Tissue specimen fixing device

Abstract

The utility model provides a tissue specimen fixing device which comprises clamping pieces, the clamping pieces are bent to form a clamping space to clamp tissue, or two sets of clamping pieces are arranged, and the two sets of clamping pieces are located on the two sides of the tissue respectively and used for clamping the tissue; the fixing mechanism is installed on the clamping pieces and used for fixing the clamping pieces on the two sides of the tissue, the tissue is clamped and fixed through the clamping pieces, the clamping pieces play a role in shaping, the tissue is flattened, cells of the tissue are made to be relatively compact, the slicing effect of the soaked tissue is improved, and the tissue is not prone to damage. The fixing mechanism is used for fixing the clamping pieces, the tissue is prevented from falling off from a clamping space formed by the clamping pieces, and the stability of tissue fixing is improved; by using the fixing mechanism and the clamping pieces, the weight of the tissue can be increased, the tissue is completely soaked in the soaking liquid, the problem of tissue floating is solved, and the tissue soaking effect is improved.

Description

Technical Field

[0001] This application relates to the field of tissue specimen preparation, and more particularly to a tissue specimen fixation device. Background Technology

[0002] The preparation of tissue specimens mainly assists in clinical diagnosis and treatment.

[0003] This application mainly focuses on the preparation of prostate and tumor specimens.

[0004] The specimens removed from the patient need to be soaked in formalin fixative during the preparation process to coagulate the proteins in the tissue and ensure the integrity of its structure. Then, the fixed specimens are sectioned and finally examined under a microscope.

[0005] During the process of tissue removal and placement in formalin fixative, due to the low density of the tissue, it will float on the surface of the formalin fixative, affecting the fixation of proteins within the tissue. When the tissue is sectioned after soaking, the surface of the tissue is uneven and the cells are relatively loose, which will affect the quality of the section and thus affect the preparation of the tissue slide.

[0006] Therefore, how to design a sample fixation device that facilitates tissue slide preparation and improves slide preparation results has become a technical problem that urgently needs to be solved by those skilled in the art. Utility Model Content

[0007] This application provides a tissue specimen fixation device to at least solve the above-mentioned technical problems existing in the prior art.

[0008] A tissue specimen fixation device is provided, including a clamping piece, which is bent to form a clamping space to clamp the tissue; or, the clamping piece is provided in two sets, which are located on both sides of the tissue respectively, for clamping the tissue.

[0009] The fixing mechanism is installed on the clamping piece to fix the clamping pieces on both sides of the tissue.

[0010] In one embodiment, the clamping sheet is mesh-like, and the density of the clamping sheet is greater than the density of the tissue soaking solution.

[0011] In one embodiment, the fixing mechanism includes a rubber band, which is sleeved on the outside of the clamping pieces on both sides of the tissue so that the clamping pieces fit together to clamp the tissue.

[0012] In one embodiment, the edge of the holding piece is wrapped with a frame, and two sets of holding pieces are provided. When the tissue is fixed, the two holding pieces are located on both sides of the tissue and fit together. The rubber band is sleeved on the outside of the two holding pieces.

[0013] In one embodiment, a notch is provided at the edge of the frame, and a rubber band is secured within the notch.

[0014] In one embodiment, two sets of clamping plates are provided, the edges of the clamping plates are wrapped with a frame, the frame is provided with through holes, and the fixing mechanism passes through the through holes to fix the two clamping plates.

[0015] In one embodiment, the fixing mechanism includes a bolt and a nut. The bolt passes through a through hole in the frame of two clamping plates, the nut of the bolt abuts against one of the clamping plates, and the nut is located on the other side of the clamping plate opposite to the nut. The nut is threadedly connected to the bolt.

[0016] In one possible embodiment, the device includes a first sleeve and a second sleeve. The first sleeve is fixed on one of the clamping pieces and aligned with a through hole, and the second sleeve is fixed on the other clamping piece and aligned with a corresponding through hole. When the tissue is fixed, the first sleeve is inserted into the second sleeve.

[0017] In one embodiment, the clamping piece is made of metal mesh.

[0018] In one embodiment, the clamping piece is circular or polygonal, and the edge is provided with direction marks and / or scale lines.

[0019] Compared with the prior art, the tissue specimen fixation device of this application has the following advantages:

[0020] This application uses a clamping sheet to hold and fix the tissue. The clamping sheet plays a shaping role, flattening the tissue and making the cells of the tissue relatively compact, which improves the slicing effect of the tissue after soaking. The fixing mechanism is used to fix the clamping sheet to prevent the tissue from falling out of the clamping space formed by the clamping sheet, thereby improving the stability of tissue fixation.

[0021] The use of fixation mechanisms and clamping plates can increase the weight of the tissue, allowing it to be completely immersed in the soaking solution, thus solving the problem of tissue floating and improving the soaking effect.

[0022] It should be understood that the description in this section is not intended to identify key or essential features of the embodiments of this application, nor is it intended to limit the scope of this application. Other features of this application will become readily apparent from the following description. Attached Figure Description

[0023] The above and other objects, features, and advantages of exemplary embodiments of this application will become readily apparent from the following detailed description taken in conjunction with the accompanying drawings. Several embodiments of this application are illustrated in the drawings by way of example and not limitation, in which:

[0024] In the accompanying drawings, the same or corresponding reference numerals indicate the same or corresponding parts.

[0025] Figure 1 A schematic diagram of the overall structure of Embodiment 1 of this application is shown;

[0026] Figure 2 A schematic diagram of the unfolded form of Embodiment 1 of this application is shown;

[0027] Figure 3 This paper shows a schematic diagram of the structure of the clamping piece and the frame according to Embodiment 1 of this application;

[0028] Figure 4 A schematic diagram of the overall structure of Embodiment 2 of this application is shown;

[0029] Figure 5 A cross-sectional view of Embodiment 2 of this application is shown;

[0030] Figure 6 A partial cross-sectional view of Embodiment 2 of this application is shown;

[0031] Figure 7 A schematic diagram of the unfolded form of Embodiment 2 of this application is shown;

[0032] Figure 8 A schematic diagram of the structure of Embodiment 3 of this application is shown.

[0033] Explanation of the labels in the diagram:

[0034] 1. Clamping piece; 11. Frame; 111. Notch; 112. Through hole; 113. Direction mark; 114. Scale line;

[0035] 2. Fixing mechanism; 21. Rubber ring; 22. Bolt; 23. Nut;

[0036] 31. First sleeve; 32. Second sleeve. Detailed Implementation

[0037] To make the objectives, features, and advantages of this application more apparent and understandable, the technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0038] Please refer to Figures 1 to 8 As shown.

[0039] Example 1:

[0040] like Figure 1As shown, the device includes a clamping piece 1. In this embodiment, when there is only one clamping piece 1, the clamping piece 1 can be bent or folded in half, and then the tissue is clamped using the clamping piece 1. The device also includes a fixing mechanism 2, which fixes the bent or folded clamping piece 1, thereby enabling the clamping piece 1 to complete the clamping operation on the tissue, thus achieving the fixation of the tissue.

[0041] Using clamping sheet 1 to hold the tissue can help to shape it and solve the problems of uneven tissue surface and relatively loose tissue cells after soaking, which affect the sectioning.

[0042] In this embodiment, the density of the clamping piece 1 is greater than the density of the soaking solution. It should be noted that the soaking solution used in this application is formalin fixative.

[0043] Once the clamping piece 1 has clamped the tissue and fixed it by the fixing mechanism 2, the tissue is placed in the soaking solution and will sink to the bottom of the soaking solution, thus achieving complete immersion of the tissue and solving the problem of tissue floating and not being able to be completely immersed in the prior art.

[0044] To facilitate tissue clamping, since one of the clamping pieces 1 needs to be bent during clamping, tissue clamping is inconvenient. In this embodiment, as follows... Figure 1 and Figure 2 As shown, preferably, the clamping pieces 1 are provided in two sets. When the tissue is fixed, the tissue is located between the two clamping pieces 1, which can achieve the fixation of the tissue.

[0045] After the tissue is fixed by the two clamping pieces 1, in order to prevent the two clamping pieces 1 from moving relative to each other, in this embodiment, the fixing mechanism 2 includes a rubber ring 21. The rubber ring 21 can be simultaneously sleeved on the outside of the two clamping pieces 1, and the tension of the rubber ring 21 can make the two clamping pieces 1 fit together to achieve the purpose of fixing the tissue.

[0046] To improve the stability of the rubber band 21 after it is fixed, in this embodiment, the edge of the clamping piece 1 is wrapped with a frame 11, wherein the edge of the frame 11 is provided with a plurality of notches 111. After the two clamping pieces 1 have completed clamping the tissue, the notches 111 on the two clamping pieces 1 are aligned with each other, and then the rubber band 21 is snapped into the notches 111, thereby improving the stability of the rubber band 21.

[0047] Example 2:

[0048] In this embodiment, two clamping pieces 1 are provided. The clamping pieces 1 are circular metal meshes, and the edges of the clamping pieces 1 are wrapped with a frame 11. The tissue is placed between the two clamping pieces 1, and then the two clamping pieces 1 are fixed by the fixing mechanism 2, thereby fixing the tissue between the two clamping pieces 1.

[0049] Specifically, such as Figure 4 , Figure 5 and Figure 6 As shown, the fixing mechanism 2 includes bolts 22 and nuts 23. The frame 11 is provided with several through holes 112 evenly distributed around the clamping piece 1. When fixing the tissue, the through holes 112 on the two clamping pieces 1 need to be aligned. Then, the bolts 22 are passed through the corresponding screw holes of the two clamping pieces 1 in sequence, so that the nuts of the bolts 22 abut against the surface of one of the frame 11. Then, the nuts 23 are installed on the bolts 22. At this time, the bolts 22 and nuts 23 are threadedly connected.

[0050] To facilitate the installation of the two clamping pieces 1, align the through holes 112 on the two clamping pieces 1, specifically, as follows: Figure 7 As shown, it also includes a first sleeve 31 and a second sleeve 32. The first sleeve 31 is fixedly installed on one of the frame 11 and aligned with its through hole 112. The second sleeve 31 is fixedly installed on the other frame 11 and aligned with its through hole 112.

[0051] In use, simply insert the first sleeve 31 into the second sleeve 31, then the bolt 22 can pass through the first sleeve 31 and the second sleeve 32 in sequence, and then install the nut 23.

[0052] Specifically, in this embodiment, four sets of through holes 112 and fixing mechanisms 2 are provided and are evenly distributed along the circumference of the clamping piece 1.

[0053] In both Embodiment 1 and Embodiment 2, the clamping piece 1 has a circular mesh structure and is made of metal. Here, orientation marks 113 are provided on the frame 11 of the clamping piece 1. The tissue can be aligned with the orientation marks 113 during placement, which makes it easier to identify the orientation of the specimen under microscopic examination.

[0054] Example 3:

[0055] This embodiment is an improvement on embodiment two, but the difference lies in that, as Figure 8 As shown, the clamping piece 1 in this embodiment is rectangular, and the edge of the clamping piece 1 is surrounded by a border 11. The border 11 is provided with direction marks 113 and scale lines 114. The scale lines 114 here can be used to roughly measure the size of the tissue.

[0056] It is worth noting that the mesh structure of the clamping piece 1 allows the tissue to come into complete contact with the soaking solution, thereby improving the soaking effect of the tissue.

[0057] It should be understood that the various forms of processes shown above can be used to rearrange, add, or delete steps. For example, the steps described in this disclosure can be executed in parallel, sequentially, or in different orders, as long as the desired result of the technical solution disclosed in this application can be achieved, and this is not limited herein.

[0058] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "a plurality of" means two or more, unless otherwise explicitly specified.

[0059] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this application should be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.

Claims

1. A tissue specimen fixation device, characterized by, The device comprises clamping pieces (1), two sets of clamping pieces (1) are arranged on both sides of the tissue to clamp the tissue; A fixing mechanism (2) is arranged on the clamping pieces (1) to fix the clamping pieces (1) on both sides of the tissue; The clamping pieces (1) are in a mesh shape, and the density of the clamping pieces (1) is greater than the density of the tissue soaking solution; The edges of the clamping pieces (1) are wrapped with a frame (11), and the frame (11) is provided with direction marks (113) and / or scale lines (114).

2. A tissue specimen fixation device according to claim 1, wherein The fixing mechanism (2) comprises rubber rings (21), which are arranged outside the clamping pieces (1) on both sides of the tissue to make the clamping pieces (1) adhere to each other to clamp the tissue.

3. A tissue specimen fixation device according to claim 1, wherein The frame (11) is provided with notches (111) at the edges, and the rubber rings (21) are clamped in the notches (111).

4. The tissue specimen fixation device of claim 1, wherein The fixing mechanism (2) comprises bolts (22) and nuts (23), the frame (11) is provided with through holes (112), the bolts (22) pass through the through holes (112) of the frames (11) of the two clamping pieces (1), the nuts of the bolts (22) abut against one of the clamping pieces (1), and the nuts (23) are arranged on the other side of the clamping piece (1) relative to the nuts of the bolts (22) and are threadedly connected with the bolts (22).

5. A tissue specimen fixation device according to claim 4, wherein The device comprises first sleeves (31) and second sleeves (32), the first sleeves (31) are fixed on one of the clamping pieces (1) and are aligned with the through holes (112), the second sleeves (32) are fixed on the other clamping piece (1) and are aligned with the corresponding through holes (112), and when the tissue is fixed, the first sleeves (31) are inserted into the second sleeves (32).

6. A tissue specimen fixation device according to claim 1, wherein The clamping pieces (1) are made of metal mesh material.

7. A tissue specimen fixation device according to claim 1, wherein The clamping pieces (1) are in a circular or polygonal shape.

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