Freezing tube batch cap screwing equipment

The use of a batch capping device for cryopreservation tubes enables rapid batch opening of cryopreservation tubes, solving the problem of caps sticking to the tube body and improving experimental efficiency and result accuracy.

CN223892414UActive Publication Date: 2026-02-10YANTAI HAISHENWEI MEDICAL TECH
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Patent Information

Application Number
CN202520152760.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-22
Publication Date
2026-02-10
Estimated Expiration
2035-01-22

AI Technical Summary

Technical Problem

In existing technologies, the caps and tubes of cryopreservation tubes tend to stick together in low-temperature environments, resulting in low efficiency when opening the cap individually, and opening the cap at long intervals can affect the consistency of the samples.

Method used

Design a batch capping device for cryopreservation tubes, including a cryopreservation tube rack in-and-out drive mechanism, a capping lifting drive mechanism, and a batch capping mechanism for cryopreservation tubes, to achieve simultaneous capping and uncapping of multiple cryopreservation tubes in a mechanized manner.

Benefits of technology

It enables rapid batch opening of cryopreservation tubes, ensuring that all samples are exposed under the same conditions, improving experimental efficiency and the comparability of results, reducing human error, and standardizing and refining the experimental process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses batch cap screwing equipment for cryopreservation tubes. A cryopreservation tube frame carrying cryopreservation tubes to be subjected to cap screwing is transferred to a cap screwing station below a cryopreservation tube batch cap screwing mechanism through a cryopreservation tube frame in-out driving mechanism; a cover screwing lifting driving mechanism is used for controlling a cryopreservation tube batch cover screwing mechanism to move downwards to be in butt joint with the cryopreservation tubes to be subjected to cover screwing in the cryopreservation tube frame located at the cover screwing station; a cap screwing driving motor of the cryopreservation tube batch cap screwing mechanism is controlled to drive a cap screwing assembly of the cryopreservation tube batch cap screwing mechanism to rotate so as to conduct cap screwing on the cryopreservation tubes to be subjected to cap screwing in the cryopreservation tube frame of the cap screwing station at the same time, and cap bodies of the cryopreservation tubes are loosened; and after the cover bodies of the cryopreservation tubes in the cryopreservation tube frame are loosened, a cover withdrawing assembly of the cryopreservation tube batch cover screwing mechanism is controlled to withdraw the cover bodies on the cover screwing heads of the cover screwing assembly. According to the utility model, a plurality of cryopreservation tubes can be uncovered at the same time in a short time, so that the efficiency is improved, and errors caused by manual operation are reduced.
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Description

Technical Field

[0001] This utility model relates to a batch capping device for cryopreservation tubes, belonging to the field of cryopreservation tube processing technology. Background Technology

[0002] Cryopreservation tubes are containers used for cryopreserving biological samples (such as cells, tissues, bacteria, viruses, etc.). They are typically made of cryogenically resistant materials, such as polypropylene. Cryopreservation tubes can preserve samples for extended periods in ultra-low temperature environments such as liquid nitrogen, ensuring the samples' viability and stability. They are available in various sizes and capacities to meet different experimental needs. They are widely used in biomedical research, clinical testing, and other fields.

[0003] Currently, in low-temperature environments, the caps and bodies of cryovials may stick together due to condensation or sample leakage, making them difficult to open. This is especially true when hand strength is limited or unsuitable tools are used. Furthermore, many biological laboratories and biobanks store large quantities of cryovial samples. For example, large-scale cell culture experiments may require the simultaneous thawing of dozens or even hundreds of cryovials. Opening them one by one would be extremely time-consuming. For samples sensitive to time and environmental changes, failing to open them in batches could lead to inconsistencies due to excessively long opening intervals. Utility Model Content

[0004] Therefore, this utility model provides a batch capping device for cryopreservation tubes to achieve batch capping of cryopreservation tubes, thereby solving the problems of low efficiency and sample inconsistency caused by excessively long time intervals between capping.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a batch capping device for cryopreservation tubes, including an outer shell, with a cryopreservation tube rack inlet and outlet formed on the side of the outer shell, a central plate provided inside the outer shell, and a cryopreservation tube rack drive clearance opening formed at the bottom of the central plate; it also includes a cryopreservation tube rack inlet / outlet drive mechanism, a capping lifting drive mechanism, and a batch capping mechanism for cryopreservation tubes.

[0006] The cryopreservation tube rack in / out drive mechanism is located at the bottom inner side of the outer shell. The cryopreservation tube rack in / out drive mechanism includes a cryopreservation tube rack tray, which passes through the cryopreservation tube rack drive clearance opening. A cryopreservation tube rack placement groove is formed at the end of the cryopreservation tube rack tray.

[0007] The cap lifting drive mechanism includes a lifting drive motor and a lifting slide rail. The lifting drive motor is fixed to one side of the central plate, and the lifting slide rail is fixed to the other side of the central plate.

[0008] The cryopreservation tube batch capping mechanism is connected to the lifting slide rail via a lifting slider, and the cryopreservation tube rack entry and exit drive mechanism moves the cryopreservation tube rack in the cryopreservation tube rack placement slot to the bottom of the cryopreservation tube batch capping mechanism.

[0009] The lifting drive motor is also connected to the cryopreservation tube batch capping mechanism via a lifting transmission belt, and the lifting drive motor drives the cryopreservation tube batch capping mechanism to move up and down along the lifting slide rail via the lifting transmission belt;

[0010] The batch capping mechanism for cryopreservation tubes moves downward to align with and unscrew the caps of the cryopreservation tubes placed in the cryopreservation tube rack on the cryopreservation tube rack placement slot.

[0011] As a preferred embodiment of the batch capping equipment for cryopreservation tubes, the cryopreservation tube rack entry and exit drive mechanism further includes a cryopreservation tube rack entry and exit drive motor, a cryopreservation tube rack entry and exit drive rack, a cryopreservation tube rack entry and exit transmission slide rail, and a cryopreservation tube rack entry and exit transmission slider.

[0012] The cryopreservation tube rack in / out drive motor is fixed to the side of the central plate, the cryopreservation tube rack in / out drive rack is fixed to the bottom of the cryopreservation tube rack tray, and the drive end of the cryopreservation tube rack in / out drive motor meshes with the cryopreservation tube rack in / out drive rack through gears.

[0013] The cryopreservation tube rack in / out transmission slide rail is fixed to the bottom of the outer shell, and the cryopreservation tube rack in / out transmission slide rail is connected to the cryopreservation tube rack tray through the cryopreservation tube rack in / out transmission slider.

[0014] As a preferred embodiment of the batch capping equipment for cryopreservation tubes, the cryopreservation tube rack tray is formed with a transmission clearance strip hole. The drive end of the cryopreservation tube rack entry and exit drive motor passes through the transmission clearance strip hole and then meshes with the cryopreservation tube rack entry and exit drive rack through a gear.

[0015] A clearance is formed between the drive motor for the cryopreservation tube rack and the upper surface of the cryopreservation tube rack tray.

[0016] As a preferred embodiment of the batch capping equipment for cryopreservation tubes, the lifting drive motor of the capping lifting drive mechanism is a dual-shaft electric motor; the capping lifting drive mechanism also includes a first transmission idler wheel, a first tensioning wheel, a second tensioning wheel, a second transmission idler wheel, and a transmission belt fixing seat;

[0017] The first drive idler wheel, the first tension wheel, and the second tension wheel are all connected to the side of the neutral plate, and the second drive idler wheel is located at the bottom of the outer casing.

[0018] One end of the lifting transmission belt is connected to the upper part of the transmission belt fixing seat, and the other end of the lifting transmission belt passes over the first transmission idler wheel, the first tensioning wheel, the drive wheel of the lifting drive motor, the second tensioning wheel, and the second transmission idler wheel before connecting to the lower part of the transmission belt fixing seat.

[0019] As a preferred embodiment of the batch capping equipment for cryopreservation tubes, the batch capping mechanism for cryopreservation tubes includes a batch capping mounting stand, a batch capping mounting top plate, a batch capping transmission support plate, a capping drive motor, and a capping assembly.

[0020] The upper part of the batch capping mounting stand is connected to the batch capping mounting top plate. The transmission belt fixing seat is connected to the outer side of the top of the batch capping mounting stand. The batch capping transmission support plate is connected to the inner side of the middle part of the batch capping mounting stand and is located below the batch capping mounting stand. The capping drive motor is located at the upper end of the batch capping mounting top plate. The capping drive motor is connected to the capping assembly, and the capping assembly passes through the batch capping mounting top plate and the batch capping transmission support plate.

[0021] As a preferred embodiment of the batch capping equipment for cryopreservation tubes, the capping assembly includes a capping end gear, a gear transmission shaft, a gear body, a clutch shaft, and a capping head;

[0022] The capping end gear meshes with the drive end gear of the capping drive motor. The upper end of the gear transmission shaft is connected to the capping end gear. The lower part of the gear transmission shaft passes through the batch capping mounting top plate and connects to the top of the gear body. The gear body engages with the top clutch groove of the clutch shaft. The clutch shaft passes through the batch capping transmission support plate, and the capping head is connected to the lower end of the clutch shaft.

[0023] The number of the capping assemblies is M×N, where M is the number of columns and N is the number of rows;

[0024] One capping drive motor is configured for every four capping assemblies, and the drive end gear of one capping drive motor simultaneously meshes with the capping end gears of four adjacent capping assemblies.

[0025] As a preferred embodiment of the batch capping equipment for cryopreservation tubes, the batch capping mechanism for cryopreservation tubes further includes a cap removal assembly; the cap removal assembly includes a cap removal motor mounting plate, a cap removal drive motor, a first cap removal adapter plate, a second cap removal adapter plate, a cap removal plate body, and upper and lower cap removal guide rails;

[0026] The cap removal motor mounting plate is connected to the front of the batch cap-screwing mounting stand, and the cap removal drive motor is connected to the cap removal motor mounting plate; the first cap removal adapter plate is connected to the drive end of the cap removal drive motor, and the second cap removal adapter plate is connected to the first cap removal adapter plate.

[0027] The lower end of the cover-removing plate body is connected to the lower end of the second cover-removing adapter plate, the capping head is located below the cover-removing plate body, and the clutch shaft passes through the cover-removing plate body and is inserted into the capping head;

[0028] The upper and lower guide rails for cap removal are connected to the side of the batch cap mounting stand, and the second cap removal adapter plate is connected to the upper and lower guide rails for cap removal via upper and lower sliders.

[0029] This utility model has the following advantages: The cryopreservation tube rack carrying the cryopreservation tubes to be capped is transferred to the capping station below the batch capping mechanism of the cryopreservation tube rack via the cryopreservation tube rack in-and-out drive mechanism; the batch capping mechanism of the cryopreservation tube rack is controlled to move downwards to align with the cryopreservation tubes to be capped in the cryopreservation tube rack at the capping station; the capping drive motor of the batch capping mechanism of the cryopreservation tube rack is controlled to rotate the capping assembly of the batch capping mechanism of the cryopreservation tube rack, so as to simultaneously cap the cryopreservation tubes to be capped in the cryopreservation tube rack at the capping station, thus loosening the caps of the cryopreservation tubes; after the caps of the cryopreservation tubes in the cryopreservation tube rack are loosened, the cap removal assembly of the batch capping mechanism of the cryopreservation tube rack is controlled to remove the caps from the capping head of the capping assembly. This invention allows for the simultaneous opening of multiple cryovials in a short period of time, enabling rapid acquisition of the required samples and thus accelerating the experimental or testing process. Furthermore, it allows for the batch opening of a group of tissue sample cryovials, ensuring that all samples are exposed to the same environmental conditions at the same time, thereby better controlling experimental variables and making experimental results more comparable and accurate. This not only improves efficiency but also reduces errors caused by manual operation, making the entire experimental process more standardized and precise. Attached Figure Description

[0030] To more clearly illustrate the embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are merely exemplary, and those skilled in the art can derive other embodiments based on the provided drawings without creative effort.

[0031] Figure 1 This is a first-view three-dimensional structural diagram of the internal structure of the batch capping device for cryopreservation tubes provided in this embodiment of the utility model.

[0032] Figure 2This is a second-view three-dimensional structural diagram of the internal structure of the batch capping device for cryopreservation tubes provided in this embodiment of the utility model.

[0033] Figure 3 This is a third-view perspective three-dimensional structural diagram of the internal structure of the batch capping device for cryopreservation tubes provided in this embodiment of the utility model;

[0034] Figure 4 This is a four-dimensional structural diagram of the internal fourth-view structure of the batch capping device for cryopreservation tubes provided in this embodiment of the present invention.

[0035] Figure 5 This is a five-dimensional perspective view of the internal structure of the batch capping device for cryopreservation tubes provided in this embodiment of the present invention.

[0036] Figure 6 This is a first-view perspective three-dimensional structural diagram of the batch capping mechanism for cryopreservation tubes provided in this embodiment of the utility model.

[0037] Figure 7 This is a second-view three-dimensional structural diagram of the batch capping mechanism for cryopreservation tubes provided in the embodiments of this utility model;

[0038] Figure 8 This is a third-view perspective three-dimensional structural diagram of the batch capping mechanism for cryopreservation tubes provided in the embodiments of this utility model;

[0039] Figure 9 This is a schematic diagram of the internal structure of the batch capping mechanism for cryopreservation tubes provided in this embodiment of the utility model.

[0040] Figure 10 This is a schematic diagram of the capping assembly structure of the batch capping mechanism for cryopreservation tubes provided in this embodiment of the present invention.

[0041] In the diagram, 1. Outer shell; 2. Cryopreservation tube rack inlet / outlet; 3. Central plate; 4. Cryopreservation tube rack drive clearance opening; 5. Cryopreservation tube rack tray; 6. Cryopreservation tube rack placement slot; 7. Lifting drive motor; 8. Lifting slider; 9. Lifting slide rail; 10. Cryopreservation tube rack in / out drive motor; 11. Cryopreservation tube rack in / out drive rack; 12. Cryopreservation tube rack in / out transmission slide rail; 13. Cryopreservation tube rack in / out transmission slider; 14. Transmission clearance bar hole; 15. Clearance clearance; 16. First transmission idler wheel; 17. First tension wheel; 18. Second tension wheel; 19. Second transmission idler wheel; 20. Transmission belt fixing seat; 21. Batch capping mounting stand; 22. Batch capping mounting top plate; 23. Batch capping transmission support plate; 24. Capping drive motor; 25. Capping assembly; 26. Capping end gear; 27. Gear drive shaft; 28. Gear body; 29. ​​Clutch shaft; 30. Capping head; 31. Clutch groove; 32. Cap removal assembly; 33. Cap removal motor mounting plate; 34. Cap removal drive motor; 35. First cap removal adapter plate; 36. Second cap removal adapter plate; 37. Cap removal plate body; 38. Upper and lower cap removal guide rails; 39. Upper and lower cap removal sliders;

[0042] I. Cryopreservation tube rack entry and exit drive mechanism; II. Capping and lifting drive mechanism; III. Cryopreservation tube batch capping mechanism. Detailed Implementation

[0043] The following specific embodiments illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0044] See Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 This utility model provides a batch capping device for cryopreservation tubes, including an outer shell 1, a cryopreservation tube rack inlet and outlet 2 formed on the side of the outer shell 1, a central plate 3 provided inside the outer shell 1, and a cryopreservation tube rack drive clearance opening 4 formed at the bottom of the central plate 3; it also includes a cryopreservation tube rack inlet and outlet drive mechanism I, a capping lifting drive mechanism II, and a batch capping mechanism III for cryopreservation tubes.

[0045] The cryopreservation tube rack in / out drive mechanism I is located at the bottom inner side of the outer shell 1. The cryopreservation tube rack in / out drive mechanism I includes a cryopreservation tube rack tray 5, which passes through the cryopreservation tube rack drive clearance opening 4. A cryopreservation tube rack placement groove 6 is formed at the end of the cryopreservation tube rack tray 5. The cap lifting drive mechanism II includes a lifting drive motor 7 and a lifting slide rail 9. The lifting drive motor 7 is fixed on one side of the central plate 3, and the lifting slide rail 9 is fixed on the other side of the central plate 3.

[0046] The cryopreservation tube batch capping mechanism III is connected to the lifting slide rail 9 via the lifting slider 8. The cryopreservation tube rack entry and exit drive mechanism I transfers the cryopreservation tube rack in the cryopreservation tube rack placement slot 6 to the bottom of the cryopreservation tube batch capping mechanism III. The lifting drive motor 7 is also connected to the cryopreservation tube batch capping mechanism III via the lifting transmission belt (not shown). The lifting drive motor 7 drives the cryopreservation tube batch capping mechanism III to move up and down along the lifting slide rail 9 via the lifting transmission belt. The cryopreservation tube batch capping mechanism III moves downward to align with and unscrew the cryopreservation tube caps placed in the cryopreservation tube rack on the cryopreservation tube rack placement slot 6.

[0047] See Figure 3 , Figure 4 and Figure 5 In this embodiment, the cryopreservation tube rack entry and exit drive mechanism I further includes a cryopreservation tube rack entry and exit drive motor 10, a cryopreservation tube rack entry and exit drive rack 11, a cryopreservation tube rack entry and exit transmission slide rail 12, and a cryopreservation tube rack entry and exit transmission slider 13.

[0048] The cryopreservation tube rack in / out drive motor 10 is fixed to the side of the central plate 3, the cryopreservation tube rack in / out drive rack 11 is fixed to the bottom of the cryopreservation tube rack tray 5, and the drive end of the cryopreservation tube rack in / out drive motor 10 meshes with the cryopreservation tube rack in / out drive rack 11 through gears; the cryopreservation tube rack in / out transmission slide rail 12 is fixed to the bottom of the outer shell 1, and the cryopreservation tube rack in / out transmission slide rail 12 is connected to the cryopreservation tube rack tray 5 through the cryopreservation tube rack in / out transmission slider 13.

[0049] Specifically, the cryopreservation tube rack in / out drive motor 10 is fixed to the side of the central plate 3. The function of the cryopreservation tube rack in / out drive motor 10 is to provide power for the in / out movement of the cryopreservation tube rack by meshing the gear at the drive end with the cryopreservation tube rack in / out drive rack 11. The cryopreservation tube rack in / out drive rack 11 is fixed to the bottom of the cryopreservation tube rack tray 5, and the cryopreservation tube rack in / out transmission slide rail 12 is fixed to the bottom of the outer shell 1. It is connected to the cryopreservation tube rack tray 5 through the cryopreservation tube rack in / out transmission slider 13, which guides the in / out movement of the cryopreservation tube rack tray 5.

[0050] The cryopreservation tube rack tray 5 has a transmission clearance strip hole 14. The drive end of the cryopreservation tube rack entry and exit drive motor 10 passes through the transmission clearance strip hole 14 and then meshes with the cryopreservation tube rack entry and exit drive rack 11 through a gear. A clearance gap 15 is formed between the cryopreservation tube rack entry and exit drive motor 10 and the upper end face of the cryopreservation tube rack tray 5.

[0051] Specifically, the cryopreservation tube rack tray 5 has a transmission clearance slot 14. This design provides a channel for the drive end of the cryopreservation tube rack in / out drive motor 10 to mesh with the cryopreservation tube rack in / out drive rack 11. After the drive end of the cryopreservation tube rack in / out drive motor 10 passes through the transmission clearance slot 14, it meshes with the cryopreservation tube rack in / out drive rack 11 through gears, thereby driving the cryopreservation tube rack tray 5. The clearance gap 15 formed between the upper end face of the cryopreservation tube rack in / out drive motor 10 and the cryopreservation tube rack tray 5 prevents interference between the two cryopreservation tube rack trays during operation, ensuring the normal operation of the equipment.

[0052] See Figure 3 , Figure 4 and Figure 5 In this embodiment, the lifting drive motor 7 of the cap lifting drive mechanism II is a dual-shaft electric motor; the cap lifting drive mechanism II also includes a first transmission idler wheel 16, a first tension wheel 17, a second tension wheel 18, a second transmission idler wheel 19, and a transmission belt fixing seat 20; the first transmission idler wheel 16, the first tension wheel 17, and the second tension wheel 18 are all connected to the side of the central plate 3, and the second transmission idler wheel 19 is located at the bottom of the outer shell 1; one end of the lifting transmission belt is connected to the upper part of the transmission belt fixing seat 20, and the other end of the lifting transmission belt passes around the first transmission idler wheel 16, the first tension wheel 17, the drive wheel of the lifting drive motor 7, the second tension wheel 18, and the second transmission idler wheel 19 and then connects to the lower part of the transmission belt fixing seat 20.

[0053] Specifically, the lifting drive motor 7 of the capping and lifting drive mechanism II is a dual-shaft electric motor, providing power for the lifting and lowering of the cryopreservation tube batch capping mechanism III. The first transmission idler wheel 16, the first tensioning wheel 17, and the second tensioning wheel 18 are connected to the side of the central plate 3, and the second transmission idler wheel 19 is located at the bottom of the outer shell 1. The reasonable positional distribution ensures the normal operation of the capping and lifting drive mechanism II. Among them, one end of the lifting transmission belt is connected to the upper part of the transmission belt fixing seat 20, and the other end passes around the first transmission idler wheel 16, the first tensioning wheel 17, the drive wheel of the lifting drive motor 7, the second tensioning wheel 18, and the second transmission idler wheel 19 before connecting to the lower part of the transmission belt fixing seat 20, forming a complete lifting transmission system.

[0054] See Figure 6 , Figure 7 , Figure 8 and Figure 9In this embodiment, the batch capping mechanism III for cryopreservation tubes includes a batch capping mounting stand 21, a batch capping mounting top plate 22, a batch capping transmission support plate 23, a capping drive motor 24, and a capping assembly 25. The upper part of the batch capping mounting stand 21 is connected to the batch capping mounting top plate 22, the transmission belt fixing seat 20 is connected to the outer side of the top of the batch capping mounting stand 21, and the batch capping transmission support plate 23 is connected to the inner side of the middle part of the batch capping mounting stand 21, with the batch capping transmission support plate 23 located below the batch capping mounting stand 21. The capping drive motor 24 is located at the upper end of the batch capping mounting top plate 22. The capping drive motor 24 is connected to the capping assembly 25, which passes through the batch capping mounting top plate 22 and the batch capping transmission support plate 23.

[0055] Specifically, the capping drive motor 24 serves as the power source, generating rotational power when it starts. This power is transmitted to the capping assembly 25 via the motor shaft. Since the capping assembly 25 passes through the batch capping mounting top plate 22 and the batch capping transmission support plate 23, the rotational motion of the capping drive motor 24 can be effectively transmitted to all parts of the capping assembly 25, providing power for the capping operation. Specifically, the capping assembly 25 begins to rotate under the drive of the capping drive motor 24, and the batch capping mounting stand 21 provides a supporting structure for the entire capping process. The batch capping mounting top plate 22 connected to the upper part of the batch capping mounting stand 21 and the batch capping transmission support plate 23 connected to the inner side of the middle part together ensure that the capping assembly 25 rotates in a stable position.

[0056] See Figure 9 and Figure 10 In this embodiment, the capping assembly 25 includes a capping end gear 26, a gear drive shaft 27, a gear body 28, a clutch shaft 29, and a capping head 30. The capping end gear 26 meshes with the drive end gear of the capping drive motor 24. The upper end of the gear drive shaft 27 is connected to the capping end gear 26, and the lower part of the gear drive shaft 27 passes through the batch capping mounting top plate 22 and connects to the top of the gear body 28. The gear body 28 and the top clutch groove 31 of the clutch shaft 29 cooperate. The clutch shaft 29 passes through the batch capping transmission support plate 23, and the capping head 30 is connected to the lower end of the clutch shaft 29.

[0057] Specifically, the power of the cap-driving motor 24 is transmitted to the cap-end gear 26 in the cap-driving assembly 25 via the drive-end gear. This gear meshing method ensures efficient power transmission and allows for appropriate conversion of speed and torque. The cap-end gear 26 is connected to the upper end of the gear drive shaft 27, and the gear drive shaft 27 rotates when the cap-end gear 26 rotates. The lower part of the gear drive shaft 27 passes through the batch cap mounting top plate 22 and connects to the top of the gear body 28, thus transmitting power from the cap-end gear 26 above the top plate to the gear body 28.

[0058] The top clutch groove 31 of the gear body 28 and the clutch shaft 29 engages, enabling clutch control of the capping assembly 25 during operation. For example, when the capping head 30 needs to be replaced or the equipment needs to be debugged, the clutch structure can be controlled to disengage the capping head 30 from the power unit. The clutch shaft 29 passes through the batch capping transmission support plate 23, ensuring the stability of the clutch shaft 29 during rotation. The position of the clutch shaft 29 is accurately fixed in the support structure of the device.

[0059] Since the capping head 30 is connected to the lower end of the clutch shaft 29, when power is transmitted to the capping head 30, the capping head 30 can perform the capping operation on the cryovial cap. The specific structure of the capping head 30 can vary depending on the type and size of the cryovial cap. For example, for round cryovial caps, the capping head 30 has a groove that matches the edge of the cryovial cap or a rubber ring with high friction to ensure that it can effectively grip the cryovial cap.

[0060] In this embodiment, the number of capping assemblies 25 is M×N, where M is the number of columns and N is the number of rows; every four capping assemblies 25 are equipped with a capping drive motor 24, and the drive end gear of one capping drive motor 24 simultaneously meshes with the capping end gears 26 of four adjacent capping assemblies 25.

[0061] Specifically, the efficient power distribution is achieved by using one capping drive motor 24 to drive four adjacent capping assemblies 25. Through the meshing of the drive end gear and the four capping end gears 26, the rotational power of the capping drive motor 24 can be simultaneously transmitted to multiple capping assemblies 25. Similar to a central power source providing power to multiple surrounding work units, this reduces the number of capping drive motors 24 used, lowering equipment costs and energy consumption. The capping assemblies 25 are arranged in an M×N matrix, with one capping drive motor 24 configured for every four capping assemblies 25, resulting in a more compact and rational layout of the entire device. This layout allows for the placement of more capping assemblies 25 within a limited space, improving production efficiency. Here, M and N are positive integers and can be flexibly designed according to requirements.

[0062] Since one capping drive motor 24 drives four capping assemblies 25 simultaneously, as long as the rotational speed of the capping drive motor 24 is stable, the four capping assemblies 25 can rotate synchronously. This ensures that all capping assemblies 25 driven by the same capping drive motor 24 perform capping operations at the same speed and torque, thus improving the consistency of product quality.

[0063] See Figure 6 , Figure 7 and Figure 8In this embodiment, the batch capping mechanism III for cryopreservation tubes further includes a cap removal assembly 32. The cap removal assembly 32 includes a cap removal motor mounting plate 33, a cap removal drive motor 34, a first cap removal adapter plate 35, a second cap removal adapter plate 36, a cap removal plate body 37, and cap removal upper and lower guide rails 38. The cap removal motor mounting plate 33 is connected to the front of the batch capping mounting stand 21, and the cap removal drive motor 34 is connected to the cap removal motor mounting plate 33. The first cap removal adapter plate 35 is connected to the drive end of the cap removal drive motor 34, and the second cap removal adapter plate 36 is connected to the first cap removal adapter plate 35. The cap removal plate body 37 is connected to the lower end of the second cap removal adapter plate 36, and the capping head 30 is located below the cap removal plate body 37. The clutch shaft 29 passes through the cap removal plate body 37 and is inserted into the capping head 30. The cap removal upper and lower guide rails 38 are connected to the side of the batch capping mounting stand 21, and the second cap removal adapter plate 36 is connected to the cap removal upper and lower guide rails 38 through the cap removal upper and lower sliders 39.

[0064] Specifically, the cap removal motor mounting plate 33 is connected to the front of the batch capping mounting stand 21, providing a stable mounting base for the cap removal drive motor 34. This layout allows the cap removal drive motor 34 to be tightly integrated with the entire cryopreservation tube batch capping mechanism III, enhancing stability through the support structure of the batch capping mounting stand 21. The cap removal drive motor 34 is mounted on the cap removal motor mounting plate 33, providing power to the cap removal assembly 32. Starting from the drive end of the cap removal drive motor 34, power is transmitted sequentially through the first cap removal adapter plate 35 and the second cap removal adapter plate 36. The design of the first cap removal adapter plate 35 and the second cap removal adapter plate 36 helps to adjust the direction of power transmission, enabling the power to be accurately and effectively transmitted to the cap removal plate body 37.

[0065] The cap removal plate body 37 is connected to the lower end of the second cap removal adapter plate 36 and is positioned above the capping head 30. The clutch shaft 29 passes through the cap removal plate body 37 and is inserted into the capping head 30, creating conditions for the cap removal operation. When the cap removal drive motor 34 operates, it moves the cap removal plate body 37 via the first cap removal adapter plate 35 and the second cap removal adapter plate 36. The cap removal plate body 37 can apply force to the capping head 30 connected to the clutch shaft 29, thereby disengaging the capping head 30 from the cryopreservation tube cap and completing the cap removal function.

[0066] The cap removal guide rails 38 are connected to the side of the batch capping mounting stand 21, and the second cap removal adapter plate 36 is connected to it via the cap removal slider 39. This strictly limits the movement trajectory of the second cap removal adapter plate 36 and its connected components, ensuring that it can only move in the vertical direction. During the cap removal process, regardless of the power provided by the cap removal drive motor 34, the cap removal assembly 32 can move precisely up and down under the guidance of the cap removal guide rails 38, effectively avoiding swaying and deviation during movement, and greatly improving the stability and accuracy of the cap removal operation.

[0067] In summary, the cryopreservation tube rack in / out drive motor 10 of this utility model is fixed to the side of the central plate 3. The function of the cryopreservation tube rack in / out drive motor 10 is to provide power for the in / out movement of the cryopreservation tube rack by meshing the gear at the drive end with the cryopreservation tube rack in / out drive rack 11. The cryopreservation tube rack in / out drive rack 11 is fixed to the bottom of the cryopreservation tube rack tray 5, and the cryopreservation tube rack in / out transmission slide rail 12 is fixed to the bottom of the outer shell 1. It is connected to the cryopreservation tube rack tray 5 through the cryopreservation tube rack in / out transmission slider 13, which guides the in / out movement of the cryopreservation tube rack tray 5. The cryopreservation tube rack tray 5 has a transmission clearance strip hole 14. The drive end of the cryopreservation tube rack in / out drive motor 10 passes through the transmission clearance strip hole 14 and then meshes with the cryopreservation tube rack in / out drive rack 11 through the gear. A clearance gap 15 is formed between the cryopreservation tube rack in / out drive motor 10 and the upper end face of the cryopreservation tube rack tray 5. A transmission clearance slot 14 is formed on the cryopreservation tube rack tray 5. This design provides a channel for the drive end of the cryopreservation tube rack in / out drive motor 10 to mesh with the cryopreservation tube rack in / out drive rack 11. After the drive end of the cryopreservation tube rack in / out drive motor 10 passes through the transmission clearance slot 14, it meshes with the cryopreservation tube rack in / out drive rack 11 through gears to drive the cryopreservation tube rack tray 5. The clearance gap 15 formed between the upper end face of the cryopreservation tube rack in / out drive motor 10 and the cryopreservation tube rack tray 5 prevents interference between the cryopreservation tube rack tray 5 during operation and ensures the normal operation of the equipment. The lifting drive motor 7 of the capping lifting drive mechanism II is a dual-shaft electric motor, providing power for the lifting of the cryopreservation tube batch capping mechanism III. The first transmission idler wheel 16, the first tensioning wheel 17, and the second tensioning wheel 18 are connected to the side of the central plate 3, and the second transmission idler wheel 19 is located at the bottom of the outer shell 1. The reasonable positional distribution ensures the normal operation of the capping lifting drive mechanism II. The lifting transmission belt is connected at one end to the upper part of the transmission belt fixing seat 20, and at the other end, it passes over the first transmission idler pulley 16, the first tension pulley 17, the drive wheel of the lifting drive motor 7, the second tension pulley 18, and the second transmission idler pulley 19 before connecting to the lower part of the transmission belt fixing seat 20, forming a complete lifting transmission system. The capping drive motor 24 serves as the power source, generating rotational power when it starts. This power is transmitted to the capping assembly 25 via the motor shaft. Since the capping assembly 25 passes through the batch capping mounting top plate 22 and the batch capping transmission support plate 23, the rotational motion of the capping drive motor 24 can be effectively transmitted to all parts of the capping assembly 25, providing power for the capping operation. The capping assembly 25 begins to rotate under the drive of the capping drive motor 24, and the batch capping mounting stand 21 provides a support structure for the entire capping process. The batch capping mounting stand 21, with its upper part connected to the batch capping mounting top plate 22 and its inner middle part connected to the batch capping transmission support plate 23, together ensures that the capping assembly 25 rotates in a stable position. The power of the capping drive motor 24 is transmitted to the capping end gear 26 in the capping assembly 25 through the drive end gear.This gear meshing method ensures efficient power transmission and allows for appropriate conversion of speed and torque. The capping end gear 26 is connected to the upper end of the gear drive shaft 27. When the capping end gear 26 rotates, the gear drive shaft 27 also rotates. The lower part of the gear drive shaft 27 passes through the batch capping mounting top plate 22 and connects to the top of the gear body 28, thus transmitting power from the capping end gear 26 above the top plate to the gear body 28. The gear body 28 engages with the top clutch groove 31 of the clutch shaft 29. This clutch structure allows for clutch control of the capping assembly 25 during operation. For example, when it is necessary to replace the capping head 30 or perform equipment debugging, the capping head 30 can be separated from the power unit by controlling the clutch structure. The clutch shaft 29 passes through the batch capping transmission support plate 23, ensuring the stability of the clutch shaft 29 during rotation. The position of the clutch shaft 29 is accurately fixed in the support structure of the device. Since the capping head 30 is connected to the lower end of the clutch shaft 29, when power is transmitted to the capping head 30, the capping head 30 can perform the capping operation on the cryopreservation tube cap. The specific structure of the capping head 30 can vary depending on the type and size of the cryopreservation tube cap. For example, for round cryopreservation tube caps, the capping head 30 has a groove that matches the edge of the cryopreservation tube cap or a rubber ring with high friction to ensure that it can effectively grip the cryopreservation tube cap. The cap removal motor mounting plate 33 is connected to the front of the batch capping mounting stand 21, providing a stable mounting base for the cap removal drive motor 34. This layout allows the cap removal drive motor 34 to be tightly integrated with the entire cryopreservation tube batch capping mechanism III, and the stability is enhanced by the support structure of the batch capping mounting stand 21. The cap removal drive motor 34 is mounted on the cap removal motor mounting plate 33 and provides power to the cap removal assembly 32. Starting from the drive end of the cap removal drive motor 34, the power is transmitted sequentially through the first cap removal adapter plate 35 and the second cap removal adapter plate 36. The design of the first cap removal adapter plate 35 and the second cap removal adapter plate 36 helps to adjust the direction of power transmission, enabling power to be accurately and effectively transmitted to the cap removal plate body 37. The cap removal plate body 37 is connected to the lower end of the second cap removal adapter plate 36 and is positioned above the capping head 30. The clutch shaft 29 passes through the cap removal plate body 37 and is inserted into the capping head 30, creating conditions for the cap removal operation. When the cap removal drive motor 34 operates, it moves the cap removal plate body 37 through the first cap removal adapter plate 35 and the second cap removal adapter plate 36. The cap removal plate body 37 can apply force to the capping head 30 connected to the clutch shaft 29, thereby disengaging the capping head 30 from the cryopreservation tube cap and completing the cap removal function.This invention allows for the simultaneous opening of multiple cryovials in a short period of time, enabling rapid acquisition of the required samples and thus accelerating the experimental or testing process. Furthermore, it allows for the batch opening of a group of tissue sample cryovials, ensuring that all samples are exposed to the same environmental conditions at the same time, thereby better controlling experimental variables and making experimental results more comparable and accurate. This not only improves efficiency but also reduces errors caused by manual operation, making the entire experimental process more standardized and precise.

[0068] Although the present invention has been described in detail above with general descriptions and specific embodiments, some modifications or improvements can be made to it, which will be obvious to those skilled in the art. Therefore, all such modifications or improvements made without departing from the spirit of the present invention fall within the scope of protection claimed by the present invention.

Claims

1. A batch capping device for cryopreservation tubes, characterized in that, The device includes an outer shell (1), on the side of which a cryopreservation tube rack inlet / outlet (2) is formed, and inside the outer shell (1) a central plate (3) is provided, with a cryopreservation tube rack drive clearance opening (4) formed at the bottom of the central plate (3); it also includes a cryopreservation tube rack inlet / outlet drive mechanism (I), a capping and lifting drive mechanism (II), and a cryopreservation tube batch capping mechanism (III); The cryopreservation tube rack entry and exit drive mechanism (I) is located at the bottom inside the outer shell (1). The cryopreservation tube rack entry and exit drive mechanism (I) includes a cryopreservation tube rack tray (5). The cryopreservation tube rack tray (5) passes through the cryopreservation tube rack drive clearance opening (4). The end of the cryopreservation tube rack tray (5) forms a cryopreservation tube rack placement groove (6). The cap lifting drive mechanism (II) includes a lifting drive motor (7) and a lifting slide rail (9). The lifting drive motor (7) is fixed on one side of the central plate (3), and the lifting slide rail (9) is fixed on the other side of the central plate (3). The cryopreservation tube batch capping mechanism (III) is connected to the lifting slide rail (9) via the lifting slider (8), and the cryopreservation tube rack entry and exit drive mechanism (I) transfers the cryopreservation tube rack in the cryopreservation tube rack placement slot (6) to the bottom of the cryopreservation tube batch capping mechanism (III). The lifting drive motor (7) is also connected to the cryopreservation tube batch capping mechanism (III) via a lifting transmission belt. The lifting drive motor (7) drives the cryopreservation tube batch capping mechanism (III) to move up and down along the lifting slide rail (9) via the lifting transmission belt. The cryopreservation tube batch capping mechanism (III) moves downward to align with and unscrew the caps of the cryopreservation tubes placed in the cryopreservation tube rack on the cryopreservation tube rack placement slot (6).

2. The batch capping device for cryopreservation tubes according to claim 1, characterized in that, The cryopreservation tube rack entry and exit drive mechanism (I) further includes a cryopreservation tube rack entry and exit drive motor (10), a cryopreservation tube rack entry and exit drive rack (11), a cryopreservation tube rack entry and exit transmission slide rail (12), and a cryopreservation tube rack entry and exit transmission slider (13). The cryopreservation tube rack in / out drive motor (10) is fixed to the side of the central plate (3), and the cryopreservation tube rack in / out drive rack (11) is fixed to the bottom of the cryopreservation tube rack tray (5). The drive end of the cryopreservation tube rack in / out drive motor (10) meshes with the cryopreservation tube rack in / out drive rack (11) through gears. The cryopreservation tube rack in / out transmission slide rail (12) is fixed to the bottom of the outer shell (1), and the cryopreservation tube rack in / out transmission slide rail (12) is connected to the cryopreservation tube rack tray (5) through the cryopreservation tube rack in / out transmission slider (13).

3. The batch capping device for cryopreservation tubes according to claim 2, characterized in that, The cryopreservation tube rack tray (5) has a transmission clearance strip hole (14). The drive end of the cryopreservation tube rack in-out drive motor (10) passes through the transmission clearance strip hole (14) and then meshes with the cryopreservation tube rack in-out drive rack (11) through a gear. A clearance gap (15) is formed between the drive motor (10) for entering and exiting the cryopreservation tube rack and the upper surface of the cryopreservation tube rack tray (5).

4. The batch capping device for cryopreservation tubes according to claim 1, characterized in that, The lifting drive motor (7) of the cap lifting drive mechanism (II) is a dual-shaft electric motor; the cap lifting drive mechanism (II) also includes a first transmission idler wheel (16), a first tensioning wheel (17), a second tensioning wheel (18), a second transmission idler wheel (19), and a transmission belt fixing seat (20); The first drive idler wheel (16), the first tensioner wheel (17), and the second tensioner wheel (18) are all connected to the side of the neutral plate (3), and the second drive idler wheel (19) is located at the bottom of the outer shell (1); One end of the lifting transmission belt is connected to the upper part of the transmission belt fixing seat (20), and the other end of the lifting transmission belt passes around the first transmission idler wheel (16), the first tensioner wheel (17), the drive wheel of the lifting drive motor (7), the second tensioner wheel (18), and the second transmission idler wheel (19) and then connects to the lower part of the transmission belt fixing seat (20).

5. A batch capping device for cryopreservation tubes according to claim 4, characterized in that, The batch capping mechanism (III) for cryopreservation tubes includes a batch capping mounting stand (21), a batch capping mounting top plate (22), a batch capping transmission support plate (23), a capping drive motor (24), and a capping assembly (25); The upper part of the batch capping mounting stand (21) is connected to the batch capping mounting top plate (22). The transmission belt fixing seat (20) is connected to the outer side of the top of the batch capping mounting stand (21). The batch capping transmission support plate (23) is connected to the inner side of the middle part of the batch capping mounting stand (21). The batch capping transmission support plate (23) is located below the batch capping mounting stand (21). The capping drive motor (24) is located at the upper end of the batch capping mounting top plate (22). The capping drive motor (24) is connected to the capping assembly (25). The capping assembly (25) passes through the batch capping mounting top plate (22) and the batch capping transmission support plate (23).

6. The batch capping device for cryopreservation tubes according to claim 5, characterized in that, The capping assembly (25) includes a capping end gear (26), a gear drive shaft (27), a gear body (28), a clutch shaft (29), and a capping head (30); The capping end gear (26) meshes with the drive end gear of the capping drive motor (24). The upper end of the toothed drive shaft (27) is connected to the capping end gear (26). The lower part of the toothed drive shaft (27) passes through the batch capping mounting top plate (22) and is connected to the top of the toothed body (28). The toothed body (28) and the top clutch groove (31) of the clutch shaft (29) are engaged. The clutch shaft (29) passes through the batch capping drive support plate (23). The capping head (30) is connected to the lower end of the clutch shaft (29).

7. A batch capping device for cryopreservation tubes according to claim 6, characterized in that, The number of the capping assemblies (25) is M×N, where M is the number of columns and N is the number of rows; Each of the four capping assemblies (25) is equipped with a capping drive motor (24), and the drive end gear of one capping drive motor (24) simultaneously meshes with the capping end gears (26) of the four adjacent capping assemblies (25).

8. A batch capping device for cryopreservation tubes according to claim 6, characterized in that, The batch capping mechanism (III) for cryopreservation tubes also includes a cap removal assembly (32); the cap removal assembly (32) includes a cap removal motor mounting plate (33), a cap removal drive motor (34), a first cap removal adapter plate (35), a second cap removal adapter plate (36), a cap removal plate body (37), and cap removal upper and lower guide rails (38); The cap removal motor mounting plate (33) is connected to the front of the batch cap mounting stand (21), and the cap removal drive motor (34) is connected to the cap removal motor mounting plate (33); the first cap removal adapter plate (35) is connected to the drive end of the cap removal drive motor (34), and the second cap removal adapter plate (36) is connected to the first cap removal adapter plate (35); The lower end of the cover-removing plate body (37) is connected to the second cover-removing adapter plate (36), the capping head (30) is located below the cover-removing plate body (37), and the clutch shaft (29) passes through the cover-removing plate body (37) and is inserted into the capping head (30). The cap removal upper and lower guide rails (38) are connected to the side of the batch cap mounting stand (21), and the second cap removal adapter plate (36) is connected to the cap removal upper and lower guide rails (38) through the cap removal upper and lower sliders (39).