Constant-speed sample mixing device with closed-loop control

Abstract

The utility model relates to the technical field of medical instruments, in particular to a sample constant-speed uniform mixing device with closed-loop control, which comprises a uniform mixing base plate, a rotating bearing, an eccentric wheel, a driving mechanism, a uniform mixing bearing, a cleaning sleeve, a sampling needle and a reaction cup, the driving mechanism is used for driving the eccentric wheel to rotate, an eccentric hole is formed near the center of the eccentric wheel, a blending bearing is arranged in the eccentric hole, a cleaning sleeve is arranged on the inner ring of the blending bearing, an open hole is formed in the center of the cleaning sleeve, and the sampling needle penetrates through the open hole and vertically slides back and forth along the open hole. The uniform mixing device is simple and reliable in structure, small in size, high in efficiency and not easy to produce more tiny bubbles, and the uniform mixing effect can be accurately controlled, so that the accuracy of a detection result is ensured.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a sample constant-speed mixing device with closed-loop control. Background Technology

[0002] In the field of in vitro diagnostics for medical devices, instruments such as specific protein analyzers, coagulation analyzers, and biochemical analyzers often require thorough mixing of collected body fluid samples such as urine and blood with reagents before the mixture reacts to achieve accurate detection.

[0003] Currently, mixing is typically achieved through methods such as liquid flow suction / expulsion, impeller stirring, and high-frequency eccentric vibration. However, these techniques all have some drawbacks. Liquid flow suction / expulsion can introduce air bubbles into the mixed liquid, affecting the accuracy of the test results. Impeller stirring requires a dedicated station and impeller cleaning devices, making the structure complex. High-frequency eccentric vibration makes it difficult to quantify the intensity and amplitude of the vibration, and due to manufacturing and assembly errors between instruments, it is difficult to ensure the consistency of the mixing effect. Furthermore, when the reaction vessel is large, it takes a long time to achieve a good mixing effect.

[0004] Some instruments use sampling needles to stir and mix the liquid. With this structure, the stirring speed has a great impact on the mixing effect. If the speed is too slow, the desired mixing effect will not be achieved. If the speed is too fast, bubbles will be generated in the liquid, affecting the test results. Utility Model Content

[0005] The purpose of this invention is to provide a sample constant-speed mixing device with closed-loop control, which solves the technical problems of existing sample constant-speed mixing devices with closed-loop control, which have complex structures and difficulty in ensuring the consistency of mixing effect when using liquid path suction and discharge, paddle stirring, high-frequency eccentric vibration and sampling needle stirring for mixing, thus affecting the accuracy of the test results.

[0006] To achieve the above objectives, this utility model provides a sample constant-speed mixing device with closed-loop control, including a mixing substrate, a rotary bearing, an eccentric wheel, a drive mechanism, a mixing bearing, a cleaning sleeve, a sampling needle, and a reaction cup. A through hole is provided near one end of the mixing substrate, and the rotary bearing is installed within the through hole. The eccentric wheel is located on the inner ring of the rotary bearing. The drive mechanism drives the eccentric wheel to rotate. An eccentric hole is provided near the center of the eccentric wheel, and the mixing bearing is installed within the eccentric hole. The cleaning sleeve is located on the inner ring of the mixing bearing. An opening is provided at the center of the cleaning sleeve, through which the sampling needle passes and slides back and forth along the opening. The reaction cup is located below the sampling needle, and the body fluid sample and reagents collected by the sampling needle are added to the reaction cup.

[0007] The driving mechanism includes a motor base, a motor, and a drive wheel. The motor base is fixedly disposed at the other end of the mixing substrate, the motor is fixedly mounted on the motor base, and the drive wheel is rotatably disposed on the motor shaft of the motor.

[0008] A transmission belt is tensioned between the drive wheel and the eccentric wheel, and the drive wheel drives the eccentric wheel to rotate through the transmission belt.

[0009] The drive mechanism further includes a sensor plate and a speed sensor. The sensor plate is fixedly mounted on the drive wheel, and the speed sensor is fixedly mounted on the motor base.

[0010] A retaining ring is provided near the upper end face of the cleaning sleeve, and the retaining ring is used to limit the cleaning sleeve on the axis.

[0011] The sample constant speed mixing device with closed-loop control further includes a mixing cover plate, which is disposed on the mixing substrate and located above the transmission belt and the drive wheel.

[0012] The sample constant-speed mixing device with closed-loop control also includes a control system, which is electrically connected to the speed sensor and the motor, and is located on the side of the reaction cup away from the sampling needle.

[0013] This invention discloses a sample constant-speed mixing device with closed-loop control. A through-hole is provided near one end of the mixing substrate, and a rotary bearing is installed within the through-hole. An eccentric wheel is provided on the inner ring of the rotary bearing. A driving mechanism drives the eccentric wheel to rotate. An eccentric hole is provided near the center of the eccentric wheel, and the mixing bearing is installed within the eccentric hole. A cleaning sleeve is provided on the inner ring of the mixing bearing. An opening is provided at the center of the cleaning sleeve. A sampling needle passes through the opening and slides back and forth along the opening. A reaction cup is provided below the sampling needle. The body fluid sample and reagents collected by the sampling needle are added to the reaction cup. This mixing device has a simple and reliable structure, small size, high efficiency, and is not easily affected by numerous tiny air bubbles. The mixing effect can be precisely controlled, thereby ensuring the accuracy of the test results. Attached Figure Description

[0014] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.

[0015] Figure 1 This is a schematic diagram of the overall structure of the sample constant-speed mixing device with closed-loop control according to the first embodiment of this utility model.

[0016] Figure 2 This is a top view of the sample constant-speed mixing device with closed-loop control according to the first embodiment of this utility model.

[0017] Figure 3 This is the first embodiment of the present utility model. Figure 2 A cross-sectional view along line AA.

[0018] Figure 4 This is a schematic diagram of the eccentric wheel in the first embodiment of this utility model.

[0019] In the figure: 1-Mixing substrate, 2-Rotating bearing, 3-Eccentric wheel, 4-Mixing bearing, 5-Cleaning sleeve, 6-Retaining ring, 7-Transmission belt, 8-Motor base, 9-Motor, 10-Drive wheel, 11-Speed ​​sensor, 12-Sensing plate, 13-Mixing cover plate, 14-Sampling needle, 15-Reaction cup, 16-Control system, 31-Eccentric hole, 51-Opening. Detailed Implementation

[0020] The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, but should not be construed as limiting the present invention.

[0021] First embodiment:

[0022] Please see Figures 1 to 4 This utility model provides a sample constant speed mixing device with closed-loop control, including a mixing substrate 1, a rotary bearing 2, an eccentric wheel 3, a drive mechanism, a mixing bearing 4, a cleaning sleeve 5, a sampling needle 14 and a reaction cup 15, a mixing cover plate 13 and a control system 16. The drive mechanism includes a motor base 8, a motor 9, a drive wheel 10, a sensing plate 12 and a speed sensor 11.

[0023] In this embodiment, the eccentric wheel 3 is driven to rotate by the drive mechanism, causing the sampling needle 14 to oscillate around the axis of the eccentric wheel 3, thereby stirring and mixing the liquid in the reaction cup 15. Simultaneously, the rotational speed of the motor 9 is detected by the speed sensor 11, allowing for accurate, real-time, and constant control of the motor 9's rotational speed based on the volume of the reaction cup 15 and the viscosity of the reagent. This precise and constant control of the mixing speed ensures uniform mixing of the liquid. Furthermore, it achieves closed-loop control, is simple and reliable in structure, small in size, highly efficient, and resistant to numerous microbubbles. The mixing effect is precisely controlled, guaranteeing the accuracy of the test results. Moreover, it eliminates the need for additional paddles for stirring, solving the technical problem of existing sample constant-speed mixing devices with closed-loop control, which suffer from complex structures, difficulty in ensuring consistent mixing effects, and consequently compromised accuracy of test results when using liquid path suction / expulsion, paddle stirring, high-frequency eccentric vibration, and sampling needle 14 stirring.

[0024] The mixing substrate 1 has a through hole near one end, and the rotary bearing 2 is installed inside the through hole. The inner ring of the rotary bearing 2 is provided with the eccentric wheel 3. The driving mechanism is used to drive the eccentric wheel 3 to rotate. An eccentric hole 31 is provided near the center of the eccentric wheel 3. The mixing bearing 4 is provided inside the eccentric hole 31. The inner ring of the mixing bearing 4 is provided with the cleaning sleeve 5. The cleaning sleeve 5 has an opening 51 at its center. The sampling needle 14 passes through the opening 51 and slides back and forth along the opening 51. The reaction cup 15 is provided below the sampling needle 14. The body fluid sample and reagents collected by the sampling needle 14 are added to the reaction cup 15. The cleaning sleeve 5 has an inlet and an outlet. When the liquid flows from the inlet to the outlet of the cleaning sleeve 5 under the action of the pump valve, the cleaning sleeve 5 can clean the outer wall and inner cavity of the sampling needle 14 to prevent cross-contamination between samples.

[0025] Secondly, the other end of the mixing substrate 1 is fixedly provided with the motor base 8, the motor base 8 is fixedly installed with the motor 9, the drive wheel 10 is rotatably provided on the motor shaft of the motor 9, and a transmission belt 7 is tensioned between the drive wheel 10 and the eccentric wheel 3. The drive wheel 10 drives the eccentric wheel 3 to rotate through the transmission belt 7.

[0026] Furthermore, the induction plate 12 is fixedly mounted on the drive wheel 10, and the speed sensor 11 is fixedly mounted on the motor base 8. The speed sensor 11 determines the speed of the motor 9 based on the number of times the induction plate 12 passes by it. When the output shaft of the motor 9 rotates, it drives the drive wheel 10 to rotate along the axis of the output shaft of the motor 9, thereby driving the induction plate 12 to rotate accordingly. When the induction plate 12 rotates, the speed sensor 11 senses the number of times the induction plate 12 passes by it, thereby detecting the mixing speed of the motor 9. Then, the speed sensor 11 feeds the speed signal back to the control system 16, so that the control system 16 compares this speed with the preset speed and adjusts the actual speed of the motor 9 to be equivalent to the preset speed, thereby realizing closed-loop control of the speed of the motor 9, so that the mixing device can mix at a constant preset speed, ensuring that the mixing effect of the sample and reagent is optimally controlled.

[0027] Meanwhile, a retaining ring 6 is provided near the upper end face of the cleaning sleeve 5, and the retaining ring 6 is used to limit the cleaning sleeve 5 on the axis.

[0028] In addition, the mixing cover plate 13 is disposed on the mixing substrate 1 and is located above the transmission belt 7 and the drive wheel 10.

[0029] Finally, the control system 16 is electrically connected to the speed sensor 11 and the motor 9 respectively, and is located on the side of the reaction cup 15 away from the sampling needle 14.

[0030] When using the sample constant-speed mixing device with closed-loop control according to this embodiment, after the sampling needle 14 adds both the body fluid sample and reagent into the reaction cup 15, the sampling needle 14 is kept in the reaction cup 15. At this time, the motor 9 is started, causing the axis of the output shaft of the motor 9 to gradually rotate, thereby driving the drive wheel 10 to rotate along the axis of the output shaft of the motor 9. In turn, the drive wheel 10 drives the eccentric wheel 3 to rotate through the transmission belt 7. At this time, the cleaning sleeve 5 will sway around the circumference of the eccentric wheel 3 due to the eccentric hole 31. The circumferential sway radius is the eccentricity S. When the cleaning sleeve 5 sways, it will drive the sampling needle 14 to sway, thereby achieving stirring and mixing of the liquid in the reaction cup 15. Since the mixing cover plate 13 is provided above the drive wheel 10, the mixing cover plate 13 can cover all the transmission components, achieving a protective and aesthetic effect.

[0031] When the drive wheel 10 rotates along the axis of the output shaft of the motor 9, the rotation of the drive wheel 10 will drive the sensing plate 12 to rotate. During the rotation of the sensing plate 12, the sensing plate 12 will pass through the sensing area of ​​the speed sensor 11. At this time, the speed sensor 11 can determine the speed of the motor 9 based on the number of times the sensing plate 12 passes through. Then, the speed sensor 11 will feed back the speed signal to the control system 16, so that the control system 16 will compare this speed with the preset speed and adjust the actual speed of the motor 9 to be equivalent to the preset speed, thereby realizing closed-loop control of the speed of the motor 9, so that the mixing device can mix at a constant preset speed, ensuring that the mixing effect of the sample and reagent is optimally controlled.

[0032] In summary, by driving the eccentric wheel 3 to rotate through the drive mechanism, the sampling needle 14 oscillates around the axis of the eccentric wheel 3, thereby stirring and mixing the liquid in the reaction cup 15. Simultaneously, the rotational speed of the motor 9 is detected by the speed sensor 11, allowing for accurate, real-time, and constant control of the motor 9's rotational speed based on the volume of the reaction cup 15 and the viscosity of the reagent. This precise and constant control of the mixing speed ensures uniform mixing of the liquid. Furthermore, it achieves closed-loop control, is simple and reliable in structure, small in size, highly efficient, and resistant to numerous microbubbles. The mixing effect is precisely controlled, guaranteeing the accuracy of the test results. Moreover, it eliminates the need for additional paddles for stirring, solving the technical problems of existing sample constant-speed mixing devices with closed-loop control, which suffer from complex structures, inconsistent mixing effects, and compromised accuracy in test results when using liquid path suction / expulsion, paddle stirring, high-frequency eccentric vibration, and sampling needle 14 stirring.

[0033] The above-disclosed embodiments are merely one or more preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art can understand that all or part of the processes for implementing the above embodiments and equivalent changes made in accordance with the claims of this application still fall within the scope of this application.

Claims

1. A sample constant-speed mixing device with closed-loop control, comprising a mixing base plate, characterized in that: a rotating bearing, an eccentric wheel, a driving mechanism, a mixing bearing, a cleaning sleeve, a sampling needle and a reaction cup are further included, a through hole is arranged near one end of the mixing base plate, the rotating bearing is arranged in the through hole, the inner ring of the rotating bearing is provided with the eccentric wheel, the driving mechanism is used for driving the eccentric wheel to rotate, an eccentric hole is arranged near the center of the eccentric wheel, the mixing bearing is arranged in the eccentric hole, the inner ring of the mixing bearing is provided with the cleaning sleeve, an opening is arranged in the central part of the cleaning sleeve, the sampling needle passes through the opening and slides up and down along the opening, the reaction cup is arranged below the sampling needle, and the body fluid sample and reagent taken by the sampling needle are both added into the reaction cup.

2. The sample constant-speed mixing device with closed-loop control according to claim 1, characterized in that: the driving mechanism comprises a motor base, a motor and a driving wheel, the other end of the mixing base plate is fixedly provided with the motor base, the motor is fixedly installed on the motor base, and the motor shaft of the motor is rotationally provided with the driving wheel.

3. The sample constant-speed mixing device with closed-loop control according to claim 2, characterized in that: a transmission belt is arranged between the driving wheel and the eccentric wheel in tension, and the driving wheel drives the eccentric wheel to rotate through the transmission belt.

4. The sample constant-speed mixing device with closed-loop control according to claim 3, characterized in that: the driving mechanism further comprises an inductive sheet and a rotating speed inductor, the inductive sheet is fixedly arranged on the driving wheel, and the rotating speed inductor is fixedly installed on the motor base.

5. The sample constant-speed mixing device with closed-loop control according to claim 1, characterized in that: a retaining ring is arranged near the upper end surface of the cleaning sleeve, and the retaining ring is used for limiting the position of the cleaning sleeve on the axis.

6. The sample constant-speed mixing device with closed-loop control according to claim 3, characterized in that: the sample constant-speed mixing device with closed-loop control further comprises a mixing cover plate, the mixing cover plate is arranged on the mixing base plate and located above the transmission belt and the driving wheel.

7. The sample constant-speed mixing device with closed-loop control according to claim 4, characterized in that: the sample constant-speed mixing device with closed-loop control further comprises a control system, the control system is electrically connected with the rotating speed inductor and the motor respectively, and is located on the side of the reaction cup away from the sampling needle. ​ ​ ​ ​ ​ ​ ​

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