High-purity heparin sodium fine filtration mechanism

Abstract

The utility model discloses a high-purity heparin sodium fine filtration mechanism which comprises a liquid inlet filter pipe, one end of the liquid inlet filter pipe is connected with a first fine filtration tank in a sealed mode through a pipeline, one end of the first fine filtration tank is connected with a second fine filtration tank in a sealed mode through a filtration pipeline, and fine filtration assemblies are arranged in the first fine filtration tank and the second fine filtration tank. The fine filtration assembly is of a detachable structure, and a liquid discharge filter pipe is arranged at one end of the second fine filtration tank. According to the utility model, the two refined filtration tank structures are arranged, so that impurity particles in a heparin sodium solution can be deeply and finely filtered layer by layer, the refined filtration device has the advantage of good filtration effect, meanwhile, the refined filtration assembly can be conveniently taken, replaced and cleaned, and the refined filtration screen structures are arranged in the pipelines at the liquid inlet end and the liquid outlet end of the solution, so that the refined filtration effect is improved. The heparin sodium solution can be further finely filtered, impurity particles in the heparin sodium solution can be effectively removed, it is guaranteed that the heparin sodium solution is high in purity and free of impurities, and the forming quality of the heparin sodium solution is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to heparin sodium processing technical field, concretely is a high -purity heparin sodium fine filter mechanism. BACKGROUND

[0002] Heparin sodium can interfere with many links of blood coagulation process, has anticoagulation in vivo and outside, its mechanism is relatively complex, mainly through the combination with antithrombin III (AT-III), and enhances the inhibition of the latter to activated II, IX, X, XI and XII coagulation factors, its consequence involves preventing platelet aggregation and destruction, hindering the formation of coagulation activator, preventing prothrombin from becoming thrombin, inhibiting thrombin, thereby hindering fibrinogen from becoming fibrin, thereby playing the anticoagulation effect, in order to increase the purity of heparin sodium, usually uses the precipitate filter mechanism to take out the impurities inside heparin sodium.

[0003] The Chinese patent document with the authorization announcement number CN222131185U discloses a high-purity heparin sodium fine filter mechanism, which belongs to the technical field of heparin sodium filtration and purification, and comprises a filter box. The inside of the filter box is provided with a collection box. The left and right sides of the filter box are both provided with a dismounting opening. The front and back of the filter box are both fixedly connected with a connecting block. The upper surface of each connecting block is fixedly connected with a hydraulic rod. The extension ends of the two hydraulic rods are fixedly connected with a connecting frame. The bottom surface of the connecting frame is fixedly connected with a guide column. The inside of the filter box is slidably connected with a filter frame. When the microporous filter plate moves downward, it forces the heparin sodium solution to pass through the two microporous filter plates and enter the upper part of the filter frame. The impurities inside the heparin sodium are blocked by the microporous filter plate, which allows the heparin sodium to be fine filtered without using the precipitation method to filter and remove the impurities in the heparin sodium solution, effectively increasing the filtration and purification efficiency of the heparin sodium solution.

[0004] In the above-mentioned prior art, when filtering the heparin sodium solution, there are few fine filter structures, which causes poor filtering effect and makes it inconvenient to disassemble and replace the fine filter components. Therefore, it is necessary to develop a new high-purity heparin sodium fine filter mechanism. UTILITY MODEL CONTENTS

[0005] The utility model aims at providing a high-purity heparin sodium fine filter mechanism to solve the problem of few fine filter structures in the prior art, which causes poor filtering effect and makes it inconvenient to disassemble and replace the fine filter components.

[0006] To achieve the above object, the utility model provides the following technical scheme: A high -purity heparin sodium fine filter mechanism, including liquid inlet filter tube, one end of liquid inlet filter tube is connected with first fine filter jar through pipeline seal, one end of first fine filter jar is connected with second fine filter jar through filter pipeline seal, the inside of first fine filter jar and second fine filter jar all is provided with fine filter subassembly, fine filter subassembly is detachable structure, one end of second fine filter jar is provided with liquid outlet filter tube.

[0007] Preferably, the inside of the liquid inlet filter tube, the filter pipeline and the liquid outlet filter tube is installed with a fine filter screen structure, and the liquid inlet filter tube, the filter pipeline and the liquid outlet filter tube are all installed with a switch valve.

[0008] Preferferably, the fine filter subassembly includes an ultrafiltration membrane body structure, a fine filter layer and a nanofiltration membrane structure, the ultrafiltration membrane body structure is located directly above the fine filter layer, and the nanofiltration membrane structure is located directly below the fine filter layer.

[0009] Preferably, the upper end surfaces of the first fine filter jar and the second fine filter jar are both provided with a sealing cover plate, and the side surface of the sealing cover plate is sealingly fixed with the first fine filter jar and the second fine filter jar through a locking mechanism.

[0010] Preferably, the lower end surface of the sealing cover plate is fixedly connected with the fine filter subassembly through a fixed guide rod.

[0011] Preferably, the liquid inlet filter tube is sealingly connected with a first filter branch pipe and a second filter branch pipe through a first three-way pipe, and the first filter branch pipe and the second filter branch pipe are both provided with a filter pump and a water pressure gauge.

[0012] Preferably, one end of the first filter branch pipe and the second filter branch pipe is sealingly connected with the first fine filter jar through a second three-way pipe.

[0013] Compared with the prior art, the utility model has the advantages that:

[0014] The utility model discloses a two fine filter jar structure can carry out layer by layer depth fine filter operation to the impurity particle in heparin sodium solution, has the advantage that the filtering effect is good, and the fine filter subassembly is convenient to take and replace and cleaning operation, and the fine filter screen structure is installed in the inside of the liquid inlet end and the liquid outlet end pipeline of solution, can further fine filter operation to heparin sodium solution, can effectively remove the impurity particle in heparin sodium solution, guarantees the high purity and the impurity of heparin sodium solution, improves the forming quality of heparin sodium solution. BRIEF DESCRIPTION OF DRAWINGS

[0015] Fig. 1 It is internal installation structure schematic drawing of the utility model;

[0016] Fig. 2 It is external structure schematic drawing of the utility model;

[0017] Fig. 3 The overall front view of the utility model.

[0018] In the figure: 1, liquid inlet filter pipe; 2, precision filter screen structure; 3, first precision filter tank; 4, precision filter assembly; 5, ultrafiltration membrane body structure; 6, precision filter filter layer; 7, nanofiltration membrane structure; 8, sealing cover plate; 9, locking mechanism; 10, fixed guide rod; 11, second precision filter tank; 12, liquid outlet filter pipe; 13, on-off valve; 14, filter pipeline; 15, water pressure gauge; 16, second filter branch pipe; 17, first tee pipe; 18, first filter branch pipe; 19, filter pump; 20, second tee pipe. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments.

[0020] Please refer to Figs. 1-3 The utility model provides an embodiment: a kind of high-purity heparin sodium precision filter mechanism, including liquid inlet filter pipe 1, and the one end of liquid inlet filter pipe 1 is connected with first precision filter tank 3 by pipeline sealing, and the one end of first precision filter tank 3 is connected with second precision filter tank 11 by filter pipeline 14 sealing, and the inside of first precision filter tank 3 and second precision filter tank 11 is all provided with precision filter assembly 4, and precision filter assembly 4 is detachable structure, and the one end of second precision filter tank 11 is provided with liquid outlet filter pipe 12.

[0021] Further, the inside of liquid inlet filter pipe 1, filter pipeline 14 and liquid outlet filter pipe 12 is all installed with precision filter screen structure 2, it is convenient to carry out filter operation to the heparin sodium solution entering the inside of each pipeline, and the on-off valve 13 is installed on liquid inlet filter pipe 1, filter pipeline 14 and liquid outlet filter pipe 12, for on-off control to the liquid flow in the inside of pipeline.

[0022] Further, precision filter assembly 4 includes ultrafiltration membrane body structure 5, precision filter filter layer 6 and nanofiltration membrane structure 7, ultrafiltration membrane body structure 5 is located directly above precision filter filter layer 6, and nanofiltration membrane structure 7 is located directly below precision filter filter layer 6, by being provided with ultrafiltration membrane body structure 5, precision filter filter layer 6 and nanofiltration membrane structure 7, it is convenient to carry out depth precision filter operation to the tiny impurity particles of heparin sodium solution, and the pore size of each precision filter membrane is nanometer level, and tiny impurity particles cannot pass through the pore on its surface.

[0023] Further, the upper end surface of first precision filter tank 3 and second precision filter tank 11 is all provided with sealing cover plate 8, and the side surface of sealing cover plate 8 is sealed and fixed with first precision filter tank 3 and second precision filter tank 11 by locking mechanism 9, to facilitate the quick sealing and fixing between sealing cover plate 8 and precision filter tank.

[0024] Further, the lower end surface of the sealing cover plate 8 is fixedly connected with the fine filter assembly 4 through the fixed guide rod 10, so as to facilitate opening of the sealing cover plate 8, and facilitate lifting of the fine filter assembly 4, thereby facilitating quick replacement and cleaning of the fine filter assembly 4.

[0025] Further, the liquid inlet filter pipe 1 is sealingly connected with the first filter branch pipe 18 and the second filter branch pipe 16 through the first three-way pipe 17, the first filter branch pipe 18 and the second filter branch pipe 16 are both provided with a filter pump 19 and a water pressure gauge 15, one end of the first filter branch pipe 18 and the second filter branch pipe 16 is sealingly connected with the first fine filter tank 3 through the second three-way pipe 20, by opening the filter pump 19, external heparin sodium solution can be drawn into the first fine filter tank 3 through the liquid inlet filter pipe 1 for fine filtering operation, by providing the three-way pipe, convenient and quick sealing connection between the filter branch pipe assemblies can be achieved, and the filter branch pipe assemblies have the advantages of convenient and quick assembly and disassembly.

[0026] Working principle: in use, by opening the filter pump 19, external heparin sodium solution can be drawn into the first fine filter tank 3 through the liquid inlet filter pipe 1 for fine filtering operation, one end of the first fine filter tank 3 is sealingly connected with the second fine filter tank 11 through the filter pipe 14, the interiors of the first fine filter tank 3 and the second fine filter tank 11 are both provided with a fine filter assembly 4, the fine filter assembly 4 includes an ultrafiltration membrane body structure 5, a fine filter layer 6 and a nanofiltration membrane structure 7, by providing the ultrafiltration membrane body structure 5, the fine filter layer 6 and the nanofiltration membrane structure 7, fine and deep filtering operation of small impurity particles in the heparin sodium solution can be facilitated, the pore sizes of the fine filter membranes are all nanometer level, small impurity particles cannot pass through the pores on the surface of the fine filter membranes, and good fine filtering effect is achieved, the lower end surface of the sealing cover plate 8 is fixedly connected with the fine filter assembly 4 through the fixed guide rod 10, so as to facilitate opening of the sealing cover plate 8, and facilitate lifting of the fine filter assembly 4, thereby facilitating quick replacement and cleaning of the fine filter assembly 4, finally, by opening the switch valve 13, the fine-filtered heparin sodium solution is discharged from the liquid outlet filter pipe 12.

[0027] It should be noted that, in the present text, relational terms such as first and second and the like can only be used to distinguish one entity or operation from another entity or operation, without necessarily requiring or implying any such actual relationship or order between these entities or operations. Moreover, the terms "comprises", "comprising" or any other variant thereof are intended to cover non-exclusive inclusions, so that a process, method, article or apparatus that includes a list of elements not only includes those elements, but also includes other elements not explicitly listed, or inherent to such a process, method, article or apparatus.

[0028] The standard parts used in the present application file can be purchased from the market, the specific connection mode of each part is connected by using the conventional means such as bolt, rivet, welding and the like in the prior art, and the mechanical, parts and equipment adopt the conventional type in the prior art, plus the circuit connection adopts the conventional connection mode in the prior art, which will not be described in detail here.

[0029] Although the embodiments of the present application have been shown and described, it can be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to the embodiments without departing from the principles and spirit of the present application, and the scope of the present application is defined by the appended claims and their equivalents.

Claims

1. A high-purity heparin sodium fine filter mechanism comprising a liquid inlet filter tube (1), characterized in that, One end of the inlet filter pipe (1) is sealed to a first fine filter tank (3) through a pipeline. One end of the first fine filter tank (3) is sealed to a second fine filter tank (11) through a filter pipe (14). The first fine filter tank (3) and the second fine filter tank (11) are both equipped with a fine filter assembly (4). The fine filter assembly (4) is a detachable structure. One end of the second fine filter tank (11) is equipped with a drain filter pipe (12).

2. The high purity heparin sodium filtering mechanism according to claim 1, characterized in that: The inlet filter pipe (1), the filter pipe (14) and the outlet filter pipe (12) are all equipped with fine filter screen structures (2), and the inlet filter pipe (1), the filter pipe (14) and the outlet filter pipe (12) are all equipped with switch valves (13).

3. The high purity heparin sodium filtering mechanism according to claim 1, characterized in that: The fine filtration assembly (4) includes an ultrafiltration membrane structure (5), a fine filtration layer (6), and a nanofiltration membrane structure (7). The ultrafiltration membrane structure (5) is located directly above the fine filtration layer (6), and the nanofiltration membrane structure (7) is located directly below the fine filtration layer (6).

4. The high-purity heparin sodium filtration mechanism according to claim 1, characterized in that: The upper surfaces of the first fine filter tank (3) and the second fine filter tank (11) are provided with sealing cover plates (8), and the side surfaces of the sealing cover plates (8) are sealed and fixed to the first fine filter tank (3) and the second fine filter tank (11) by locking mechanism (9).

5. The high-purity heparin sodium filtration mechanism according to claim 4, characterized in that: The lower surface of the sealing cover (8) is fixedly connected to the fine filter assembly (4) via a fixed guide rod (10).

6. The high-purity heparin sodium filtration mechanism according to claim 1, characterized in that: The inlet filter tube (1) is sealed to a first filter branch tube (18) and a second filter branch tube (16) through a first three-way tube (17). A filter pump (19) and a water pressure gauge (15) are installed on both the first filter branch tube (18) and the second filter branch tube (16).

7. The high-purity heparin sodium filtration mechanism according to claim 6, characterized in that: One end of the first filter branch pipe (18) and the second filter branch pipe (16) are sealed to the first fine filter tank (3) through the second tee pipe (20).

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