Solid-phase polypeptide synthesis device

Abstract

The utility model discloses a solid-phase polypeptide synthesis device and relates to the field of polypeptide synthesis. The solid-phase polypeptide synthesis device comprises a synthesis heating box, a bearing plate is arranged on the periphery of the interior of the synthesis heating box, a perforated limiting plate is arranged above the bearing plate, a supporting block is fixedly connected to one side of the bearing plate, and a shell, an adjusting assembly and a rotating assembly are fixedly connected to the upper end of the supporting block; the adjusting assembly is arranged in the shell and used for driving the trepanning limiting plate to move up and down, the rotating assembly is located on the synthesis heating box and used for driving the bearing plate and the trepanning limiting plate to rotate, and the adjusting assembly comprises a lead screw. The technical problems that according to an existing synthesis device, the placement height cannot be adjusted according to the sizes of test tubes, synthesis reaction cannot be conducted on the test tubes of different sizes at a time, the test tubes are inconvenient to take, and people are inconvenient to use are solved.

Description

TECHNICAL FIELD

[0001] The utility model relates to polypeptide synthesis field especially, it relates to a solid -phase polypeptide synthesis device. BACKGROUND

[0002] Polypeptide is a kind of biological activity material related to the function of various cells in organism, is the general term of biological activity material involving the function of various cells in organism, is often applied in functional analysis, antibody research, especially drug research and development etc., polypeptide synthesis device refers to the equipment for synthesizing polypeptide, most polypeptides are loaded in multiple test tubes, test tube is placed on test tube rack, test tube rack is placed in synthesis device to carry out polypeptide synthesis reaction.

[0003] However, the prior art has some problems: the existing synthesis device cannot adjust the placement height according to the size of test tube, cannot carry out synthesis reaction on test tubes of different sizes at a time, and is not convenient for taking test tubes, so it is not convenient for people to use, therefore it is necessary to provide a solid-phase polypeptide synthesis device to solve the above technical problems. UTILITY MODEL CONTENT

[0004] The utility model provides a solid-phase polypeptide synthesis device, solve the existing synthesis device, cannot adjust the placement height according to the size of test tube, cannot carry out synthesis reaction on test tubes of different sizes at a time, and also inconvenient for test tube to take, the technical problem of inconvenient for people to use.

[0005] To solve the above technical problems, the utility model provides a solid-phase polypeptide synthesis device, which comprises:

[0006] The synthesis heating box is internally provided with a bearing plate around, the upper portion of the bearing plate is provided with an opening limiting plate, one side of the bearing plate is fixedly connected with a supporting block, and the upper end of the supporting block is fixedly connected with a shell.

[0007] The adjusting assembly is in the shell, and the adjusting assembly is used to drive the opening limiting plate to move up and down, and the rotating assembly is located on the synthesis heating box, and the rotating assembly is used to drive the bearing plate and the opening limiting plate to rotate.

[0008] Preferably, the adjusting assembly comprises a lead screw, the upper end of the lead screw penetrates to the upper end of the shell and is fixedly connected with a rotating wheel, the surface of the lead screw is threadedly connected with a threaded block, the lower end of the lead screw is sleeved with a first bearing seat, and the lower end of the first bearing seat is fixedly connected with the lower end in the shell.

[0009] Preferably, the threaded block is fixedly connected with a fixed column, one end of the fixed column extends to the outside of the shell and is fixedly connected with the opening limiting plate.

[0010] Preferably, the rotating assembly comprises a stepping motor, the output of the stepping motor is connected to the inside of the synthetic heating box and fixedly connected with a rectangular beam, the surface of the rectangular beam is fixedly connected with one end of a bearing plate, the lower end of the rectangular beam is fixedly connected with a rotating shaft, the lower end of the rotating shaft is sleeved with a second bearing seat, and the lower end of the second bearing seat is fixedly connected with the lower end of the inside of the synthetic heating box.

[0011] Preferably, the front surface of the synthetic heating box is hingedly connected with a box door through a hinge, and the lower end of the synthetic heating box is fixedly connected with a stand column.

[0012] Preferably, one side of the opening limiting plate is fixedly connected with a sliding block, the inside of the sliding block is slidably connected with a sliding rod, the lower end of the sliding rod is fixedly connected with a fixed block, and the fixed block is fixedly connected with the bearing plate.

[0013] Compared with the related art, the solid-phase polypeptide synthesis device has the following beneficial effects:

[0014] The solid-phase polypeptide synthesis device has the following beneficial effects: the first bearing seat and the second bearing seat are matched with each other, the rotating shaft and the screw rod are stably rotated during use, and the problem that the rotating shaft and the screw rod are easily shaken during use is solved.

[0015] The solid-phase polypeptide synthesis device has the following beneficial effects: the stepping motor, the rectangular beam and the rotating shaft are matched with each other, the bearing plate and the opening limiting plate are easily rotated during use, and the test tube on the opening limiting plate is easily taken.

[0016] The solid-phase polypeptide synthesis device has the following beneficial effects: the sliding block and the sliding rod are matched with each other, the opening limiting plate is stably moved up and down during use, and the problem that the opening limiting plate is easily shaken during use is solved. BRIEF DESCRIPTION OF DRAWINGS

[0017] Fig. 1 The solid-phase polypeptide synthesis device has the following beneficial effects: the sliding block and the sliding rod are matched with each other, the opening limiting plate is stably moved up and down during use, and the problem that the opening limiting plate is easily shaken during use is solved.

[0018] Fig. 2 The solid-phase polypeptide synthesis device has the following beneficial effects: the sliding block and the sliding rod are matched with each other, the opening limiting plate is stably moved up and down during use, and the problem that the opening limiting plate is easily shaken during use is solved.

[0019] Fig. 3 The solid-phase polypeptide synthesis device has the following beneficial effects: the sliding block and the sliding rod are matched with each other, the opening limiting plate is stably moved up and down during use, and the problem that the opening limiting plate is easily shaken during use is solved.

[0020] The figure label: 1, synthesis heating box; 2, bearing plate; 3, opening limiting plate; 4, support block; 5, shell; 6, adjusting assembly; 61, lead screw; 62, rotating wheel; 63, threaded block; 64, fixed column; 7, rotating assembly; 71, stepper motor; 72, rectangular beam; 73, rotating shaft; 8, box door; 9, stand column; 10, sliding block; 11, slide rod; 12, fixed block. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model.

[0022] Embodiment one:

[0023] Please refer to Figs. 1-3 The utility model provides a kind of technical solutions: a kind of solid-phase polypeptide synthesis device, comprising: synthesis heating box 1, synthesis heating box 1 inside the four around is provided with bearing plate 2, the upper portion of bearing plate 2 is provided with opening limiting plate 3, the side of bearing plate 2 is fixedly connected with support block 4, the upper end of support block 4 is fixedly connected with shell 5, adjusting assembly 6 and rotating assembly 7, adjusting assembly 6 is in shell 5, adjusting assembly 6 is used to drive the up-down movement of opening limiting plate 3, rotating assembly 7 is located on synthesis heating box 1, and rotating assembly 7 is used to drive the rotation of bearing plate 2 and opening limiting plate 3.

[0024] In the embodiment, first rotating wheel 62 is rotated, rotating wheel 62 is driven by first bearing seat to start rotating lead screw 61, and lead screw 61 is driven to move threaded block 63, threaded block 63 is driven to move fixed column 64, fixed column 64 is driven to move opening limiting plate 3, opening limiting plate 3 is driven to slide sliding block 10 on slide rod 11, so that the height of opening limiting plate 3 is moved to specified position, then test tube is inserted into opening limiting plate 3.

[0025] Embodiment two:

[0026] Please refer to Figs. 1-3As shown, on the basis of embodiment one, the utility model provides a technical scheme: adjusting assembly 6 includes screw rod 61, the upper end of screw rod 61 is penetrated to the upper end of shell 5 and is fixedly connected with rotating wheel 62, the surface of screw rod 61 is threadedly connected with threaded block 63, the lower end of screw rod 61 is sleeved with first bearing seat, and the lower end of first bearing seat is fixedly connected with the lower end inside shell 5, fixed column 64 is fixedly connected on threaded block 63, and one end of fixed column 64 extends to the outside of shell 5 and is fixedly connected with aperture limiting plate 3, rotating assembly 7 includes step motor 71, the output of step motor 71 is penetrated to the inside of synthetic heating box 1 and is fixedly connected with rectangular beam 72, and the periphery of the surface of rectangular beam 72 is fixedly connected with one end of bearing plate 2, the lower end of rectangular beam 72 is fixedly connected with rotating shaft 73, the lower end of rotating shaft 73 is sleeved with second bearing seat, and the lower end of second bearing seat is fixedly connected with the lower end inside synthetic heating box 1, the front of synthetic heating box 1 is hingedly connected with box door 8, and the periphery of the lower end of synthetic heating box 1 is fixedly connected with stand 9, one side of aperture limiting plate 3 is fixedly connected with sliding block 10, sliding block 10 is slidably connected with slide rod 11 inside, the lower end of slide rod 11 is fixedly connected with fixed block 12, and fixed block 12 is fixedly connected with bearing plate 2.

[0027] In the embodiment, the upper end of the test tube is in contact with the upper end of the bearing plate 2, and when it is necessary to take the test tube of different heights, the step motor 71 drives the rectangular beam 72 to start rotating, the rectangular beam 72 rotates on the second bearing seat through the rotating shaft 73, so that the rectangular beam 72 drives the bearing plate 2 and the aperture limiting plate 3 to rotate to the specified position, thereby facilitating the taking of the test tube.

[0028] The working principle of the solid-phase polypeptide synthesis device is as follows:

[0029] The first innovation point implementation step is as follows:

[0030] Step 1: first rotate the rotating wheel 62, the rotating wheel 62 drives the screw rod 61 to start rotating through the first bearing seat, the screw rod 61 drives the threaded block 63 to start moving, the threaded block 63 drives the fixed column 64 to start moving, and the fixed column 64 drives the aperture limiting plate 3 to start moving.

[0031] Step 2: the aperture limiting plate 3 drives the sliding block 10 to slide on the slide rod 11, so that the height of the aperture limiting plate 3 is moved to the specified position, and then the test tube is inserted into the aperture limiting plate 3.

[0032] The second innovation point implementation step is as follows:

[0033] Step 1: the upper end of the test tube is in contact with the upper end of the bearing plate 2, and when it is necessary to take the test tube of different heights, the step motor 71 drives the rectangular beam 72 to start rotating.

[0034] Second step: the rectangular beam 72 rotates on the second bearing seat through the rotating shaft 73, so that the rectangular beam 72 drives the bearing plate 2 and the opening limiting plate 3 to rotate to a specified position, and the test tube is convenient to take.

[0035] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A solid phase polypeptide synthesis apparatus, characterized by: Include: Synthetic heating box (1), the periphery of the inside of the synthetic heating box (1) is provided with a bearing plate (2), the upper side of the bearing plate (2) is provided with an opening limiting plate (3), one side of the bearing plate (2) is fixedly connected with a supporting block (4), the upper end of the supporting block (4) is fixedly connected with a shell (5); Adjusting assembly (6) and rotating assembly (7), the adjusting assembly (6) is in the shell (5), the adjusting assembly (6) is used for driving the up and down movement of the opening limiting plate (3), the rotating assembly (7) is located on the synthetic heating box (1), and the rotating assembly (7) is used for driving the rotation of the bearing plate (2) and the opening limiting plate (3).

2. A solid phase polypeptide synthesis device according to claim 1, wherein, The adjusting assembly (6) comprises a lead screw (61), the upper end of the lead screw (61) penetrates to the upper end of the shell (5) and is fixedly connected with a rotating wheel (62), the surface of the lead screw (61) is threadedly connected with a threaded block (63), the lower end of the lead screw (61) is sleeved with a first bearing seat, and the lower end of the first bearing seat is fixedly connected with the lower end of the inside of the shell (5).

3. A solid phase polypeptide synthesis device according to claim 2, wherein, The threaded block (63) is fixedly connected with a fixed column (64), one end of the fixed column (64) extends to the outside of the shell (5) and is fixedly connected with the opening limiting plate (3).

4. The apparatus of claim 1 wherein, The rotating assembly (7) comprises a stepping motor (71), the output of the stepping motor (71) penetrates to the inside of the synthetic heating box (1) and is fixedly connected with a rectangular beam (72), one end of the bearing plate (2) is fixedly connected with the surface of the rectangular beam (72), the lower end of the rectangular beam (72) is fixedly connected with a rotating shaft (73), the lower end of the rotating shaft (73) is sleeved with a second bearing seat, and the lower end of the second bearing seat is fixedly connected with the lower end of the inside of the synthetic heating box (1).

5. The apparatus of claim 1 wherein, The front of the synthetic heating box (1) is hinged with a box door (8) through a hinge, and the periphery of the lower end of the synthetic heating box (1) is fixedly connected with a stand column (9).

6. The apparatus of claim 1 wherein, One side of the opening limiting plate (3) is fixedly connected with a sliding block (10), the inside of the sliding block (10) is slidably connected with a sliding rod (11), the lower end of the sliding rod (11) is fixedly connected with a fixed block (12), and the fixed block (12) is fixedly connected with the bearing plate (2).

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