Improved L-p-hydroxyphenylglycine central control sampler

By designing an improved L-hydroxyphenylglycine central control sampler, the problem of uneven sampling in large packages was solved, enabling multi-layer and multi-point sampling, ensuring the accuracy and safety of test results, and reducing costs.

CN223870365UActive Publication Date: 2026-02-03HENAN NEWLAND PHARMACEUTICAL CO LTD
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Patent Information

Application Number
CN202520141741.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-21
Publication Date
2026-02-03
Estimated Expiration
2035-01-21

AI Technical Summary

Technical Problem

Existing sampling tools cannot achieve multi-layer, multi-point, and fixed-point sampling when sampling intermediate or finished products in large packages, resulting in uneven sampling results that cannot truly reflect the quality status of materials and affect the accuracy of test results.

Method used

An improved L-hydroxyphenylglycine central control sampler was designed, including an outer tube and a sampling core. The outer tube surface is provided with sampling holes at different heights, and the core is provided with multiple sampling slots that can rotate freely to ensure sampling at different heights and points. The material is rigid PP or stainless steel to avoid sample spillage.

Benefits of technology

It enables multi-layer, multi-point, and fixed-point sampling, ensuring the representativeness and reliability of test results, reducing safety risks, and is convenient and inexpensive to operate.

✦ Generated by Eureka AI based on patent content.

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Abstract

The technical scheme of the utility model relates to an improved L-p-hydroxyphenylglycine central control sampler, and belongs to the technical field of product test sampling tools and quality control. The device consists of an outer tube, a sampling inner core, different point position sampling grooves, a sample injection hole and the like, and is mainly characterized in that the sampling inner core can freely rotate in the outer tube and is provided with the sampling grooves with different heights; therefore, during sampling operation, the sampler can extend into each layer and corner of a target object, the representativeness of samples at different point positions and the credibility of test results are ensured, and the quality of the target object can be accurately researched and judged objectively and fairly. The improved L-p-hydroxyphenylglycine central control sampler disclosed by the technical scheme of the utility model also has the advantages of simple structure, low cost, easiness in manufacturing, convenience in operation, safety and reliability.
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Description

Technical Field

[0001] This utility model belongs to the field of product testing and sampling tools and quality control technology, and specifically relates to an improved L-hydroxyphenylglycine central control sampler. Background Technology

[0002] L-hydroxyphenylglycine is a white crystalline solid with a molecular weight of 167.16 and is an important pharmaceutical intermediate. It is not only an important fine chemical product, but also an indispensable side-chain acid in the synthesis of broad-spectrum antibiotics such as amoxicillin, cefadroxil, cefoperazone, cefuroxime, and cefhydroxylamine.

[0003] In the production process of L-p-hydroxyphenylglycine, the quality control of intermediate products is an important part of quality assurance. The uniformity of the obtained samples directly determines the accuracy of the test results, which in turn directly affects the accurate assessment of the quality of intermediate products.

[0004] When the production process of L-p-hydroxyphenylglycine is changed to use large-package "ton bags" to hold intermediate or finished products, the requirements for central control samplers become increasingly stringent. To prevent significant quality differences among materials or intermediate products labeled as being from the same batch, or to prevent the mixing and circulation of low-content materials, it is necessary to uniformly sample and test different layers and corners of a batch or package of material to ensure that the test data is accurate, valid, and reliable, thereby providing positive guidance for production operations. Current sampling tools have problems such as not being able to perform targeted sampling at a specific point or having uneven sampling results. When sampling large packages, only the material on the upper surface can be obtained, and the sampling results cannot truly reflect the quality status of the middle and lower parts of the sampled material, resulting in weak sample representativeness. Summary of the Invention

[0005] To address the above problems and the shortcomings of existing technologies, this utility model provides an improved L-hydroxyphenylglycine central control sampler. It can accurately sample large-package intermediate products or multiple layers, multiple points, and fixed points of products in one go. It has a simple structure, saves time and effort, is safe and reliable, and has high work efficiency. At the same time, it avoids the phenomenon of sample spillage when moving the previous sampler, and has a better application effect.

[0006] This utility model discloses an improved L-hydroxyphenylglycine central control sampler, comprising: an outer tube, an outer tube handle, a sampling port, a cone, a sampling inner core, sampling slots A, B, and C, and an inner core handle. The improved L-hydroxyphenylglycine central control sampler consists of an outer tube and a sampling inner core. The outer tube surface has sampling ports of different heights, a cone at the bottom, and a handle at the top. The sampling inner core is located inside the outer tube, with a handle at its top. The lower part of the sampling inner core contains sampling slots A, B, and C of different heights. This design allows the outer tube and sampling inner core to be separated and combined, making it convenient to carry and clean, and easy to operate. The sampling slots of different heights can accurately obtain material from different or disputed locations.

[0007] Preferably, the improved L-hydroxyphenylglycine central control sampler described in this utility model is characterized in that both the outer tube and the sampling inner core are made of rigid PP or stainless steel. The outer tube has a diameter of 15-40 mm and a length of 200-1000 mm. The sampling inner core has a diameter of 14-39 mm and a length of 200-1000 mm, and the sampling inner core can rotate freely inside the outer tube. This design aims to ensure that the rigid PP tube is resistant to corrosion from acidic or alkaline materials, and that the freely rotating sampling inner core ensures accurate acquisition of materials at different heights and locations.

[0008] Preferably, the improved L-hydroxyphenylglycine central control sampler described in this utility model is characterized in that the inlet holes on the surface of the outer tube are vertically arranged, with 3 to 6 inlet holes arranged from top to bottom. This design aims to select a sampler with the appropriate number of inlet holes based on the size of the material packaging.

[0009] Preferably, the improved L-hydroxyphenylglycine central control sampler described in this utility model is characterized in that sampling slot A, sampling slot B, and sampling slot C are sequentially arranged from top to bottom in the lower middle part of the sampling core, and its shape is a hollow semi-cylinder with a sealed bottom. This design aims to enable sampling slots of different heights to sample points at different heights.

[0010] Preferably, the improved L-hydroxyphenylglycine central control sampler described in this utility model is characterized in that the sampling slots A, B, and C are spaced 100-200 mm apart. This design aims to maintain a certain distance between the sampling slots to prevent cross-contamination of materials at different heights and locations, which could lead to inaccurate sampling at specific points.

[0011] The improved L-hydroxyphenylglycine central control sampler described in this utility model has the following significant advantages: 1. It allows for free rotation of the sampling core and the setting of sampling holes at different heights, ensuring the representativeness of the sample and the reliability of the test results; 2. The sampling process is relatively closed, avoiding sample spillage and direct contact with sampling personnel, thus reducing safety risks; 3. The sampling slots A, B, and C, spaced a certain distance apart, can accurately obtain materials at different points, ensuring the authenticity of fixed-point sampling; 4. It also has the advantages of simple structure, low cost, easy manufacturing, and convenient operation. Attached Figure Description

[0012] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.

[0013] Figure 1 This is a schematic diagram of the outer tube and sampling core of an improved L-hydroxyphenylglycine central control sampler as described in the embodiment of the present invention.

[0014] Figure 1 In the middle: outer tube 01, outer tube handle 02, sample inlet 03, cone 04, sampling core 05, core handle 06, sampling groove A07, sampling groove B08, sampling groove C09.

[0015] Figure 2 This is a schematic diagram illustrating the operation steps of an improved L-hydroxyphenylglycine central control sampler as described in an embodiment of the present invention.

[0016] Figure 2 In the middle: the sampler is inserted into the material 01, the sampling core is rotated in the reverse direction to start sampling, the sampling core is rotated in the forward direction to close the sampling groove 03, the sampler is pulled out 04, and the sampled sample is poured out 05. Detailed Implementation

[0017] To make the objectives, technical solutions, and advantages of this utility model clearer, the following description is provided in conjunction with the appendix. Figure 1 and attached Figure 2 The embodiments of this utility model will be further described below.

[0018] The improved L-hydroxyphenylglycine central control sampler described in this specific embodiment includes: an outer tube 01, an outer tube handle 02, a sample inlet 03, a cone 04, a sampling inner core 05, an inner core handle 06, a sampling groove A07, a sampling groove B08, and a sampling groove C09.

[0019] This embodiment describes an improved L-hydroxyphenylglycine central control sampler, characterized in that it comprises an outer tube 01 and a sampling inner core 05. The outer tube 01 has inlet holes 03 of varying heights on its surface, a conical head 04 at its bottom, and an outer tube handle 02 at its top. The sampling inner core 05 is located inside the outer tube 01, with an inner core handle 06 at its top. The lower part of the sampling inner core 05 contains sampling slots A07, B08, and C09. This design allows the outer tube and sampling inner core to be separated and combined, making it convenient to carry and clean. Operation is easy and flexible, and the sampling slots of different heights can accurately obtain material from different or disputed locations.

[0020] Furthermore, the improved L-hydroxyphenylglycine central control sampler described in this specific embodiment is characterized in that both the outer tube and the sampling inner core are made of rigid PP or stainless steel. The outer tube has a diameter of 15–40 mm and a length of 200–1000 mm. The sampling inner core has a diameter of 14–39 mm and a length of 200–1000 mm, and the sampling inner core can rotate freely inside the outer tube. This design aims to ensure that the rigid PP tube is resistant to corrosion from acidic or alkaline materials, and that the freely rotating sampling inner core ensures accurate acquisition of materials at different heights and locations.

[0021] Furthermore, the improved L-hydroxyphenylglycine central control sampler described in this specific embodiment is characterized in that the inlet holes on the surface of the outer tube are vertically arranged, with 3 to 6 inlet holes arranged from top to bottom. The purpose of this design is to select a sampler with the appropriate number of inlet holes based on the size of the material packaging.

[0022] Furthermore, the improved L-hydroxyphenylglycine central control sampler described in this specific embodiment is characterized in that sampling slot A, sampling slot B, and sampling slot C are sequentially arranged from top to bottom in the lower middle part of the sampling core, and its shape is a hollow semi-cylinder with a sealed bottom. The purpose of this design is to enable sampling slots of different heights to sample points at different heights.

[0023] Furthermore, in this specific embodiment, the improved L-hydroxyphenylglycine central control sampler is characterized in that the sampling slots A, B, and C are spaced 100-200 mm apart. This design aims to maintain a certain distance between the sampling slots to prevent cross-contamination of materials at different heights and locations, which could lead to inaccurate sampling at specific points.

[0024] Furthermore, referring to Figure 2The improved L-hydroxyphenylglycine central control sampler described in this specific embodiment can be simply operated as follows: First, rotate the sampling core so that the sampling slots face away from the inlet hole, and then insert the sampler into the material; Second, rotate the sampling core in the opposite direction so that sampling slots A, B, and C face the inlet hole, and begin sampling; Third, rotate the sampling core in the forward direction to close the sampling slots; Fourth, pull the sampler upward; Fifth, pull out the sampling core, pour the samples taken from different points into the material tray for collection, and sampling is complete; Sixth, clean the outer tube and the sampling core.

[0025] This improved L-hydroxyphenylglycine central control sampler, as described in this utility model, offers several significant advantages: 1) It allows for free rotation of the sampling core and the setting of inlet holes at different heights, ensuring the representativeness of the sample and the reliability of the test results; 2) The sampling process is relatively enclosed, avoiding sample spillage and direct contact with sampling personnel, thus reducing safety risks; 3) The sampling slots A, B, and C, spaced at certain intervals, accurately obtain materials from different locations, ensuring the authenticity of fixed-point sampling; 4) It also boasts advantages such as simple structure, low cost, easy manufacturing, and convenient operation. The general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of this utility model. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of this utility model should be included within the protection scope of this utility model. The protection scope of this utility model is to conform to the widest range consistent with the principles and novel features described herein.

Claims

1. An improved L-hydroxyphenylglycine central control sampler, comprising: The improved L-hydroxyphenylglycine central control sampler comprises an outer tube and a sampling inner core. The outer tube has inlet holes of different heights on its surface, a cone at its bottom, and an outer tube handle at its top. The sampling inner core is located inside the outer tube and has an inner core handle at its top. The lower part of the sampling inner core consists of sampling grooves A, B, and C of different heights.

2. The improved L-hydroxyphenylglycine central control sampler according to claim 1, characterized in that, The outer tube and the sampling inner core are both made of hard PP or stainless steel. The outer tube has a diameter of 15-40 mm and a length of 200-1000 mm. The sampling inner core has a diameter of 14-39 mm and a length of 200-1000 mm. The sampling inner core can rotate freely inside the outer tube.

3. The improved L-hydroxyphenylglycine central control sampler according to claim 1, characterized in that, The sample inlet holes on the surface of the outer tube are arranged vertically, with 3 to 6 sample inlets arranged from top to bottom.

4. The improved L-hydroxyphenylglycine central control sampler according to claim 1, characterized in that, The sampling slots A, B, and C are arranged sequentially from top to bottom in the lower middle part of the sampling core, and their shape is a hollow semi-cylinder with a sealed bottom.

5. The improved L-hydroxyphenylglycine central control sampler according to claim 1, characterized in that, The sampling slots A, B, and C are spaced 100-200 mm apart.