Eluting device for washing liquor of coating-free tube

Abstract

The utility model relates to the technical field of diagnostic reagents, in particular to an elution device for placing a coating-free tube washing liquid, which comprises a base and a lead glass cover, a coating tube support is movably arranged on the base, and a push-pull component penetrating through the lead glass cover is arranged on one side of the coating tube support. A coating pipe support is arranged on the base, a plurality of coating pipes are arranged on the coating pipe support, a plurality of through holes are formed in the top of the lead glass cover, a washing liquid storage tank is arranged on one side of the base, and the washing liquid storage tank conveys washing liquid into the coating pipes through a conveying pump and a washing liquid conveying pipe; a washing liquid suction device is arranged on the other side of the base and communicated with a buffer tank through an exhaust pipe, the buffer tank is communicated with a waste washing liquid storage tank through a connecting pipe, and the waste washing liquid storage tank sucks out washing liquid in the coating pipe through a washing liquid suction pipe. The elution device is reasonable in design, the washing liquid in the coating pipe can be conveniently added and sucked, the operation is simple and convenient, the labor intensity of workers is reduced, and the safety risk is also reduced.

Description

Technical Field

[0001] This utility model relates to the field of diagnostic reagent technology, and in particular to an elution device for washing solution of radioimmunoassay coated tubes. Background Technology

[0002] Radioimmunoassay (RIA) is a technique for immunological detection using radiolabeled antigens or antibodies, and it is divided into liquid-phase and solid-phase methods. The radioimmunoassay tube coating method is one application of RIA. Its basic principle is to immobilize antibodies on the surface of a solid-phase immunoadsorption carrier (usually a plastic tube or microplate), and then add the sample to be tested and the labeled antigen or antibody. Through competitive binding, unlabeled antigens or antibodies bind to the antibodies immobilized on the tube surface, while labeled antigens or antibodies bind to the remaining antibodies. By measuring the signal from the radionuclide, the content of antigens or antibodies in the sample can be calculated. However, the following problems exist in actual operation: After the sample and labeled antigen are added to the coated tube coated with antibody, and after incubation and reaction, the operator adds washing solution from a wash bottle to the inside of the coated tube for washing, and then uses a syringe to aspirate the washing solution, repeating this process twice. This operating method, on the one hand, increases the labor intensity for workers, and a slight oversight could lead to the wrong addition of washing solution or spillage of the extracted solution; on the other hand, the samples contain radioactive elements, and prolonged exposure to these elements could pose safety risks to workers. Therefore, to address these issues, it is necessary to develop a radioactive, non-coated tube washing solution elution device. Utility Model Content

[0003] The technical problem to be solved by this utility model is to provide a washing and elution device for tube washing liquid that is free from the shortcomings of the prior art. This washing and elution device facilitates the addition and discharge of washing liquid, greatly improves work efficiency, and reduces labor intensity and safety risks.

[0004] To solve the above-mentioned technical problems, the technical solution of this utility model is as follows:

[0005] A washing device for removing washing solution from coated tubes includes a base and a lead glass cover. A coated tube support is movably mounted on the base, and a push-pull component passing through the lead glass cover is provided on one side of the coated tube support. Multiple coated tubes are mounted on the coated tube support, and multiple through holes are provided on the top of the lead glass cover. A washing solution storage tank is provided on one side of the base, and the washing solution storage tank delivers the washing solution to the interior of the coated tubes through a delivery pump and a washing solution delivery pipe. A washing solution suction device is provided on the other side of the base, and the washing solution suction device is connected to a buffer tank through a suction pipe. The buffer tank is connected to a waste washing solution storage tank through a connecting pipe, and the waste washing solution storage tank sucks out the washing solution from the interior of the coated tubes through a washing solution suction pipe.

[0006] As an improved technical solution, the coated tube support is slidably connected to the base, the base is provided with a sliding groove, and the bottom of the coated tube support is provided with a slider that matches the sliding groove.

[0007] As an improved technical solution, the push-pull component is a push-pull rod, which includes two crossbars and a connecting rod disposed between the two crossbars. A through hole is provided on one side of the lead glass cover, and the two crossbars pass through the through hole and are detachably connected to the cover tube support.

[0008] As an improved technical solution, the washing liquid delivery pipe is equipped with a flow meter and a solenoid valve, and the flow meter, solenoid valve and delivery pump are electrically connected to the controller.

[0009] As an improved technical solution, the end of the washing liquid delivery pipe is provided with a tapered section.

[0010] As an improved technical solution, the washing liquid aspiration device is an electric suction device.

[0011] As an improved technical solution, lead plate protective covers are respectively provided on the outer wall of the waste washing liquid storage tank and the outer wall of the buffer tank.

[0012] As an improved technical solution, one end of the washing liquid suction tube is connected to the waste washing liquid storage tank, and the other end of the washing liquid suction tube is provided with a washing liquid suction head.

[0013] After adopting the above technical solution, the beneficial effects of this utility model are:

[0014] The washing device for removing the coating tube washing solution includes a base and a lead glass cover. A coating tube support is movably mounted on the base, and a push-pull component passing through the lead glass cover is provided on one side of the coating tube support. Multiple coating tubes are mounted on the coating tube support, and multiple through holes are provided on the top of the lead glass cover. A washing solution storage tank is provided on one side of the base, and the washing solution storage tank delivers the washing solution to the inside of the coating tube through a transfer pump and a washing solution transfer pipe. A washing solution suction device is provided on the other side of the base, and the washing solution suction device is connected to a buffer tank through a suction pipe. The buffer tank is connected to a waste washing solution storage tank through a connecting pipe, and the waste washing solution storage tank sucks out the washing solution inside the coating tube through a washing solution suction pipe. The experimenters placed the reacted coated tube onto a coated tube support, covered it with a lead glass cover, and used a push-pull mechanism to push the support closer to the washing solution storage tank. The outlet end of the washing solution delivery pipe was aligned with the coated tube, and the controller started the delivery pump. The washing solution inside the storage tank flowed into the coated tube via the pump. Then, using the push-pull mechanism, the support was pulled towards the washing solution suction device. The suction pipe was aligned with the coated tube, and the suction device activated. The washing solution inside the coated tube flowed into the waste washing solution storage tank via the suction pipe. A buffer tank prevented waste washing solution from entering the suction device. This elution device is rationally designed, facilitates the addition and removal of washing solution from the coated tube, is simple and convenient to operate, reduces the labor intensity of workers, and also lowers safety risks.

[0015] Because the coated tube support is slidably connected to the base, and the base has a groove, while the bottom of the coated tube support has a slider that matches the groove, this design facilitates the left and right sliding of the coated tube support along the base.

[0016] The push-pull component is a push-pull rod, which includes two crossbars and a connecting rod between them. One side of the lead glass cover has a through hole through which the two crossbars pass and are detachably connected to the coated tube support. The experimenter can move the coated tube support by holding the connecting rod and moving it to one side or by pushing it. The detachable connection between the push-pull rod and the coated tube support facilitates disassembly and installation; the through hole design allows the push-pull rod to apply a pushing or pulling force to the coated tube support, thus enabling its movement.

[0017] The washing solution delivery pipe is equipped with a flow meter and a solenoid valve, which are electrically connected to the controller. When washing solution needs to be added, the controller starts the delivery pump and flow meter, and the washing solution enters the interior of the coated tube along the washing solution delivery pipe. This design facilitates the addition of washing solution and also makes it easy to control the amount of washing solution added.

[0018] The washing solution delivery pipe has a tapered end. This tapered design prevents spillage when the washing solution is added.

[0019] Because the washing solution suction device is an electric suction device, the negative pressure generated by the electric suction device facilitates the suction of the washing solution from the coated tube.

[0020] Lead plates are installed on the outer walls of both the waste washing liquid storage tank and the buffer tank. These lead plates effectively prevent radiation exposure to workers.

[0021] One end of the washing liquid suction pipe is connected to the waste washing liquid storage tank, and the other end is equipped with a washing liquid suction head. Under the action of the washing liquid suction device, the washing liquid inside the coated pipe flows along the washing liquid suction head and the washing liquid suction pipe into the interior of the waste washing liquid storage tank. The washing liquid suction head is designed to facilitate the suction of the washing liquid. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of a detection device for the opening stability of a diagnostic reagent according to the present invention;

[0023] Among them, 1-base, 2-lead glass cover, 20-through hole, 3-coated tube support, 30-slider, 4-push-pull component, 40-crossbar, 41-connecting rod, 5-coated tube, 6-washing liquid storage tank, 7-transfer pump, 8-washing liquid transfer pipe, 80-conical part, 9-washing liquid suction device, 10-extraction pipe, 11-buffer tank, 12-connecting pipe, 13-waste washing liquid storage tank, 14-washing liquid suction pipe, 15-flow meter, 16-solenoid valve, 17-controller, 18-lead plate protective cover, 19-washing liquid suction head, 22-slide chute. Detailed Implementation

[0024] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0025] An elution device for dispensing washing solution for uncoated tubes, such as Figure 1 As shown, the device includes a base 1 and a lead glass cover 2. A coated tube support 3 is movably mounted on the base 1. A push-pull component 4 that passes through the lead glass cover 2 is located on one side of the coated tube support 3. Multiple coated tubes 5 (placed in the grooves of the coated tube support) are mounted on the coated tube support 3. Multiple through holes 20 are located on the top of the lead glass cover 2. A washing liquid storage tank 6 is located on one side of the base 1. The washing liquid storage tank 6 delivers the washing liquid to the inside of the coated tubes 5 through a delivery pump 7 and a washing liquid delivery pipe 8. A washing liquid suction device 9 (electric suction device, purchased from the manufacturer) is located on the other side of the base 1. The washing liquid suction device 9 is connected to a buffer tank 11 through a suction pipe 10. The buffer tank 11 is connected to a waste washing liquid storage tank 13 through a connecting pipe 12. The waste washing liquid storage tank 13 sucks out the washing liquid inside the coated tubes 5 through a washing liquid suction pipe 14.

[0026] The experimenters placed the reacted coated tube onto a coated tube support, covered it with a lead glass cover, and used a push-pull mechanism to push the support closer to the washing solution storage tank. The outlet end of the washing solution delivery pipe was aligned with the coated tube, and the controller started the delivery pump. The washing solution inside the storage tank flowed into the coated tube via the pump. Then, using the push-pull mechanism, the support was pulled towards the washing solution suction device. The suction pipe was aligned with the coated tube, and the suction device activated. The washing solution inside the coated tube flowed into the waste washing solution storage tank via the suction pipe. A buffer tank prevented waste washing solution from entering the suction device. This elution device is rationally designed, facilitates the addition and removal of washing solution from the coated tube, is simple and convenient to operate, reduces the labor intensity of workers, and also lowers safety risks.

[0027] The coated tube support 3 is slidably connected to the base 1. The base 1 is provided with a sliding groove 20, and the bottom of the coated tube support 3 is provided with a slider 30 that matches the sliding groove. When a pushing or pulling force is applied to the coated tube support, the slider at the bottom of the coated tube support moves along the sliding groove, thereby adjusting the position of the coated tube support.

[0028] The push-pull component 4 is a push-pull rod, which includes two crossbars 40 and a connecting rod 41 positioned between the two crossbars 40. A through hole 20 is provided on one side of the lead glass cover 2. The two crossbars pass through the through hole and are detachably connected to the coated tube support (one end of each crossbar is threaded to the outer wall of one side of the coated tube support, and the other end of each crossbar has a slot; the connecting rod has a locking block that matches the slot). The experimenter can move the coated tube support by holding the connecting rod and moving it to one side or pushing it. The detachable connection between the push-pull rod and the coated tube support facilitates disassembly and installation; the through hole design allows the push-pull rod to apply a pushing or pulling force to the coated tube support, thus enabling its movement.

[0029] The washing liquid delivery pipe 8 is equipped with a flow meter 15 and a solenoid valve 16. The flow meter 15, solenoid valve 16, and delivery pump 7 are electrically connected to the controller 17. When washing liquid needs to be added, the controller starts the delivery pump and flow meter, and the solenoid valve opens. The washing liquid enters the interior of the coated tube along the washing liquid delivery pipe. When the required amount of washing liquid is added, the delivery pump stops running, the solenoid valve closes, and then the outlet end of the washing liquid delivery pipe is quickly aligned with the next coated tube. The controller starts the delivery pump and flow meter again, and the solenoid valve opens, sequentially adding washing liquid into the interior of the coated tubes.

[0030] The end of the washing liquid delivery pipe 8 is provided with a tapered section 80. The tapered section is designed to prevent spillage when the washing liquid is added.

[0031] Lead plate protective covers 18 are installed on the outer walls of the waste washing liquid storage tank 13 and the buffer tank 11, respectively. By designing lead plate protective covers, the radiation of radioactive elements to the workers' bodies can be effectively prevented.

[0032] One end of the washing liquid suction pipe 14 is connected to the waste washing liquid storage tank 13, and the other end of the washing liquid suction pipe 14 is equipped with a washing liquid suction head 19. Under the action of the washing liquid suction device, the washing liquid in the coated pipe enters the interior of the waste washing liquid storage tank along the washing liquid suction head and the washing liquid suction pipe. The washing liquid suction head is designed to facilitate the suction of the washing liquid.

[0033] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A washing and elution device for removing washing solution from uncoated tubes, characterized in that, The device includes a base and a lead glass cover. A coated tube support is movably mounted on the base, and a push-pull component passing through the lead glass cover is provided on one side of the coated tube support. Multiple coated tubes are mounted on the coated tube support, and multiple through holes are provided on the top of the lead glass cover. A washing liquid storage tank is provided on one side of the base, and the washing liquid storage tank delivers washing liquid to the inside of the coated tubes through a delivery pump and a washing liquid delivery pipe. A washing liquid suction device is provided on the other side of the base, and the washing liquid suction device is connected to a buffer tank through a suction pipe. The buffer tank is connected to a waste washing liquid storage tank through a connecting pipe, and the waste washing liquid storage tank sucks out the washing liquid inside the coated tubes through a washing liquid suction pipe.

2. The elution apparatus for washing fluid in tubes without coating according to claim 1, characterized in that, The coated tube support is slidably connected to the base, the base is provided with a sliding groove, and the bottom of the coated tube support is provided with a slider that matches the sliding groove.

3. The elution apparatus for washing fluid in tubes without coating according to claim 1, characterized in that, The push-pull component is a push-pull rod, which includes two crossbars and a connecting rod disposed between the two crossbars. One side of the lead glass cover is provided with a through hole, and the two crossbars pass through the through hole and are detachably connected to the cover tube support.

4. The elution apparatus for washing fluid in tubes without coating according to claim 1, characterized in that, The washing liquid delivery pipe is equipped with a flow meter and a solenoid valve, and the flow meter, solenoid valve and delivery pump are electrically connected to the controller.

5. The elution apparatus for washing fluid in tubes without coating according to claim 1, characterized in that, The end of the washing liquid delivery pipe is provided with a tapered section.

6. The elution apparatus for washing fluid in tubes without coating according to claim 1, characterized in that, The washing liquid suction device is an electric suction device.

7. The elution apparatus for washing fluid in tubes free from coating as described in claim 1, characterized in that, Lead plate protective covers are respectively installed on the outer wall of the waste washing liquid storage tank and the outer wall of the buffer tank.

8. The elution apparatus for washing fluid in tubes free from coating according to claim 1, characterized in that, One end of the washing liquid suction tube is connected to the waste washing liquid storage tank, and the other end of the washing liquid suction tube is equipped with a washing liquid suction head.

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