Biological enzyme catalysis chemical reaction tank

Abstract

The utility model discloses a biological enzyme catalysis chemical reaction tank, and relates to the field of medical intermediates. A biological enzyme catalysis chemical reaction tank comprises a tank body, and further comprises a rotating shaft rotationally connected into the tank body, a first rotating shaft, a second rotating shaft, a second rotating shaft and a third rotating shaft, the multiple groups of disturbance rods are fixedly connected to the rotating shaft at equal intervals; the decomposition tank is fixedly connected to the tank body, and a liquid conveying cavity, a decomposition cavity and a liquid spraying opening are formed in the decomposition tank; raw materials in the tank are stirred through the rotating disturbance rod, the raw materials are promoted to be evenly mixed, reactants can make more sufficient contact, meanwhile, the solid-liquid mixed raw materials in the tank are pumped into the decomposition tank through the liquid pumping component, pressure difference is formed through the diameter difference of the liquid conveying cavity and the liquid spraying opening, the raw materials are sprayed out at a high speed, and the decomposition efficiency is improved. And the raw materials which are not fully reacted and dissolved are washed by the high-speed raw material flow, so that the raw materials are further dissolved, the waste of the raw materials is reduced, and the reaction conversion rate is improved.

Description

Technical Field

[0001] This utility model belongs to the technical field of catalytic reaction vessels in pharmaceutical intermediates, specifically, it relates to a bio-enzyme catalytic chemical reaction vessel. Background Technology

[0002] In the process of bio-enzyme catalyzing chemical reactions, the mixing effect of reactants and the effective utilization of raw materials play a decisive role in the final outcome of the reaction.

[0003] In bio-enzyme catalyzed chemical reactions, in order for the reaction to proceed fully, the various reactants need to be distributed as evenly as possible in the reaction system so that the bio-enzyme can fully contact the substrate and exert its catalytic effect. Good mixing can ensure that the reaction conditions are consistent throughout the reaction system, accelerate the reaction rate, improve the reaction efficiency, and thus obtain more high-quality products.

[0004] However, existing bio-enzyme catalytic chemical reaction vessels have shortcomings in raw material mixing and unreacted material treatment. In terms of mixing methods, many reaction vessels use relatively simple stirring devices, such as only equipped with a single-shaft single-blade stirrer, which makes it difficult to mix the raw materials in the vessel evenly. This results in some areas of the vessel having excessively high reactant concentrations while others have excessively low concentrations, and the reactants cannot make sufficient contact with each other. The catalytic activity of the bio-enzyme cannot be fully utilized, which in turn affects the overall efficiency of the reaction. In view of this, this utility model is proposed. Utility Model Content

[0005] The technical problem to be solved by this utility model is to overcome the shortcomings of the prior art and provide a bio-enzyme catalytic chemical reaction vessel that can overcome or at least partially solve the above problems.

[0006] To solve the above-mentioned technical problems, the basic concept of the technical solution adopted by this utility model is as follows:

[0007] A bio-enzyme catalytic chemical reaction vessel includes a vessel body with a feeding port at the top, and further includes: a rotating shaft rotatably connected to the vessel body; multiple sets of disturbance rods fixedly connected at equal intervals to the rotating shaft; a decomposition tank fixedly connected to the vessel body, wherein the decomposition tank is provided with a delivery chamber, a decomposition chamber, and a spray nozzle, the delivery chamber being connected to the decomposition chamber through the spray nozzle, the diameter of the spray nozzle being smaller than the diameter of the delivery chamber; an ultrafine filter screen fixedly installed in the decomposition chamber, wherein the decomposition chamber is connected to the inner wall near the upper end of the vessel body through a return pipe, and a suction chamber is provided at the axis of the rotating shaft; and a liquid extraction component disposed on the vessel body and used to extract the solid-liquid mixture raw material in the vessel body through the suction chamber and transport it into the delivery chamber.

[0008] Preferably, the liquid extraction component includes a liquid extraction pump, which is fixedly installed on the tank body; it also includes an infusion pipe, one end of which is connected to the liquid suction chamber through a rotary joint, and the other end is fixedly connected to the input end of the liquid extraction pump, and the output end of the liquid extraction pump is fixedly connected to the infusion chamber through an inlet pipe.

[0009] In order to ensure that the refluxed material is evenly dispersed in the raw materials in the tank, avoiding the problem of excessively high or low local concentrations, and further improving the mixing uniformity of the raw materials, preferably, a hollow cavity is formed between the inner and outer walls near the upper end of the tank. The hollow cavity is arranged in a ring shape. Multiple spray holes connected to the hollow cavity are equidistantly formed on the inner wall of the tank. The end of the reflux pipe away from the decomposition chamber is connected to the hollow cavity.

[0010] In order to drive the rotating shaft to rotate the disturbance rod and mix the raw materials in the tank, preferably, a motor is fixedly installed on the tank, a gear one is fixedly connected to the output end of the motor, and a gear two is fixedly installed at one end of the rotating shaft that passes through the tank, and the gear one and gear two are meshed together.

[0011] To facilitate the discharge of the products after the reaction is completed, preferably, the bottom of the tank is fixedly connected to a discharge pipe, and a valve switch is provided on the discharge pipe.

[0012] To reduce product residue in the can, the bottom inner wall of the can is further designed to be conical.

[0013] By adopting the above technical solution, this utility model has the following beneficial effects compared with the prior art:

[0014] This invention uses a motor to drive a rotating shaft to rotate, which in turn drives a stirring rod to stir the raw materials in the tank, promoting uniform mixing of the raw materials and enabling the reactants to come into more thorough contact.

[0015] The pumping unit draws the solid-liquid mixture from the tank into the decomposition tank. The pressure difference between the diameter of the delivery chamber and the spray nozzle is used to make the raw material spray out at high speed. Then, it is filtered through an ultra-fine filter. The high-speed raw material flow washes away the raw material that has not been fully reacted and dissolved, promoting its further dissolution, reducing raw material waste and improving the reaction conversion rate.

[0016] After processing, the material enters the hollow cavity at the upper end of the tank through the reflux pipe, and is then evenly sprayed onto the raw materials inside the tank through the spray nozzles, achieving secondary mixing. This improves the completeness of the reaction, increases the amount of product generated, enhances the stability of the reaction, reduces reaction rate fluctuations, further promotes the full utilization of raw materials, and improves the conversion rate of raw materials. Attached Figure Description

[0017] Figure 1 This is a cross-sectional view of the tank body and decomposition tank of this utility model;

[0018] Figure 2 This is a schematic diagram of the structure of this utility model;

[0019] Figure 3 This is a cross-sectional view of the decomposition tank and ultrafine filter screen of this utility model;

[0020] Figure 4 This is a utility model Figure 1 Enlarged view of section A;

[0021] Figure 5 This is a utility model Figure 1 Enlarged view of section B.

[0022] In the diagram: 1. Tank body; 101. Feed port; 102. Discharge pipe; 2. Rotating shaft; 201. Disturbing rod; 3. Motor; 301. Gear 1; 302. Gear 2; 4. Decomposition tank; 401. Infusion chamber; 402. Decomposition chamber; 403. Spray nozzle; 404. Ultrafine filter; 405. Inlet pipe; 406. Return pipe; 407. Hollow cavity; 408. Spray hole; 5. Pump; 501. Infusion pipe; 502. Rotary joint; 503. Suction chamber. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions in the embodiments will be clearly and completely described below with reference to the accompanying drawings. The following embodiments are used to illustrate this utility model, but are not intended to limit the scope of this utility model.

[0024] Example 1:

[0025] Reference Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 A bio-enzyme catalytic chemical reaction vessel includes a vessel body 1 with a feeding port 101 at the top. It also includes: a rotating shaft 2 rotatably connected within the vessel body 1; multiple sets of disturbance rods 201 equidistantly fixedly connected to the rotating shaft 2; a decomposition tank 4 fixedly connected to the vessel body 1, wherein the decomposition tank 4 is provided with a delivery chamber 401, a decomposition chamber 402, and a spray nozzle 403. The delivery chamber 401 is connected to the decomposition chamber 402 via the spray nozzle 403, and the diameter of the spray nozzle 403 is smaller than the diameter of the delivery chamber 401; an ultrafine filter 404 fixedly installed in the decomposition chamber 402, wherein the decomposition chamber 402 is connected to the inner wall near the upper end of the vessel body 1 via a return pipe 406; a suction chamber 503 is provided at the axis of the rotating shaft 2; and a liquid extraction component, disposed on the vessel body 1, used to extract the solid-liquid mixture from the vessel body 1 through the suction chamber 503 and transport it into the delivery chamber 401.

[0026] The liquid extraction component includes a liquid extraction pump 5, which is fixedly installed on the tank body 1; it also includes an infusion pipe 501, one end of which is connected to the liquid suction chamber 503 through a rotary joint 502, and the other end is fixedly connected to the input end of the liquid extraction pump 5. The output end of the liquid extraction pump 5 is fixedly connected to the infusion chamber 401 through an inlet pipe 405.

[0027] A hollow cavity 407 is provided between the inner and outer walls near the upper end of the tank body 1. The hollow cavity 407 is arranged in a ring shape. Multiple spray holes 408 connected to the hollow cavity 407 are provided at equal intervals on the inner wall of the tank body 1. The end of the return pipe 406 away from the decomposition chamber 402 is connected to the hollow cavity 407.

[0028] A motor 3 is fixedly installed on the tank body 1. A gear 301 is fixedly connected to the output end of the motor 3. A gear 302 is fixedly installed at one end of the rotating shaft 2 that passes through the tank body 1. The gear 301 and the gear 302 are meshed and connected.

[0029] In use, firstly, solid and liquid raw materials are added sequentially into tank 1 through feeding port 101. Then, motor 3 is started. Motor 3 drives rotating shaft 2 to rotate through meshing gear 1 301 and gear 2 302. The rotating shaft 2 drives multiple sets of disturbance rods 201 to stir the raw materials in the tank, promoting uniform mixing. At the same time, liquid pump 5 is started, extracting the solid-liquid mixture from the tank through delivery pipe 501, rotary joint 502, and suction chamber 503 at the axis of rotating shaft 2. After being pressurized by liquid pump 5, it is transported to delivery chamber 401 of decomposition tank 4 through inlet pipe 405. At this time, the raw materials in delivery chamber 401 are sprayed out at high speed into decomposition chamber 402 because the diameter of spray nozzle 403 is smaller than that of delivery chamber 401. The raw materials are filtered through ultrafine filter screen 404 in decomposition chamber 402, allowing them to pass through the spray nozzle 403. The filter can intercept unreacted and dissolved raw materials, and the high-speed raw material flow sprayed from the spray nozzle 403 washes the unreacted and dissolved raw materials intercepted on the ultrafine filter screen 404, promoting further dissolution. This not only improves the reaction conversion rate and reduces raw material waste, but also enhances the uniformity of the reaction and optimizes the product quality. Then, the treated material enters the hollow cavity 407 at the upper end of the tank 1 through the return pipe 406. Since the hollow cavity 407 is arranged in a ring shape, it is connected to multiple spray holes 408 equidistantly opened on the inner wall of the tank 1, so that the returned material is evenly sprayed onto the raw materials in the tank through the spray holes 408, thereby achieving secondary mixing, improving the sufficiency of the reaction, allowing the reactants to contact and react more fully, increasing the product generation, enhancing the stability of the reaction, reducing reaction rate fluctuations, further promoting the full utilization of raw materials, and improving the raw material conversion rate.

[0030] Example 2:

[0031] Reference Figure 1 , Figure 2 A bio-enzyme catalytic chemical reaction vessel is basically the same as in Example 1. Furthermore, the bottom of the vessel 1 is fixedly connected to a discharge pipe 102, and a valve switch is provided on the discharge pipe 102. When the reaction is completed, by opening the valve switch on the discharge pipe 102, the product can be discharged from the vessel 1 under the action of gravity, thereby facilitating the discharge of the product after the reaction is completed.

[0032] Example 3:

[0033] Reference Figure 1 A bio-enzyme catalytic chemical reaction vessel, which is basically the same as in Example 1, but further, the bottom inner wall of the vessel 1 is set in a conical shape;

[0034] Because the bottom inner wall of tank 1 is conical, the product will gather along the conical wall towards the discharge pipe 102 under the action of gravity during discharge, which not only improves the efficiency of product discharge, but also reduces the product residue in the tank.

[0035] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model in any way. Although the present utility model has been disclosed above with reference to a preferred embodiment, it is not intended to limit the present utility model.

Claims

1. A biological enzyme catalytic chemical reaction tank, comprising a tank body (1), a feeding opening (101) is arranged at the top of the tank body (1), characterized in that, Also include: Rotary shaft (2) rotationally connected in the tank body (1); Multiple sets of disturbance rods (201) are fixedly connected on the rotary shaft (2) at equal intervals; Decomposition tank (4) is fixedly connected on the tank body (1), Wherein, the decomposition tank (4) is provided with infusion cavity (401), decomposition cavity (402), liquid injection port (403), the infusion cavity (401) is communicated with the decomposition cavity (402) through the liquid injection port (403), the diameter of the liquid injection port (403) is less than the diameter of the infusion cavity (401); Ultrafine filter screen (404) is fixedly installed in the decomposition cavity (402), Wherein, the decomposition cavity (402) is communicated with the inner wall near the upper end of the tank body (1) through the reflux pipe (406), the shaft center of the rotary shaft (2) is provided with a liquid suction cavity (503); The liquid pumping component is arranged on the tank body (1) and used for pumping the preliminarily mixed solid-liquid mixture in the tank body (1) through the liquid suction cavity (503) and conveying into the infusion cavity (401).

2. The biocatalytic chemical reaction tank according to claim 1, characterized in that, The liquid pumping component includes a liquid pumping pump (5) fixedly installed on the tank body (1); It also includes an infusion tube (501), one end of the infusion tube (501) is communicated with the liquid suction cavity (503) through a rotary joint (502), the other end is fixedly communicated with the input end of the liquid pumping pump (5), the output end of the liquid pumping pump (5) is fixedly communicated with the infusion cavity (401) through a liquid inlet pipe (405).

3. The biocatalytic chemical reaction tank according to claim 1, characterized in that, A hollow cavity (407) is arranged between the inner and outer walls near the upper end of the tank body (1), the hollow cavity (407) is arranged in a ring shape, a plurality of liquid injection holes (408) are arranged on the inner wall of the tank body (1) at equal intervals and communicated with the hollow cavity (407), and the end of the reflux pipe (406) away from the decomposition cavity (402) is communicated with the hollow cavity (407).

4. The biocatalytic chemical reaction tank according to claim 1, characterized in that, The motor (3) is fixedly installed on the tank body (1), the output end of the motor (3) is fixedly connected with gear one (301), one end of the rotary shaft (2) penetrating the tank body (1) is fixedly installed with gear two (302), and the gear one (301) is engaged with the gear two (302).

5. The biocatalytic chemical reaction tank according to claim 1, characterized in that, The bottom of the tank body (1) is fixedly communicated with a discharge pipe (102), and the discharge pipe (102) is provided with a valve switch.

6. The bio-enzyme catalyzed chemical reaction tank according to claim 5, characterized in that, The inner wall of the bottom of the tank body (1) is conical.

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