Quantitative sampling electronic pipette

Abstract

A quantitative sampling electronic pipette comprises a pipette body, a battery and a controller, the pipette body is sequentially provided with a control bin, a first gas bin, a pipeline bin, a second gas bin and a pipette head from top to bottom, and the control bin and the first gas bin are separated through an upper airtight partition plate; the first air bin forms an airtight cavity in the gun body through an upper airtight partition plate and a lower airtight partition plate, a pressure sensor and a miniature air pump are arranged in the airtight cavity, and the miniature air pump is fixed to the lower airtight partition plate; a suction air pipe and a pump air outlet pipe penetrate through the pipeline bin; the second gas bin is a bin body in direct contact with the sample liquid, the second gas bin and the pipeline bin are separated through sealing rubber, and the second gas bin is connected with the gun head; the pressure sensor measures the air pressure value in the first air bin in real time, when the pressure value reaches a set value, the micro air pump is closed, air is quantitatively sucked / pumped out through the micro air pump, and the air pressure in the pipette barrel is adjusted, so that a sample is quantitatively sucked into or pressed out of the pipette under the action of air pressure difference.

Description

Technical Field

[0001] This utility model relates to the field of medical testing equipment technology, and in particular to a quantitative sampling electronic pipette. Background Technology

[0002] A pipette is a device used for quantitative transfer of liquids. It is widely used in fields such as biology and chemistry. Precise quantitative pipetting operations are required in scenarios such as biomedical laboratories and hospital testing departments. Electronic pipettes can achieve accurate quantitative pipetting through electrical control.

[0003] For example, patent number ZL2017210668244 discloses an electronically controlled electric pipette, including a body, a reservoir tube, a control box, and a lithium battery. The reservoir tube is located on the bottom of the body, and anti-slip rubber rings are provided around the body. A suction button is located on the side of the body, and the control box is located on top of the body. The control box has a display screen, and control buttons are located next to the display screen. This pipette draws liquid by controlling an air pump to absorb gas from the reservoir tube, and simultaneously dispenses liquid by opening and closing a solenoid valve. It does not require manual operation by the user, making it convenient to use. It uses electronic measurement, and the suction and dispensing volumes are set via the control buttons. A flow detector obtains the flow information during suction and dispensing in real time. When the predetermined suction and dispensing volumes are reached, the control unit controls the solenoid valve to close, thereby controlling the suction and dispensing volumes. No calibration is required, and the measurement is accurate.

[0004] For example, patent number ZL202120228613.6 relates to a detachable electric pipette, including a quantitative pipette and a storage tube. The top of the storage tube is provided with a pipette connector, which is connected to the quantitative pipette via threads. The quantitative pipette body includes a body and a controller. The body includes a control chamber, a suction chamber, and a storage chamber arranged sequentially. The controller is fixed in the control chamber by bolts. The suction chamber is provided with an air pump, an air extraction line, a fixed bracket, and a fixed slot. The air pump is fixed to the fixed bracket by bolts. The air extraction line is embedded in the fixed slot. One end of the air extraction line is connected to the output end of the air pump, and the other end of the air extraction line passes through the suction chamber and the storage chamber and is movably connected to the pipette connector. By adding a storage chamber, damage to the electrical components inside the device due to water is avoided. It does not require manual operation by the operator, uses electronic quantitative measurement, does not require calibration, and is accurate in quantitative measurement. Summary of the Invention

[0005] The problem to be solved by this utility model is to propose a new type of electronic pipette for quantitative sampling, which uses an internal pressure sensor and encoder to precisely control the operation of the air pump in order to achieve high-precision quantitative sampling.

[0006] This utility model provides a quantitative sampling electronic pipette, including a pipette body, a battery, and a controller. The pipette body, from top to bottom, sequentially comprises a control chamber, a first gas chamber, a tubing chamber, a second gas chamber, and a pipette tip.

[0007] The control chamber contains a battery and a controller. The controller is connected to the control board on the outside of the pipette body via a control line. The control chamber and the gas chamber are separated by an upper airtight partition.

[0008] The air chamber is formed by upper and lower airtight partitions within the gun body, and a pressure sensor and a miniature air pump are installed in the airtight cavity. The miniature air pump is controlled by PWM frequency conversion and is fixed on the lower airtight partition. The controller is connected to the miniature air pump through wires and control lines. Sealing measures are taken at the places where the wires and control lines pass through the upper airtight partition.

[0009] The pipeline compartment contains one inhalation pipe and one outlet pipe. The pipeline compartment and the air compartment are separated by a lower airtight partition. All pipes passing through the lower airtight partition are sealed.

[0010] The second air chamber is the chamber that is in direct contact with the sample liquid. The second air chamber and the tubing chamber are separated by a sealing rubber. The second air chamber is connected to the nozzle. Under the action of the air pressure difference between the second air chamber and atmospheric pressure, the sample is drawn into / pumped out of the nozzle.

[0011] The pressure sensor measures the air pressure inside the air chamber in real time. When the pressure reaches the set value, the micro air pump is turned off. The set pressure value is determined by the set pipetting volume. The micro air pump quantitatively draws in / pumps out air to adjust the air pressure inside the pipette, so that the sample is drawn in or expelled from the pipette under the action of the air pressure difference.

[0012] This invention uses a miniature air pump to quantitatively draw in / pump out air, adjusting the air pressure inside the pipette tube so that the sample is drawn in or pumped out of the pipette under the action of the air pressure difference.

[0013] To ensure that the air inside the first gas chamber is dry and clean, and to prevent moisture and aerosols in the sample from entering the first gas chamber with the air and other substances from affecting the accuracy of the air pressure difference measurement, a drying and filtering device is provided at the inlet end of the inhalation tube.

[0014] Preferably, a rotary encoder is installed inside the air chamber. The rotary encoder is connected to a reducer, which is connected to the motor of the micro air pump. The rotary encoder is connected to a controller via a data cable. It is used to measure the speed and rotation angle of the micro air pump motor. Based on the measured data, the controller controls the operation of the micro air pump motor. The reducer improves the stability of the micro air pump during operation.

[0015] By incorporating a pressure sensor and encoder within the pipette, the operating status of the air pump can be precisely controlled, thereby achieving high-precision quantitative sampling. This device helps improve pipetting accuracy and enhances sampling precision during experiments.

[0016] Preferably, the battery is a rechargeable battery, and the power system of the pipette is composed of the rechargeable battery and a miniature air pump.

[0017] Furthermore, a gas pipeline system is formed by one inhalation pipe and one outlet pipe. Each pipe is equipped with a one-way valve to ensure one-way airflow. A drying and filtering device is installed at the end of the inhalation pipe that contacts the air chamber. Sealing measures are taken at the points where each pipe passes through the lower airtight partition and rubber sealing plug.

[0018] Furthermore, one-way valve one is installed in the inhalation air tube, and one-way valve two is installed in the pumping air tube. One-way valve one and one-way valve two are linked together, with only one valve open at a time. One-way valve one and one-way valve two are connected to the controller respectively. When a sample is inhaled, one-way valve one is opened and one-way valve two is closed, and the micro air pump is turned on to draw air from air chamber two into air chamber one. When the pressure value measured by the pressure sensor reaches the set value, the controller turns off the micro air pump. When a sample is pumped out, one-way valve one is closed and one-way valve two is opened, and the micro air pump is turned on to pump air from air chamber one into air chamber two. The sample liquid is pumped out in batches according to the set value, including 10% or 20% of the set capacity. When the pressure value measured by the pressure sensor reaches the set value, the micro air pump is turned off.

[0019] Preferably, inside the air chamber, a pressure sensor is attached to the upper airtight partition at the top of the air chamber to measure the air pressure value inside the air chamber in real time.

[0020] Preferably, the gun head is equipped with a gun head ejection system, which includes a pressure plate, a spring device, and an ejection control key. The pressure plate is installed at the upper end of the gun head to press out the gun head. The spring device passes through the gap between the gun body shell and the chamber and is in a compressed state. The ejection control key is installed on the control plate to eject the gun head and reset it to the compressed state after ejection.

[0021] The advantages of this invention are as follows: By using data feedback from a pressure sensor, the controller adjusts the rotation of the micro air pump motor. Furthermore, a combination of a rotary encoder and a reducer can achieve precise control of the air pump, ensuring sample transfer accuracy, reducing reagent waste and detection errors, improving sampling efficiency, and enabling automated sampling. Through the integration of electronic control, sensor feedback, and intelligent design, the standardization and automation level of pipetting operations are significantly improved, giving it high clinical practical value. Attached Figure Description

[0022] Figure 1This is a schematic diagram of a quantitative sampling electronic pipette.

[0023] Explanation of the labels in the diagram:

[0024] 1—Control compartment; 11—Battery; 12—Controller; 13—Control board;

[0025] 2 – Air chamber one; 21, 22 – Upper and lower airtight partitions;

[0026] 3—Pipeline compartment;

[0027] 31—Inhalation trachea; 311—One-way valve one;

[0028] 32—Pump outlet pipe; 321—One-way air valve two;

[0029] 33—Sealing rubber; 34—Drying and filtering device;

[0030] 4—Gas Chamber Two;

[0031] 5—The spearhead;

[0032] 51—Pressure plate; 52—Spring device;

[0033] 6 – Pressure sensor; 7 – Miniature air pump; 8 – Rotary encoder; 9 – Reducer. Detailed Implementation

[0034] A quantitative sampling electronic pipette includes a pipette body, a battery, and a controller, such as Figure 1 As shown, the gun body is divided into a control compartment 1, a gas compartment 1 2, a pipeline compartment 3, a gas compartment 2 4, and a gun head 5, wherein:

[0035] The control chamber 1 contains a rechargeable battery 11 and a controller 12. The battery 11 is connected to the controller 12 via wires. The controller 12 is connected to the control board 13 on the outside of the pipette body via control lines. The control chamber 1 and the gas chamber 2 are airtightly isolated by an upper airtight partition 21.

[0036] The air chamber 2 is formed by upper and lower airtight partitions 21 and 22 within the gun body to form an airtight cavity. A pressure sensor 6 and a miniature air pump 7 are installed in the airtight cavity. The miniature air pump 7 is controlled by PWM frequency conversion. The miniature air pump 7 is fixed on the lower airtight partition 22. The controller 12 is connected to 7 through wires and control lines. Sealing measures are taken at the places where the wires and control lines pass through the upper airtight partition 21.

[0037] The pipeline compartment 3 is equipped with one inhalation pipe 31 and one outlet pipe 32. The pipeline compartment 3 is airtightly separated from the first air compartment 2 by the lower airtight partition 22, and the pipeline compartment 3 is airtightly separated from the second air compartment 4 by the sealing rubber 33. Each air pipe is sealed at the point where it passes through the lower airtight partition 22, and each air pipe is also sealed at the point where it passes through the sealing rubber 33.

[0038] The second air chamber 4 is a chamber that is in direct contact with the sample liquid. The second air chamber 4 and the pipeline chamber 3 are separated by sealing rubber 33. The second air chamber 4 is connected to the pipette head 5. Under the action of air pressure difference in the second air chamber 4, the sample is sucked in or pumped out of the pipette head 5.

[0039] Pressure sensor 6 measures the air pressure in air chamber 2 in real time. When the pressure reaches the set value, the micro air pump 7 is turned off. The set pressure value is determined by the set volume of liquid. The micro air pump 7 quantitatively draws in / pumps out air to adjust the air pressure in the pipette cavity, so that the sample is drawn in or expelled from the pipette under the action of the air pressure difference.

[0040] The power system of this utility model includes a rechargeable battery 11 and a miniature air pump 7. The battery 11 provides power to the electronic pipette. The battery 11 is connected to a controller 12 via wires. The controller 12 is connected to the miniature air pump 7 via wires and control lines. The controller 12 is connected to a control board 13 on the outside of the main body via control lines.

[0041] The gas pipeline system of this utility model includes one intake pipe 31 and one outlet pipe 32. One-way valve 311 is installed in the intake pipe 31 and one-way valve 321 is installed in the outlet pipe 32. Air can only pass through in one direction. A drying and filtering device 34 is installed at the end of the intake pipe 31 that contacts the air chamber 4. Sealing measures are taken at the places where each pipe passes through the sealing partition.

[0042] The control system of this utility model includes a controller 12, a pressure sensor 6, a rotary encoder 8, a reducer 9, a one-way air valve 311 in the intake air pipe 31, and a one-way air valve 321 in the pump outlet air pipe 32.

[0043] Pressure sensor 6 is installed inside air chamber 2 to measure the air pressure inside the chamber in real time. When the pressure reaches the set value, the micro air pump 7 is turned off. The set pressure value is determined by the set liquid transfer volume according to a certain ratio.

[0044] The rotary encoder 8 is connected to the reducer 9, the reducer 9 is connected to the motor of the miniature air pump 7, and the rotary encoder 8 is connected to the controller 12 via a data cable. The rotary encoder 8 is used to measure the motor speed and rotation angle of the miniature air pump 7. Based on the measured data, the controller 12 controls the operation of the miniature air pump 7. The reducer 8 is used to improve the stability of the miniature air pump during operation.

[0045] One-way air valve 311 and one-way air valve 321 are respectively connected to controller 12 and are linked together. Only one of the two valves is open at a time. When a sample is drawn in, one-way air valve 311 is opened and one-way air valve 321 is closed. The micro air pump is turned on to draw air from air chamber 2 4 into air chamber 2. When the pressure value measured by the pressure sensor reaches the set value, the micro air pump is turned off. When a sample is pumped out, one-way air valve 321 is opened and one-way air valve 2 is closed. The micro air pump is turned on to pump air from air chamber 2 into air chamber 2 4. The sample liquid is pumped out in batches according to the set value, such as 10% or 20% of the set volume. When the pressure value measured by the pressure sensor reaches the set value, the micro air pump 7 is turned off.

[0046] The nozzle ejection system of this utility model includes a pressure plate 51, a spring device 52, and an ejection control key on a control plate 13. The pressure plate 51 is mounted on the upper end of the nozzle 5 and is used to press out the nozzle 5. The spring device 52 passes through the gap between the nozzle shell and the chamber and is connected to the pressure plate 51 and the control plate 13 respectively. When the spring device 52 is in the compressed state, pressing the ejection control key releases the spring energy and ejects the nozzle. After ejection, it returns to the compressed state.

Claims

1. A quantitative sampling electronic pipette comprising a body, a battery and a controller, characterized in that, The gun body is sequentially provided with a control chamber, a gas chamber one, a pipeline chamber, a gas chamber two and a gun head from top to bottom, wherein, The control chamber is provided with a battery and a controller, the controller is connected with a control panel outside the main body of the pipette through a control line, and the control chamber is separated from the gas chamber one by an upper airtight partition plate; The gas chamber one is formed into an airtight cavity in the gun body by the upper and lower airtight partition plates, a pressure sensor and a micro air pump are arranged in the airtight cavity, the micro air pump is controlled by PWM frequency conversion, the micro air pump is fixed on the lower airtight partition plate, and the controller is connected with the micro air pump through an electric wire and a control line, and the electric wire and the control line are sealed at the upper airtight partition plate; The pipeline chamber is provided with one suction air pipe and one pump-out air pipe, the pipeline chamber is separated from the gas chamber one by a lower airtight partition plate, and each air pipe is sealed at the lower airtight partition plate; The gas chamber two is a chamber body directly contacting with a sample liquid, the gas chamber two is separated from the pipeline chamber by a sealing rubber, and the gas chamber two is connected with the gun head, under the action of a gas pressure difference between the gas chamber two and the atmospheric pressure, the sample is sucked into / pumped out of the gun head; The pressure sensor measures the air pressure value in the gas chamber one in real time, the micro air pump is closed when the pressure value reaches a set value, the set pressure value is determined according to a set pipetting amount, the micro air pump is used to quantitatively suck / pump air, the air pressure in the pipeline chamber of the pipette is adjusted, and the sample is quantitatively sucked into or pumped out of the pipette under the action of the gas pressure difference.

2. The electronic fixed-volume pipette of claim 1, wherein, The suction air pipe is provided with a drying filter device at an inlet end.

3. The electronic fixed-volume pipette of claim 1, wherein, A rotary encoder is arranged in the gas chamber one, the rotary encoder is connected with a speed reducer, the speed reducer is connected with a motor of the micro air pump, the rotary encoder is connected with the controller through a data line, the motor rotating speed and the rotating angle of the micro air pump are measured, the controller controls the operation of the micro air pump according to the measured data, and the stability of the micro air pump during operation is improved through the speed reducer.

4. The electronic fixed-volume pipette of claim 1, wherein, The battery is a rechargeable battery, and the rechargeable battery and the micro air pump constitute a power system of the pipette.

5. The electronic pipette according to claim 1 or 2, wherein The gas pipeline system is formed by the suction air pipe and the pump-out air pipe, each air pipe is provided with a one-way air valve, air passes through in one direction, one end of the suction air pipe contacting with the gas chamber two is provided with a drying filter device, and each air pipe is sealed at the lower airtight partition plate and a rubber sealing plug.

6. The electronic fixed-volume pipette of claim 5, wherein, The one-way air valve one is arranged on the suction air pipe, the one-way air valve two is arranged on the pump-out air pipe, the one-way air valve one and the one-way air valve two are connected with each other, only one of the two valves is opened at the same time, the one-way air valve one and the one-way air valve two are connected with the controller respectively, when the sample is sucked, the one-way air valve one is opened, the one-way air valve two is closed, and the micro air pump is started, air in the gas chamber two is sucked into the gas chamber one, the micro air pump is closed after the pressure value measured by the pressure sensor reaches the set value; when the sample is pumped out, the one-way air valve one is closed, the one-way air valve two is opened, and the micro air pump is started, air in the gas chamber one is pumped into the gas chamber two, the sample liquid is pumped out in batches according to the set value at a proportion of 10% set capacity or 20% set capacity, and the micro air pump is closed after the pressure value measured by the pressure sensor reaches the set value.

7. The electronic pipette of claim 1 or 3, wherein, The pressure sensor is attached to the upper airtight partition plate at the top of the gas chamber one, and measures the air pressure value in the gas chamber one in real time.

8. The electronic fixed-volume pipette of claim 1, wherein, The gun head is provided with a gun head ejecting system, which comprises a pressing plate, a spring device and an ejecting control key.

9. The electronic pipette of claim 1 or 3, wherein, The control system of the pipette gun is composed of a controller, a pressure sensor, a rotary encoder, a speed reducer, a one-way air valve one in the suction air pipe and a one-way air valve two in the pump-out air pipe.

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