Mesenchymal stem cell exosome storage device convenient to use

Abstract

The utility model discloses a mesenchymal stem cell exosome storage device convenient to use, which comprises an anti-skid leg, a temperature control unit is arranged on the top surface of the anti-skid leg, a material taking unit is arranged in the temperature control unit, an adjusting unit is arranged on the top surface of the temperature control unit, a placing unit is arranged on the bottom side of the adjusting unit, and the placing unit comprises a placing plate. The placing plate is arranged on the bottom side of the adjusting unit, a first rotating wheel is rotationally connected into the placing plate, a clamping block is slidably connected into the placing plate, and a plurality of second rotating wheels are rotationally connected into one side of the clamping block. Through the arrangement of the placing plate, the rotating wheel I, the clamping block, the rotating wheel II and the limiting rod, the effect of conveniently and quickly fixing and limiting a test tube for containing exosomes is achieved, and meanwhile, the friction between the test tube and the clamping block is reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to the storage technical field of mesenchymal stem cell exosome, specifically relates to a kind of storage device of mesenchymal stem cell exosome convenient to use. BACKGROUND

[0002] Mesenchymal stem cells are a kind of multipotent stem cells, it has all the commonness of stem cells, namely self-renewal and multi-directional differentiation ability, in clinical application solves blood system disease, cardiovascular disease, cirrhosis, nervous system disease, knee joint meniscus partial resection damage repair, autoimmune disease etc., is favorable to improve the success rate of transplantation and accelerate hematopoietic reconstruction, can also obviously accelerate patient blood cell recovery time, in addition, mesenchymal stem cells have long-term development prospects in nervous system repair and more aspects.Exosome refers to small membrane vesicles (30-150nm) containing complex RNA and protein, and now refers to disc-shaped vesicles with a diameter of 40-100nm.All cultured cell types can secrete exosomes, and exosomes naturally exist in body fluids, including blood, saliva, urine, cerebrospinal fluid and milk.

[0003] The utility model discloses a kind of stem cell storage devices with the announcement number CN219939494U, including: inner cavity and refrigerator, inner cavity is located in the inside of refrigerator, first cabinet door is equipped on refrigerator, multiple placing plates are equipped in inner cavity, placing plate is slidably connected with the inner side wall of the two sides of inner cavity, first handle is equipped on placing plate, multiple storage dishes are equipped on placing plate, storage dish is used to store stem cell, the two sides of inner cavity are equipped with moving mechanism, moving mechanism includes: fixed plate, electric telescopic rod, mounting plate and universal wheel, fixed plate is fixedly connected on the side wall of inner cavity, the bottom surface of fixed plate is fixedly connected with one end of electric telescopic rod, the other end of electric telescopic rod is fixedly connected with mounting plate, and multiple universal wheels are installed on the bottom of mounting plate.

[0004] In order to solve the problem of inconvenient movement, the prior art, i.e. the aforementioned patent, uses a moving part on both sides of the inner cavity, and the electric telescopic rod of the moving part can be raised and lowered to handle it, but it still cannot limit the placement of test tubes, which may cause the test tubes to fall during movement. UTILITY MODEL CONTENTS

[0005] The utility model aims at providing a kind of storage device of mesenchymal stem cell exosome convenient to use to solve the problems raised in the above background.

[0006] To solve the above technical problems, the technical scheme adopted by the utility model is:

[0007] The utility model provides a storage device of mesenchymal stem cell exosome convenient to use, including antiskid leg, the top surface of antiskid leg is provided with temperature control unit, the inside of temperature control unit is provided with taking unit, the top surface of temperature control unit is provided with adjustment unit, the bottom side of adjustment unit is provided with placement unit, the placement unit includes placement board, is provided with a plurality of test tube clamping structure on the placement board, and the test tube clamping structure includes the C type clamping mouth that opens on the edge of the placement board and is provided with the clamping block at the opening of the C type clamping mouth, the bottom side wall of the C type clamping mouth is provided with a plurality of rotating wheel no.

[0008] The utility model discloses further improve in further improvement of technical scheme of the utility model, the temperature control unit includes temperature control box, temperature control box fixedly connected at the top surface of antiskid leg, one side of temperature control box is provided with temperature controller.

[0009] Adopt above technical scheme, through the setting of temperature control box and temperature controller, the effect that the storage temperature is controlled is convenient.

[0010] The utility model discloses further improve in further improvement of technical scheme of the utility model, one side of temperature control box is provided with visual door, one side of visual door is provided with taking hole, the inside of taking hole is provided with sealing plug.

[0011] Adopt above technical scheme, through the setting of visual door, the effect that the mesenchymal stem cell exosome that the inside storage of temperature control box is observed is convenient, through the setting of taking hole and sealing plug, the effect that test tube is taken individually is convenient.

[0012] The utility model discloses further improve in further improvement of technical scheme of the utility model, the taking unit includes limit block, limit block fixedly connected at the inside bottom surface of temperature control box, the inside of limit block is provided with arc slot.

[0013] Adopt above technical scheme, through the setting of limit block and arc slot, the effect that the test tube bottom that stores exosome is positioned is convenient.

[0014] The further improvement of the utility model technical scheme lies in: the inside of the limiting block is slidably connected with an inclined panel, one side of the inclined panel is fixedly connected with a T-shaped rod one, the inside of the T-shaped rod one is slidably penetrated and arranged in the inside of the temperature control box, the outside of the T-shaped rod one is sleeved with a spring one, one end of the spring one is fixedly connected with one side of the inclined panel, one end of the spring one is fixedly connected with the inside of the temperature control box.

[0015] The above technical scheme has the effect that the inclined panel, the T-shaped rod one and the spring one are arranged to facilitate the separate removal of the test tube containing the exosome, and reduce the temperature loss in the temperature control box.

[0016] The further improvement of the utility model technical scheme lies in: the adjusting unit comprises a rotating rod, the rotating rod is rotationally connected to the top surface of the temperature control box, the inner end of the rotating rod is fixedly connected with the top of the placing plate through a rotating shaft, the surface of the rotating rod is fixedly connected with an adjusting block, and a plurality of adjusting holes are evenly arranged on the circumferential edge of the adjusting block.

[0017] The above technical scheme has the effect that the rotating rod, the adjusting block and the adjusting hole are arranged to facilitate the adjustment of the test tube containing the exosome.

[0018] The further improvement of the utility model technical scheme lies in: a T-shaped rod two is arranged on the temperature control box, the inner end of the T-shaped rod two is slidably connected with the adjusting hole;

[0019] The outside of the T-shaped rod two is sleeved with a spring two, one end of the spring two is fixedly connected with the outside end of the T-shaped rod two, and the other end of the spring two is fixedly connected with the outer wall of the temperature control box.

[0020] The above technical scheme has the effect that the T-shaped rod two and the spring two are arranged to facilitate the limiting of the test tube containing the exosome during storage, and further reduce the displacement and collision problems.

[0021] Due to the adoption of the above technical scheme, the utility model has the following technical progress compared with the prior art:

[0022] 1、The utility model provides a kind of mesenchymal stem cell exosome's storage device convenient to use, and the effect that the test tube containing exosome is fixed and limited quickly is achieved by the setting of placing plate, rotating wheel one, clamping block, rotating wheel two and limiting rod, while reducing the friction between test tube and clamping block, while protecting the exosome in the test tube, the effect that the mesenchymal stem cell exosome stored in the temperature control box is observed is facilitated by the setting of visual door, and the effect that the test tube is individually taken is facilitated by the setting of taking hole and sealing plug.

[0023] 2. This utility model provides a user-friendly storage device for mesenchymal stem cell exosomes. The inclined panel, T-shaped rod 1, and spring 1 facilitate the individual removal of exosome test tubes, reducing temperature loss inside the temperature control chamber. The rotating rod, adjusting block, and adjusting hole facilitate the adjustment of the test tubes for retrieving exosomes. The T-shaped rod 2 and spring 2 facilitate the positioning of the exosome test tubes during storage, further reducing displacement and collision issues. Attached Figure Description

[0024] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0025] Figure 2 This is an exploded structural diagram of the temperature control unit of this utility model;

[0026] Figure 3 This is a schematic diagram of the material handling unit of this utility model;

[0027] Figure 4 This is a schematic diagram of the structure of the adjustment unit of this utility model;

[0028] Figure 5 This is a schematic diagram of the placement unit of this utility model.

[0029] In the diagram: 1. Anti-slip leg; 2. Temperature control unit; 21. Temperature control box; 22. Temperature controller; 23. Viewing door; 24. Material picking hole; 25. Sealing plug; 3. Material picking unit; 31. Limiting block; 32. Arc groove; 33. Slanted panel; 34. T-shaped rod one; 35. Spring one; 4. Adjustment unit; 41. Rotating rod; 42. Adjusting block; 43. Adjusting hole; 44. T-shaped rod two; 45. Spring two; 5. Placement unit; 51. Placement plate; 52. Rotating wheel one; 53. Clamping block; 54. Rotating wheel two; 55. Limiting rod; 56. Spring three. Detailed Implementation

[0030] The present invention will be further described in detail below with reference to embodiments:

[0031] Example 1

[0032] like Figures 1-5 As shown, this utility model provides a user-friendly storage device for mesenchymal stem cell exosomes, including an anti-slip leg 1. A temperature control unit 2 is disposed on the top surface of the anti-slip leg 1. A material dispensing unit 3 is disposed inside the temperature control unit 2. An adjustment unit 4 is disposed on the top surface of the temperature control unit 2. A placement unit 5 is disposed on the bottom side of the adjustment unit 4. The placement unit 5 includes... Figure 3The placement plate 51 is shown, a plurality of test tube clamping structures are arranged on the placement plate 51, the test tube clamping structure includes a C-shaped clamping opening opened on the edge of the placement plate 51 and a clamping block 53 arranged at the opening of the C-shaped clamping opening; a plurality of rotating wheels one 52 are arranged on the bottom side wall of the C-shaped clamping opening; the opposite side walls of the C-shaped clamping opening are each provided with a mounting groove extending from outside to inside, and a limiting rod 55 extending from outside to inside is arranged in the mounting groove; the opposite two ends of the clamping block 53 are arc-shaped ends, and respectively extend to the inner end of the mounting groove on the same side, so that the inner end of the limiting rod 55 on the same side penetrates the arc-shaped end on the same side; the outer end of the limiting rod 55 is sleeved with a spring three 56, and the inner end of the spring three 56 abuts against the arc-shaped end on the same side; the arc-shaped end of the clamping block 53 is provided with a rotating wheel two 54 on the inner side. By opening the visible door 23, the test tube containing exosomes is placed on the inner side of the placement plate 51, that is, the C-shaped clamping opening, then the limiting rod 55 and the spring three 56 are matched, the rotating wheel two 54 and the rotating wheel one 52 are driven to contact the surface of the outer test tube, and the test tube and the clamping block 53 and the placement plate 51 are in elastic contact due to the rolling contact and the compression of the spring three 56, thereby reducing the wear between the test tube and the clamping block 53 and the placement plate 51, and then the test tube is sequentially placed in the C-shaped clamping opening.

[0033] Embodiment 2

[0034] As Figures 1-5 shown, on the basis of embodiment 1, the utility model provides a technical scheme: preferably, the temperature control unit 2 includes temperature control box 21, temperature control box 21 fixed connection is established in the top surface of antiskid leg 1, one side of temperature control box 21 is provided with temperature controller 22, one side of temperature control box 21 is provided with visible door 23, one side of visible door 23 is opened with take out hole 24, the inside of take out hole 24 is provided with sealing plug 25, and take out unit 3 includes limiting block 31, limiting block 31 fixed connection is established in the inside bottom surface of temperature control box 21, the inside of limiting block 31 is provided with arc groove 32, and the inside sliding connection of limiting block 31 has inclined plane plate 33, one side of inclined plane plate 33 is fixedly connected with T-shaped rod one 34, and the inside of T-shaped rod one 34 is slidably penetrated and arranged in the inside of temperature control box 21, and the outside of T-shaped rod one 34 is sleeved with spring one 35, one end of spring one 35 is fixedly connected with one side of inclined plane plate 33, one end of spring one 35 is fixedly connected with the inside one side of temperature control box 21, temperature controller 22 is controlled to adjust the temperature stored, and sealing plug 25 is removed from the inside of take out hole 24 when taking out is needed, then T-shaped rod one 34 is pulled to drive spring one 35 to compress under the limiting of temperature control box 21, at the same time, the bottom side of exosome test tube in the inside of arc groove 32 is contacted by driving inclined plane plate 33, then the test tube is guided to slide out from the inside of take out hole 24 by inclined plane plate 33, and then the test tube containing exosomes can be taken out.

[0035] Embodiment 3

[0036] As Figures 1-5 As shown in Figure 1, on the basis of embodiment 1, the utility model provides a technical scheme: preferably, the adjusting unit 4 includes the rotating rod 41, the rotating rod 41 is rotatably connected to the top surface of the temperature control box 21, the inner end of the rotating rod 41 is fixedly connected with the inside of the placing plate 51 through the rotating shaft, the surface of the rotating rod 41 is fixedly connected with the adjusting block 42, a plurality of adjusting holes 43 are evenly opened along the circumference on the circumferential edge of the adjusting block 42, a T-shaped rod two 44 is arranged on the temperature control box 21, the inner end of the T-shaped rod two 44 that penetrates the temperature control box 21 is in sliding contact with the adjusting hole 43, and the outer side of the T-shaped rod two 44 is provided with a spring two 45, one end of the spring two 45 is fixedly connected to the outer side end of the T-shaped rod two 44, the other end of the spring two 45 is fixedly connected to the outer wall of the temperature control box 21, the T-shaped rod two 44 is pulled to drive the spring two 45 to extend, simultaneously drive the inner end of the T-shaped rod two 44 to slide out from the inside of the adjusting hole 43, then the rotating rod 41 is rotated to drive the placing plate 51 to rotate, the removed test tube is adjusted according to the requirement, simultaneously in the process of rotating, through the connecting relationship between the T-shaped rod two 44 and the adjusting hole 43, the shaking of the internal test tube is further reduced, and the test tube is further protected.

[0037] The working principle of the mesenchymal stem cell exosome storage device will be described below.

[0038] As Figures 1-5 As shown in Figure 1, by opening the visual door 23, the test tube containing the exosome is placed on the inner side of the placing plate 51 by pulling the clamping block 53, then the surface of the test tube is contacted by the rotating wheel two 54 and the rotating wheel one 52 through the cooperation between the limiting rod 55 and the spring three 56, the abrasion between the test tube and the clamping block 53 and the placing plate 51 is reduced, then the test tube is sequentially placed in the inside of the placing plate 51, the temperature of storage is adjusted by controlling the temperature controller 22, simultaneously when the material is taken, the sealing plug 25 is detached from the inside of the material taking hole 24, then the T-shaped rod one 34 is pulled to drive the spring one 35 to compress under the limiting of the temperature control box 21, simultaneously the bottom side of the exosome test tube in the inner side of the arc-shaped groove 32 is contacted by the inclined plane plate 33, then the test tube is guided by the inclined plane plate 33 and slides out from the inside of the material taking hole 24, then the test tube containing the exosome can be taken out, simultaneously the T-shaped rod two 44 is pulled to drive the spring two 45 to extend, simultaneously the T-shaped rod two 44 is pulled out from the inside of the adjusting hole 43, then the rotating rod 41 is rotated to drive the placing plate 51 to rotate, the removed test tube is adjusted according to the requirement, simultaneously in the process of rotating, through the connecting relationship between the T-shaped rod two 44 and the adjusting hole 43, the shaking of the internal test tube is further reduced, and the test tube is further protected.

[0039] The utility model has made the detailed description to the utility model generally above, but can make some modification or improvement to it on the basis of the utility model, this is obvious to the general skilled person in the technical field. Therefore, the modification or improvement without departing from the utility model thought spirit, all are within the protection scope of the utility model.

Claims

1. A user-friendly storage device for mesenchymal stem cell exosomes, comprising anti-slip legs (1), characterized in that: The top surface of the anti-slip leg (1) is provided with a temperature control unit (2), the inside of the temperature control unit (2) is provided with a material handling unit (3), the top surface of the temperature control unit (2) is provided with an adjustment unit (4), and the bottom side of the adjustment unit (4) is provided with a placement unit (5). The placement unit (5) includes a placement plate (51), on which a plurality of test tube clamping structures are provided. The test tube clamping structures include a C-shaped clamping opening on the edge of the placement plate (51) and a clamping block (53) provided at the opening of the C-shaped clamping opening. The bottom sidewall of the C-shaped clamping port is provided with multiple rotating wheels (52); Each of the C-shaped clamping ports has an installation groove extending from the outside to the inside on its opposite sidewalls, and each of the installation grooves has a limiting rod (55) extending from the outside to the inside. The two opposite ends of the clamping block (53) are arc-shaped ends and extend toward the inner end of the mounting groove on the same side, so that the inner end of the limiting rod (55) on that side passes through the arc-shaped end on the same side. A spring three (56) is sleeved on the outer end of the limiting rod (55), and the inner end of the spring three (56) presses against the arc-shaped end on the same side. The inner side of the arc-shaped end of the clamping block (53) is provided with a rotating wheel (54).

2. The storage device according to claim 1, characterized in that: The temperature control unit (2) includes a temperature control box (21), which is fixedly connected to the top surface of the anti-slip leg (1), and a temperature controller (22) is provided on one side of the temperature control box (21).

3. The storage device according to claim 2, characterized in that: The temperature control box (21) is provided with a viewing door (23) on one side, and a material taking hole (24) is provided on one side of the viewing door (23), and a sealing plug (25) is provided inside the material taking hole (24).

4. The storage device according to claim 2, characterized in that: The material handling unit (3) includes a limiting block (31), which is fixedly connected to the inner bottom surface of the temperature control box (21), and an arc groove (32) is provided on the inner side of the limiting block (31).

5. The storage device according to claim 4, characterized in that: The limiting block (31) is internally slidably connected to an inclined plate (33). A T-shaped rod (34) is fixedly connected to one side of the inclined plate (33). The inner side of the T-shaped rod (34) is slidably inserted through the interior of the temperature control box (21). A spring (35) is sleeved on the outer side of the T-shaped rod (34). One end of the spring (35) is fixedly connected to one side of the inclined plate (33), and the other end of the spring (35) is fixedly connected to one side of the interior of the temperature control box (21).

6. The storage device according to claim 2, characterized in that: The adjustment unit (4) includes a rotating rod (41), which is rotatably connected to the top surface of the temperature control box (21). The inner end of the rotating rod (41) is fixedly connected to the top of the placement plate (51) through a rotating shaft. An adjustment block (42) is fixedly connected to the surface of the rotating rod (41). The circumferential edge of the adjustment block (42) is evenly provided with a plurality of circumferentially distributed adjustment holes (43).

7. The storage device according to claim 6, characterized in that: A T-shaped rod (44) is provided on the temperature control box (21), and the inner end of the T-shaped rod (44) that penetrates the temperature control box (21) slides in contact with the adjustment hole (43); A spring (45) is fitted on the outer side of the T-shaped rod (44). One end of the spring (45) is fixedly connected to the outer end of the T-shaped rod (44), and the other end of the spring (45) is fixedly connected to the outer wall of the temperature control box (21).

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