Reaction kettle for irinotecan hydrochloride

Abstract

The utility model provides a reaction kettle for irinotecan hydrochloride, which relates to the technical field of reaction kettles, and comprises a reaction kettle body, a top cover is arranged at the top of the reaction kettle body, a rotating rod is arranged in the reaction kettle body, a spiral blade is sleeved and fixedly connected on the surface of the rotating rod, and the spiral blade is arranged on the top of the reaction kettle body. And arc plates are symmetrically and fixedly connected to the positions, close to the top, of the surface of the rotating rod, inclined plates are fixedly connected to the inner arc walls of the arc plates, a supporting disc is fixedly connected to the bottom of the rotating rod, and U-shaped pieces are fixedly connected to the outer arc surface of the top cover at equal intervals. The driving motor drives the rotating rod to rotate, the rotating rod rotates to drive the arc plate and the inclined plate to rotate, the effect of conveying raw materials on the edge of the reaction kettle body to the center can be achieved, meanwhile, the rotating rod rotates to drive the spiral blades to rotate, and the effect of upwards conveying the raw materials at the bottom and the center can be achieved; therefore, the effect of improving the stirring efficiency and uniformity can be achieved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of reaction kettle, especially relates to a reaction kettle for hydrochloric acid irinotecan. BACKGROUND

[0002] Hydrochloric acid irinotecan is an oral drug for treating non-small cell lung cancer (NSCLC). It belongs to a class of drugs called tyrosine kinase inhibitors, which inhibit the activation of epidermal growth factor receptor (EGFR) on the surface of tumor cells, thereby inhibiting the growth and spread of tumor cells. Hydrochloric acid irinotecan is mainly used for the treatment of patients with advanced or metastatic non-small cell lung cancer with positive EGFR gene mutation. After determining the gene mutation status of the patient, the doctor can decide whether to use hydrochloric acid irinotecan as a treatment plan, and the production process of hydrochloric acid irinotecan needs to use a reaction kettle.

[0003] The existing reaction kettle usually has a simple stirring structure, which is not easy to stir the raw materials at the bottom and edge of the reaction kettle, thereby easily affecting the reaction efficiency and quality, and at the same time, it is not easy to transport the raw materials at the bottom of the reaction kettle to the upper part of the reaction kettle, and the stirring is not uniform, therefore, a reaction kettle for hydrochloric acid irinotecan is needed to solve the above problems. SUMMARY

[0004] The utility model aims at solving the problems of the prior art that the reaction kettle usually has a simple stirring structure, which is not easy to stir the raw materials at the bottom and edge of the reaction kettle, thereby easily affecting the reaction efficiency and quality, and puts forward a reaction kettle for hydrochloric acid irinotecan.

[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a reaction kettle for hydrochloric acid irinotecan, including the reaction kettle body, the top of reaction kettle body is equipped with the top cover, the inside of reaction kettle body is equipped with the rotating rod, the surface of rotating rod is equipped with and fixedly connected with the spiral blade, the surface of rotating rod and close to the top symmetry fixedly connected with the arc plate, the inner arc wall of arc plate is fixedly connected with the inclined plate, the bottom of rotating rod is fixedly connected with the support disc, the outer arc surface of top cover is fixedly connected with U type spare at equal intervals, the surface of reaction kettle body and located below U type spare is fixedly connected with buckle spare, the inside of buckle spare is embedded with screw rod, the inside of U type spare is connected with pin shaft spare through pin shaft, the bottom of pin shaft spare is fixedly connected with the top of screw rod, the surface of screw rod is equipped with and is fixedly connected with rotating piece, the surface of rotating piece is fixedly connected with the lug at equal intervals, the bottom of screw rod is fixedly connected with U type board, the inside of U type board is fixedly connected with fixed rod.

[0006] Preferably, the bottom of the reaction kettle body is fixedly connected with support legs at equal intervals near the edge, and the bottom of the support leg is trapezoidal.

[0007] Preferably, the inside of the reaction kettle body is fixedly connected with an L-shaped ring plate near the top, the inside of the L-shaped ring plate is fixedly connected with a sealing ring pad, and the inside of the L-shaped ring plate and above the sealing ring pad is provided with a ring-shaped plate, and the top of the ring-shaped plate is fixedly connected with the bottom of the top cover.

[0008] Preferably, the top of the rotating rod penetrates the center of the top cover and is rotationally connected with a bearing thereof, the surface of the top cover and near the center is fixedly connected with a driving motor, and the output end of the driving motor is fixedly connected with the top of the rotating rod.

[0009] Preferably, the outer arc wall of the arc plate is attached to the inner wall of the reaction kettle body.

[0010] Preferably, the top of the top cover is fixedly and communicatively provided with a feeding pipe, and the surface of the reaction kettle body and near the bottom is fixedly and communicatively provided with a discharging pipe.

[0011] Compared with the prior art, the utility model has the advantages and positive effects that,

[0012] 1、in the utility model, through driving motor drives rotating rod rotation, rotating rod rotation drives arc plate and inclined plate rotation, can play the effect that the raw materials of reaction kettle body edge are transported to the center, and rotating rod rotation also drives helical blade rotation, can play the effect that the raw materials of bottom and center are transported upward, so as to can reach the effect of improving mixing efficiency and uniformity.

[0013] 2、in the utility model, through embedding screw rod inside U-shaped piece, when embedding and extruding U-shaped piece bottom through rotating rotating piece, can play the effect of installing and fixing top cover, when extruding sealing ring pad inside L-shaped ring plate through ring-shaped plate, can play the effect of improving the sealing property of the reaction kettle body, and after opening cover plate, can place support disc to ground, and then can conveniently clean the mixing structure. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 a whole structure perspective view of a reaction kettle for irinotecan hydrochloride is provided for the utility model;

[0015] Figure 2 a whole structure sectional view of a reaction kettle for irinotecan hydrochloride is provided for the utility model;

[0016] Figure 3 a whole structure perspective view of a reaction kettle for irinotecan hydrochloride is provided for the utility model; Figure 2 a structure perspective view of area A in the middle;

[0017] Figure 4This invention provides a partial three-dimensional structural view of a reaction vessel for irinotecan hydrochloride.

[0018] Legend: 1. Reactor body; 2. Support leg; 3. Top cover; 4. L-shaped ring plate; 5. Ring plate; 6. Sealing ring gasket; 7. Rotating rod; 8. Spiral blade; 9. Support plate; 10. Arc plate; 11. Inclined plate; 12. Drive motor; 13. U-shaped component; 14. Pin shaft component; 15. Buckle component; 16. Screw; 17. Rotating component; 18. Protrusion; 19. U-shaped plate; 20. Fixing rod; 21. Feed pipe; 22. Discharge pipe. Detailed Implementation

[0019] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0020] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0021] Example 1, such as Figures 1-4 As shown, this utility model provides a reaction vessel for irinotecan hydrochloride, including a reaction vessel body 1, a top cover 3 on the top of the reaction vessel body 1, a rotating rod 7 inside the reaction vessel body 1, a spiral blade 8 sleeved and fixedly connected to the surface of the rotating rod 7, an arc plate 10 symmetrically fixedly connected to the surface of the rotating rod 7 near the top, inclined plates 11 fixedly connected to the inner arc walls of the arc plate 10, a support plate 9 fixedly connected to the bottom of the rotating rod 7, and U-shaped parts 13 fixedly connected at equal intervals to the outer arc surface of the top cover 3. The surface of the reactor body 1 and below the U-shaped part 13 are fixedly connected with fasteners 15. A screw 16 is embedded inside the fastener 15. A pin 14 is connected inside the U-shaped part 13. The bottom of the pin 14 is fixedly connected to the top of the screw 16. A rotating part 17 is sleeved and threaded on the surface of the screw 16. Protrusions 18 are fixedly connected at equal intervals on the surface of the rotating part 17. A U-shaped plate 19 is fixedly connected to the bottom of the screw 16. A fixing rod 20 is fixedly connected inside the U-shaped plate 19.

[0022] The effect achieved by the whole embodiment 1 is that the top of the reaction kettle body 1 is provided with a top cover 3, the inside of the reaction kettle body 1 is provided with a rotating rod 7, the surface of the rotating rod 7 is sleeved and fixedly connected with a spiral blade 8, the surface of the rotating rod 7 and close to the top is fixedly connected with an arc plate 10, the inner arc wall of the arc plate 10 is fixedly connected with an inclined plate 11, which can rotate the rotating rod 7 to drive the arc plate 10 to rotate, and the arc plate 10 drives the inclined plate 11 to rotate. The bottom of the rotating rod 7 is fixedly connected with a supporting disc 9, which can support the stirring structure. The outer arc surface of the top cover 3 is fixedly connected with a U-shaped piece 13 at equal intervals, the surface of the reaction kettle body 1 and below the U-shaped piece 13 is fixedly connected with a buckle piece 15, the inside of the buckle piece 15 is embedded with a screw rod 16, the inside of the U-shaped piece 13 is pin-connected with a pin shaft piece 14, the bottom of the pin shaft piece 14 is fixedly connected with the top of the screw rod 16, the surface of the screw rod 16 is sleeved and threadedly connected with a rotating piece 17, the surface of the rotating piece 17 is fixedly connected with a protruding block 18 at equal intervals, the bottom of the screw rod 16 is fixedly connected with a U-shaped plate 19, and the inside of the U-shaped plate 19 is fixedly connected with a fixed rod 20, which can embed the screw rod 16 into the inside of the buckle piece 15. At this time, rotating the rotating piece 17 makes the top thereof embedded into the bottom of the U-shaped piece 13, and the top cover 3 can be fixedly installed.

[0023] As shown in embodiment 2, Figures 1-4 The bottom of the reaction kettle body 1 and close to the edge is fixedly connected with a supporting leg 2 at equal intervals, and the bottom of the supporting leg 2 is trapezoidal; the inside of the reaction kettle body 1 and close to the top is fixedly connected with an L-shaped ring plate 4, the inside of the L-shaped ring plate 4 is fixedly connected with a sealing ring pad 6, and the inside of the L-shaped ring plate 4 and above the sealing ring pad 6 is provided with a ring-shaped plate 5, and the top of the ring-shaped plate 5 is fixedly connected with the bottom of the top cover 3; the top of the rotating rod 7 penetrates through the center of the top cover 3 and is rotatably connected with the bearing thereof, the surface of the top cover 3 and close to the center is fixedly connected with a driving motor 12, and the output end of the driving motor 12 is fixedly connected with the top of the rotating rod 7; the outer arc wall of the arc plate 10 is attached to the inner wall of the reaction kettle body 1; the top of the top cover 3 is fixedly and communicatively provided with a feeding pipe 21, and the surface of the reaction kettle body 1 and close to the bottom is fixedly and communicatively provided with a discharging pipe 22.

[0024] The whole embodiment 2 achieves the effect that the support legs 2 are fixedly connected at the bottom of the reaction kettle body 1 and are equidistantly arranged near the edge, the bottom of the support legs 2 is trapezoidal, and the support legs 2 can support the bottom of the reaction kettle body 1; the L-shaped ring plate 4 is fixedly connected in the inside of the reaction kettle body 1 and is close to the top, the sealing ring pad 6 is fixedly connected in the inside of the L-shaped ring plate 4, the ring plate 5 is arranged in the inside of the L-shaped ring plate 4 and is above the sealing ring pad 6, and the top of the ring plate 5 is fixedly connected with the bottom of the top cover 3, so that the top cover 3 is more sealed; the top of the rotating rod 7 penetrates through the center of the top cover 3 and is rotatably connected with a bearing of the top cover 3, the driving motor 12 is fixedly connected to the surface of the top cover 3 and is close to the center, and the output end of the driving motor 12 is fixedly connected with the top of the rotating rod 7, so that the driving motor 12 drives the rotating rod 7 to rotate; the outer arc wall of the arc plate 10 is attached to the inner wall of the reaction kettle body 1, so that the adhered raw materials on the inner wall of the reaction kettle body 1 are scraped off; the top of the top cover 3 is fixedly connected with the feeding pipe 21, and the surface of the reaction kettle body 1 is fixedly connected with the discharging pipe 22 and is close to the bottom, so that the feeding and discharging are facilitated.

[0025] Working principle: when the top cover 3 covers the top of the reaction kettle body 1, the screw rod 16 is embedded in the inside of the U-shaped piece 13, the rotating piece 17 is embedded in and extrudes the bottom of the U-shaped piece 13 by rotating, the top cover 3 is installed and fixed, the raw materials are poured into the inside of the reaction kettle body 1 through the feeding pipe 21, the rotating rod 7 is driven to rotate by the driving motor 12, the arc plate 10 and the inclined plate 11 are driven to rotate by the rotating rod 7, the raw materials at the edge of the reaction kettle body 1 are transported to the center, the screw blade 8 is driven to rotate by the rotating rod 7, and the raw materials at the bottom and the center are upwardly transported, so that the stirring efficiency and uniformity are improved.

[0026] The wiring diagram of the reaction kettle body 1 and the driving motor 12 in the utility model belongs to the common knowledge in the field, the working principle is a known technology, and the type is selected according to actual use, so the control mode and wiring arrangement of the reaction kettle body 1 and the driving motor 12 are not explained in detail.

[0027] The above is only a preferred embodiment of the utility model, and does not limit other forms of the utility model, any skilled person in the art can change or modify the above disclosed technical content into equivalent embodiments applied to other fields, but any simple modification, equivalent change and modification made on the basis of the technical essence of the utility model to the above embodiment still belongs to the protection scope of the technical scheme of the utility model.

Claims

1. A reactor for irinotecan hydrochloride comprising a reactor body (1) characterised in that: The top of the reaction kettle body (1) is provided with a top cover (3), the inside of the reaction kettle body (1) is provided with a rotating rod (7), the surface of the rotating rod (7) is sleeved and fixedly connected with a spiral blade (8), the surface of the rotating rod (7) and close to the top is fixedly connected with an arc plate (10), the inner arc wall of the arc plate (10) is fixedly connected with an inclined plate (11), the bottom of the rotating rod (7) is fixedly connected with a supporting disc (9), the outer arc surface of the top cover (3) is fixedly connected with a U-shaped piece (13) at equal intervals, the surface of the reaction kettle body (1) and below the U-shaped piece (13) is fixedly connected with a buckle piece (15), the inside of the buckle piece (15) is embedded with a screw rod (16), the inside of the U-shaped piece (13) is pin-connected with a pin shaft piece (14), the bottom of the pin shaft piece (14) is fixedly connected with the top of the screw rod (16), the surface of the screw rod (16) is sleeved and threadedly connected with a rotating piece (17), the surface of the rotating piece (17) is fixedly connected with a protruding block (18) at equal intervals, the bottom of the screw rod (16) is fixedly connected with a U-shaped plate (19), the inside of the U-shaped plate (19) is fixedly connected with a fixed rod (20).

2. A reaction vessel for irinotecan hydrochloride according to claim 1, characterized in that: The bottom of the reaction kettle body (1) and close to the edge is fixedly connected with a supporting leg (2), the bottom of the supporting leg (2) is trapezoidal.

3. A reaction vessel for irinotecan hydrochloride according to claim 1, characterized in that: The inside of the reaction kettle body (1) and close to the top is fixedly connected with an L-shaped ring plate (4), the inside of the L-shaped ring plate (4) is fixedly connected with a sealing ring pad (6), the inside of the L-shaped ring plate (4) and above the sealing ring pad (6) is provided with a ring plate (5), the top of the ring plate (5) is fixedly connected with the bottom of the top cover (3).

4. The reaction vessel for irinotecan hydrochloride according to claim 1, wherein: The top of the rotating rod (7) penetrates the center of the top cover (3) and is bearing-connected therewith, the surface of the top cover (3) and close to the center is fixedly connected with a driving motor (12), the output end of the driving motor (12) is fixedly connected with the top of the rotating rod (7).

5. The reaction vessel of irinotecan hydrochloride according to claim 1, characterized in that: The outer arc wall of the arc plate (10) is attached to the inner wall of the reaction kettle body (1).

6. The reaction vessel for irinotecan hydrochloride according to claim 1, wherein: The top of the top cover (3) is fixedly and communicatively provided with a feeding pipe (21), the surface of the reaction kettle body (1) and close to the bottom is fixedly and communicatively provided with a discharging pipe (22).

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