Multi-surface breathable micro-fluidic chip cover

Abstract

The utility model discloses a multi-face breathable microfluidic chip cover, which relates to the technical field of microfluidics, and comprises a plug body, a polyhedral groove is arranged in the plug body, three anti-suction bodies are arranged in the bottom end of the plug body, and the polyhedral groove is used for preventing a microfluidic chip bonding film from being burst open by high pressure. According to the utility model, through the polyhedral groove, the conical interior in the prior art is designed into thirty surfaces, so that the plug body and the chip can be in close fit, the plug body has enough cover opening and closing force, the centrifugal impact force and the amplified impact force of an inner cavity are met, and the design of the thirty surfaces can increase the contact area between the chip cover and the chip, so that the chip cover is more compact. Therefore, the sealing performance is improved.

Description

Technical Field

[0001] This utility model relates to the field of microfluidics technology, and in particular to a multi-faceted breathable microfluidic chip cover. Background Technology

[0002] A microfluidic chip is a chip that allows for the precise manipulation of minute amounts of fluid within microtubes at the micrometer scale, designed to perform various functions of traditional physics, chemistry, or biology experiments at the micrometer scale. The microfluidic chip cap is a crucial component, typically covering the main chip structure to form a closed or semi-closed system. Its primary function is to protect the internal microchannels, reaction chambers, and other structures from external contamination and interference, while ensuring that fluids flow and react within the chip according to predetermined paths and conditions.

[0003] In existing microfluidic chip caps, it's often impossible to achieve a tight seal because doing so would cause the internal pressure to exceed the cap's tolerance. This would lead to separation of the product and cap during centrifugation, resulting in the evaporation of internal droplets. The evaporation of these droplets means the loss of experimental samples, which could lead to biased or completely invalid experimental results. For microfluidic experiments requiring precise control of sample volume and reaction conditions, droplet evaporation directly impacts the accuracy and reliability of experimental data.

[0004] To address the issue of product separation from the cap during centrifugation when the seal is not properly tightened, leading to the evaporation of internal droplets, the conical surface inside the microfluidic chip cap has been optimized into a polyhedron. This design allows for a tighter fit between the cap and the chip, providing sufficient opening and closing force to withstand the impact forces of centrifugation and internal cavity expansion. The polyhedron design increases the contact area between the cap and the chip, thereby improving the reliability of the seal. Compared to a conical surface, the polyhedron structure more effectively prevents fluid leakage or breaching of the seal under high pressure.

[0005] However, during the use of the microfluidic chip cap, the high voltage inside the chip can still exceed the limit. This can cause the microfluidic chip bonding film or the cap to be ruptured during amplification within the internal cavity, leading to droplet mixing and experimental failure. Experimental failure due to droplet mixing means that the obtained data cannot accurately reflect the experimental process, thus preventing the drawing of valid scientific conclusions. Utility Model Content

[0006] The purpose of this invention is to address the shortcomings of existing technologies by proposing a multi-faceted, breathable microfluidic chip cover, which solves the problem that the high pressure inside the chip can still exceed the limit in existing technologies.

[0007] To achieve the above objectives, the present invention adopts the following technical solution:

[0008] A multi-faceted, breathable microfluidic chip cap includes a plug body with multi-faceted grooves inside. Three anti-suction elements are located inside the bottom of the plug body. The multi-faceted grooves prevent the bonding membrane of the microfluidic chip from being ruptured by high pressure. This effectively prevents fluid leakage or rupture of the sealing surface under high pressure.

[0009] As a further improvement of this utility model, a top protective plate is fixedly connected to the top of the plug, and several anti-slip trapezoidal shapes are fixedly connected to the outside of the top protective plate. The anti-slip trapezoidal shapes can prevent the friction between the hand and the top protective plate from increasing, thereby preventing the top protective plate from falling off.

[0010] As a further improvement of this utility model, the thickness of the top protective plate is set to 3.1cm-3.3cm, the overall height of the microfluidic chip cover is set to 10.75cm-10.95cm, and the diameter of the plug is set to 6.4cm-6.6cm. This makes the chip easy to place and fix on the operating table, and also facilitates researchers to observe, test, and manipulate the inside of the chip using equipment such as microscopes.

[0011] As a further improvement of this utility model, the diameter of the top protective plate is set to 9.9cm-10.1cm, the thickness of the anti-slip trapezoidal body is set to 0.9cm-1.1cm, and the diameter of the polyhedral groove at the opening of the plug body is set to 4.2cm-4.4cm. This facilitates hand-held operation by researchers and also makes it easier to place and manage on an experimental table.

[0012] As a further improvement of this utility model, the diameter of the polyhedral groove inside the plug body is set to 3.7cm-3.8cm, the distance between the two ends of the polyhedral groove is set to 8.3cm-8.5cm, and the inclination angle between the two ends of the polyhedral groove is set to 3.4°-3.5°. The distance between the two ends of the polyhedral groove can enhance the overall structural stability of the chip, making it less prone to damage or deformation during experiments. After multiple experimental verifications, the inclination angle between the two ends of the polyhedral groove set to 3.4°-3.5° avoids the problem of the cover being lifted due to low sidewall friction, and also avoids the problem of the microfluidic chip cover being difficult to press and the mold being prone to sticking.

[0013] As a further improvement of this utility model, the anti-slip trapezoidal body is used to prevent slippage when the top protective plate is rotated, and the anti-suction body is used to allow excess high pressure inside the chip to flow out. The anti-suction body effectively releases the high pressure accumulated inside the chip, thereby preventing the chip from being damaged due to excessive internal pressure.

[0014] Compared with the prior art, the advantages of this utility model are as follows:

[0015] 1. By using a multi-faceted groove, the existing conical internal design is transformed into a design with thirty faces. This allows for a tighter fit between the plug and the chip, providing sufficient opening and closing force to withstand the impact forces of centrifugation and internal cavity amplification. The thirty-faceted design increases the contact area between the chip cap and the chip, thereby improving sealing performance. This tight fit helps prevent fluid leakage, ensuring a stable internal environment for the microfluidic chip during centrifugation or internal cavity amplification. Furthermore, by increasing the contact area and changing the shape, the connection between the chip cap and the chip is more robust. This design helps enhance the overall structural strength of the chip, enabling it to withstand greater impact forces, especially during centrifugation, reducing the risk of deformation or damage caused by centrifugal force. The thirty-faceted internal design also facilitates more precise control of fluid flow within the chip. Compared to a conical design, this multi-faceted shape provides a more uniform fluid distribution and a more efficient fluid transport path, thereby improving the analytical performance and efficiency of the microfluidic chip.

[0016] 2. The use of polyhedral grooves, due to their polyhedral design, allows excessive high pressure inside the chip to escape through the gaps between the faces. This prevents the bonding film of the microfluidic chip from being ruptured by high pressure, avoiding defects. The polyhedral design increases the pressure relief channels inside the chip. When high pressure is generated inside the chip, these channels allow high-pressure fluid to flow out through the gaps between the faces, effectively reducing the internal pressure. This design helps prevent the bonding film of the microfluidic chip from being ruptured by high pressure, improving the chip's reliability and stability. The high-pressure fluid flows out through the gaps in the polyhedrons, reducing stress concentration caused by high pressure inside the chip. This helps extend the chip's lifespan and reduces the risk of chip damage or performance degradation due to high pressure. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of this utility model.

[0018] Figure 2 This is a structural schematic diagram of the present invention from another angle.

[0019] In the diagram: 101, top protective plate; 102, anti-slip trapezoidal body; 201, plug; 202, anti-suction body; 203, polyhedral groove. Detailed Implementation

[0020] To make the above-mentioned objectives, features, and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a full understanding of this utility model. However, this utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this utility model. Therefore, this utility model is not limited to the specific embodiments disclosed below.

[0021] It should be noted that when an element is referred to as being "fixed to" another element, it can be directly attached to the other element or there may be an intervening element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.

[0022] See attached document Figure 1 and attached Figure 2 A multi-faceted, breathable microfluidic chip cover includes a top protective plate 101, an anti-slip trapezoidal body 102, a plug 201, an anti-suction body 202, and a multi-faceted groove 203.

[0023] The polyhedral groove 203 inside the plug 201 is designed with thirty faces. After multiple tests, it was found that compared to twenty, forty, and fifty faces, the thirty-face design does not result in excessive airflow or a very tight seal. Furthermore, the thirty faces are very simple to manufacture; a 12-degree grind using a faceted mill is sufficient. Therefore, when the experimenter holds the anti-slip trapezoidal body 102 to control the top protective plate 101 to seal the microfluidic chip, the anti-slip trapezoidal body 102 provides a non-slip effect. The thirty-face design inside the polyhedral groove 203 ensures a tight fit between the cap and the chip, providing sufficient opening and closing force to withstand the impact of centrifugation and internal cavity amplification. It also allows excess high pressure inside the chip to escape through the gaps between the faces, preventing the microfluidic chip's bonding film from being ruptured by high pressure and avoiding defects. The polyhedral design increases the contact area between the chip cap and the chip, thereby improving the sealing performance. This tight fit helps prevent fluid leakage, ensuring a stable internal environment for the microfluidic chip during centrifugation or internal cavity expansion. Simultaneously, the polyhedral structure enhances the overall structural strength of the chip, enabling it to withstand greater impact forces, particularly during centrifugation, significantly reducing the risk of deformation or damage caused by centrifugal forces. Furthermore, allowing high-pressure fluid to flow out through the gaps between the faces of the polyhedral groove 203 effectively manages the internal pressure of the chip. When high pressure is generated inside the chip, these gaps act as additional pressure relief channels, helping to reduce internal pressure and preventing the bonding film of the microfluidic chip from being ruptured due to high pressure. This pressure management capability is crucial for maintaining chip stability and extending its lifespan, especially under high-pressure experimental conditions.

[0024] When the anti-suction element 202 fixed to the bottom of the plug 201 contacts the microfluidic chip, the height of the anti-suction element 202 creates a certain distance between the plug 201 and the microfluidic chip. Inside the microfluidic chip, pressure may be generated due to fluid flow, chemical reactions, or physical effects. Maintaining a certain gap provides a buffer space for these pressures, preventing direct contact between the chip cap and the chip and potential breakage due to pressure. Furthermore, during experiments, the fluid inside the chip may expand or contract with temperature increases or decreases. The gap allows for this volume change, preventing chip breakage or leakage caused by fluid volume changes. A certain gap also makes it easier to remove the chip cap from the chip, facilitating chip maintenance and cleaning. This is particularly important for chips used for extended periods and subjected to repeated experiments. The gap also provides the chip with a degree of flexibility under external stress, allowing it to better adapt to various experimental conditions and environmental changes.

[0025] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A multi-faceted, gas-permeable microfluidic chip cover comprising a plug body (201), characterized in that, The inside of the plug body (201) is provided with a polyhedral groove (203), and the inside of the bottom end of the plug body (201) is provided with three anti-suction bodies (202), and the polyhedral groove (203) is used for preventing the microfluidic chip bonding film from being punched open by high pressure.

2. The multi-faceted, gas-permeable microfluidic chip cover of claim 1, wherein, The top end of the plug body (201) is fixedly connected with a top protective plate (101), and the outside of the top protective plate (101) is fixedly connected with a plurality of anti-skid trapezoidal bodies (102).

3. The multi-faceted, gas-permeable microfluidic chip cover of claim 2, wherein, The thickness of the top protective plate (101) is set to 3.1cm-3.3cm, the overall height of the microfluidic chip cover is set to 10.75cm-10.95cm, and the diameter of the plug body (201) is set to 6.4cm-6.6cm.

4. The multi-faceted, gas-permeable microfluidic chip cover of claim 2, wherein, The diameter of the top protective plate (101) is set to 9.9cm-10.1cm, the thickness of the anti-skid trapezoidal body (102) is set to 0.9cm-1.1cm, and the diameter of the polyhedral groove (203) at the opening of the plug body (201) is set to 4.2cm-4.4cm.

5. The multi-faceted, gas-permeable microfluidic chip cover of claim 2, wherein, The diameter of the polyhedral groove (203) in the inside of the plug body (201) is set to 3.7cm-3.8cm, the distance between the two ends of the polyhedral groove (203) is set to 8.3cm-8.5cm, and the inclination angle between the two ends of the polyhedral groove (203) is set to 3.4°-3.5°.

6. The multi-faceted, gas-permeable microfluidic chip cover of claim 2, wherein, The anti-skid trapezoidal body (102) is used to prevent sliding when the top protective plate (101) is rotated, and the anti-suction body (202) is used to discharge the excess high pressure in the chip.

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