Conical centrifugal tube
By designing a conical centrifuge tube with a movable moving part and a fixed rod structure, the problem of the missing conical bottom of the 2.0ml centrifuge tube was solved, achieving efficient RNA dissolution and a simplified operation process, improving experimental efficiency and sealing.
Patent Information
- Application Number
- CN202520527834.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-25
- Publication Date
- 2026-03-03
- Estimated Expiration
- 2035-03-25
AI Technical Summary
The existing 2.0ml centrifuge tubes lack a conical bottom design, which means that a small amount of nuclease-free water cannot completely cover the bottom, making RNA dissolution difficult. When aspirating the supernatant, the precipitate is easily disturbed, and the precipitate position needs to be manually marked, affecting experimental efficiency.
A conical centrifuge tube was designed, which enables rapid conversion between a conical bottom and a round bottom through a movable moving part and a fixed rod structure. Combined with a multi-seal design, it improves sealing performance and adaptability.
It improves the dissolution efficiency of trace precipitates, avoids precipitate disturbance, simplifies the operation process, and improves experimental extraction efficiency and sealing.
Smart Images

Figure CN223959679U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of metrological glass instruments, specifically a conical centrifuge tube. Background Technology
[0002] Conical centrifuge tubes, with a conical bottom, are the most commonly used type of centrifuge tube, effectively collecting precipitates during the extraction of substances such as proteins and nucleic acids. Cylindrical centrifuge tubes, with a narrower bottom and a wider top, are suitable for experiments requiring higher centrifugal forces. During centrifugation, samples tend to aggregate more tightly at the bottom, thus improving centrifugation efficiency.
[0003] In the purification of substances such as plasma RNA, the extraction system volume is often 1.5-2.0 ml (1.5 ml centrifuge tubes cannot be used), resulting in very little precipitate. However, since existing 2.0 ml centrifuge tubes lack the conical bottom of 1.5 ml tubes, the precipitate is easily disturbed during supernatant aspiration, and its location needs to be marked with a marker during the drying process. Furthermore, the final addition of nuclease-free water for dissolving RNA is only 25 μl or even less than 20 μl, which is a very small amount. This tiny amount of nuclease-free water cannot completely cover the bottom of the 2.0 ml centrifuge tube (occupying only about 1 / 5 of the bottom), making RNA dissolution difficult. Utility Model Content
[0004] This invention provides a conical centrifuge tube, which solves the problems mentioned in the background art where the 2.0ml centrifuge tube does not have a conical bottom like the 1.5ml centrifuge tube, and the trace amount of nuclease-free water cannot completely cover the bottom of the 2.0ml centrifuge tube, resulting in difficulty in RNA dissolution, easy disturbance of the precipitate during the aspiration of the supernatant, and the need to mark the precipitate position with a marker during the precipitate drying process.
[0005] This utility model provides the following technical solution: a conical centrifuge tube, including a centrifuge tube body, a cap provided at the top of the centrifuge tube body, the centrifuge tube body including a straight cylindrical part, a round bottom and a conical bottom, the round bottom being located between the straight cylindrical part and the conical bottom, a through hole being provided in the middle of the round bottom, a movable part being movably connected in the inner cavity of the through hole, the inner wall of the movable part forming a semi-circular structure with the inner wall of the round bottom, the outer wall of the movable part being adapted to the inner wall of the conical bottom, and the movable part being connected to the conical bottom through a fixing rod.
[0006] Preferably, a threaded groove is provided on one side of the bottom of the cone, the bottom end of the fixing rod is threadedly connected to the inner cavity of the threaded groove, the fixing rod is movably connected to the moving part, and a sealing ring is provided between the fixing rod and the moving part.
[0007] Preferably, a fixing ring is fixedly connected to the outer ring at the top of the centrifuge tube. The fixing ring has a convex structure, the vertical part of the fixing ring is threaded to the tube cap, and a sealing plate is fixedly connected to the top of the horizontal part of the fixing ring.
[0008] Preferably, a cap core is movably connected to the middle of the inner cavity of the cap, the cap core is adapted to the inner cavity of the straight section, and the cap core is provided with a through hole, which is adapted to the fixing rod.
[0009] Preferably, the distance between the bottom of the cap core and the top of the inner cavity of the tube cap is the same as the height of the vertical part of the fixing ring.
[0010] Preferably, the outer surface of the movable part is covered with a sealing gasket.
[0011] Compared with the prior art, the present invention has the following beneficial effects:
[0012] 1. When the conical centrifuge tube is 2.0ml, it has a conical bottom similar to that of a 1.5ml centrifuge tube, which can improve the dissolution efficiency of trace precipitates. During the process of discarding the supernatant, the precipitate is not easily disturbed. In addition, the nuclease-free water can cover the bottom of the centrifuge tube, so there is no need to mark the position of the precipitate, and there is no need to transfer the precipitate to a 1.5ml centrifuge tube in the subsequent purification process, thus improving the experimental extraction efficiency.
[0013] 2. The conical centrifuge tube, through the setting of a fixed rod and a movable part, allows the position of the movable part to be changed by turning the fixed rod, so that the centrifuge tube can quickly rotate between round-bottom centrifuge tubes and conical-bottom centrifuge tubes, thereby improving the adaptability of the centrifuge tube.
[0014] 3. The conical centrifuge tube, through the connection method of the tube cap and the centrifuge tube body, has multiple seals between the tube cap and the centrifuge tube body, which improves the sealing performance of the centrifuge tube and facilitates its use. Attached Figure Description
[0015] Figure 1 This is a front view of the structure of this utility model;
[0016] Figure 2 This is an exploded view of the structure of this utility model;
[0017] Figure 3 The structure of this utility model Figure 2 Diagram showing the view from below;
[0018] Figure 4 This is a schematic diagram showing the top of the movable part of the structure of this utility model being flush with the top of the through hole;
[0019] Figure 5 This is a schematic diagram showing the moving part of the structure of this utility model fitting against the inner wall of the cone bottom.
[0020] In the diagram: 1. Centrifuge tube body; 2. Tube cap; 3. Cap core; 4. Through hole; 5. Fixing ring; 6. Fixing rod; 7. Straight cylinder section; 8. Round bottom; 9. Conical bottom; 10. Moving part; 11. Threaded groove; 12. Through hole. Detailed Implementation
[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0022] This utility model provides a conical centrifuge tube, including a centrifuge tube body 1. The centrifuge tube body 1 includes a straight cylindrical part 7, a round bottom 8, and a conical bottom 9. The round bottom 8 is located between the straight cylindrical part 7 and the conical bottom 9. A through hole 12 is provided in the middle of the round bottom 8. A movable part 10 is movably connected inside the cavity of the through hole 12. The movable part 10 has a conical structure. The outer wall of the movable part 10 is adapted to the inner wall of the conical bottom 9. The inner wall of the movable part 10 has an arc-shaped structure. When the top of the movable part 10 is flush with the top of the through hole 12, the inner wall of the movable part 10 and the inner wall of the round bottom 8 form a semi-circular structure. At this time, the bottom of the conical centrifuge tube is round. When the outer wall of the movable part 10 is tightly fitted with the inner wall of the conical bottom 9, the inner wall of the movable part 10 and the inner wall of the round bottom 8 can form a conical bottom. The centrifuge tube can quickly switch between a round bottom and a conical bottom, so that the centrifuge tube can meet a variety of needs and improve the adaptability of the centrifuge tube.
[0023] The outer surface of the moving part 10 is covered with a sealing gasket, which is made of a flexible material, such as silicone, to improve the sealing performance of the centrifuge tube.
[0024] The movable part 10 is connected to the cone bottom 9 via the fixed rod 6. A threaded groove 11 is provided on one side of the cone bottom 9. The bottom end of the fixed rod 6 is threadedly connected to the inner cavity of the threaded groove 11. The fixed rod 6 is movably connected to the movable part 10. A sealing ring is provided between the fixed rod 6 and the movable part 10. The sealing ring is made of a flexible material, such as silicone. The top end of the fixed rod 6 is located outside the centrifuge tube 1, making it easy for the user to screw the fixed rod 6.
[0025] A cap 2 is provided at the top of the centrifuge tube 1. A retaining ring 5 is fixedly connected to the outer ring of the top of the centrifuge tube 1. The retaining ring 5 has a convex structure. The vertical part of the retaining ring 5 is threadedly connected to the cap 2. A sealing plate is fixedly connected to the top of the horizontal part of the retaining ring 5. The sealing plate is made of flexible material, such as silicone.
[0026] A cap core 3 is movably connected to the middle of the inner cavity of the cap 2. The cap core 3 is adapted to the inner cavity of the straight section 7. The cap core 3 is provided with a through hole 4, which is adapted to the fixing rod 6. The distance between the bottom of the cap core 3 and the top of the inner cavity of the cap 2 is the same as the height of the vertical part of the fixing ring 5.
[0027] As described above, when the cap 2 is threadedly connected to the centrifuge tube 1, the top of the centrifuge tube 1 is tightly fitted with the top of the inner cavity of the cap 2, the bottom of the cap 2 is tightly fitted with the horizontal end of the fixing ring 5, and the cap core 3 is tightly fitted with the inner wall of the straight cylinder 7. The centrifuge tube 1 and the cap 2 are sealed by multiple layers, which improves the sealing performance of the conical centrifuge tube and facilitates its use.
[0028] In summary: When using this conical centrifuge tube, the user can change the position of the moving part 10 by screwing on the fixing rod 6. When the fixing rod 6 is threadedly connected to the top of the threaded groove 11, the top of the moving part 10 is at the same height as the top of the through hole 12, and the inner wall of the moving part 10 and the inner wall of the round bottom 8 form a semi-circular structure. At this time, the bottom of the centrifuge tube is round. When the bottom of the fixing rod 6 is tightly fitted to the bottom of the threaded groove 11, the top of the moving part 10 and the bottom of the through hole 12 are at the same height, and the moving part 10 is tightly fitted to the inner wall of the conical bottom 9. The inner wall of the moving part 10 and the inner wall of the round bottom 8 form a conical bottom, thereby enabling the centrifuge tube to be quickly converted between a round bottom centrifuge tube and a conical bottom centrifuge tube, improving the applicability of the centrifuge tube.
[0029] When the conical centrifuge tube is a 2.0ml centrifuge tube and is used for the purification of substances such as plasma and RNA, the user tightly fits the moving part 10 against the inner wall of the conical part 9, converting the centrifuge tube into a conical-bottom centrifuge tube. This improves the dissolution efficiency of trace precipitates, makes it less likely to disturb the precipitate during the discarding of supernatant, and allows the nuclease-free water to cover the bottom of the centrifuge tube. There is no need to mark the precipitate position, nor is it necessary to transfer the precipitate to a 1.5ml centrifuge tube during subsequent purification, thus improving the experimental extraction efficiency.
[0030] All standard parts used in this utility model can be purchased from the market, and irregularly shaped parts can be customized according to the description and drawings. The specific connection methods of each part all adopt conventional means such as bolts that are mature in the prior art. The machinery, parts and equipment all adopt conventional models in the prior art, which will not be described in detail here. The contents not described in detail in this specification belong to the prior art known to those skilled in the art. Although the embodiments of this utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this utility model. The scope of this utility model is defined by the appended claims and their equivalents.
Claims
1. A conical centrifuge tube, comprising a centrifuge tube body (1), characterized in that: The centrifuge tube (1) is provided with a cap (2) at the top. The centrifuge tube (1) includes a straight cylindrical part (7), a round bottom (8) and a conical bottom (9). The round bottom (8) is located between the straight cylindrical part (7) and the conical bottom (9). The center of the round bottom (8) is provided with a through hole (12). A movable part (10) is movably connected in the inner cavity of the through hole (12). The inner wall of the movable part (10) and the inner wall of the round bottom (8) form a semi-circular structure. The outer wall of the movable part (10) is adapted to the inner wall of the conical bottom (9). The movable part (10) is connected to the conical bottom (9) through a fixing rod (6).
2. A conical centrifuge tube according to claim 1, characterized in that: A threaded groove (11) is provided on one side of the bottom (9) of the cone. The bottom end of the fixing rod (6) is threadedly connected to the inner cavity of the threaded groove (11). The fixing rod (6) is movably connected to the moving part (10), and a sealing ring is provided between the fixing rod (6) and the moving part (10).
3. A conical centrifuge tube according to claim 1, characterized in that: A fixing ring (5) is fixedly connected to the outer ring at the top of the centrifuge tube (1). The fixing ring (5) has a convex structure. The vertical part of the fixing ring (5) is threadedly connected to the tube cap (2). A sealing plate is fixedly connected to the top of the horizontal part of the fixing ring (5).
4. A conical centrifuge tube according to claim 3, characterized in that: The cap (2) has a cap core (3) movably connected to the middle of its inner cavity. The cap core (3) is adapted to the inner cavity of the straight cylinder (7). The cap core (3) has a through hole (4) adapted to the fixing rod (6).
5. A conical centrifuge tube according to claim 4, characterized in that: The distance between the bottom of the cap core (3) and the top of the inner cavity of the tube cap (2) is the same as the height of the vertical part of the fixing ring (5).
6. A conical centrifuge tube according to claim 1, characterized in that: The outer surface of the moving part (10) is covered with a sealing gasket.