fixedly connected to the inside of the rotating block (3), and the outside of the fixed block (4) is rotatably connected to the inside of the rotating block (3).
8. The mouse skin cell collection brush according to claim 3, characterized in that: The brush (16) is externally slidably connected to the inside of the housing (1), and the connecting post (8) is externally slidably connected to the inside of the rotating groove (13).