Chromatographic column device

Abstract

The utility model discloses a chromatographic column device which comprises a column tube and a plunger arranged in the column tube, a flaring part is arranged on the inner wall of one end of the column tube, a first sealing element and a second sealing element are arranged on the plunger, a channel used for exhausting air and / or introducing liquid is arranged between the first sealing element and the second sealing element, and the first sealing element and the second sealing element are arranged in the channel. And the flaring part is used for forming a gap for exhausting between the second sealing piece and the column pipe. When exhaust is needed, the plunger moves in the column pipe, a gap is generated when the second sealing piece moves to the flaring part at one end of the column pipe, bubbles can enter the channel through the gap and are finally exhausted through the channel, and tests show that the exhaust effect is good; at the moment, the first sealing piece is still tightly attached to the inner wall of the column pipe to keep a sealing state, reliability is good, only a flaring part needs to be machined on the inner wall of the column pipe, the structure is simple, cost is low, meanwhile, the plunger only needs to move in the column pipe in the exhaust process, and operation is convenient.

Description

TECHNICAL FIELD

[0001] The utility model relates to separating and purifying equipment, especially a chromatographic column device. BACKGROUND

[0002] The chromatographic column is used in a production process, and bubbles can greatly affect column efficiency, so it is necessary to remove the bubbles in the column pipe as much as possible. Currently, there are two methods for removing the bubbles in the column pipe on the market: the first method is to set a concave step in the middle section of the column pipe to remove the bubbles, and the second method is to tilt the column head to remove the bubbles. The first method needs to increase the length of the column pipe, which increases the complexity of the structure and the cost, and the second method is inconvenient to operate and has a complex structure. SUMMARY

[0003] The utility model solves the technical problem of overcoming the prior art, and provides a chromatographic column device which is simple in structure, low in cost and convenient to operate.

[0004] To solve the above technical problems, the utility model adopts the following technical scheme:

[0005] A chromatographic column device comprises a column pipe and a plunger arranged in the column pipe, an inner wall of one end of the column pipe is provided with an expanded portion, the plunger is provided with a first sealing element and a second sealing element, a channel for exhausting and / or introducing liquid is arranged between the first sealing element and the second sealing element, and the expanded portion is used for forming a gap between the second sealing element and the column pipe for exhausting.

[0006] As a further improvement of the above technical scheme, the plunger is provided with an exhaust joint, and the channel is in communication with the exhaust joint.

[0007] As a further improvement of the above technical scheme, the exhaust joint is provided with a detachable plugging element.

[0008] As a further improvement of the above technical scheme, a plurality of channels are arranged, and the plurality of channels are distributed along the circumferential direction of the plunger.

[0009] As a further improvement of the above technical scheme, the expanded portion is a conical structure.

[0010] Compared with the prior art, the utility model has the advantages of:

[0011] The utility model discloses a chromatography column device, when needing exhaust, plunger moves in the column pipe inside, when second sealing piece moves to the flared portion of column pipe one end and will produce gap, bubble can enter the passageway through the gap, finally discharges through the passageway, and the exhaust effect is good through the test, when the first sealing piece is still sealed state of close adhesion with the inner wall of column pipe, and the reliability is good, and the column pipe only needs flared portion to process the inner wall, and the structure is simple, and the cost is low, and the plunger only needs to move in the column pipe inside during the exhaust process, and the operation is convenient.

[0012] Other features and advantages of the utility model will be described in detail in the following specific embodiment part. BRIEF DESCRIPTION OF DRAWINGS

[0013] Figure 1 It is the sectional structure schematic diagram of chromatography column device of the utility model.

[0014] Figure 2 It is Figure 1 The enlarged view of A in figure.

[0015] The various reference numerals in the figure represent: 1, column pipe;11, flared portion;2, plunger;21, passageway;3, first sealing piece;4, second sealing piece;5, exhaust joint;51, plugging piece. DETAILED DESCRIPTION

[0016] In the description of the utility model, it is understood that the orientation or positional relationship of the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the utility model and simplifying the description, and therefore cannot be understood as indicating or implying that the indicated device or element must have a particular orientation, a particular orientation and operation, and therefore cannot be understood as a limitation on the utility model.

[0017] In addition, the terms "first", "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined with "first", "second" can explicitly or implicitly include one or more features. In the description of the utility model, the meaning of "multiple" is two or more than two, unless otherwise specifically limited.

[0018] In the utility model, unless another definite provision and limitation, the terms "assemble", "connect", "connect", "fix" and so on should do the broad sense understanding, for example, can be fixed connection, also can be detachable connection, or be integrated;Can be mechanical connection, also can be electrical connection;Can be direct connection, also can through the intermediate medium indirectly connect, can be two element inside's intercommunication or two element's mutual action relationship.For the ordinary skilled person in the art, can understand the concrete meaning of the above terms in the utility model according to specific circumstances.

[0019] The utility model will be further explained in detail in combination with the drawings and specific embodiments of the specification.

[0020] Figures 1 to 2 An embodiment of the utility model is shown, and the chromatography column device of the embodiment includes a column tube 1 and a plunger 2 arranged inside the column tube 1, the inner wall of one end of the column tube 1 is provided with a flared portion 11, the plunger 2 is provided with a first sealing element 3 and a second sealing element 4, a channel 21 for exhausting and / or introducing liquid is arranged between the first sealing element 3 and the second sealing element 4, and the flared portion 11 is used to form a gap for exhausting between the second sealing element 4 and the column tube 1. In the embodiment, the flared portion 11 is arranged at the lower end of the column tube 1, and correspondingly, the first sealing element 3 is located above the second sealing element 4;The first sealing element 3 and the second sealing element 4 may, for example, be O-shaped sealing rings, mechanical seals, etc.

[0021] When the chromatography column device of the embodiment needs to exhaust, the plunger 2 moves downward inside the column tube 1, a gap is formed when the second sealing element 4 moves to the flared portion 11 at the lower end of the column tube 1, bubbles can enter the channel 21 through the gap, and finally be exhausted through the channel 21, and experiments show that the exhaust effect is good;At this time, the first sealing element 3 is still in close contact with the inner wall of the column tube 1 to maintain a sealed state, so that the cavity above the plunger 1 is prevented from being contaminated, the reliability is good, and the column tube 1 only needs to be processed with the flared portion 11 on the inner wall, so that the structure is simple and the cost is low;At the same time, the plunger 2 only needs to move inside the column tube 1 during the exhaust process, so that the operation is convenient. Of course, in other embodiments, the channel 21 can also be used to introduce liquid such as alcohol in addition to exhausting bubbles.

[0022] Further, in the embodiment, the plunger 2 is provided with an exhaust connector 5, and the channel 21 communicates with the exhaust connector 5. The exhaust connector 5 is arranged to facilitate the connection of the pipeline, and the gas can be exhausted to the outside of the column tube 1 through the exhaust connector 5 after passing through the channel 21.

[0023] Further, in the embodiment, the exhaust joint 5 is provided with a detachable blocking member 51 (for example, detachable connection is realized by thread connection, clamping and the like). When there is no need to exhaust bubbles or to pass liquid, the exhaust joint 5 can be blocked by the blocking member 51 (during transportation of the chromatographic column device, alcohol can be passed into the channel 21, at this time, the first sealing member 3 and the second sealing member 4 are tightly attached to the inner wall of the column tube 1, and the sealing state is maintained, the alcohol can sterilize the channel 21, and at the same time, the channel 21 is prevented from being contaminated).

[0024] As a preferred embodiment, the channel 21 is provided with a plurality of channels 21, and the plurality of channels 21 are distributed along the circumferential direction of the plunger 2, which is beneficial to exhaust bubbles at all edges of the plunger 2 and improve the exhaust bubble efficiency.

[0025] As a preferred embodiment, the flared portion 11 is a tapered structure, which is beneficial to form a gap between the inner wall of the column tube 1 and the second sealing member 4, adjust the size of the gap, and facilitate machining.

[0026] Although the utility model has been disclosed as above with preferred embodiments, it is not intended to limit the utility model. Any person skilled in the art can make many possible changes and modifications to the technical scheme of the utility model by using the disclosed technical content, or modify equivalent embodiments with equivalent changes. Therefore, any simple modification, equivalent change and modification of the above embodiments according to the technical essence of the utility model should fall within the scope of protection of the utility model technical scheme.

Claims

1. A chromatography column device comprising a column tube (1) and a plunger (2) arranged inside the column tube (1), characterized in that: The inner wall of one end of the column pipe (1) is provided with a flared portion (11), the plunger (2) is provided with a first sealing element (3) and a second sealing element (4), a passage (21) for exhausting and / or introducing liquid is arranged between the first sealing element (3) and the second sealing element (4), and the flared portion (11) is used for forming a gap between the second sealing element (4) and the column pipe (1) for exhausting.

2. The chromatography column device of claim 1, wherein: The plunger (2) is provided with an exhaust joint (5), and the passage (21) communicates with the exhaust joint (5).

3. The chromatography column device of claim 2, wherein: The exhaust joint (5) is provided with a detachable blocking element (51).

4. The chromatography column device of any one of claims 1-3, wherein: The passage (21) is provided with a plurality of passages (21), and the plurality of passages (21) are distributed along the circumferential direction of the plunger (2).

5. The chromatography column device of any one of claims 1-3, wherein: The flared portion (11) is a tapered structure.

Images