Slide cleaning device adaptive to intraoperative rapid freezing immunohistochemical staining equipment

Abstract

The slide cleaning device comprises a supporting module, a movable sliding rail module and a cleaning liquid path module, the movable sliding rail module comprises a driving device, a belt wheel driven device and a guide rail sliding device, the driving device and the guide rail sliding device are both fixedly arranged on the supporting module, the belt wheel driven device is arranged on the supporting module, and the belt wheel driven device is arranged on the belt wheel driven device. One end of the belt wheel driven device is fixedly connected with the driving device, the other end of the belt wheel driven device is fixed to the supporting module, and the belt wheel driven device is connected with the guide rail sliding device through a synchronous belt and connected with the cleaning fluid path module through a pipeline. The device can be freely moved to a corresponding position according to the process requirement, and the reaction residual reagent on the glass slide is washed and blow-dried, so that the next operation can be carried out.

Description

Technical Field

[0001] This utility model belongs to the technical field of intraoperative rapid frozen immunohistochemical staining equipment, and specifically relates to a slide cleaning device adapted to intraoperative rapid frozen immunohistochemical staining equipment. Background Technology

[0002] Automated immunohistochemical staining equipment automates the immunohistochemical process. This means that computer software controls the automatic sample loading, cleaning, heating and incubation, and staining operations, simulating manual immunohistochemical procedures to achieve full automation of the immunohistochemical staining process. In automated immunohistochemical staining equipment, the cleaning system is particularly important. Each addition of different reagents requires cleaning the slides; cleaning is an integral part of the entire immunohistochemical staining process, and the performance of the cleaning system has a significant impact on the final staining quality.

[0003] Current domestic research on immunohistochemical staining equipment mainly focuses on postoperative immunohistochemical pathological diagnosis, which does not have high requirements for the timeliness of immunohistochemistry or the effectiveness of slide cleaning and drying in each step. The intraoperative frozen immunohistochemistry machine adapted to this system is quite different from the postoperative immunohistochemistry equipment, and it has higher requirements for timeliness, washing effect, and drying effect. Utility Model Content

[0004] In order to solve the above-mentioned problems in the prior art, this application provides a slide cleaning device adapted to intraoperative rapid frozen immunohistochemical staining equipment to solve the above-mentioned technical defects.

[0005] According to a first aspect of this utility model, a slide cleaning device adapted to intraoperative rapid frozen immunohistochemical staining equipment is proposed, comprising: a support module, a movable slide rail module, and a cleaning fluid path module. The support module includes a guide rail mounting base plate, and the movable slide rail module includes a drive device, a pulley driven device, and a guide rail sliding device. The drive device and the guide rail sliding device are both fixedly mounted on the guide rail mounting base plate. One end of the pulley driven device is fixed to the drive device by screws, and the other end is fixed to the guide rail mounting base plate. The pulley driven device includes a synchronous belt, and the guide rail sliding device is connected to the synchronous belt. The pulley driven device and the cleaning fluid path module are connected through a pipe. With this structural configuration, when the drive device is started, the synchronous belt on the pulley driven device rotates, driving the guide rail sliding device to run, thereby enabling slide rinsing, slide cleaning, and other actions.

[0006] In some specific embodiments, the driving device includes a motor, and the pulley driven device includes a drive pulley, which is fixed to the output shaft of the motor by screws. With this structure, when the motor starts, the drive pulley rotates following the motor.

[0007] In some specific embodiments, the pulley driven device further includes a driven pulley and an adjusting seat. The driven pulley is mounted on a fixed shaft, and the adjusting seat is fixedly mounted on a guide rail mounting base plate. The adjusting seat has an adjusting hole or adjusting groove, and the fixed shaft is disposed within the adjusting hole or adjusting groove and can move along the adjusting hole or adjusting groove. The synchronous belt is mounted on the drive pulley and the driven pulley. With this structural arrangement, the driven pulley can rotate around the fixed shaft on the adjusting seat following the drive pulley. The adjusting seat has an adjusting hole or adjusting groove, which allows the driven pulley and the fixed shaft to move along the direction of the adjusting hole or adjusting groove. This facilitates fine-tuning to ensure that the synchronous belt is correctly aligned with the drive pulley and the driven pulley, reducing wear and improving the stability and lifespan of the device.

[0008] In some specific embodiments, the guide rail sliding device includes a guide rail mounting block, and a limiting groove is provided on the guide rail mounting base plate. The guide rail mounting block is mounted on the guide rail mounting base plate through the limiting groove. This structural design increases the connection strength and stability between the guide rail mounting block and the guide rail mounting base plate, preventing the guide rail mounting block from loosening or shifting during use, thereby ensuring the reliability of the entire system and guaranteeing the straightness of the guide rail mounting block during installation.

[0009] In some specific embodiments, the guide rail sliding device further includes a guide rail, and the guide rail mounting block is provided with a limiting groove. The guide rail is mounted on the guide rail mounting block through the limiting groove. This structural design increases the connection strength and stability between the guide rail and the guide rail mounting block, preventing the guide rail from loosening or shifting during use, while also ensuring the straightness of the guide rail installation.

[0010] In some specific embodiments, the guide rail sliding device further includes a timing belt pressure plate, which is disposed on the guide rail and connected to the timing belt. This structure allows the timing belt pressure plate to move on the guide rail when the timing belt moves.

[0011] In some specific embodiments, the guide rail sliding device further includes a nozzle, which is fixedly mounted on the timing belt pressure plate. This configuration allows the nozzle to move along with the timing belt pressure plate as it moves on the guide rail.

[0012] In some specific embodiments, the nozzle has both liquid orifices and air orifices, each containing a cavity. The liquid orifice is at an inclined angle, while the air orifice is flared and flat. Through this structural design, the liquid orifice of the nozzle can achieve liquid diversion and pressurization for full-coverage rinsing of the glass slide, while the air orifice can achieve depressurization and acceleration of the flowing gas for rapid and uniform drying of the glass slide.

[0013] In some specific embodiments, the reagent addition system, slide rinsing system, slide blowing system, steel needle internal and external washing system, and waste liquid discharge system are sequentially connected via pipelines in the cleaning fluid circuit module. This structural arrangement allows for the sequential execution of a series of actions, including reagent addition, slide rinsing, slide blowing, steel needle internal and external washing, and waste liquid discharge.

[0014] In some specific embodiments, the cleaning fluid circuit module and the nozzle in the moving slide rail module are connected by pipes. This structural arrangement enables integrated operation of the entire device. The cleaning fluid circuit module can precisely control the supply of liquid or gas as needed, while the nozzle is responsible for the specific application of the work, such as rinsing and drying.

[0015] Compared with the prior art, the beneficial results of this utility model are as follows:

[0016] I. This device can achieve highly efficient slide rinsing and cleaning operations. Compared with conventional slide cleaning devices on the market, it has outstanding advantages in high cleaning efficiency, good rinsing effect, and excellent cleaning effect. Its cleaning mechanism is extremely suitable for cryoimmunohistochemistry equipment that requires rapid results.

[0017] Second, the nozzle of this device is movable, and only one circuit is needed to realize multi-channel glass slide cleaning and blowing operations, which has lower cost and smaller overall size.

[0018] Third, the device is highly independent, with each liquid path process being independent and having little overlap. When performing the slide washing process, it does not interfere with other immunohistochemical processes, which can minimize the overall process time. In addition, the independent device has wide adaptability and can be easily matched with multiple models of complete machines. Attached Figure Description

[0019] The accompanying drawings are included to provide a further understanding of the embodiments and are incorporated in and constitute a part of this specification. The drawings illustrate embodiments and, together with the description, serve to explain the principles of the present invention. Other embodiments and many anticipated advantages of the embodiments will be readily recognized as they become better understood through reference to the following detailed description. Elements in the drawings are not necessarily to scale. The same reference numerals refer to corresponding similar parts.

[0020] Figure 1 This is a schematic diagram of a slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to the first embodiment of the present invention.

[0021] Figure 2 This is an exploded view of the support module and the movable slide rail module according to the first embodiment of this utility model;

[0022] Figure 3 This is an exploded view of the cleaning fluid circuit module according to the first embodiment of this utility model;

[0023] Figure 4 This is a schematic diagram of the nozzle structure according to the first embodiment of the present invention;

[0024] Figure 5 This is a schematic cross-sectional view of the nozzle according to the first embodiment of the present invention.

[0025] The meanings of the numbers in the diagram are as follows: 01-Support module, 02-Moving slide rail module, 03-Cleaning fluid circuit module, 04-Gantry left support plate, 05-Gantry support, 06-Gantry right support plate, 07-Connecting support, 08-Guide rail mounting base plate, 9-Pipeline support plate, 10-Sheet metal support seat, 11-Synchronous belt, 12-Adjusting seat, 13-Driven pulley, 14-Fixed shaft, 15-Guide rail, 16-Guide rail mounting block, 17-Adapter plate, 18-Gland cover, 19-Covering sheet metal, 20-Optical coupler sheet metal, 21-Adjustable front adapter plate, 22-Synchronous belt pressure... 23-Optical coupler, 24-Drive pulley, 25-Nozzle, 26-Motor mounting base, 27-Motor, 28-Pump mounting plate, 29-Pump mounting plate support, 30-Washing station pump, 31-Cleaning pump, 32-Air pump, 33-Internal washing pump, 34-External washing pump, 35-Washing station, 36-Plunger pump, 37-Valve assembly, 38-Valve assembly mounting plate, 39-Pipeline, 40-Steel needle, 41-Splashproof cover plate, 42-Splashproof cover plate support, 43-Air valve mounting sheet metal, 44-Air valve, 45-Waste liquid pump, 46-Pipeline limit block, 47-Air hole, 48-Liquid hole. Detailed Implementation

[0026] In the following detailed description, reference is made to the accompanying drawings, which form part of the detailed description and illustrate illustrative specific embodiments in which the present invention may be practiced. In this regard, directional terms such as “top,” “bottom,” “left,” “right,” “up,” “down,” etc., are used with reference to the orientation of the described figures. Because components of the embodiments can be positioned in several different orientations, directional terms are used for illustrative purposes and are by no means limiting. It should be understood that other embodiments may be utilized or logical changes may be made without departing from the scope of the present invention. Therefore, the following detailed description should not be taken in a limiting sense, and the scope of the present invention is defined by the appended claims.

[0027] This invention proposes an electrically controlled liquid extraction device. Figure 1 A schematic diagram of the slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining device according to the first embodiment of this utility model is shown, as follows: Figure 1As shown, a slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment includes: a support module 01, a movable slide rail module 02, and a cleaning fluid path module 03. The movable slide rail module 02 is fixedly mounted on the support module 01, and the cleaning fluid path module 03 is connected to the movable slide rail module 02 through a pipe.

[0028] Figure 2 An exploded view of the support module and the movable slide rail module of the first embodiment of this utility model is shown. Figure 2 As shown, the support module 01 includes a left gantry support plate 04, a gantry support 05, a right gantry support plate 06, a connecting support 07, and a guide rail mounting base plate 08. The left gantry support plate 04 and the right gantry support plate 06 are located on either side of the guide rail mounting base plate 08. The connecting support 07 is L-shaped, and the guide rail mounting base plate 08 is fixedly connected to the left gantry support plate 04 and the right gantry support plate 06 respectively via bolts. The gantry support 05 is also L-shaped and is also fixedly installed on the inner side of the left gantry support plate 04 and the right gantry support plate 06 respectively via bolts. This bolted connection ensures structural stability and facilitates equipment assembly and maintenance.

[0029] In specific embodiments, welding can also be used to directly weld the connecting support 07 to the left support plate 04 and the right support plate 06 of the gantry. Then, the connecting support 07 is welded to the guide rail mounting base plate 08, thus fixing the guide rail mounting base plate 08 to the left support plate 04 and the right support plate 06 of the gantry. Alternatively, welding can be used to fix the gantry support 05 to the inner side of the left support plate 04 and the right support plate 06 of the gantry. Fixing the connection by welding provides the structure with higher strength and rigidity.

[0030] Continue as Figure 2 As shown, the movable slide rail module 02 includes a motor 27, a motor mounting base 26, a drive pulley 24, a synchronous belt 11, a driven pulley 13, a fixed shaft 14, an adjusting seat 12, a guide rail 15, a guide rail mounting block 16, a synchronous belt pressure plate 22, an adapter plate 17, an adjustable front adapter plate 21, a pressure cover 18, a nozzle 25, a pipe support plate 9, an optocoupler 23, an optocoupler sheet metal 20, a splash guard 41, a cover / shield sheet metal 19, a sheet metal support seat 10, a splash guard 42, and a nozzle / pipe limiting block 46. The motor 27 is fixedly mounted on the motor mounting base 26, which is fixedly mounted on the guide rail mounting base plate 08. The motor 27 serves as the drive device, providing power to the entire movable slide rail module.

[0031] The drive pulley 24 is fixed to the output shaft of the motor 27 by fastening screws and can rotate with the motor 27. The driven pulley 13 is mounted on the fixed shaft 14 and can rotate around the fixed shaft 14. The adjusting seat 12 is fixedly mounted on the guide rail mounting base plate 08, and the adjusting seat 12 is provided with adjusting holes or adjusting grooves. The fixed shaft 14 is set in the adjusting holes or adjusting grooves, so that the driven pulley 13 and the fixed shaft 14 can move along the direction of the adjusting holes or adjusting grooves. This allows for convenient fine-tuning to ensure that the synchronous belt 11 is correctly aligned with the drive pulley 24 and the driven pulley 13, reducing wear and improving the stability and lifespan of the device. The synchronous belt 11 is mounted on the drive pulley 24 and the driven pulley 13.

[0032] The guide rail mounting block 16 is mounted on the guide rail mounting base plate 08. A limit groove is provided on the guide rail mounting base plate 08 to ensure the straightness of the guide rail mounting block 16 during installation. The guide rail 15 is mounted on the guide rail mounting block 16, and a limit groove is provided on the guide rail mounting block 16 to ensure the straightness of the guide rail 15 during installation. The synchronous belt pressure plate 22 is connected to the synchronous belt 11, the guide rail 15's matching slider, and the adapter plate 17. The optocoupler sheet metal 20 is mounted on the adjustable front adapter plate 21. When the motor 27 starts, the drive pulley 24 rotates with the motor 27. The synchronous belt 11 and the driven pulley 13 move accordingly under the action of the drive pulley 24. When the synchronous belt 11 moves, it can drive the synchronous belt pressure plate 22, the guide rail 15's matching slider, the adapter plate 17, the adjustable front adapter plate 21, and the optocoupler sheet metal 20 mounted on them to move on the guide rail 15.

[0033] In a specific embodiment, the adapter plate 17 has a pipe groove and a fixing hole. The pressure cap 18 mates with the pipe groove on the adapter plate 17 to limit the movement of the pipe passing through the adapter plate 17. The adjustable front adapter plate 21 is connected to the adapter plate 17 and has adjustment holes for vertical adjustment. The nozzle 25 is fixed on the adjustable front adapter plate 21. The optocoupler 23 is mounted on the guide rail mounting block 16 for zeroing operation of the motor 27.

[0034] In a specific embodiment, the covering sheet metal 19 is fixed to the support module 01 via the sheet metal support base 10, which limits the movement of the sliding rail module 02 pipeline and also shields the sliding rail module 02. The pipeline support plate 09 is fixed to the guide rail 15, which guides the movement of the pipeline. The nozzle pipeline limiting block 46 is fixed to the guide rail mounting base plate 08. When the nozzle 25 moves under the drive of the motor 24, the pipeline 39 mounted on the nozzle 25 moves within a certain free range under the limiting effect of the covering sheet metal 19 and the pressure cap 18, and under the guidance of the pipeline support plate 09 and the nozzle pipeline limiting block 46. This prevents the pipeline 39 from moving randomly or even getting stuck. The anti-splash cover plate 41 is connected to the frame via the anti-splash cover plate support 42 to prevent splash contamination.

[0035] In a specific embodiment, when the control unit issues a command, the motor 27 runs the corresponding number of steps. At the same time, the drive pulley 24 rotates under the drive of the motor 27. The synchronous belt 11 moves under the action of the drive pulley 24 and the driven pulley 13. The synchronous belt 11 drives the synchronous belt pressure plate 22, the guide rail 15 with matching slider, the adapter plate 17, the adjustable front adapter plate 21 and the nozzle 25 installed on it to move on the guide rail 15 to the position issued by the control unit. Then, according to the command of the control unit, the slide rinsing liquid path of the cleaning liquid path module 03 or the slide blowing system starts to work.

[0036] Figure 3 An exploded view of the cleaning fluid circuit module according to the first embodiment of this utility model is shown. Figure 3 As shown, the cleaning fluid circuit module 03 includes a pump mounting plate 28, a pump mounting plate support 29, a washing station pump 30, a cleaning pump 31, an air pump 32, an internal washing pump 33, an external washing pump 34, a washing station 35, a plunger pump 36, a valve group 37, a valve group mounting plate 38, a pipe 39, a steel needle 40, a splash guard 41, a splash guard support 42, an air valve mounting sheet metal 43, an air valve 44, and a waste liquid pump 45. The pump mounting plate support 29 is fixedly installed on both sides of the bottom of the pump mounting plate 28, and the pump mounting plate support 29 is installed on the frame. The washing station pump 30, cleaning pump 31, air pump 32, internal washing pump 33, and external washing pump 34 are installed on the pump mounting plate 28 in sequence. The plunger pump 36 is installed on both sides of the frame. The valve group 37 is installed on the valve group mounting plate 38, which is fixed on the frame. The pipeline 39 is connected to the washing station pump 30, cleaning pump 31, air pump 32, internal washing pump 33, external washing pump 34, washing station 35, plunger pump 36, valve group 37, and nozzle 25 according to the requirements of the liquid circuit system. In the cleaning liquid circuit module 03, the pumps and valves are controlled by the control unit, which controls the on / off of the corresponding pumps and valves according to their specific functions.

[0037] In a specific embodiment, the cleaning fluid circuit module 03 can be divided into a reagent addition system, a slide rinsing system, a slide blowing system, a steel needle internal and external washing system, and a waste liquid discharge system according to its functions. The reagent addition system includes a steel needle 40, a pipe 39, a cleaning pump 31, a plunger pump 36, and a valve group 37. When the control unit issues a reagent addition command, the corresponding solenoid valve in the valve group 37 opens, and the cleaning fluid is drawn into the cleaning pump 31 and the plunger pump 36 by the steel needle 40.

[0038] In a specific embodiment, the slide rinsing system includes a cleaning pump 31, a valve group 37, a pipe 39, and a nozzle 25. When the nozzle 25 moves to the permissible position under the drive of the motor 27, and the control unit issues a slide rinsing command, the cleaning pump 31 starts pumping liquid, and the corresponding solenoid valve in the valve group 37 opens. At this time, the cleaning liquid is pumped out through the nozzle 25 at a certain angle with a certain flow rate and pressure.

[0039] In a specific embodiment, the slide cleaning system includes an air pump 32, an air valve 44, a pipe 39, and a nozzle 25. When the nozzle 25 moves to the allowable position under the drive of the motor 27, the control unit issues a slide cleaning command, the air pump 32 starts, and the air valve 44 opens. At this time, the high-pressure gas output by the air pump 32 is pumped out through the nozzle 25 at a certain angle with a certain flow rate and pressure.

[0040] In a specific embodiment, the steel needle internal and external washing system includes an internal washing pump 33, an external washing pump 34, a washing station 35, a plunger pump 36, a valve group 37, a pipeline 39, and steel needles 40. When the control unit issues an internal and external washing command, the left and right steel needles 40 move to the corresponding washing station 35 positions. At this time, the plunger pump 36 moves to the zero position, the internal washing pump 33 and the external washing pump 34 are turned on, pumping liquid at a certain pressure and flow rate. The valve group 37 opens the corresponding valve, and the liquid flows into the washing station 35 and the steel needles 40 to perform internal and external washing.

[0041] In a specific embodiment, the waste liquid discharge system includes a washing station pump 30, a pipeline 39, and a waste liquid pump 45. When the control unit issues a waste liquid pumping command, the waste liquid pump 45 and the washing station pump 30 start up, and the waste liquid temporarily stored in the waste liquid tank is pumped into the waste liquid storage unit.

[0042] Figure 4 and Figure 5 A schematic diagram and a cross-sectional view of the nozzle are shown. Figure 4 (a) and Figure 4 (b) Schematic diagrams showing different nozzle angles, such as Figure 4 (a) and Figure 4 As shown in (b), the nozzle 25 has liquid holes 48 at an inclined angle, which can achieve liquid diversion and pressurization to fully cover and rinse the glass slide. The nozzle 25 also has air holes 47, which can reduce the pressure and increase the speed of the flowing gas to quickly and evenly dry the glass slide. Figure 5 (a) is a cross-sectional view of the nozzle perpendicular to the liquid orifice 48, showing the cavity structure inside the liquid orifice 48, as shown in the diagram. Figure 5 As shown in (a), the upper end of the liquid hole 48 is provided with a threaded connector for fixing the nozzle, and the liquid hole 48 has a cuboid-shaped cavity inside it. Figure 5 (b) is a cross-sectional schematic diagram of the nozzle perpendicular to the air hole 47, showing the cavity structure inside the air hole 47, such as... Figure 5 (b) The upper end of the air hole 47 is also provided with a threaded connector for fixing the nozzle. The air hole 47 is flared and flat. The cross-sectional shape of the cavity inside the air hole 47 is similar to a "clothes hanger". The lower end of the cavity is also provided with two exhaust ports, from which the gas flows out. Figure 5 (c) is a cross-sectional view of the nozzle perpendicular to both the liquid hole 48 and the air hole 47, showing the side structure of the liquid hole 48 and the air hole 47, as well as the specific tilt angle of the liquid hole 48.

[0043] It is obvious that those skilled in the art can make various modifications and changes to the embodiments of this utility model without departing from the spirit and scope of this utility model. In this way, this utility model is also intended to cover such modifications and changes if they fall within the scope of the claims of this utility model and their equivalents. The word "comprising" does not exclude the presence of other elements or steps not listed in the claims. The simple fact that certain measures are described in mutually different dependent claims does not indicate that a combination of these measures cannot be used for profit. Any reference numerals in the claims should not be considered as limiting the scope.

Claims

1. A slide cleaning device adapted for intraoperative rapid frozen immunohistochemical staining equipment, characterized in that, include: The system comprises a support module, a movable slide rail module, and a cleaning fluid circuit module. The support module includes a guide rail mounting base plate. The movable slide rail module includes a drive device, a pulley driven device, and a guide rail sliding device. The drive device and the guide rail sliding device are both fixedly mounted on the guide rail mounting base plate. One end of the pulley driven device is fixedly connected to the drive device, and the other end is fixed to the guide rail mounting base plate. The pulley driven device includes a timing belt, and the guide rail sliding device is connected to the timing belt. The pulley driven device and the cleaning fluid circuit module are connected via pipes.

2. The slide cleaning device adapted to intraoperative rapid frozen immunohistochemical staining equipment according to claim 1, characterized in that, The driving device includes a motor, and the pulley driven device includes a drive pulley, which is fixed to the output shaft of the motor by screws.

3. A slide cleaning device adapted to intraoperative rapid frozen immunohistochemical staining equipment according to claim 2, characterized in that, The pulley driven device further includes a driven pulley and an adjusting seat. The driven pulley is mounted on a fixed shaft, and the adjusting seat is fixedly mounted on the guide rail mounting base plate. The adjusting seat is provided with an adjusting hole, and the fixed shaft is disposed in the adjusting hole. The synchronous belt is mounted on the drive pulley and the driven pulley.

4. A slide cleaning device adapted to intraoperative rapid frozen immunohistochemical staining equipment according to claim 1, characterized in that, The guide rail sliding device includes a guide rail mounting block, and a limiting groove is provided on the guide rail mounting base plate. The guide rail mounting block is mounted on the guide rail mounting base plate through the limiting groove.

5. A slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to claim 4, characterized in that, The guide rail sliding device also includes a guide rail, and the guide rail mounting block is provided with a limiting groove, through which the guide rail is mounted on the guide rail mounting block.

6. A slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to claim 5, characterized in that, The guide rail sliding device also includes a timing belt pressure plate, which is disposed on the guide rail and connected to the timing belt.

7. A slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to claim 6, characterized in that, The guide rail sliding device also includes a nozzle, which is fixedly mounted on the synchronous belt pressure plate.

8. A slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to claim 7, characterized in that, The nozzle has both a liquid hole and an air hole, and both the liquid hole and the air hole have cavities inside. The liquid hole is at an inclined angle, and the air hole is flared and flat.

9. A slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to claim 1, characterized in that, In the cleaning fluid circuit module, the reagent addition system, slide rinsing system, slide blowing system, steel needle internal and external washing system, and waste liquid discharge system are connected in sequence through pipelines.

10. A slide cleaning device adapted to an intraoperative rapid frozen immunohistochemical staining equipment according to claim 7, characterized in that, The cleaning fluid circuit module is connected to the nozzle in the movable slide rail module via a pipe.

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