Chromatographic separation and purification equipment

Abstract

The chromatographic separation and purification equipment comprises a purification box body, a top plate, a bottom plate and a scraping plate, a first opening and a second opening are formed in the upper end and the lower end of the purification box body respectively, and the top plate and the bottom plate which are used for sealing the first opening and the second opening are hinged to the first opening and the second opening through hinges respectively. The top plate and the bottom plate are connected with the purification box body through connecting assemblies, the scraping plate is attached to the inner wall of the purification box body in a sliding mode, the purification box body is provided with a driving assembly used for driving the scraping plate to rotate, and the driving assembly is detachably connected with the scraping plate. After purification operation, workers do not need to manually clean the inner wall of the purification box body, so that the working intensity of the workers when the workers clean the inner wall of the purification box is effectively reduced, and the scraping plate can be detached and cleaned after the device is cleaned, so that the cleaning efficiency is improved. Therefore, the inner wall cleaning stability of the device after purification is effectively improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of purification technology, especially to a chromatographic separation and purification equipment. BACKGROUND

[0002] In the chemical production synthesis process, the synthesized or extracted compounds often need to be separated and purified, and chromatography is a common separation and purification method in the field of pharmaceutical or chemical synthesis. A purification tank is needed when chromatographic purification is performed.

[0003] The existing purification tank is often cylindrical, and the inner wall often sticks to the previous raw materials after use. Therefore, the inner wall of the existing purification tank needs to be cleaned after use. However, due to the length of the purification tank, the inner wall is difficult to clean, which affects the subsequent purification operation. UTILITY MODEL CONTENT

[0004] (I) Utility model purpose

[0005] To solve the technical problems in the background art, the utility model provides a chromatographic separation and purification equipment. After purification operation, the staff does not need to manually clean the inner wall of the purification tank body, thereby effectively reducing the work intensity of the staff when cleaning the inner wall of the purification tank, and the device can also be disassembled and cleaned after cleaning, thereby effectively improving the stability of the device when cleaning the inner wall after purification.

[0006] (II) Technical scheme

[0007] The utility model provides a chromatographic separation and purification equipment, including purification tank body, top plate, bottom plate and scraper, the first opening and the second opening are equipped with top plate and bottom plate respectively for sealing in the upper and lower ends of the purification tank body, the top plate and the bottom plate are connected with the purification tank body through the connecting assembly, the scraper is in close sliding contact with the inner wall of the purification tank body, the purification tank body is equipped with a driving assembly for driving the scraper to rotate, and the driving assembly is detachably connected with the scraper.

[0008] Preferably, the driving assembly includes a transmission ring, the transmission ring is rotatably arranged in the purification tank body, a first notch is provided on the transmission ring, an installation unit is detachably arranged at the first notch, the installation unit is connected with the scraper, and a rotating unit is provided on the purification tank body for driving the transmission ring to rotate.

[0009] Preferably, the installation unit includes a transmission block and a limiting block. A first groove is provided inside the first notch. The transmission block is slidably disposed in the first notch. The bottom end of the transmission block is connected to the scraper. The two ends of the transmission block are respectively connected to the limiting block. The limiting block is slidably disposed in the first groove and fits against the inner wall of the first groove.

[0010] Preferably, the rotating unit includes a threaded head and a mounting plate. The top plate is provided with a second groove, and the mounting plate is rotatably disposed in the second groove. The mounting plate is provided with a first threaded through hole, and the top plate is provided with a first through hole communicating with the first threaded through hole. The threaded head is threaded into the first threaded through hole, and the transmission ring is provided with a second through hole. The mounting plate can rotate with the top plate until the first threaded through hole and the second through hole communicate with each other, and the threaded head can move into the second through hole and slide against its inner wall. The mounting plate can also rotate to be in contact with the upper end of the transmission ring.

[0011] Preferably, it also includes a motor and a rotating shaft. The top plate is provided with a third through hole coaxially arranged with the mounting plate. The rotating shaft is rotatably disposed in the third through hole and coaxially connected with the mounting plate. The motor is connected to the end of the top plate away from the mounting plate through a mounting bracket. The output shaft of the motor is coaxially connected with the rotating shaft.

[0012] Preferably, the connecting assembly includes a first mounting plate, a second mounting plate, and a bolt. The first mounting plate is connected to the top plate, and the second mounting plate is located below the first mounting plate and connected to the outer end of the purification chamber body. The first mounting plate is provided with a second threaded through hole, and the second mounting plate is provided with a corresponding third threaded through hole. One end of the bolt passes through the second threaded through hole and the third threaded through hole in sequence, and the bolt is threadedly connected to the first mounting plate and the second mounting plate respectively.

[0013] Compared with the prior art, the above-mentioned technical solution of this utility model has the following beneficial technical effects:

[0014] In this invention, after purification, the device eliminates the need for manual cleaning of the inner wall of the purification chamber, effectively reducing the workload of cleaning the inner wall. Furthermore, the scraper can be disassembled and cleaned after cleaning, thus improving the stability of cleaning the inner wall after purification. Attached Figure Description

[0015] Fig. 1 This is a schematic diagram of the structure of a chromatography separation and purification device proposed in this utility model.

[0016] Fig. 2This is a schematic diagram of the internal structure of a chromatography separation and purification device proposed in this utility model.

[0017] Fig. 3 This is a partially enlarged structural diagram of point A in a chromatography separation and purification device proposed in this utility model.

[0018] Reference numerals in the attached drawings: 1. Purification chamber body; 2. Top plate; 3. Bottom plate; 5. Hinge; 6. Transmission ring; 7. Transmission block; 8. Scraper; 9. Limiting block; 10. Threaded cylinder; 11. Mounting plate; 12. Mounting bracket; 13. Motor; 14. Rotating shaft; 15. First mounting plate; 16. Second mounting plate; 17. Bolt. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings. It should be understood that these descriptions are merely exemplary and not intended to limit the scope of this utility model. Furthermore, descriptions of well-known structures and technologies are omitted in the following description to avoid unnecessarily obscuring the concept of this utility model.

[0020] In the description of this utility model, it should be noted that the terms "upper," "lower," "inner," "outer," "front end," "rear end," "both ends," "one end," and "the other end," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used solely for the convenience of describing this utility model and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0021] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installed," "equipped with," and "connected," etc., should be interpreted broadly. For example, "connected" can be a fixed connection, such as welding, riveting, or bonding; it can also be a detachable connection, such as threaded connection, keyed connection, or pin connection; or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; or it can be a connection within two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0022] like Figs. 1-3As shown, the present invention proposes a chromatography separation and purification device, including a purification chamber body 1, a top plate 2, a bottom plate 3, and a scraper 8. The purification chamber body 1 has a first opening and a second opening at its upper and lower ends, respectively. The first opening and the second opening are respectively hinged to the top plate 2 and the bottom plate 3 for sealing. The top plate 2 and the bottom plate 3 are connected to the purification chamber body 1 through connecting components. The scraper 8 slides against the inner wall of the purification chamber body 1. The purification chamber body 1 is provided with a driving component for driving the scraper 8 to rotate. The driving component is detachably connected to the scraper 8.

[0023] In this invention, the device can perform purification operations through the purification chamber body 1. After purification and material discharge, the second opening can be opened, and the scraper 8 can be moved by the drive component to clean the inner wall of the purification chamber body 1. The material is then discharged through the second opening. After cleaning, the first opening can be opened. Since the drive component and the scraper 8 are detachably connected, the scraper 8 can be directly disassembled and cleaned. After purification, the device eliminates the need for manual cleaning of the inner wall of the purification chamber body 1, effectively reducing the workload of cleaning the inner wall of the purification chamber body 1. Furthermore, the scraper 8 can be disassembled and cleaned after cleaning, effectively improving the stability of the device in cleaning the inner wall after purification.

[0024] In an optional embodiment, the driving assembly includes a transmission ring 6 rotatably disposed within the purification chamber body 1. The transmission ring 6 has a first notch, and an installation unit is detachably disposed at the first notch. The installation unit is connected to the scraper 8. The purification chamber body 1 is provided with a rotating unit for driving the transmission ring 6 to rotate. The rotating unit drives the transmission ring 6 to rotate, and the rotation of the transmission ring 6 drives the installation unit to rotate, thereby driving the scraper 8 to rotate to clean the inner wall of the purification chamber body 1. The scraper 8 is connected to the installation unit, and the installation unit is detachably connected to the transmission ring 6. Thus, after cleaning the purification chamber body 1, the scraper 8 can be disassembled by removing the installation unit, which facilitates cleaning of the scraper 8 and reduces the workload of the staff when cleaning the scraper 8.

[0025] In an optional embodiment, the installation unit includes a transmission block 7 and a limiting block 9. A first groove is provided inside the first notch. The transmission block 7 is slidably disposed in the first notch. The bottom end of the transmission block 7 is connected to the scraper 8. The two ends of the transmission block 7 are respectively connected to the limiting block 9. The limiting block 9 is slidably disposed in the first groove and fits against the inner wall of the first groove. When the transmission block 7 is inserted into the first notch, it drives the limiting block 9 into the first groove. The first groove can limit the limiting block 9, thereby limiting the transmission block 7. The transmission ring 6 drives the transmission block 7 to rotate, thereby driving the scraper 8 to rotate. After opening the first opening, the transmission block 7 can be directly removed, thereby removing the scraper 8. Disassembly is convenient, thus effectively reducing the workload of workers when cleaning the scraper 8.

[0026] In an optional embodiment, the rotating unit includes a threaded head 10 and a mounting plate 11. The top plate 2 has a second groove, and the mounting plate 11 is rotatably disposed within the second groove. The mounting plate 11 has a first threaded through hole, and the top plate 2 has a first through hole communicating with the first threaded through hole. The threaded head 10 is threaded into the first threaded through hole, and the transmission ring 6 has a second through hole. The mounting plate 11 can rotate with the top plate 2 until the first threaded through hole and the second through hole communicate with each other. The threaded head 10 can move into the second through hole and slide against its inner wall. The mounting plate 11 can also rotate to be in contact with the upper end of the transmission ring 6. When it is necessary to drive the transmission ring 6 to rotate, the top plate 2 is rotated. When the top plate 2 rotates, it drives the mounting plate 11 to rotate until it is in contact with the transmission ring 6, and the second through hole corresponds to the first threaded through hole. Thus, by rotating the threaded head 10, the threaded head 10 moves as it rotates, enters the second through hole, and is no longer located in the first through hole. Then, the mounting plate 11 rotates, which drives the threaded head 10 in the first threaded through hole to rotate. Since one end of the threaded head 10 is located in the second through hole, the threaded head 10 will drive the transmission ring 6 to rotate as it follows the mounting plate 11. After the threaded head 10 enters the second through hole, it is in contact with its inner wall. Under the action of the inner wall of the second through hole, the threaded head 10 can also be limited, thus initially limiting the mounting plate 11 and the top plate 2, thereby improving the stability of the device.

[0027] In an optional embodiment, the system further includes a motor 13 and a rotating shaft 14. The top plate 2 has a third through hole coaxially arranged with the mounting plate 11. The rotating shaft 14 is rotatably disposed in the third through hole and coaxially connected to the mounting plate 11. The motor 13 is connected to the end of the top plate 2 away from the mounting plate 11 via a mounting bracket 12. The output shaft of the motor 13 is coaxially connected to the rotating shaft 14. The mounting bracket 12 is connected to the end of the top plate 2 away from the mounting plate 11. The motor 13 is connected to the mounting bracket 12. The motor 13 drives the rotating shaft 14 to rotate, and the rotation of the rotating shaft 14 sequentially drives the mounting plate 11, which is coaxially connected to it, to rotate.

[0028] In an optional embodiment, the connecting assembly includes a first mounting plate 15, a second mounting plate 16, and a bolt 17. The first mounting plate 15 is connected to the top plate 2, and the second mounting plate 16 is located below the first mounting plate 15 and connected to the outer end of the purification chamber body 1. The first mounting plate 15 has a second threaded through hole, and the second mounting plate 16 has a corresponding third threaded through hole. One end of the bolt 17 passes through the second threaded through hole and the third threaded through hole in sequence. The bolt 17 is threadedly connected to the first mounting plate 15 and the second mounting plate 16, respectively. When it is necessary to connect the top plate 2 and the bottom plate 3 to the purification chamber body 1, the top plate 2 or the bottom plate 3 is rotated to make the first mounting plate 15 and the second mounting plate 16 parallel, and to make the second threaded through hole and the third threaded through hole communicate with each other. Rotating the bolt 17 through the third threaded through hole can limit the position between the first mounting plate 15 and the second mounting plate 16, thereby completing the connection and fixation between the top plate 2 or the bottom plate 3 and the purification chamber body 1.

[0029] It should be understood that the specific embodiments described above are merely illustrative or explanatory of the principles of this utility model and do not constitute a limitation thereof. Therefore, any modifications, equivalent substitutions, improvements, etc., made without departing from the spirit and scope of this utility model should be included within its protection scope. Furthermore, the appended claims are intended to cover all variations and modifications falling within the scope and boundaries of the appended claims, or equivalent forms of such scope and boundaries.

Claims

1. A chromatographic separation and purification device, characterized in that, The purification chamber includes a purification chamber body (1), a top plate (2), a bottom plate (3), and a scraper (8). The purification chamber body (1) has a first opening and a second opening at its upper and lower ends, respectively. The first opening and the second opening are respectively hinged to the top plate (2) and the bottom plate (3) for sealing by hinges (5). The top plate (2) and the bottom plate (3) are connected to the purification chamber body (1) by connecting components. The scraper (8) slides against the inner wall of the purification chamber body (1). The purification chamber body (1) is provided with a driving component for driving the scraper (8) to rotate. The driving component is detachably connected to the scraper (8).

2. The chromatographic separation and purification apparatus according to claim 1, characterized in that, The driving component includes a transmission ring (6), which is rotatably disposed inside the purification chamber body (1). The transmission ring (6) has a first notch, and an installation unit is detachably provided at the first notch. The installation unit is connected to the scraper (8). The purification chamber body (1) is provided with a rotating unit for driving the transmission ring (6) to rotate.

3. The chromatographic separation and purification apparatus according to claim 2, characterized in that, The installation unit includes a transmission block (7) and a limiting block (9). A first groove is provided inside the first notch. The transmission block (7) is slidably disposed in the first notch. The bottom end of the transmission block (7) is connected to the scraper (8). The two ends of the transmission block (7) are respectively connected to the limiting block (9). The limiting block (9) is slidably disposed in the first groove and fits against the inner wall of the first groove.

4. The chromatographic separation and purification apparatus according to claim 3, characterized in that, The rotating unit includes a threaded head (10) and a mounting plate (11). The top plate (2) is provided with a second groove. The mounting plate (11) is rotatably disposed in the second groove. The mounting plate (11) is provided with a first threaded through hole. The top plate (2) is provided with a first through hole that communicates with the first threaded through hole. The threaded head (10) is threaded into the first threaded through hole. The transmission ring (6) is provided with a second through hole. The mounting plate (11) can rotate with the top plate (2) until the first threaded through hole and the second through hole communicate with each other. The threaded head (10) can move into the second through hole and slide against its inner wall. The mounting plate (11) can rotate to be in contact with the upper end of the transmission ring (6).

5. The chromatographic separation and purification apparatus according to claim 4, characterized in that, It also includes a motor (13) and a rotating shaft (14). The top plate (2) is provided with a third through hole coaxially arranged with the mounting plate (11). The rotating shaft (14) is rotatably arranged in the third through hole and coaxially connected with the mounting plate (11). The motor (13) is connected to the end of the top plate (2) away from the mounting plate (11) through the mounting bracket (12). The output shaft of the motor (13) is coaxially connected with the rotating shaft (14).

6. The chromatographic separation and purification apparatus according to claim 1, characterized in that, The connecting assembly includes a first mounting plate (15), a second mounting plate (16), and a bolt (17). The first mounting plate (15) is connected to the top plate (2). The second mounting plate (16) is located below the first mounting plate (15) and connected to the outer end of the purification chamber body (1). The first mounting plate (15) has a second threaded through hole, and the second mounting plate (16) has a corresponding third threaded through hole. One end of the bolt (17) passes through the second threaded through hole and the third threaded through hole in sequence. The bolt (17) is threadedly connected to the first mounting plate (15) and the second mounting plate (16) respectively.

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