Eight-linked PCR (Polymerase Chain Reaction) plate device capable of realizing rapid sample change

Abstract

The utility model discloses an eight-linked PCR (Polymerase Chain Reaction) plate device capable of realizing rapid sample change, which comprises a body, and a plurality of placing grooves are formed in the surface of the body; the top surface of the body is rotatably connected with a cover plate, a groove is formed below the placement groove, connecting grooves are symmetrically formed in the two sides of the placement groove, and second telescopic rods are fixedly mounted in the connecting grooves. According to the eight-linked PCR plate taking device, the eight-linked PCR plate can be conveniently taken by an experimenter, so that the problems that the experimenter is unfamiliar with an operation process or is not skilled enough in technique, the sample replacement operation cannot be accurately and quickly completed, experimental errors are increased, and even experimental failures are caused are solved; a single PCR reaction tube is connected with a row of PCR reaction tubes, so that the waste of the PCR reaction tubes is avoided.

Description

TECHNICAL FIELD

[0001] The utility model relates to experimental equipment technical field, concretely is a kind of eight PCR plate device of realizing quick sample change. BACKGROUND

[0002] Eight PCR plate is a kind of consumables commonly used in polymerase chain reaction experiment, usually by 8 independent PCR reaction tube is formed, in strip form arrangement and interconnect, facilitate in one experiment simultaneously 8 PCR reactions, while the reaction tube in each PCR plate is independent space, liquid leakage and cross contamination between each other do not occur, ensure that each reaction can be carried out in independent, stable environment, to realize the rapid heat transfer, eight PCR plate usually adopts thin wall design.Thin wall structure can make heat rapidly and uniformly transmitted to the inside of reaction tube, make reaction system reach the temperature set in short time, improve the efficiency and specificity of PCR reaction, while also help to reduce the temperature difference between different reaction tubes, ensure the consistency of experimental results, PCR plate is usually equipped with the tube cover matched with it, and tube cover can tightly seal reaction tube, prevent the evaporation of liquid and the entry of external pollutants during reaction.And, the size and specification design of eight PCR plate meet the requirements of most PCR instruments, can be directly placed into instrument and react, with good compatibility, but PCR reaction tube in prior art may cause eight PCR plate to be inconvenient to take when sample change, and if experimental personnel are not familiar with operation process or skill is not enough skilled, may not accurately, quickly complete sample change operation, instead, it will increase experimental error, even lead to the situation of experimental failure.

[0003] A kind of eight PCR plate device of realizing quick sample change is presented, to solve the problems presented in the above. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a kind of eight PCR plate device of realizing quick sample change, to solve the problems presented in the above background art that PCR reaction tube in prior art may cause eight PCR plate to be inconvenient to take when sample change, and if experimental personnel are not familiar with operation process or skill is not enough skilled, may not accurately, quickly complete sample change operation, instead, it will increase experimental error, even lead to the situation of experimental failure.

[0005] To achieve the above object, the utility model provides the following technical scheme: a kind of eight PCR plate device of realizing quick sample change, including body, the surface of the body is equipped with a plurality of placing grooves;

[0006] The top surface of the body is rotatably connected with a cover plate, a groove is arranged below the placing groove, connecting grooves are symmetrically arranged on both sides of the placing groove, a second telescopic rod is fixedly installed in the connecting groove, a compression spring is sleeved on the surface of the second telescopic rod, the top surface of the compression spring is fixedly connected with the connecting groove, the bottom surface of the compression spring is fixedly connected with a clamping plate, and the bottom surface of the second telescopic rod is fixedly connected with the clamping plate.

[0007] Further comprising:

[0008] The inside of the groove is provided with a jacking assembly;

[0009] The jacking assembly comprises a fixed plate fixedly connected with the groove.

[0010] The side surface of the fixed plate away from the groove is fixedly connected with a connecting column.

[0011] Preferably, the side surface of the connecting column away from the fixed plate is fixedly connected with a bearing seat in the middle, the side surface of the bearing seat away from the connecting column is rotatably connected with a threaded rod, and the threaded rod penetrates through the body.

[0012] Preferably, the surface of the threaded rod is threadedly sleeved with a threaded plate, the side surface of the threaded plate close to the bottom is penetratingly connected with a limiting plate, one side surface of the limiting plate is fixedly connected with the fixed plate, and the other side surface of the limiting plate is fixedly connected with the groove.

[0013] Preferably, the surface of the threaded plate, the connecting column and the fixed plate is rotatably connected with a plurality of first telescopic rods, the top surface of the first telescopic rod is rotatably connected with a top plate, and a plurality of top grooves are arranged on the top surface of the top plate.

[0014] Preferably, a PCR reaction tube is penetratingly connected in the placing groove, and the bottom surface of the PCR reaction tube is clampingly connected with the top groove.

[0015] Preferably, the clamping plate is connected with the PCR reaction tube.

[0016] Preferably, rubber plates are symmetrically installed on the side surface of the PCR reaction tube close to the top, connecting plates are symmetrically installed on the other side surface of the PCR reaction tube close to the top, holes are arranged on the surface of the connecting plates, clamping blocks are clampingly connected in the holes, and the clamping blocks are fixedly connected with the rubber plates.

[0017] Compared with the prior art, the eight-PCR plate device capable of realizing rapid sample changing has the advantages that: the top-up assembly is arranged, so that the eight-PCR plate can be lifted by a distance before sample changing, and then the eight-PCR plate is convenient for an experimenter to take, thereby avoiding that the experimenter cannot accurately and quickly complete sample changing operation due to unfamiliar operation process or unskilled operation, and thus experimental error is increased, and even experimental failure occurs; meanwhile, the cooperation between the rubber plate, the connecting plate, the hole and the clamping block enables single PCR reaction tubes and rowed PCR reaction tubes to be connected, thereby avoiding waste of the PCR reaction tubes.

[0018] 1. The top-up assembly is arranged, and when sample changing of the eight-PCR plate is needed, the cover plate is slowly and stably opened, then the experimenter slowly rotates the threaded rod, the rotation of the threaded rod drives the movement of the threaded plate, the threaded plate and the limiting plate are in penetrating connection, the limiting plate and the groove and the fixed plate are in fixed connection, the threaded plate can move on the threaded rod under the limiting action of the limiting plate, the movement of the threaded plate drives the movement of the first extension rod rotatingly connected to the threaded plate, when the first extension rod on the threaded plate moves, the first extension rod constantly moves and rotates with the threaded plate, so that the first extension rod can top up the top plate, when the first extension rod on the threaded plate lifts the top plate, the connecting column and the first extension rod on the fixed plate also rotate with the rising of the top plate, and the rising of the top plate also stretches the first extension rod on the fixed plate, so that the first extension rod on the fixed plate can support the top plate, and after the top plate rises to a certain position, the top plate drives the rising of the PCR reaction tube, so that the PCR reaction tube is convenient for the experimenter to take after rising to a certain distance, thereby avoiding that the experimenter cannot accurately and quickly complete sample changing operation due to unfamiliar operation process or unskilled operation, and thus experimental error is increased, and even experimental failure occurs;

[0019] 2. By setting the second telescopic rod, compression spring and clamping plate, the PCR reaction tube is placed in the inside of the placing groove, so that the PCR reaction tube is pressed when entering the inside of the placing groove, so that the clamping plate moves, and the movement of the clamping plate presses the second telescopic rod and the compression spring, so that the compression spring deforms, and the compression spring exerts pressure on the clamping plate through the characteristics of the compression spring, so that the clamping plate can clamp and limit the PCR reaction tube, and the elastic force of the compression spring is small, so that the clamping plate does not deform when clamping the PCR reaction tube, and the bottom of the PCR reaction tube is clamped with the top groove of the jacking assembly after the PCR reaction tube is completely placed in the inside of the placing groove, so that the jacking assembly can support the PCR reaction tube, and the friction between the clamping plate and the PCR reaction tube is small, so that the jacking assembly can easily lift the PCR reaction tube when operating, thereby avoiding the breakage of the PCR reaction tube.

[0020] 3. By setting the rubber plate, connecting plate, hole and clamping block, when the single PCR reaction tube needs to be connected with the row of PCR reaction tubes, the two rubber plates are pressed towards the middle, so that the rubber plates deform, and after the rubber plates deform, the two rubber plates are placed in the middle of the two connecting plates, and after the two rubber plates are placed in the middle of the two connecting plates, the rubber plates restore to the original state through the elasticity of the rubber plates, and the clamping block on the rubber plate is clamped with the hole on the connecting plate, so that the connection between the PCR reaction tubes is completed, thereby avoiding the waste of the PCR reaction tubes. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 It is an overall top view structure schematic diagram of the utility model;

[0022] Figure 2 It is an overall internal structure schematic diagram of the utility model;

[0023] Figure 3 It is an overall internal structure schematic diagram of the utility model; Figure 1

[0024] Figure 4 It is an overall structure schematic diagram of the jacking assembly in the utility model;

[0025] Figure 5 It is an overall structure schematic diagram of the jacking assembly in the utility model; Figure 2

[0026] Figure 6 It is a body connecting structure schematic diagram in the utility model.

[0027] ​​In the figure: 1, the body; 2, the placing groove; 3, the cover plate; 4, the recess; 5, the jacking assembly; 501, the fixed plate; 502, the connecting column; 503, the bearing seat; 504, the threaded rod; 505, the threaded plate; 506, the limiting plate; 507, the first telescopic rod; 508, the top plate; 509, the top groove; 6, the connecting groove; 7, the second telescopic rod; 8, the compression spring; 9, the clamping plate; 10, the PCR reaction tube; 11, the rubber plate; 12, the connecting plate; 13, the hole; 14, the clamping block. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.

[0029] Please refer to Figures 1-6 The utility model provides technical scheme: a kind of eight PCR plate device of realizing quick sample change, including body 1, the surface of body 1 is equipped with several placing grooves 2;The top surface of body 1 is rotatably connected with cover plate 3, recess 4 is equipped below placing groove 2, connecting groove 6 is symmetrically equipped in the both sides of placing groove 2, second telescopic rod 7 is fixedly installed in the inside of connecting groove 6, compression spring 8 is equipped on the surface of second telescopic rod 7, the top surface of compression spring 8 is fixedly connected with connecting groove 6, the bottom surface of compression spring 8 is fixedly connected with clamping plate 9, the bottom surface of second telescopic rod 7 is fixedly connected with clamping plate 9;It further includes: recess 4 is provided with jacking assembly 5 in the inside;Wherein, jacking assembly 5 includes the fixed plate 501 fixedly connected with recess 4;Wherein, the side surface of fixed plate 501 away from recess 4 is fixedly connected with connecting column 502, as Figures 1-6 As shown, by setting jacking assembly 5, when eight PCR plate is changed, eight PCR plate is first jacked up a distance, so that it is convenient for experimental personnel to take eight PCR plate, so as to avoid that experimental personnel is not familiar with operation process or skill is not enough skilled, possibly unable to accurately and quickly complete sample change operation, instead, it will increase experimental error, even lead to experimental failure. Meanwhile, by setting the cooperation between rubber plate 11, connecting plate 12, hole 13 and clamping block 14, single PCR reaction tube 10 and row PCR reaction tube 10 can be connected, so as to avoid the waste of PCR reaction tube 10, and the model of body 1 is WX-PCE-JY30, and the working principle of body 1 is the same as prior art.

[0030] The connecting column 502 is fixedly connected with the bearing seat 503 in the middle of the side surface away from the fixed plate 501, the bearing seat 503 is rotatably connected with the threaded rod 504 away from the side surface of the connecting column 502, the threaded rod 504 is connected with the body 1, the surface of the threaded rod 504 is threadedly sleeved with the threaded plate 505, the side surface close to the bottom of the threaded plate 505 is connected with the limiting plate 506, the side surface of the limiting plate 506 is fixedly connected with the fixed plate 501, the other side surface of the limiting plate 506 is fixedly connected with the groove 4, the surface of the threaded plate 505, the connecting column 502 and the fixed plate 501 is rotatably connected with the first telescopic rod 507, the top surface of the first telescopic rod 507 is rotatably connected with the top plate 508, the top surface of the top plate 508 is provided with the top groove 509, the inside of the placing groove 2 is connected with the PCR reaction tube 10, and the bottom surface of the PCR reaction tube 10 is clampedly connected with the top groove 509, as shown in Figure 4 The threaded rod 504 is slowly rotated by the experimenter, the rotation of the threaded rod 504 can drive the movement of the threaded plate 505, the threaded plate 505 is connected with the limiting plate 506, the limiting plate 506 is fixedly connected with the groove 4 and the fixed plate 501, so that the threaded plate 505 can move on the threaded rod 504 under the limiting action of the limiting plate 506, the movement of the threaded plate 505 can drive the movement of the first telescopic rod 507 rotatably connected with the threaded plate 505, when the first telescopic rod 507 on the threaded plate 505 moves, the first telescopic rod 507 will rotate with the continuous movement of the threaded plate 505, so that the first telescopic rod 507 can lift the top plate 508, when the first telescopic rod 507 on the threaded plate 505 lifts the top plate 508, the first telescopic rod 507 on the connecting column 502 and the fixed plate 501 will also rotate with the rising of the top plate 508, the rising of the top plate 508 will also stretch the first telescopic rod 507 on the connecting column 502 and the fixed plate 501, so as to support the top plate 508, after the top plate 508 rises to a certain position, the PCR reaction tube 10 will be lifted, so that the PCR reaction tube 10 can be easily taken by the experimenter.

[0031] The clamping plate 9 is connected with the PCR reaction tube 10, as Figure 3As shown, when the PCR reaction tube 10 is placed inside the placement groove 2, the PCR reaction tube 10 will press the clamping plate 9 when entering the inside of the placement groove 2, so that the clamping plate 9 moves, and the movement of the clamping plate 9 will press the second telescopic rod 7 and the compression spring 8, so that the compression spring 8 deforms. Through the characteristics of the compression spring 8, the compression spring 8 will exert pressure on the clamping plate 9, so that the clamping plate 9 can clamp and limit the PCR reaction tube 10. At the same time, the elastic force of the compression spring 8 is small, so that the clamping plate 9 will not deform the PCR reaction tube 10 when clamping the PCR reaction tube 10.

[0032] The side surface of the PCR reaction tube 10 close to the top is symmetrically provided with a rubber plate 11, and the other side surface close to the top is symmetrically provided with a connecting plate 12. The surface of the connecting plate 12 is provided with a hole 13, and the inside of the hole 13 is clamped and connected with a clamping block 14. The clamping block 14 is fixedly connected with the rubber plate 11, as shown in Figure 5 、 6 When it is necessary to connect the single PCR reaction tube 10 with the connected PCR reaction tube 10, the two rubber plates 11 are pressed towards the middle, so that the rubber plates 11 deform. After the deformation of the rubber plates 11, the two rubber plates 11 are placed in the middle of the two connecting plates 12. After the two rubber plates 11 are placed in the middle of the two connecting plates 12, the rubber plates 11 restore to the original state through their elasticity, and the clamping block 14 on the rubber plate 11 can be clamped with the hole 13 on the connecting plate 12, so that the connection between the PCR reaction tubes 10 can be completed, thereby avoiding the waste of the PCR reaction tubes 10.

[0033] Working principle: Before using the eight-connected PCR plate device capable of realizing rapid replacement, the overall situation of the device needs to be checked to determine whether it can work normally. According to Figure 1 - Figure 6As shown, first by setting the jacking assembly 5, when the eight PCR plate needs to be replaced, the cover plate 3 is slowly and smoothly opened, then the experimental personnel slowly rotate the threaded rod 504, so that the rotation of the threaded rod 504 can drive the movement of the threaded plate 505, and the threaded plate 505 is connected with the limiting plate 506, the limiting plate 506 is fixedly connected with the groove 4 and the fixed plate 501, so that the threaded plate 505 can move on the threaded rod 504 under the limiting action of the limiting plate 506, and the movement of the threaded plate 505 drives the movement of the first telescopic rod 507 connected with the threaded plate 505, when the first telescopic rod 507 on the threaded plate 505 moves, the first telescopic rod 507 will rotate with the continuous movement of the threaded plate 505, so that the first telescopic rod 507 can play a role of jacking the top plate 508, and when the first telescopic rod 507 on the threaded plate 505 jacks the top plate 508, the first telescopic rod 507 on the connecting column 502 and the fixed plate 501 will also rotate with the rising of the top plate 508, and the rising of the top plate 508 will also stretch the first telescopic rod 507 on the connecting column 502 and the fixed plate 501, so that the first telescopic rod 507 can play a supporting role on the top plate 508, and when the top plate 508 rises to a certain position, it will drive the rising of the PCR reaction tube 10, so that the PCR reaction tube 10 can be easily taken by the experimental personnel after rising to a certain distance, thereby avoiding the situation that the experimental personnel cannot accurately and quickly complete the sample replacement operation due to unfamiliar operation process or unskilled operation method, thereby increasing experimental error and even causing experimental failure.

[0034] Secondly, by setting the second telescopic rod 7, the compression spring 8 and the clamping plate 9, when the PCR reaction tube 10 is placed in the inside of the placing groove 2, the PCR reaction tube 10 will extrude the clamping plate 9 when entering the inside of the placing groove 2, so that the clamping plate 9 moves, and the movement of the clamping plate 9 extrudes the second telescopic rod 7 and the compression spring 8, so that the compression spring 8 deforms, and the compression spring 8 exerts pressure on the clamping plate 9 through the characteristics of the compression spring 8, so that the clamping plate 9 can clamp and limit the PCR reaction tube 10, and the elastic force of the compression spring 8 is small, so that the clamping plate 9 does not deform the PCR reaction tube 10 when clamping the PCR reaction tube 10, and after the PCR reaction tube 10 is completely placed in the inside of the placing groove 2, the bottom of the PCR reaction tube 10 is clamped with the top groove 509 on the jacking assembly 5, so that the jacking assembly 5 can support the PCR reaction tube 10, and the friction between the clamping plate 9 and the PCR reaction tube 10 is small, so that the jacking assembly 5 can easily jack up the PCR reaction tube 10 when running, thereby avoiding the breakage of the PCR reaction tube 10.

[0035] Finally, by setting the rubber plate 11, the connecting plate 12, the hole 13 and the clamping block 14, when it is necessary to connect the single PCR reaction tube 10 with the row of PCR reaction tubes 10, the two rubber plates 11 are extruded towards the middle, so that the rubber plate 11 deforms, and after the deformation of the rubber plate 11, the two rubber plates 11 are placed in the middle of the two connecting plates 12, and after the two rubber plates 11 are placed in the middle of the two connecting plates 12, the rubber plate 11 restores to its original shape through its elasticity, and the clamping block 14 on the rubber plate 11 can be clamped with the hole 13 on the connecting plate 12, so that the connection between the PCR reaction tubes 10 can be completed, thereby avoiding the waste of the PCR reaction tubes 10.

[0036] Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments, or equivalently replace part of the technical features, and any modification, equivalent replacement, improvement, etc. within the spirit and principles of the utility model should be included in the protection scope of the utility model.

Claims

1. A kind of eight PCR plate devices of joint that can realize quick change, including body (1), the surface of the body (1) is provided with several placement grooves (2); The top surface of the body (1) is rotatably connected with cover plate (3), recess (4) is set in the lower of the placement groove (2), the two sides of the placement groove (2) are symmetrically provided with connecting groove (6), the inside of the connecting groove (6) is fixedly installed with second telescopic rod (7), the surface of the second telescopic rod (7) is equipped with compression spring (8), the top surface of the compression spring (8) is fixedly connected with connecting groove (6), the bottom surface of the compression spring (8) is fixedly connected with clamping plate (9), the bottom surface of the second telescopic rod (7) is fixedly connected with clamping plate (9); characterized in that Also include: The inside of the recess (4) is provided with top-up assembly (5); Wherein, top-up assembly (5) includes fixed plate (501) fixedly connected with recess (4); Wherein, the side surface of the fixed plate (501) away from recess (4) is fixedly connected with connecting column (502).

2. The eight-union PCR plate device capable of achieving fast swapping according to claim 1, wherein: The middle of the side surface of the connecting column (502) away from the fixed plate (501) is fixedly connected with bearing seat (503), the side surface of the bearing seat (503) away from the connecting column (502) is rotatably connected with threaded rod (504), and the threaded rod (504) is connected with the body (1) through.

3. The eight-union PCR plate device capable of achieving fast swapping according to claim 2, wherein: The surface of the threaded rod (504) is threadedly equipped with threaded plate (505), one side surface of the threaded plate (505) close to the bottom is connected with limit plate (506) through, the side surface of the limit plate (506) is fixedly connected with fixed plate (501), and the other side surface of the limit plate (506) is fixedly connected with recess (4).

4. The eight-union PCR plate device capable of achieving fast swapping according to claim 3, wherein: The surface of the threaded plate (505), connecting column (502) and fixed plate (501) is rotatably connected with several first telescopic rods (507), the top surface of the first telescopic rod (507) is rotatably connected with top plate (508), and the top surface of the top plate (508) is provided with several top grooves (509).

5. The eight-union PCR plate device capable of fast swapping of claim 4, wherein: The inside of the placement groove (2) is connected with PCR reaction tube (10) through, and the bottom surface of the PCR reaction tube (10) is connected with the top groove (509).

6. The eight-union PCR plate device capable of fast swapping of claim 1, wherein: The clamping plate (9) is connected with the PCR reaction tube (10) in place.

7. The eight-union PCR plate device capable of fast swapping of claim 5, wherein: The side surface of the PCR reaction tube (10) close to the top is symmetrically installed with rubber plate (11), the other side surface of the PCR reaction tube (10) close to the top is symmetrically installed with connecting plate (12), the surface of the connecting plate (12) is provided with hole (13), the inside of the hole (13) is connected with clamping block (14) in place, and the clamping block (14) is fixedly connected with rubber plate (11).

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