Frozen cell transfer box

By designing a cryocell transfer box, which uses a metal storage rack and liquid nitrogen adsorption block structure, combined with composite polystyrene foam material, the problems of insufficient temperature and safety hazards during cell transfer are solved, and safe and convenient ultra-low temperature preservation is achieved.

CN223844787UActive Publication Date: 2026-01-30上海翊尘生物技术有限公司
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Patent Information

Application Number
CN202520450162.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-14
Publication Date
2026-01-30
Estimated Expiration
2035-03-14

AI Technical Summary

Technical Problem

In existing technologies, dry ice is not hot enough during cell transfer, liquid nitrogen is inconvenient to use and poses safety hazards, the operation is complicated, and it is difficult and costly to prepare it in the laboratory.

Method used

A cryogenic cell transfer box was designed, which uses a metal plate-shaped storage rack and a liquid nitrogen adsorption block, combined with composite polystyrene foam insulation material. It utilizes the ultra-low temperature of liquid nitrogen to preserve cells, avoiding direct contact between liquid nitrogen and cryopreservation tubes. The stability and sealing are improved by snap-fit ​​components.

Benefits of technology

It enables the maintenance of ultra-low temperature conditions for extended periods in small devices, preventing liquid nitrogen leakage, improving operational safety, reducing costs, and facilitating portability and use.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a frozen cell transfer box which comprises a heat preservation box body, a storage part which is detachably arranged in the heat preservation box body and is used for storing cryopreservation tubes, and a heat preservation box cover which is detachably arranged at the upper end of the heat preservation box body, so that the heat preservation box body is sealed and covered by the heat preservation box cover. According to the invention, a material with super-strong adsorption capacity to liquid nitrogen is adopted, and the adsorbed liquid nitrogen is retained in the transfer box in a gas phase form, so that the liquid nitrogen is prevented from entering the cryopreservation tube, and the liquid nitrogen is safer to both samples and people; the low temperature of the liquid nitrogen at the bottom is transferred to all samples through the metal storage rack with good heat conduction, and even if the amount of the liquid nitrogen is very small, the cells can be always kept in an ultralow temperature condition (-100 DEG C); and the composite polystyrene foam with excellent thermal insulation performance is selected as the thermal insulation box, so that the thermal insulation box is safer and more durable, and the thermal insulation effect is more durable.
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Description

TECHNICAL FIELD

[0001] The utility model relates to transfer box technical field, concretely is a kind of frozen cell transfer box. BACKGROUND

[0002] Cell culture is one of the most important experimental techniques in the field of life sciences, and the quality of cell seeds is a key factor affecting cell culture results. Cell seeds are usually stored in liquid nitrogen at -196℃. Frozen cell transfer also requires ultra-low temperature.

[0003] Currently, many cell transfers are carried out using dry ice. The temperature of dry ice can only reach -78.5℃, and it is still necessary to use liquid nitrogen to maintain a temperature below -100℃. Moreover, laboratories cannot produce dry ice themselves, and each use requires advance ordering, resulting in high purchase costs and inconvenience. If cells are directly placed in liquid nitrogen, the temperature can also be lowered to below -100℃, but placing threaded cryopreservation tubes directly into liquid nitrogen can easily contaminate the samples and is very inconvenient to operate. Liquid nitrogen entering the cryopreservation tube can also cause the tube to burst when removed, posing a significant threat to the safety of the operator. Therefore, a frozen cell transfer box is needed. SUMMARY

[0004] The technical problem solved by the utility model lies in providing a frozen cell transfer box to solve the problems raised in the background.

[0005] The technical problem solved by the utility model is solved by the following technical solution: a frozen cell transfer box, comprising a heat preservation box body, a storage part detachably arranged in the heat preservation box body for storing cryopreservation tubes, and a heat preservation box cover detachably arranged at the upper end of the heat preservation box body to cover the heat preservation box body.

[0006] The storage part comprises a storage rack and a liquid nitrogen suction accessory clamped on the storage rack. The storage rack comprises a fixed plate for placing cryopreservation tubes, a support plate arranged at the lower end of the fixed plate for supporting the cryopreservation tubes, and a heat conducting plate mounted at the lower end of the support plate. The fixed plate has a plurality of storage holes for placing cryopreservation tubes. The liquid nitrogen suction accessory has a slot hole for placing cryopreservation tubes corresponding to the storage hole. Specifically, the cryopreservation tubes are placed in the storage holes, and the cryopreservation tubes can be wrapped in liquid nitrogen to store the cryopreservation tubes using the ultra-low temperature of the liquid nitrogen.

[0007] As a further scheme of the utility model:

[0008] The fixed plate, support plate and heat conducting plate are in the form of metal plates to facilitate low-temperature conduction and improve the heat preservation effect on the cryopreservation tubes. The fixed plate, support plate and heat conducting plate are arranged in sequence with a spacing and are fixedly connected by metal rods distributed around them, and low-temperature conduction can be carried out through the metal rods.

[0009] As a further scheme of the utility model,

[0010] The liquid nitrogen adsorption member includes a first liquid nitrogen adsorption block and a second liquid nitrogen adsorption block, the first liquid nitrogen adsorption block is clamped between the fixed plate and the supporting plate, and a slot hole is arranged on the first liquid nitrogen adsorption block, and the second liquid nitrogen adsorption block is clamped between the supporting plate and the heat conduction plate.

[0011] As a further scheme of the utility model,

[0012] The adsorption material in the first liquid nitrogen adsorption block and the second liquid nitrogen adsorption block is one or several of nano sponge, molecular sieve or urea-formaldehyde foam.

[0013] As a further scheme of the utility model,

[0014] A groove is arranged on the inner side of the upper end of the heat preservation box body, the lower end of the heat preservation box cover is provided with a sealing block inserted into the groove, so that the heat preservation box cover is embedded and installed on the heat preservation box body, the sealing effect is improved, and handle grooves for facilitating personnel operation are arranged on the two sides of the heat preservation box cover.

[0015] As a further scheme of the utility model,

[0016] The fixed plate is arranged around the groove bottom wall and is clamped between the heat preservation box body and the sealing block, so that the stability of the storage part is improved.

[0017] As a further scheme of the utility model,

[0018] The heat preservation box body and the heat preservation box cover are made of composite polystyrene foam material.

[0019] As a further scheme of the utility model,

[0020] A clamping assembly is further arranged between the heat preservation box cover and the heat preservation box body, so that the heat preservation box cover is clamped and installed on the upper end of the heat preservation box body.

[0021] As a further scheme of the utility model,

[0022] The clamping assembly includes a first clamping hook installed on the upper end of the heat preservation box body and a second clamping hook arranged at a corresponding position of the heat preservation box cover, the first clamping hook is symmetrically installed on the two sides of the heat preservation box body, the heat preservation box cover is provided with a clamping groove corresponding to the first clamping hook, and the second clamping hook is elastically installed in the clamping groove through a spring, and the upper end of the first clamping hook and the lower end of the second clamping hook are provided with inclined surfaces that slide with each other, so that the first clamping hook can be buckled with the second clamping hook in the lifting process.

[0023] As a further scheme of the utility model,

[0024] The heat preservation box cover is further provided with a pull rod for pulling the first clamping hook to move, one end of the pull rod is connected with the second clamping hook, the other end is connected with a push handle, and a sliding groove is arranged at the middle part of the heat preservation box cover and corresponds to the push handle, so as to facilitate a person to push the push handle, and the second clamping hook is pulled away from the first clamping hook through the pull rod, so as to facilitate opening of the heat preservation box cover.

[0025] Compared with the prior art, the heat preservation box has the advantages that:

[0026] The liquid nitrogen adsorption material has super strong adsorption capacity for liquid nitrogen, the adsorbed liquid nitrogen is retained in the transfer box in the form of gas phase, liquid nitrogen cannot enter the cryopreservation tube, and the sample and the person are safer; the low temperature of the bottom liquid nitrogen is transmitted to all samples through the metal storage rack with good heat conduction, even a small amount of liquid nitrogen can keep the cells in the super low temperature condition (-100 DEG C) all the time; the composite polystyrene foam with excellent heat preservation performance is selected as the heat preservation box, which is safer, more durable and has more durable heat preservation effect.

[0027] The first liquid nitrogen adsorption block and the second liquid nitrogen adsorption block are high-efficiency liquid nitrogen adsorption materials, liquid nitrogen can be well retained in the "micropore" of the material after entering the material, and exists in the form of gas phase for a longer time; the freezing cell transfer process does not involve liquid phase, the sample is safer, and the threat of low-temperature frostbite to the operator is avoided; the external heat preservation box adopts dense, environmentally friendly and light composite polystyrene foam heat preservation material, does not generate debris or foam particles, and avoids the possibility of pollution to the environment or cell room, isolator and the like; the heat preservation effect is much better than that of an ordinary foam box, and a small volume can keep for several hours; the device is small in size and can be conveniently placed in a safety cabinet, and is more convenient to operate.

[0028] The heat preservation box cover and the heat preservation box body are further provided with a clamping assembly, the heat preservation box cover is clamped and installed on the upper end of the heat preservation box body, the stability of connection with the heat preservation box body can be improved, and personnel carrying is facilitated. BRIEF DESCRIPTION OF DRAWINGS

[0029] Figure 1 It is a structural schematic view of the utility model;

[0030] Figure 2 It is an exploded structural schematic view of the utility model Figure 1 ;

[0031] Figure 3 It is an exploded structural schematic view of the utility model Figure 2 ;

[0032] Figure 4 It is a clamping assembly structural schematic view of the utility model;

[0033] Figure 5 It is Figure 4 an enlarged structural schematic view of the middle A.

[0034] Identified in the figure: 1, the incubator box; 2, the cryopreservation tube; 3, the storage part; 4, the incubator cover; 5, the clamping assembly; 31, the fixed plate; 32, the support plate; 33, the heat conduction plate; 34, the metal rod; 35, the first liquid nitrogen adsorption block; 36, the second liquid nitrogen adsorption block; 41, the sealing block; 42, the handle groove; 51, the first clamping hook; 52, the second clamping hook; 53, the clamping groove; 54, the spring; 55, the pull rod; 56, the push handle. DETAILED DESCRIPTION

[0035] In order to make the technical means, the creation features, the purposes and the effects of the utility model easy to understand, the utility model is further described below in combination with specific drawings.

[0036] As shown in the drawings, Figures 1-5

[0037] The utility model provides a frozen cell transfer box, including incubator box 1, the storage part 3 that can be detachable in incubator box 1 is used to store the cryopreservation tube 2, the incubator cover 4 that can be detachable in the upper end of incubator box 1, to through the incubator cover 4 seal cover incubator box 1;

[0038] The storage part 3 includes storage rack and liquid nitrogen adsorption subassembly clamped on the storage rack, the storage rack includes the fixed plate 31 for placing the cryopreservation tube 2 and the support plate 32 for supporting the cryopreservation tube 2 and is set in the lower end of fixed plate 31, the heat conduction plate 33 installed in the lower end of support plate 32, a plurality of groups of storage holes for placing the cryopreservation tube 2 are set up on the fixed plate 31, and the slot hole for placing the cryopreservation tube 2 is set up in the liquid nitrogen adsorption subassembly corresponding storage hole. Specifically, the cryopreservation tube 2 is placed in the storage hole, the cryopreservation tube 2 can be wrapped in liquid nitrogen, and the cryopreservation tube 2 is preserved by using the ultralow temperature of liquid nitrogen.

[0039] In the embodiment, the fixed plate 31, the support plate 32 and the heat conduction plate 33 are metal plate structures, so as to facilitate low-temperature conduction and improve the incubation effect on the cryopreservation tube 2, the fixed plate 31, the support plate 32 and the heat conduction plate 33 are sequentially and spacedly arranged and fixedly connected through the metal rods 34 distributed around, and low-temperature conduction can be realized through the metal rods 34.

[0040] The liquid nitrogen adsorption subassembly includes the first liquid nitrogen adsorption block 35 and the second liquid nitrogen adsorption block 36, the first liquid nitrogen adsorption block 35 is clamped between the fixed plate 31 and the support plate 32, and the slot hole is set up on the first liquid nitrogen adsorption block 35, and the second liquid nitrogen adsorption block 36 is clamped between the support plate 32 and the heat conduction plate 33.

[0041] The adsorption material in the first liquid nitrogen adsorption block 35 and the second liquid nitrogen adsorption block 36 is one or several of nanometer sponge, molecular sieve or urea-formaldehyde foam.

[0042] ​In the embodiment, a recess is formed in the inner side of the upper end of the heat preservation box body 1, and the lower end of the heat preservation box cover 4 is provided with a sealing block 41 inserted into the recess, so that the heat preservation box cover 4 is embeddedly installed on the heat preservation box body 1, the sealing effect is improved, and handle grooves 42 are formed in the two sides of the heat preservation box cover 4 for facilitating personnel operation.

[0043] The fixing plate 31 is arranged around the recess bottom wall and clamped between the heat preservation box body 1 and the sealing block 41, so that the stability of the storage part 3 is improved.

[0044] The heat preservation box body 1 and the heat preservation box cover 4 are made of composite polystyrene foam material.

[0045] In the embodiment, the heat preservation box cover 4 and the heat preservation box body 1 are further provided with a clamping assembly 5 to clamp the heat preservation box cover 4 on the upper end of the heat preservation box body 1, so as to avoid the heat preservation box cover 4 from being separated from the heat preservation box body 1, improve the stability of the connection between the heat preservation box cover 4 and the heat preservation box body 1, and facilitate personnel carrying.

[0046] The clamping assembly 5 comprises first clamping hooks 51 installed on the upper end of the heat preservation box body 1 and second clamping hooks 52 arranged at corresponding positions of the heat preservation box cover 4, the first clamping hooks 51 are symmetrically installed on the two sides of the heat preservation box body 1, the heat preservation box cover 4 is provided with clamping grooves 53 corresponding to the first clamping hooks 51, the second clamping hooks 52 are elastically installed in the clamping grooves 53 through springs 54, and the upper end of the first clamping hook 51 and the lower end of the second clamping hook 52 are provided with inclined surfaces that slide with each other, so that the first clamping hook 51 can be buckled with the second clamping hook 52 during the lifting process.

[0047] The heat preservation box cover 4 is further provided with a pull rod 55 for pulling the first clamping hook 51 to move, one end of the pull rod 55 is connected with the second clamping hook 52, the other end is connected with a push handle 56, a sliding groove is formed in the middle of the heat preservation box cover 4 corresponding to the push handle 56, so as to facilitate personnel to push the push handle 56, and the second clamping hook 52 is pulled away from the first clamping hook 51 through the pull rod 55, so as to facilitate opening of the heat preservation box cover 4.

[0048] The basic principle and main features of the present application and the advantages of the present application are shown and described above. It should be understood by those skilled in the art that the present application is not limited by the above examples, and the above examples and descriptions in the specification are only to illustrate the principles of the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the claimed present application. The scope of protection of the present application is defined by the appended claims and their equivalents. It should be noted that in this document, if there are relationship terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between the entities or operations. Moreover, the terms "include", "contain" or any other variants thereof are intended to cover non-exclusive inclusion, so that the process, method, article or device including a series of elements not only includes those elements, but also includes other elements not explicitly listed or inherent to such process, method, article or device. Without further limitation, the element defined by the statement "including a" does not exclude the presence of additional identical elements in the process, method, article or device including the element.

Claims

1. A cryogenic cell transfer case characterized by: The application relates to a cryopreservation box, which comprises a cryopreservation box body (1), a storage part (3) which can be disassembled in the cryopreservation box body (1) and is used for storing cryopreservation tubes (2), and a cryopreservation box cover (4) which can be disassembled at the upper end of the cryopreservation box body (1) and is used for covering the cryopreservation box body (1) through the cryopreservation box cover (4). The storage part (3) comprises a storage rack and a liquid nitrogen adsorption accessory which is clamped on the storage rack; the storage rack comprises a fixing plate (31) which is used for placing the cryopreservation tubes (2), a supporting plate (32) which is arranged at the lower end of the fixing plate (31) and is used for supporting the cryopreservation tubes (2), and a heat conduction plate (33) which is arranged at the lower end of the supporting plate (32); a plurality of groups of storage holes which are used for placing the cryopreservation tubes (2) are formed in the fixing plate (31); and the liquid nitrogen adsorption accessory is provided with groove holes which are used for placing the cryopreservation tubes (2) and correspond to the storage holes.

2. The cryogenic cell transfer box of claim 1, wherein: The fixing plate (31), the supporting plate (32) and the heat conduction plate (33) are in the form of metal plates, so that low-temperature conduction is facilitated, the heat preservation effect on the cryopreservation tubes (2) is improved, the fixing plate (31), the supporting plate (32) and the heat conduction plate (33) are arranged in sequence and are spaced apart, are fixedly connected through metal rods (34) which are distributed around, and can conduct low temperature through the metal rods (34).

3. The cryogenic cell transfer box of claim 2, wherein: The liquid nitrogen adsorption accessory comprises first liquid nitrogen adsorption blocks (35) and second liquid nitrogen adsorption blocks (36); the first liquid nitrogen adsorption blocks (35) are clamped between the fixing plate (31) and the supporting plate (32), and the groove holes are formed in the first liquid nitrogen adsorption blocks (35); and the second liquid nitrogen adsorption blocks (36) are clamped between the supporting plate (32) and the heat conduction plate (33).

4. The cryogenic cell transfer box of claim 3, wherein: The adsorption materials in the first liquid nitrogen adsorption blocks (35) and the second liquid nitrogen adsorption blocks (36) are urea-formaldehyde foams.

5. The cryogenic cell transfer box of claim 2, wherein: A recess is formed in the inner side of the upper end of the cryopreservation box body (1); the lower end of the cryopreservation box cover (4) is provided with a sealing block (41) which is inserted into the recess, so that the cryopreservation box cover (4) is embeddedly installed on the cryopreservation box body (1); and handle grooves (42) which are convenient for personnel to operate are arranged on the two sides of the cryopreservation box cover (4).

6. The cryogenic cell transfer box of claim 5, wherein: The fixing plate (31) is arranged around the bottom wall of the recess and is clamped between the cryopreservation box body (1) and the sealing block (41), so that the stability of the storage part (3) is improved.

7. The cryogenic cell transfer box of claim 1, wherein: The cryopreservation box body (1) and the cryopreservation box cover (4) are made of composite polystyrene foam material.

8. The cryogenic cell transfer box of claim 1, wherein: A clamping assembly (5) is further arranged between the cryopreservation box cover (4) and the cryopreservation box body (1), so that the cryopreservation box cover (4) is clamped and installed on the upper end of the cryopreservation box body (1).

9. The cryogenic cell transfer box of claim 8, wherein: The clamping assembly (5) comprises first clamping hooks (51) which are arranged on the upper end of the cryopreservation box body (1) and second clamping hooks (52) which are arranged at corresponding positions of the cryopreservation box cover (4); the first clamping hooks (51) are symmetrically arranged on the two sides of the cryopreservation box body (1); the cryopreservation box cover (4) is provided with clamping grooves (53) which correspond to the first clamping hooks (51); the second clamping hooks (52) are elastically arranged in the clamping grooves (53) through springs (54); and the upper end of the first clamping hook (51) and the lower end of the second clamping hook (52) are provided with inclined surfaces which slide with each other, so that the first clamping hook (51) can be buckled with the second clamping hook (52) during the lifting process of the first clamping hook (51).

10. The cryogenic cell transfer box of claim 9, wherein: The heat preservation box cover (4) is further provided with a pull rod (55) for pulling the first clamping hook (51) to move, one end of the pull rod (55) is connected with the second clamping hook (52), the other end is connected with a push handle (56), and a sliding groove is formed in the middle part of the heat preservation box cover (4) corresponding to the push handle (56).