Purification device for medical material intermediates

Abstract

The utility model provides a medical material intermediate purification device which comprises a bottom frame, a reaction kettle body and a stirring machine, the reaction kettle body is fixedly connected to the top of the bottom frame, and the stirring machine penetrates between the bottoms of the inner wall of the reaction kettle body. Compared with the prior art, the medical material intermediate crushing device has the following beneficial effects that solid blocky medical material intermediates are conveyed into the feeding pipe through the discharging hopper, and the second motor is started to drive the stirring shaft and the crushing blades to rotate quickly, so that the solid blocky medical material intermediates can be crushed quickly; then diluent is sequentially conveyed into the conveying cavity and the diluting cavity through the water inlet pipe, liquid and powder in the diluting cavity can be rapidly mixed along with continuous rotation of the smashing blades, and the phenomenon that blocky or clustered medical material intermediates cannot be rapidly and evenly mixed with the liquid is avoided; and the medicine processing efficiency and the processing quality are effectively improved.

Description

Technical Field

[0001] This utility model relates to a purification device for medical material intermediates, belonging to the field of pharmaceutical synthesis and processing equipment. Background Technology

[0002] Medical material intermediates are chemical raw materials or products used in the process of drug synthesis. These chemical products do not require a drug production license and can be produced in ordinary chemical plants. As long as they meet certain standards, they can be used in drug synthesis. Solid pharmaceutical intermediates contain a large number of impurities and cannot be used directly in the production of drugs. They need to be purified.

[0003] In existing technologies, when purifying medical material intermediates in a reaction vessel, the raw materials are often in lumpy or clumpy form. The raw materials must be diluted and mixed into a liquid before purification can proceed. When lumpy or clumpy medical materials are directly added to the liquid, they cannot dissolve even with stirring, and the clumps will move with the stirring vortex, thus effectively reducing the efficiency and quality of pharmaceutical processing.

[0004] In summary, this invention provides a purification device for medical material intermediates to solve the above-mentioned problems. Utility Model Content

[0005] In view of the shortcomings of the existing technology, the purpose of this utility model is to provide a purification device for medical material intermediates, so as to solve the problem mentioned in the background art that the block raw materials cannot be quickly mixed with liquids.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a purification device for medical material intermediates, comprising a base frame, a reaction vessel body, and a stirrer. The reaction vessel body is fixedly connected to the top of the base frame. The stirrer extends through the bottom of the inner wall of the reaction vessel body. A load-bearing frustum extends through the top of the reaction vessel body and the top of the inner wall. A drug dilution assembly extends through the top and bottom of the load-bearing frustum. An external gear ring is fixedly fitted outside the load-bearing frustum and directly above the reaction vessel body. A housing is fixedly connected to one side of the top of the reaction vessel body. A first motor is fixedly connected inside the housing. A drive shaft is fixedly installed at the output end of the first motor. One end of the drive shaft extends through the housing and above the external gear ring. A drive wheel is fixedly fitted outside the drive shaft and above the external gear ring.

[0007] Furthermore, the drive wheel meshes with the external gear ring, the drive shaft is rotatably connected to the chassis, and the load-bearing frustum is rotatably connected to the reactor body.

[0008] Furthermore, a liquid inlet pipe is connected to the top of one side of the reactor body, and a liquid outlet pipe is connected to the bottom of one side of the reactor body.

[0009] Furthermore, the drug dilution assembly includes a transfer chamber that extends between the top and bottom of the load-bearing truncated cone. A dilution chamber is formed at the lower part of the transfer chamber, and an installation chamber is formed at the upper part of the transfer chamber. A second motor is installed inside the installation chamber, and a stirring shaft is fixedly connected to the output end of the second motor. One end of the stirring shaft penetrates the bottom of the inner wall of the installation chamber and the top of the inner wall of the dilution chamber and extends to the lower part of the dilution chamber. Three sets of pulverizing blades are evenly fixedly installed from top to bottom on the axial surface of the stirring shaft inside the dilution chamber. A conveying chamber is formed at the center of the top of the transfer chamber. A feed pipe is connected to one side of the transfer chamber above the load-bearing truncated cone, and a discharge hopper is connected to the top end of the feed pipe. A discharge pipe is connected to the bottom of the other side of the transfer chamber below the load-bearing truncated cone.

[0010] Furthermore, the delivery cavity is bent, and one end of the delivery cavity extends to one side of the top of the inner wall of the dilution cavity.

[0011] Furthermore, a water inlet pipe is rotatably connected to the top of the conveying chamber, and the conveying chamber is connected to the water inlet pipe.

[0012] The beneficial effects of this utility model are:

[0013] By feeding solid, blocky medical material intermediates into the feed pipe through a hopper, a second motor is started to drive the stirring shaft and pulverizing blades to rotate rapidly, thus quickly pulverizing the solid, blocky medical material intermediates. Then, the diluent is sequentially fed into the conveying chamber and the dilution chamber through the water inlet pipe. With the continuous rotation of the pulverizing blades, the liquid and powder in the dilution chamber are quickly mixed, avoiding the phenomenon that blocky or clumped medical material intermediates cannot be quickly mixed with the liquid, effectively improving the efficiency and quality of pharmaceutical processing.

[0014] The first motor is started, which sequentially drives the drive shaft, drive wheel, external gear ring, and load-bearing truss to rotate. The load-bearing truss drives the transfer chamber to rotate, which in turn drives the discharge pipe to rotate. The discharge pipe can rotate in a circular motion inside the reactor body. By opening the valve on the discharge pipe, the diluted solution can be evenly sprayed to various parts inside the reactor body. At the same time, the agitator is started to evenly stir the medical material intermediates inside the reactor body, reducing the stirring time required during the purification and refining process of medical material intermediates, thereby improving the purification and processing efficiency of medical material intermediates. Attached Figure Description

[0015] Other features, objects, and advantages of this invention will become more apparent from the following detailed description of non-limiting embodiments with reference to the accompanying drawings:

[0016] Figure 1 This is a perspective view of a purification device for a medical material intermediate according to the present invention;

[0017] Figure 2 This is a front view of a purification device for medical material intermediates according to the present invention;

[0018] Figure 3 This is a main cross-sectional view of a purification device for medical material intermediates according to the present invention;

[0019] Figure 4 for Figure 3 The main cross-sectional view of the drug dilution assembly shown.

[0020] In the diagram: 1. Base frame; 2. Reactor body; 3. Agitator; 4. Load-bearing frustum; 5. External gear ring; 6. Chassis; 7. First motor; 8. Drive shaft; 9. Drug dilution assembly; 10. Drive wheel; 11. Inlet pipe; 12. Drain pipe; 91. Transfer chamber; 92. Dilution chamber; 93. Mounting chamber; 94. Second motor; 95. Agitator shaft; 96. Crushing blade; 97. Conveying chamber; 98. Water inlet pipe; 99. Hopper; 910. Feed pipe; 911. Discharge pipe. Detailed Implementation

[0021] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0022] Please see Figure 1-4This utility model provides a technical solution: a purification device for medical material intermediates, including a base frame 1, a reaction vessel body 2, and a stirrer 3. The reaction vessel body 2 is fixedly connected to the top of the base frame 1. The stirrer 3 passes through the bottom of the inner wall of the reaction vessel body 2. A load-bearing frustum 4 passes through the top of the reaction vessel body 2 and the top of the inner wall. A drug dilution component 9 passes through the top and bottom of the load-bearing frustum 4. An external gear ring 5 is fixedly fitted outside the load-bearing frustum 4 and directly above the reaction vessel body 2. A housing 6 is fixedly connected to one side of the top of the reaction vessel body 2. A first motor 7 is fixedly connected inside the housing 6. The first motor 7 is connected to an external power source and is equipped with a power control switch. A drive shaft 8 is fixedly installed at the output end of the first motor 7. One end of the drive shaft 8 passes through the housing 6 and extends above the external gear ring 5. The top is fixedly fitted with a drive wheel 10. The mixer 3 plays an important role in the production process of medical material intermediates. It is mainly used for mixing, uniformly dispersing and reacting materials. The mixer 3 consists of an electric motor and a stirring frame. The electric motor drives the stirring frame to rotate, which can mix the medical material intermediates inside the reactor body 2. The drive wheel 10 meshes with the external gear ring 5. The drive shaft 8 is rotatably connected to the machine box 6. The load-bearing round platform 4 is rotatably connected to the reactor body 2. The top of one side of the reactor body 2 is connected to the liquid inlet pipe 11, and the bottom of one side of the reactor body 2 is connected to the liquid outlet pipe 12. Solenoid valves are installed on both the liquid inlet pipe 11 and the liquid outlet pipe 12, and power control switches are provided. By opening the valve on the liquid inlet pipe 11, the liquid medical material intermediate can be transported into the interior of the reactor body 2. By opening the valve on the liquid outlet pipe 12, the purified reagent can be discharged.

[0023] Please see Figure 2-4The drug dilution assembly 9 includes a transfer chamber 91, which extends between the top and bottom of the supporting truncated cone 4. A dilution chamber 92 is located at the lower part of the transfer chamber 91, and an installation chamber 93 is located at the upper part of the transfer chamber 91. A second motor 94 is installed inside the installation chamber 93. The second motor 94 is connected to an external power source and has a power control switch. A stirring shaft 95 is fixedly connected to the output end of the second motor 94. One end of the stirring shaft 95 passes through the bottom of the inner wall of the installation chamber 93 and the top of the inner wall of the dilution chamber 92, extending to the lower part of the dilution chamber 92. Three sets of pulverizing blades 96 are evenly fixedly installed from top to bottom on the axial surface of the stirring shaft 95, located inside the dilution chamber 92. A conveying chamber 97 is located at the center of the top of the transfer chamber 91. A feed pipe 910 is connected to one side of the transfer chamber 91 and above the load-bearing truncated cone 4. The top of the feed pipe 910 is connected to the discharge hopper 99. The bottom of the other side of the transfer chamber 91 and below the load-bearing truncated cone 4 is connected to the discharge pipe 911. A solenoid valve is installed on the discharge pipe 911, which is connected to an external power supply and is equipped with a power control switch. The conveying chamber 97 is bent. One end of the conveying chamber 97 extends to one side of the top of the inner wall of the dilution chamber 92. The top of the conveying chamber 97 is rotatably connected to the water inlet pipe 98. The core of the water inlet pipe 98 and the center of the load-bearing truncated cone 4 are located on the same longitudinal central axis, so that when the load-bearing truncated cone 4 rotates and drives the transfer chamber 91 to rotate, it does not affect the normal conveying between the top of the dilution chamber 92 and the water inlet pipe 98. The conveying chamber 97 is connected to the water inlet pipe 98.

[0024] Detailed implementation: By opening the liquid inlet pipe 11, the liquid medical material intermediate is transported into the interior of the reactor body 2. The solid block medical material intermediate is transported into the interior of the feed pipe 910 through the feed hopper 99. The second motor 94 is started to drive the stirring shaft 95 and the pulverizing blade 96 to rotate rapidly, thereby rapidly pulverizing the solid block medical material intermediate. Then, the diluent is transported into the conveying chamber 97 and the dilution chamber 92 through the water inlet pipe 98. With the continuous rotation of the pulverizing blade 96, the liquid and powder in the dilution chamber 92 can be quickly mixed, avoiding the phenomenon that the blocky or clumped medical material intermediate cannot be quickly mixed with the liquid, effectively improving the efficiency of pharmaceutical processing.

[0025] The first motor 7 is started, which sequentially drives the drive shaft 8, drive wheel 10, external gear ring 5 and load-bearing truncated cone 4 to rotate. The load-bearing truncated cone 4 drives the transfer chamber 91 to rotate, and the transfer chamber 91 drives the discharge pipe 911 to rotate. The discharge pipe 911 can move in a circular motion inside the reactor body 2. By opening the valve on the discharge pipe 911, the diluted liquid can be evenly sprayed to all parts inside the reactor body 2. At the same time, the agitator 3 is started to evenly stir and purify the medical material intermediate inside the reactor body 2. The purified medical material intermediate solution can be discharged by opening the drain pipe 12.

[0026] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A purification apparatus for a medical material intermediate, comprising a base frame, a reaction vessel body, and a stirrer, characterized in that: The reactor body is fixedly connected to the top of the base frame. The agitator passes through the bottom of the inner wall of the reactor body. A load-bearing frustum passes through the top of the reactor body and the top of the inner wall. A drug dilution assembly passes through the top and bottom of the load-bearing frustum. An external gear ring is fixedly fitted on the outside of the load-bearing frustum and directly above the reactor body. A housing is fixedly connected to one side of the top of the reactor body. A first motor is fixedly connected inside the housing. A drive shaft is fixedly installed at the output end of the first motor. One end of the drive shaft passes through the housing and extends above the external gear ring. A drive wheel is fixedly fitted on the outside of the drive shaft and at the top of the external gear ring.

2. The purification apparatus for a medical material intermediate according to claim 1, characterized in that: The drive wheel meshes with the external gear ring, the drive shaft is rotatably connected to the chassis, and the load-bearing frustum is rotatably connected to the reactor body.

3. The purification apparatus for a medical material intermediate according to claim 1, characterized in that: The top of one side of the reactor body is connected to an inlet pipe, and the bottom of one side of the reactor body is connected to a drain pipe.

4. The purification apparatus for a medical material intermediate according to claim 1, characterized in that: The drug dilution assembly includes a transfer chamber that extends between the top and bottom of a load-bearing truncated cone. A dilution chamber is located at the lower part of the transfer chamber, and an installation chamber is located at the upper part of the transfer chamber. A second motor is installed inside the installation chamber, and a stirring shaft is fixedly connected to the output end of the second motor. One end of the stirring shaft penetrates the bottom of the inner wall of the installation chamber and the top of the inner wall of the dilution chamber, extending to the lower part of the dilution chamber. Three sets of pulverizing blades are evenly fixedly installed from top to bottom on the axial surface of the stirring shaft inside the dilution chamber. A conveying chamber is located at the center of the top of the transfer chamber. A feed pipe is connected to one side of the transfer chamber above the load-bearing truncated cone, and a hopper is connected to the top of the feed pipe. A discharge pipe is connected to the bottom of the other side of the transfer chamber below the load-bearing truncated cone.

5. The purification apparatus for a medical material intermediate according to claim 4, characterized in that: The delivery chamber is bent, and one end of the delivery chamber extends to one side of the top of the inner wall of the dilution chamber.

6. The purification apparatus for a medical material intermediate according to claim 4, characterized in that: The top of the conveying chamber is rotatably connected to a water inlet pipe, and the conveying chamber is connected to the water inlet pipe.

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