Precipitation separation device for elastin gel preparation
By using a cleaning ring and filtration mechanism in the precipitation separation device during the preparation of elastin gel, the problem of gel adhesion to the inner wall of the container was solved, achieving efficient gel recovery and pure separation of the aqueous solution.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- JIANGSU PEPTIDIN BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-12-31
- Publication Date
- 2026-05-15
AI Technical Summary
During the preparation of elastin gel, the gel tends to adhere to the inner wall of the container, resulting in a low recovery rate during the subsequent aqueous phase gel separation.
Design a sedimentation separation device, including a sedimentation cylinder, a cleaning ring, and a filtration mechanism. The cleaning ring is driven by a drive mechanism to move downwards, scraping off the gel adhering to the inner wall of the sedimentation cylinder, and the gel particles are intercepted by the filtration mechanism to ensure that the gel particles settle to the bottom of the container.
This improves the recovery efficiency of the gel, avoids mixing of the gel with the aqueous solution, and ensures efficient recovery of gel particles and purity of the aqueous solution.
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Figure CN122032196A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of gel separation and extraction technology, and more specifically, to a precipitation separation apparatus for the preparation of elastin gels. Background Technology
[0002] Elastin gel, as a material with excellent elasticity and biocompatibility, is widely used in tissue engineering, drug delivery systems and biomedical devices. The preparation of elastin gel usually involves precipitating and solidifying elastin solution under specific conditions to obtain the desired three-dimensional network structure.
[0003] However, during the static sedimentation process in the preparation of elastin gel, the elastin gel particles gradually sink to the bottom of the container under the action of gravity. However, due to the viscosity and elasticity of the gel, it will come into contact with and rub against the inner wall of the sedimentation container during the descent, causing some gel to adhere to the inner wall of the container. When the aqueous solution and elastin gel are separated in the later stage, the attached gel is easily discharged with the discharged aqueous solution, resulting in a low elastin gel recovery rate.
[0004] To address the aforementioned issues, a precipitation separation device for the preparation of elastin gels is proposed. Summary of the Invention
[0005] (a) Technical problems to be solved
[0006] To address the problems existing in the prior art, the present invention provides a precipitation separation device for the preparation of elastin gel, thereby solving the problem mentioned in the background art that during the static precipitation process of elastin gel preparation, the gel easily adheres to the inner wall of the container, resulting in a low elastin gel recovery rate during subsequent aqueous phase gel separation.
[0007] (II) Technical Solution
[0008] To achieve the above objectives, the present invention provides the following technical solution: a precipitation separation device for preparing elastin gel, comprising a precipitation cylinder, a drain port provided above the circumferential side wall of the precipitation cylinder, a cleaning ring for cleaning attached gel provided inside the precipitation cylinder, and a filter mechanism for intercepting gel provided at the center of the cleaning ring, the filter mechanism and the cleaning ring being rotatably connected, and a drive mechanism for driving the cleaning ring to slide up and down provided at the top of the cleaning ring.
[0009] The present invention is further configured such that the driving mechanism includes connecting rods arranged in a ring array at the top of the cleaning ring, and the connecting rods are arranged in an L-shape. One end of the horizontal section of the L-shape of the connecting rod is fixedly connected to a threaded rod. The threaded rod and the connecting rod form an inverted U-shaped structure, and the connecting rod and the threaded rod are respectively arranged on the inner and outer sides of the side wall of the sedimentation cylinder.
[0010] The present invention is further configured such that the top end of the sedimentation cylinder is provided with an inner and outer extending flange, and the inner extending flange of the sedimentation cylinder is provided with a guide hole, the guide hole being movably inserted into the connecting rod, and a first gear being rotatably installed on the outer extending flange of the sedimentation cylinder, the first gear being disposed through the flange, the shaft of the first gear being provided with a threaded groove, and the threaded groove and the threaded rod being threadedly matched.
[0011] The invention is further configured such that a toothed ring is rotatably mounted below the flange, and toothed grooves are provided both inside and outside the toothed ring; multiple sets of the first gears are arranged in a circular array, and the inner toothed groove of the toothed ring meshes with the multiple sets of the first gears in the circular array; a motor bracket is fixedly mounted on the circumferential side wall of the sedimentation cylinder, and a drive motor is fixedly mounted on the motor bracket; a second gear is fixedly mounted on the output shaft of the drive motor, and the second gear meshes with the outer toothed groove of the toothed ring.
[0012] The present invention is further configured such that the filtration mechanism includes a filter plate rotatably mounted on the cleaning ring, a filter hole formed on the filter plate, and a one-way filtration component movably disposed on the filter hole;
[0013] The filter plate and the cleaning ring are rotatably connected.
[0014] The present invention is further configured such that the unidirectional filter assembly consists of a blocking block, an insert rod, and a limiting rod, wherein the blocking block and the limiting rod are respectively disposed at both ends of the insert rod, the insert rod is movably inserted into the filter hole, and the length of the insert rod is greater than the thickness of the filter plate, the blocking block is located above the filter plate, and the limiting rod is located below the filter plate, the length of the limiting rod is greater than the diameter of the filter hole, and the diameter of the insert rod is smaller than the diameter of the filter hole.
[0015] The present invention is further configured such that the cleaning ring is composed of a ring body, a cleaning scraper, a sealing ring, and a guide plate. The sealing ring is sleeved on the outside of the ring body, and the top end of the ring body is fixedly connected to one end of the connecting rod. The cleaning scraper and the guide plate are disposed on both sides of the bottom end of the ring body, and the cross-section of the cleaning scraper and the guide plate is arranged in a figure-eight shape. The ring body, the cleaning scraper, and the guide plate constitute a buffer cavity.
[0016] The present invention is further configured such that the unidirectional filter assembly is movably disposed in the central filter hole of the filter plate, the unidirectional filter assembly is composed of a sealing plate, a guide rod and a stop block, the guide rod movably passes through the filter hole in the center of the filter plate, and the sealing plate and the stop block are respectively disposed at both ends of the guide rod, the sealing plate is disposed above the filter plate and the stop block is disposed below the filter plate.
[0017] The present invention is further configured such that when the baffle is attached to the filter plate, a temporary cavity is formed between the sealing plate and the filter plate, and a separation flow channel is formed between the outer ring of the sealing plate and the guide inclined plate.
[0018] The present invention is further configured such that the sealing plate is sealed and matched with the inner wall of the guide inclined plate when it is attached to the filter plate.
[0019] (III) Beneficial Effects
[0020] Compared with the prior art, the present invention provides a precipitation separation device for the preparation of elastin gels, which has the following beneficial effects:
[0021] 1. This invention, by setting a cleaning ring and a filtration mechanism inside the sedimentation tank, uses a driving mechanism to push the cleaning ring downwards, effectively scraping off the elastin gel attached to the inner wall of the sedimentation tank. At the same time, the filtration mechanism moves downwards with the cleaning ring, allowing the aqueous solution to pass through while intercepting the gel particles, preventing the gel particles from floating and rising in the aqueous solution, ensuring that the gel particles can settle smoothly to the bottom of the container, and improving the gel recovery efficiency.
[0022] 2. The cleaning ring of the present invention effectively collects the scraped gel through the buffer cavity formed by the cleaning scraper and the guide inclined plate, avoiding the filter pore blockage problem caused by the gel moving in opposite directions with the downward filter plate. At the same time, the sealing plate and the filter plate form a temporary cavity, and the sealing plate and the guide inclined plate form a separation channel, which further improves the separation effect between the aqueous solution and the gel particles. Even if some gel blocks the filter pores and passes through the filter pores, it can be filtered and intercepted by the separation channel in the temporary cavity, thereby ensuring the purity of the aqueous solution and the efficient recovery of gel particles. Attached Figure Description
[0023] Figure 1 This is a schematic diagram of the overall structure of a precipitation separation device used for the preparation of elastin gels.
[0024] Figure 2 This is a cross-sectional view of the sedimentation tank.
[0025] Figure 3 This is a structural diagram of the drive mechanism, cleaning ring, and filter mechanism.
[0026] Figure 4 This is an exploded view of the filtration mechanism.
[0027] Figure 5 This is a schematic diagram of the unidirectional filter component in Example 1.
[0028] Figure 6 This is a schematic diagram of the cleaning ring structure in Example 2.
[0029] Figure 7This is a schematic diagram of the cleaning ring and filter mechanism in Example 2.
[0030] Figure 8 This is a schematic diagram showing the positional structure between the sealing plate, the filter plate, and the cleaning ring when the filtration mechanism moves downward in Example 2.
[0031] Figure 9 for Figure 8 Enlarged structural diagram at point A in the middle.
[0032] Figure 10 This is a schematic diagram showing the positional structure between the sealing plate and the guide ramp when the filter mechanism moves upward in Example 2.
[0033] In the diagram: 1. Sedimentation cylinder; 11. Drain outlet; 12. Flange; 13. Guide hole; 14. Motor bracket; 2. Cleaning ring; 21. Ring body; 22. Cleaning scraper; 23. Sealing ring; 24. Buffer chamber; 25. Guide inclined plate; 3. Filtration mechanism; 31. Filter plate; 32. Filter hole; 33. One-way filter assembly; 331. Blocking block; 332. Insert rod; 333. Limiting rod; 334. Sealing plate; 335. Guide rod; 336. Stop block; 4. Drive mechanism; 41. Connecting rod; 42. Threaded rod; 43. First gear; 44. Threaded groove; 45. Gear ring; 46. Second gear; 47. Drive motor; 5. Temporary chamber; 6. Separation channel. Detailed Implementation
[0034] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The present invention will now be described in detail with reference to the accompanying drawings and embodiments.
[0035] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.
[0036] In this invention, unless otherwise stated, the directional terms such as "up" and "down" generally refer to the directions shown in the accompanying drawings, or to the vertical, perpendicular, or gravitational direction; similarly, for ease of understanding and description, "left" and "right" generally refer to the left and right shown in the accompanying drawings; "inner" and "outer" refer to the inner and outer contours of each component itself, but the above directional terms are not intended to limit this invention.
[0037] Example 1, please refer to Figure 1 - Figure 5A precipitation separation device for preparing elastin gel includes a precipitation cylinder 1, a drain port 11 is provided above the circumferential side wall of the precipitation cylinder 1, a cleaning ring 2 for cleaning the attached gel is provided inside the precipitation cylinder 1, and a filter mechanism 3 for intercepting the gel is provided at the center of the cleaning ring 2. The filter mechanism 3 and the cleaning ring 2 are rotatably connected, and a drive mechanism 4 for driving the cleaning ring 2 to slide up and down is provided at the top of the cleaning ring 2.
[0038] During the preparation of elastin gel, the gel particles gradually sink under gravity during the static sedimentation process. Due to the viscosity and elasticity of the gel, it comes into contact with and rubs against the inner wall of the sedimentation cylinder 1 during the descent. Some of the gel adheres to the inner wall of the sedimentation cylinder 1. After the static sedimentation separation is completed, an upper aqueous phase solution and a lower gel are formed, as well as some gel residue on the inner wall of the sedimentation cylinder 1. At this point, it is necessary to drain the upper aqueous phase solution and retain the lower gel to obtain the desired elastin gel. However, if the gel adhering to the inner wall of the sedimentation cylinder 1 is not cleaned to the lower layer when draining the upper aqueous phase solution, some of the gel adhering to the inner wall of the sedimentation cylinder 1 will be drained along with the aqueous phase solution, resulting in low efficiency in the preparation of elastin gel.
[0039] Therefore, by providing a cleaning ring 2 and a filter mechanism 3 inside the sedimentation cylinder 1, the mixed solution before sedimentation is allowed to settle and separate into layers inside the sedimentation cylinder 1. Then, the cleaning ring 2 is pushed down by the drive mechanism 4, so that the cleaning ring 2 scrapes off the elastin gel attached to the inner wall of the sedimentation cylinder 1. The scraped-off gel continues to settle downward under the action of gravity.
[0040] Furthermore, when the cleaning ring 2 moves downward, it drives the filter mechanism 3 downward, allowing the aqueous solution to pass through the filter mechanism 3. The scraped elastin gel is intercepted by the filter mechanism 3, which prevents the scraped elastin gel from floating in the aqueous solution and rising due to solution disturbance. At the same time, as the filter mechanism 3 moves downward, the scraped elastin gel is simultaneously driven to settle downward, which is faster than conventional static sedimentation.
[0041] Specifically, such as Figure 1-3 As shown, the driving mechanism 4 includes connecting rods 41 arranged in a ring array at the top of the cleaning ring 2, and the connecting rods 41 are L-shaped. One end of the horizontal section of the L-shaped connecting rod 41 is fixedly connected to a threaded rod 42. The threaded rod 42 and the connecting rod 41 form an inverted U-shaped structure, and the connecting rod 41 and the threaded rod 42 are respectively arranged on the inner and outer sides of the side wall of the sedimentation cylinder 1.
[0042] Furthermore, the top of the sedimentation cylinder 1 is provided with an inwardly and outwardly extending flange 12, and a guide hole 13 is provided on the inwardly extending flange 12 of the sedimentation cylinder 1. The guide hole 13 is movably inserted into the connecting rod 41. A first gear 43 is rotatably mounted on the outwardly extending flange 12 of the sedimentation cylinder 1, and the first gear 43 is disposed through the flange 12. The axis of the first gear 43 is formed in a threaded groove 44, and the threaded groove 44 and the threaded rod 42 are threadedly matched. Multiple sets of the first gear 43 are arranged in a circular array, the number of which corresponds to the number of threaded rods 42. The quantity, through the setting of multiple sets, makes the connecting rod 41 push the cleaning ring 2 downward more stable. A toothed ring 45 is rotatably installed below the flange 12, and the toothed ring 45 has tooth grooves on both the inner and outer sides. The inner tooth groove of the toothed ring 45 meshes with multiple sets of first gears 43 in a ring array. A motor bracket 14 is fixedly installed on the circumferential side wall of the sedimentation cylinder 1, and a drive motor 47 is fixedly installed on the motor bracket 14. A second gear 46 is fixedly installed on the output shaft of the drive motor 47, and the second gear 46 meshes with the outer tooth groove of the toothed ring 45.
[0043] By starting the drive motor 47, the second gear 46 is driven to rotate, thereby causing the second gear 46 to mesh with the gear ring 45. After the gear ring 45 rotates, it meshes with the first gear 43 through the inner tooth groove, causing the first gear 43 to rotate. The rotation of the first gear 43 drives the threaded rod 42 to move downward through the threaded groove 44. When the threaded rod 42 moves downward, it simultaneously drives the connecting rod 41 to move downward, thereby causing the cleaning ring 2, which is fixedly connected to the connecting rod 41, to move downward, thereby scraping off the elastin gel attached to the inner wall of the sedimentation cylinder 1.
[0044] As the cleaning ring 2 moves downward, it causes the filter mechanism 3 to move downward as well. Figure 4As shown, the filtration mechanism 3 includes a filter plate 31 rotatably mounted on the cleaning ring 2, filter holes 32 formed on the filter plate 31, and a one-way filter assembly 33 movably disposed on the filter holes 32. The filter plate 31 and the cleaning ring 2 are rotatably connected, allowing the mixed solution before sedimentation to be easily added into the sedimentation cylinder 1 by opening the filter plate 31. It should be noted that the liquid level of the mixed solution added into the sedimentation cylinder 1 should not be higher than that of the filtration mechanism 3. After adding the mixed solution, the filter plate 31 is rotated to close. A locking mechanism (not shown in the figure) is provided between the end of the filter plate 31 away from the rotatable connection and the cleaning ring 2, so that the filter plate 31 remains horizontal. Furthermore, during the subsequent downward movement, when the aqueous phase solution passes through the filter holes 32 of the filter plate 31, the filter plate 31 will not rotate and cause damage. The opening causes the gel to mix and move upward with the liquid flow. When the one-way filter component 33 moves downward in the aqueous solution, the downward force and the aqueous solution form an opposite force, causing the one-way filter component 33 to move upward and open the filter hole 32. This allows the aqueous solution to pass through the filter hole 32 and enter the upper layer of the filter plate 31. When the filter plate 31 moves downward to near the boundary between the aqueous solution and the gel, the drive motor 47 drives in the opposite direction, causing the connecting rod 41 to move upward, thereby driving the cleaning ring 2 to move upward. This causes the one-way filter component 33 installed on the filter hole 32 to come into contact with the aqueous solution above. Under the action of gravity of the aqueous solution, the one-way filter component 33 moves downward to fit and seal the filter hole 32. At this time, the filter plate 31 sealing the filter hole 32 becomes a closed plate, which can lift and discharge the aqueous solution above.
[0045] Specifically, such as Figure 5As shown, each filter hole 32 is movably equipped with a unidirectional filter assembly 33. The unidirectional filter assembly 33 consists of a blocking block 331, an insertion rod 332, and a limiting rod 333. The blocking block 331 and the limiting rod 333 are respectively located at both ends of the insertion rod 332. The insertion rod 332 is movably inserted into the filter hole 32, and the length of the insertion rod 332 is greater than the thickness of the filter plate 31. The blocking block 331 is located above the filter plate 31, and the limiting rod 333 is located below the filter plate 31. The length of the limiting rod 333 is greater than the diameter of the filter hole 32, and the diameter of the insertion rod 332 is smaller than the diameter of the filter hole 32. When the cleaning ring 2 moves the filter mechanism 3 downward, the cleaning ring 2 is responsible for scraping off the gel on the inner wall of the sedimentation cylinder 1. Before the filter mechanism 3 enters the aqueous solution, the filter hole 32 is in a blocked state. When the downward-moving filter mechanism 3 enters the upper aqueous phase solution, the filter plate 31 moves downward, allowing some of the aqueous phase solution to enter the filter hole 32. Then, the sealing plate is pushed upward, thereby opening the filter hole 32. After the filter hole 32 is opened, the aqueous phase solution enters the area above the filter plate 31 through the gap between the filter hole 32 and the insertion rod 332, and intercepts the gel below the filter plate 31. The downward movement stops when the cleaning ring 2 moves down to near the boundary between the aqueous phase solution and the gel. After the downward movement stops, the unidirectional filter assembly 33 sinks under the action of gravity, thereby causing the sealing block 331 to seal the filter hole 32. Then, the drive motor 47 drives in the opposite direction, and the cleaning ring 2 moves upward. The upper aqueous phase solution is lifted by the filter plate 31 that seals the filter hole 32 and then discharged from the drain port 11, which is connected to the collection box through a pipe.
[0046] Example 2, please refer to Figure 1 - Figure 10 In Example 1, when the cleaning ring 2 moves downward to clean the gel on the inner wall of the sedimentation cylinder 1, the scraped gel flows in the lower aqueous phase solution. Some of it moves in the opposite direction to the downward-moving filter plate 31, causing blockage of the filter pores 32. Then, driven by the downward movement of the cleaning ring 2, it is pushed above the filter plate 31 by the aqueous phase solution, resulting in waste of elastin gel. Therefore, the cleaning ring 2 and the one-way filtration assembly 33 are improved.
[0047] Specifically, such as Figure 6As shown, the cleaning ring 2 consists of a ring body 21, a cleaning scraper 22, a sealing ring 23, and a guide plate 25. The sealing ring 23 is sleeved on the outside of the ring body 21, and the top end of the ring body 21 is fixedly connected to one end of the connecting rod 41. The cleaning scraper 22 and the guide plate 25 are arranged on both sides of the bottom end of the ring body 21, and the cross-section of the cleaning scraper 22 and the guide plate 25 is arranged in a figure-eight shape. The ring body 21, the cleaning scraper 22, and the guide plate 25 form a buffer cavity 24. When the connecting rod 41 moves the ring body 21 downward... During this process, the cleaning scraper 22 scrapes off the gel from the inner wall of the sedimentation cylinder 1. Due to the tilt angle of the cleaning scraper 22, the scraped gel falls into the buffer chamber 24, preventing the scraped gel from moving in a corresponding manner with the downward-moving filter plate 31 and causing the filter pores 32 to become clogged. Then, under the action of the aqueous solution, it enters the aqueous solution above the filter plate 31. After the scraped gel enters the buffer chamber 24, as the downward-moving cleaning ring 2 moves down, the ring 21 pushes the gel downward synchronously, thereby reducing the mixing of the gel in the solution.
[0048] To prevent gel from clogging filter pores 32 in the lower layer solution, and to allow it to mix in the upper layer of the aqueous solution under the action of the aqueous solution, the unidirectional filtration component 33 is structurally improved, such as... Figure 7-10 As shown, the unidirectional filter assembly 33 is movably disposed in the central filter hole 32 on the filter plate 31. The unidirectional filter assembly 33 consists of a sealing plate 334, a guide rod 335, and a stop block 336. The guide rod 335 movably passes through the central filter hole 32 of the filter plate 31, and the sealing plate 334 and the stop block 336 are respectively disposed at both ends of the guide rod 335. The sealing plate 334 is disposed above the filter plate 31, and the stop block 336 is disposed below the filter plate 31.
[0049] Preferably, when the baffle 336 is attached to the filter plate 31, a temporary cavity 5 is formed between the sealing plate 334 and the filter plate 31, and a separation channel 6 is formed between the outer ring of the sealing plate 334 and the guide inclined plate 25. When the cleaning ring 2 drives the filter mechanism 3 to move downward, the aqueous solution will pass through the filter holes 32 on the filter plate 31, and then the sealing plate 334 will be lifted up, so that the baffle 336 is attached to the bottom of the filter plate 31, thereby forming the temporary cavity 5 and the separation channel 6. The aqueous solution passes through the filter holes 32 into the temporary cavity 5 and then enters the upper aqueous solution through the separation channel 6. If the lower gel blocks the filter holes 32, it will move upward under the action of the aqueous solution and enter the containment cavity first. It should be noted that the diameter of the separation channel 6 is smaller than that of the filter holes 32. At this time, the gel and aqueous solution in the containment cavity will be filtered and intercepted again as the cleaning ring 2 moves downward, so that the aqueous solution enters the upper layer and the gel is intercepted in the containment cavity.
[0050] When the sealing plate 334 is attached to the filter plate 31, it seals and matches the inner wall of the guide inclined plate 25. When the cleaning ring 2 drives the filter mechanism 3 to move upward, the downward gravity of the sealing plate 334 and the gravity of the aqueous phase solution on the upper layer of the filter plate 31 cause the sealing plate 334 to move downward and seal against the inner wall of the guide inclined plate 25. At the same time, it combines with the sealing ring 23 to adhere to the inner wall of the sedimentation cylinder 1. When it moves upward to discharge the aqueous phase solution, the leakage is reduced, and the content of the aqueous phase solution discharged upward is high, thereby improving the separation efficiency.
[0051] Of all the solutions mentioned above, those involving the connection between two components can be selected according to the actual situation, such as welding, bolt and nut connection, bolt or screw connection, or other known connection methods, which will not be elaborated here. For all the fixed connections mentioned above, welding is preferred. Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A precipitation separation device for the preparation of elastin gels, characterized in that: The device includes a sedimentation cylinder (1), a drain port (11) is provided above the circumferential side wall of the sedimentation cylinder (1), a cleaning ring (2) for cleaning the attached gel is provided inside the sedimentation cylinder (1), and a filter mechanism (3) for intercepting the gel is provided at the center of the cleaning ring (2). The filter mechanism (3) and the cleaning ring (2) are rotatably connected, and a drive mechanism (4) for driving the cleaning ring (2) to slide up and down is provided at the top of the cleaning ring (2).
2. The precipitation separation device for preparing elastin gel according to claim 1, characterized in that: The driving mechanism (4) includes connecting rods (41) arranged in a ring array at the top of the cleaning ring (2), and the connecting rods (41) are arranged in an L-shape. One end of the horizontal section of the L-shape of the connecting rods (41) is fixedly connected to a threaded rod (42). The threaded rod (42) and the connecting rod (41) form an inverted U-shaped structure, and the connecting rods (41) and the threaded rod (42) are respectively arranged on the inner and outer sides of the side wall of the sedimentation cylinder (1).
3. The precipitation separation device for preparing elastin gel according to claim 2, characterized in that: The sedimentation cylinder (1) has an inner and outer extending flange (12) at its top end. A guide hole (13) is provided on the inner extending flange (12) of the sedimentation cylinder (1). The guide hole (13) is movably inserted into the connecting rod (41). A first gear (43) is rotatably installed on the outer extending flange (12) of the sedimentation cylinder (1). The first gear (43) passes through the flange (12). The axis of the first gear (43) is opened in the threaded groove (44). The threaded groove (44) and the threaded rod (42) are threadedly matched.
4. The precipitation separation device for preparing elastin gel according to claim 3, characterized in that: A toothed ring (45) is rotatably mounted below the flange (12), and toothed grooves are provided inside and outside the toothed ring (45). Multiple sets of the first gears (43) are arranged in a ring array, and the toothed grooves inside the toothed ring (45) mesh with the multiple sets of the first gears (43) in the ring array. A motor bracket (14) is fixedly mounted on the circumferential side wall of the sedimentation cylinder (1), and a drive motor (47) is fixedly mounted on the motor bracket (14). A second gear (46) is fixedly mounted on the output shaft of the drive motor (47), and the second gear (46) meshes with the outer toothed groove of the toothed ring (45).
5. The precipitation separation device for preparing elastin gel according to claim 4, characterized in that: The filtration mechanism (3) includes a filter plate (31) rotatably mounted on the cleaning ring (2), a filter hole (32) opened on the filter plate (31), and a one-way filter assembly (33) movably disposed on the filter hole (32). The filter plate (31) and the cleaning ring (2) are rotatably connected.
6. The precipitation separation apparatus for preparing elastin gel according to claim 5, characterized in that: The unidirectional filter assembly (33) consists of a blocking block (331), an insert rod (332), and a limiting rod (333). The blocking block (331) and the limiting rod (333) are respectively disposed at both ends of the insert rod (332). The insert rod (332) is movably inserted into the filter hole (32). The length of the insert rod (332) is greater than the thickness of the filter plate (31). The blocking block (331) is located above the filter plate (31), and the limiting rod (333) is located below the filter plate (31). The length of the limiting rod (333) is greater than the diameter of the filter hole (32), and the diameter of the insert rod (332) is smaller than the diameter of the filter hole (32).
7. The precipitation separation device for preparing elastin gel according to claim 1, characterized in that: The cleaning ring (2) consists of a ring body (21), a cleaning scraper (22), a sealing ring (23), and a guide plate (25). The sealing ring (23) is fitted around the outside of the ring body (21), and the top of the ring body (21) is fixedly connected to one end of the connecting rod (41). The cleaning scraper (22) and the guide plate (25) are located on both sides of the bottom end of the ring body (21), and the cross-section of the cleaning scraper (22) and the guide plate (25) is arranged in a figure-eight shape. The ring body (21), the cleaning scraper (22), and the guide plate (25) constitute a buffer cavity (24).
8. The precipitation separation device for preparing elastin gel according to claim 5, characterized in that: The unidirectional filter assembly (33) is movably disposed in the central filter hole (32) on the filter plate (31). The unidirectional filter assembly (33) consists of a sealing plate (334), a guide rod (335) and a stop block (336). The guide rod (335) movably passes through the filter hole (32) in the center of the filter plate (31). The sealing plate (334) and the stop block (336) are respectively disposed at both ends of the guide rod (335). The sealing plate (334) is disposed above the filter plate (31), and the stop block (336) is disposed below the filter plate (31).
9. A precipitation separation apparatus for preparing elastin gel according to claim 8, characterized in that: When the baffle (336) is attached to the filter plate (31), a temporary cavity (5) is formed between the sealing plate (334) and the filter plate (31), and a separation flow channel (6) is formed between the outer ring of the sealing plate (334) and the guide inclined plate (25).
10. A precipitation separation apparatus for preparing elastin gel according to claim 9, characterized in that: When the sealing plate (334) is attached to the filter plate (31), it is sealed and matched with the inner wall of the guide plate (25).