Rapid pathological slide preparation device
By designing a rapid pathological slide preparation device, and utilizing lifting and liquid storage cleaning devices to achieve automated staining, the problem of low efficiency in manual operation is solved, staining speed is increased and the risk of contamination is reduced.
Patent Information
- Application Number
- CN202520297071.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-24
- Publication Date
- 2026-02-10
- Estimated Expiration
- 2035-02-24
AI Technical Summary
In the process of preparing pathological slides, staining requires manual operation, which leads to low efficiency and is prone to human error.
A rapid pathological slide preparation device was designed, which includes a lifting device, a liquid storage device, and a cleaning device. The slides are automatically stained and cleaned in the liquid storage bottle by a motor, reducing manual intervention.
Automated dyeing has been achieved, which has improved efficiency, reduced human error, and lowered the risk of contamination during the dyeing process.
Smart Images

Figure CN223897161U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to pathological sectioning and staining technical field, concretely is a set of fast pathological sectioning device. BACKGROUND
[0002] Pathological sectioning is a kind of technology for medical diagnosis and research, which makes tissue sample into thin slice and stains to observe cell and tissue structure under microscope, and common pathological sectioning and staining method has HE staining method, immunohistochemical staining, Masson staining, PAS staining, bismarck staining etc., HE staining is the most widely used staining technology in histopathology, can make different tissue components to be stained into different degrees of color, makes it easy to observe, this method can be used to any fixed tissue and section of embedding method, hematoxylin is a kind of basic dye, can make the alkaliophilic substance in tissue to be dyed into blue, such as chromatin in cell nucleus etc., eosin is a kind of acid dye, can make the acidophilic substance in tissue to be dyed into red, such as the cytoplasm of most cells, nucleolus etc. in H.E stained section are all red, and the steps include dewaxing to water, hematoxylin dyeing cell nucleus, hydrochloric acid ethanol differentiation for several seconds, ammonia water returns blue, eosin dyeing cytoplasm, dehydration and mounting and microscope examination and image acquisition analysis etc.
[0003] In the prior art, the tissue on the slide needs to be stained during pathological sectioning, and the staining process is generally manually operated, in order to speed up the staining steps and reduce human errors, we propose a set of fast pathological sectioning device. UTILITY MODEL CONTENT
[0004] The utility model aims at providing a set of fast pathological sectioning device to solve the problems existing in the prior art proposed in the above background technology.
[0005] In order to achieve the above object, the utility model adopts the following technical scheme:
[0006] A set of fast pathological sectioning device, including the box, the top of the box is provided with the top cover, the top cover and the box are connected through the lifting device, the lower end of the top cover is provided with the through slot, the through slot is provided with the clamping seat, the clamping seat is provided with the slide, the box is provided with the rotating disc, the rotating disc is provided with the liquid storage device on the side wall, the rotating disc is provided with the cleaning device on the side wall, the inner bottom of the box is fixedly connected with the motor at the corresponding position, and the output shaft of the motor is fixedly connected with the rotating disc.
[0007] Preferably, the clamping seat is composed of a first side plate and a second side plate, a clamping seat is fixedly connected to the side wall of the first side plate, an electric telescopic rod is fixedly connected to the inner wall of the through groove at the corresponding position, the elongated end of the electric telescopic rod is fixedly connected to the side wall of the clamping seat, a groove is penetratingly arranged at the side wall of the clamping seat, a connecting column is fixedly connected to the side wall of the second side plate, a spring is elastically connected to the port of the connecting column, the other end of the spring is elastically connected to the inner bottom of the groove, a spray head is fixedly connected to the inner wall of the first side plate, a water inlet pipe is fixedly and communicatively connected to the spray head, clamping grooves are penetratingly arranged at the opposite side walls between the first side plate and the second side plate, and the slide glass is clamped in the two clamping grooves.
[0008] Preferably, the lifting device comprises a first fixed plate fixedly connected to the side wall of the top cover, a second fixed plate fixedly connected to the side wall of the box at the corresponding position, and two hydraulic rods fixedly connected between the first fixed plate and the second fixed plate.
[0009] Preferably, the liquid storage device comprises a plurality of fixed grooves penetratingly arranged on the side wall of the rotating disc, and a plurality of liquid storage bottles are sleeved in the fixed grooves, wherein the positions of the liquid storage bottles correspond to the positions of the clamping seats in an up-down manner.
[0010] Preferably, the cleaning device comprises an opening penetratingly arranged on the side wall of the rotating disc, and a drain pipe penetratingly and fixedly communicated with the side wall of the box at the corresponding position.
[0011] Preferably, the clamping seat can completely enter the through groove.
[0012] Compared with the prior art, the device has the following beneficial effects:
[0013] In the device, the lifting device, the liquid storage device and the cleaning device are matched with each other, the device is used for dyeing in pathological sectioning, reagents used for dyeing are added into the liquid storage bottles, the slide glass is clamped on the clamping seat, the top cover is closed, the motor and the electric telescopic rod are sequentially moved, the clamping seat is respectively immersed into the liquid storage bottles for dyeing and differentiation, the rotating disc can be rotated to the opening for water washing by spraying clean water through the spray head in the gap, the rotating disc can be rotated to the opening without affecting other liquid storage bottles during water washing, the device is reasonable in operation design, can replace manual dyeing, reduces human errors, accelerates the dyeing speed, reduces pollution, and is convenient for operators to use. BRIEF DESCRIPTION OF DRAWINGS
[0014] Fig. 1 The device is a set of quick pathological sectioning device structure schematic view;
[0015] Fig. 2 The device is a set of quick pathological sectioning device clamping seat structure expansion schematic view;
[0016] Fig. 3 This invention presents a schematic diagram of the rotating disk and related structures of a rapid pathological slide preparation device.
[0017] In the diagram: 1. Box body, 2. Top cover, 3. First fixing plate, 4. Clamping seat, 5. Hydraulic rod, 6. Second fixing plate, 7. Drain pipe, 8. Inlet pipe, 9. Nozzle, 10. Electric telescopic rod, 11. First side plate, 12. Glass slide, 13. Spring, 14. Second side plate, 15. Rotating disk, 16. Liquid storage bottle, 17. Opening, 18. Motor. Detailed Implementation
[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0019] Reference Figs. 1-3 A rapid pathological slide preparation device includes a box body 1, a top cover 2 at the top of the box body 1, and a lifting device connecting the top cover 2 and the box body 1. The lifting device includes a first fixing plate 3 fixedly connected to the side wall of the top cover 2, and a second fixing plate 6 fixedly connected to the side wall of the box body 1 at the corresponding position. Two hydraulic rods 5 are fixedly connected between the first fixing plate 3 and the second fixing plate 6.
[0020] The top cover 2 has a through groove at its lower end, and a clamping seat 4 is provided in the through groove. The clamping seat 4 clamps a glass slide 12. The clamping seat 4 is composed of a first side plate 11 and a second side plate 14. A card holder is fixedly connected to the side wall of the first side plate 11. An electric telescopic rod 10 is fixedly connected to the inner wall of the through groove at the corresponding position. The extended end of the electric telescopic rod 10 is fixedly connected to the side wall of the card holder. A groove is provided through the side wall of the card holder. A connecting post is fixedly connected to the side wall of the second side plate 14. A spring 13 is elastically connected to the end of the connecting post. The other end of the spring 13 is elastically connected to the bottom of the groove. A nozzle 9 is fixedly connected to the inner wall of the first side plate 11. A water inlet pipe 8 is fixedly connected to the nozzle 9. Slots are provided through the opposite side walls of the first side plate 11 and the second side plate 14. The glass slide 12 is clamped in the two slots.
[0021] The housing 1 contains a rotating disk 15, and a liquid storage device is installed through the side wall of the rotating disk 15. The liquid storage device includes multiple fixed slots installed through the side wall of the rotating disk 15, and a liquid storage bottle 16 is fitted in each of the multiple fixed slots. The positions of the multiple liquid storage bottles 16 correspond vertically to the positions of the clamping seats 4. The number of liquid storage bottles 16 is multiple, not just three. The specific number can be determined according to the actual use. A cleaning device is installed through the side wall of the rotating disk 15. The cleaning device includes an opening 17 installed through the side wall of the rotating disk 15. A drain pipe 7 is fixedly connected through the side wall of the housing 1 at the corresponding position. A motor 18 is fixedly connected to the bottom of the housing 1 at the corresponding position. The output shaft of the motor 18 is fixedly connected to the rotating disk 15.
[0022] Specifically, the clamping seat 4 can be fully inserted into the through groove.
[0023] In this utility model, the operator can add hematoxylin dye, hydrochloric acid ethanol solution, weak alkaline solution, eosin dye, etc. to each of the storage bottles 16 respectively. The second side plate 14 on one side is pulled to insert the glass slide 12 into the two slots. Then, the top cover 2 is driven down by the two hydraulic rods 5, so that the clamping seat 4 enters the box 1.
[0024] First, the clamping seat 4, carrying the glass slide 12, is immersed in the hematoxylin staining solution for several minutes, causing the chromatin in the cell nucleus and the nucleic acid in the cytoplasm to turn purple-blue. Then, the electric telescopic rod 10 moves the glass slide 12 back into the channel. Next, the motor 18 drives the rotating disk 15 to rotate to the opening 17, and the glass slide 12 falls back down. The water inlet pipe 8 is controlled by the relevant control equipment in the prior art to spray cleaning water through the nozzle 9 to wash away the residual staining solution. Then, the glass slide 12 is raised, and the rotating disk 15 rotates to the hydrochloric acid ethanol solution position. Place the slide 12 in a solution and immerse it in the solution. The cytoplasm and connective tissue will be destained by the hydrochloric acid-ethanol differentiation, leaving only the nucleus stained. Repeat the above operation, rinsing off the excess solution with clean water and then immersing the slide 12 in a weakly alkaline solution to turn it blue again, making the cell nucleus blue. Repeat the above water rinsing operation to remove the excess solution and then immerse the slide 12 in the corresponding eosin staining solution to stain the components in the cytoplasm and extracellular matrix red. Then remove the slide 12 and proceed to the next step.
[0025] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.
Claims
1. A rapid pathological slide preparation device, comprising a housing (1), characterized in that, A top cover (2) is provided at the top of the box (1). The top cover (2) is connected to the box (1) through a lifting device. A through groove is provided at the lower end of the top cover (2). A clamping seat (4) is provided in the through groove. A glass slide (12) is clamped in the clamping seat (4). A rotating disk (15) is provided inside the box (1). A liquid storage device is provided through the side wall of the rotating disk (15). A cleaning device is provided through the side wall of the rotating disk (15). A motor (18) is fixedly connected to the bottom of the box (1) at the corresponding position. The output shaft of the motor (18) is fixedly connected to the rotating disk (15).
2. The rapid pathological slide preparation device according to claim 1, characterized in that, The clamping seat (4) is composed of a first side plate (11) and a second side plate (14). A card seat is fixedly connected to the side wall of the first side plate (11), and an electric telescopic rod (10) is fixedly connected to the inner wall of the through groove at the corresponding position. The extended end of the electric telescopic rod (10) is fixedly connected to the side wall of the card seat. A groove is provided through the side wall of the card seat. A connecting column is fixedly connected to the side wall of the second side plate (14). A spring (13) is elastically connected to the end of the connecting column. The other end of the spring (13) is elastically connected to the bottom of the groove. A nozzle (9) is fixedly connected to the inner wall of the first side plate (11). A water inlet pipe (8) is fixedly connected to the nozzle (9). A slot is provided through the opposite side walls of the first side plate (11) and the second side plate (14). The glass slide (12) is snapped into the two slots.
3. The rapid pathological slide preparation device according to claim 1, characterized in that, The lifting device includes a first fixing plate (3) fixedly connected to the side wall of the top cover (2), and a second fixing plate (6) fixedly connected to the side wall of the box (1) at the corresponding position. Two hydraulic rods (5) are fixedly connected between the first fixing plate (3) and the second fixing plate (6).
4. The rapid pathological slide preparation device according to claim 1, characterized in that, The liquid storage device includes multiple fixed grooves that are installed through the side wall of the rotating disk (15), and a liquid storage bottle (16) is fitted in each of the multiple fixed grooves. The positions of the multiple liquid storage bottles (16) correspond vertically to the positions of the clamping seats (4).
5. The rapid pathological slide preparation device according to claim 1, characterized in that, The cleaning device includes an opening (17) through the side wall of the rotating disk (15), and a drain pipe (7) through and fixedly connected to the side wall of the box (1) at the corresponding position.
6. The rapid pathological slide preparation device according to claim 1, characterized in that, The clamping seat (4) can be fully inserted into the through groove.