Double-balloon fixable animal perfusion device

Abstract

The utility model discloses a double-balloon fixable animal perfusion device which comprises a supporting tube, a fixing device and a fixing device. The isolation plug is placed in the supporting pipe; the end cover is detachably arranged at one end of the supporting pipe, and one end of the end cover is in contact with one end of the isolation plug; the puncture needle penetrates through the supporting tube, the isolation plug and the end cover; the double-balloon assembly comprises a deformable first fixing balloon and a deformable second fixing balloon, one end of the first fixing balloon is connected to the outer wall of the supporting tube in a sealed mode, and a first connecting part is connected between the first fixing balloon and the second fixing balloon; the double-balloon assembly further comprises a supporting cover, a second connecting part is connected between the supporting cover and the second fixing balloon, and a first inlet pipe is connected to the supporting cover. According to the utility model, different use requirements can be conveniently met.

Description

Technical Field

[0001] This utility model relates to the field of animal testing equipment technology, specifically to a double-balloon animal perfusion device. Background Technology

[0002] In animal perfusion experiments, existing perfusion devices are inconvenient to securely fix the part to be perfused, which can easily lead to movement of the perfusion device and thus affect the accuracy and stability of perfusion; in addition, existing perfusion devices have poor flexibility of use. Utility Model Content

[0003] The purpose of this invention is to provide a double-balloon animal infusion device that can fix the animal, thereby improving the flexibility of use and making it easier to meet different usage needs.

[0004] To solve the above-mentioned technical problems, this utility model provides the following technical solution: a dual-balloon animal perfusion device, comprising: a support tube; an isolation plug placed inside the support tube; an end cap detachably disposed at one end of the support tube, with one end of the end cap contacting one end of the isolation plug; a puncture needle passing through the support tube, the isolation plug, and the end cap; a dual-balloon assembly including a deformable first fixation balloon and a second fixation balloon, one end of the first fixation balloon being sealed to the outer wall of the support tube, and a first connecting portion connecting the first fixation balloon and the second fixation balloon; the dual-balloon assembly further comprising a support cover, a second connecting portion connecting the support cover and the second fixation balloon, and a first inlet tube connected to the support cover for connecting an external gas or liquid injection device; a first compression assembly for compressing one end of the second fixation balloon adjacent to the first connecting portion; a second compression assembly for compressing one end of the second fixation balloon adjacent to the second connecting portion; wherein the support cover and the second compression assembly are sealed together.

[0005] Furthermore, the support tube includes: a straight segment one, which is fitted outside the puncture needle and is adapted to the puncture needle; a straight segment two, which is coaxial with the straight segment one; and a conical segment, which is disposed between the straight segment one and the straight segment two; wherein the isolation plug is placed inside the straight segment two, and one end of the isolation plug abuts against the inner wall of the conical segment.

[0006] Furthermore, the first extrusion assembly includes: a first sleeve, which is coaxially disposed outside the support tube, and one end of the first sleeve is fixedly disposed on the conical section; a first extrusion balloon, which is disposed at the other end of the first sleeve, and the first extrusion balloon is sealed to the straight section; wherein, a second inlet pipe is connected to the first sleeve, and the second inlet pipe is used to connect to an external gas injection or liquid injection device.

[0007] Furthermore, the second extrusion assembly includes: a second sleeve, which is coaxially disposed outside the first sleeve, and one end of the second sleeve is fixedly disposed on the conical section; a second extrusion balloon, which is disposed at the other end of the second sleeve and is sealed to the first sleeve; wherein, the support cover is fixedly disposed on the second sleeve, and a third inlet pipe is connected to the second sleeve, the third inlet pipe being used to connect to an external gas injection or liquid injection device.

[0008] Furthermore, the isolation plug is made of rubber or silicone.

[0009] Furthermore, a limiting hole is provided through the end cap, and a sleeve seat is fixedly sleeved on one end of the puncture needle, with one end of the sleeve seat fitting into the limiting hole.

[0010] Furthermore, two fixing rings are provided on the outer wall of the second straight segment.

[0011] Compared with the prior art, the beneficial effects achieved by this utility model are as follows: by expanding the first and second fixing balloons and pressing them against the inner and outer walls of the animal's ventricle respectively, a fixed perfusion device is achieved; at the same time, by setting the first and second compression balloons, it is easy to meet different usage needs, thereby conveniently adapting to animals of different sizes and types and improving the flexibility of use. Attached Figure Description

[0012] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0013] Figure 1 This is an overall schematic diagram of Embodiment 1 of this utility model.

[0014] Figure 2 This is a schematic cross-sectional view of Embodiment 1 of this utility model.

[0015] Figure 3 This is a schematic diagram showing the positions of the first sleeve, the first compression balloon, the second sleeve, and the second compression balloon in Embodiment 1 of this utility model.

[0016] Figure 4 This is a schematic diagram of the installation of the first extrusion assembly and the second extrusion assembly in Embodiment 1 of this utility model.

[0017] Figure 5 This is a schematic diagram of the fit between the end cap and the sleeve seat in Embodiment 1 of this utility model.

[0018] Figure 6 This is a schematic diagram of the inflated state of the first and second fixed balloons in Embodiment 1 of this utility model.

[0019] Figure 7 This is a schematic diagram of the state of the first compression balloon compressing the second fixed balloon in Embodiment 1 of this utility model.

[0020] Figure 8 This is a schematic diagram of the state of the second compression balloon compressing the second fixed balloon in Embodiment 1 of this utility model.

[0021] Figure 9 This is a schematic diagram of the fixing ring installation in Embodiment 3 of this utility model.

[0022] In the diagram: 1. Support tube; 11. Straight segment one; 12. Conical segment; 13. Straight segment two; 131. Fixing ring; 2. Puncture needle; 3. Double balloon assembly; 31. First fixing balloon; 32. First connecting part; 33. Second fixing balloon; 34. Second connecting part; 35. Support cover; 36. First inlet tube; 4. First compression assembly; 41. First compression balloon; 42. First sleeve; 43. Second inlet tube; 5. Second compression assembly; 51. Second compression balloon; 52. Second sleeve; 53. Third inlet tube; 6. End cap; 61. Limiting hole; 7. Sleeve seat; 8. Isolation plug. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Example 1

[0025] Please see Figures 1-8This utility model provides a technical solution: a double-balloon animal perfusion device, comprising a support tube 1 and a puncture needle 2. The support tube 1 is composed of a straight section 11, a conical section 12, and a second straight section 13, which are coaxial. A detachable end cap 6 is provided at the end of the second straight section 13 away from the conical section 12. The end cap 6 has a cylindrical structure, and a limiting hole 61 is provided at the center of the end cap 6, which is coaxial with the end cap 6. The puncture needle 2 passes through the straight section 11, the conical section 12, and the second straight section 13, and penetrates the limiting hole 61 on the end cap 6. An isolation plug 8 is placed inside the support tube 1. The puncture needle 2 passes through the isolation plug 8, which is made of rubber or silicone. The isolation plug 8 clamps the puncture needle 2, thus fixing it in place. Specifically, the isolation plug 8 is placed in the straight section 13, and a part of the isolation plug 8 abuts against the inner wall of the conical section 12, while one end of the end cap 6 abuts against the isolation plug 8. At the same time, the puncture needle 2 is adapted to the straight section 11. One end of the puncture needle 2 is pointed and extends slightly beyond the straight section 11. The other end of the puncture needle 2 is fixedly fitted with a sleeve seat 7. A part of the sleeve seat 7 abuts against the end face of the end cap 6, and one end of the sleeve seat 7 fits into the limiting hole 61.

[0026] The infusion device also includes a dual-balloon assembly 3, a first compression assembly 4, and a second compression assembly 5. The dual-balloon assembly 3 includes a first fixed balloon 31 and a second fixed balloon 33. The first fixed balloon 31 is located near the end of the straight segment 11 away from the conical segment 12. A first connecting portion 32 is provided between the first fixed balloon 31 and the second fixed balloon 33. The dual-balloon assembly 3 also includes a support cover 35, which is sealed to the second compression assembly 5. A second connecting portion 34 is provided between the support cover 35 and the second fixed balloon 33. The first fixed balloon 31, the second fixed balloon 33, the first connecting portion 32, and the second connecting portion 34 are all sleeved on the outside of the straight segment 11. The first fixed balloon 31 and the second fixed balloon 33 are deformable, while the first connecting part 32, the second connecting part 34, and the support cover 35 are not deformable. A first inlet pipe 36 is connected to the support cover 35. The first inlet pipe 36 is used to connect to an external gas injection or liquid injection device to introduce gas or liquid into the double balloon assembly 3, thereby inflating the first fixed balloon 31 and the second fixed balloon 33. At the same time, the external gas injection device removes the gas from the double balloon assembly 3 (the external liquid injection device can remove the liquid from the gas in the double balloon assembly 3). When the gas or liquid in the double balloon assembly 3 is removed again, the first fixed balloon 31 and the second fixed balloon 33 can deflate again.

[0027] The first compression assembly 4 includes a first sleeve 42 coaxially disposed outside the support tube 1, one end of which is fixedly disposed on the outer wall of the conical section 12; the first sleeve 42 consists of a straight tube portion and a tapered tube portion, the tapered tube portion being fixedly disposed on the outer wall of the conical section 12, and the straight tube portion being sleeved on the outside of the straight section 11; a first compression balloon 41 is disposed at the end of the first sleeve 42 away from the conical section 12, and the first compression balloon 41 is sealed to the outer wall of the straight section 11; the first compression balloon 41 is located at the first Inside the second fixed balloon 33, and the second compression balloon 51 is adjacent to the end of the second fixed balloon 33 connected to the first connecting part 32; a second inlet pipe 43 is connected to the first sleeve 42, the second inlet pipe 43 penetrates the support pipe 1, and the second inlet pipe 43 is sealed to the support pipe 1; the second inlet pipe 43 is used to connect to an external gas injection or liquid injection device, thereby realizing the inflation of the first compression balloon 41; at the same time, the external gas injection device removes the gas or the liquid injection device removes the liquid, thereby causing the first compression balloon 41 to deflate again.

[0028] The second compression assembly 5 includes a second sleeve 52 coaxially disposed outside the first sleeve 42. One end of the second sleeve 52 is fixedly disposed on the conical section 12. A second inlet pipe 43 penetrates the second sleeve 52 and is sealed to the second sleeve 52. The second sleeve 52 is also composed of a straight pipe section and a conical pipe section. A support cover 35 is fixedly disposed on the conical pipe section of the second sleeve 52. A second compression balloon 51 is disposed at the end of the second sleeve 52 away from the conical section 12. The second compression balloon 51 is sealed to the outer wall of the first sleeve 42. The second compression balloon 51 is located inside the second fixed balloon 33 and is adjacent to the end of the second fixed balloon 33 connected to the second connecting part 34. A third inlet pipe 53 is connected to the second sleeve 52. The third inlet pipe 53 is also used to connect to an external gas injection or liquid injection device to inflate the second compression balloon 51. At the same time, the external gas injection device removes the gas or the liquid injection device removes the liquid, so that the second compression balloon 51 deflates again.

[0029] The external gas injection or liquid injection devices connected to the first inlet pipe 36, the second inlet pipe 43, and the third inlet pipe 53 all adopt existing technologies and can realize functions such as gas supply and extraction or liquid injection and extraction. They also have the function of controlling the flow rate. Specifically, they can be implemented by pumps, control valves, sensors, etc., which are existing and will not be described in detail here.

[0030] When using this perfusion device, first, the animal's thoracic cavity is opened, the ventricle is located, and the puncture needle 2, together with the support tube 1, the first fixing balloon 31, and the first connecting part 32, is inserted into the left ventricle. This places the first fixing balloon 31 and the second fixing balloon 33 inside and outside the ventricle, respectively. At this time, gas or liquid is introduced into the double balloon assembly 3 through an external gas injection or liquid injection device, causing the first fixing balloon 31 and the second fixing balloon 33 to inflate. This allows the first fixing balloon 31 and the second fixing balloon 33 to abut against the inner and outer walls of the animal's left ventricle, thereby fixing the entire perfusion device. The length of the first connecting part 32 can be set to 0.1-10mm, and can be set to a suitable range according to the actual application. Meanwhile, since a first compression balloon 41 and a second compression balloon 51 are also provided, the first compression balloon 41 and the second compression balloon 51 are respectively used to compress the two ends of the second fixing balloon 33. When the second fixing balloon 33 inflates, the first compression balloon 41 inflates, and the second compression balloon 51 does not inflate, the first compression balloon 41 compresses the end of the second fixing balloon 33 adjacent to the first connecting part 32, causing deformation towards the first fixing balloon 31. Figure 7 In the state shown, the distance between the first fixing balloon 31 and the second fixing balloon 33 is reduced, thereby fixing the entire perfusion device to the ventricle with a relatively thin wall. When the second fixing balloon 33 inflates, the second compression balloon 51 inflates, and the first compression balloon 41 does not inflate, the second compression balloon 51 compresses the end of the second fixing balloon 33 near the second connecting part 34, causing deformation, i.e. Figure 8 In the state shown, the second fixing balloon 33 is pulled. The end of the second fixing balloon 33 adjacent to the first connecting part 32 can reduce the squeezing effect on the animal's ventricle, thereby making it easier to adapt to the ventricle with a larger wall thickness and avoiding excessive pressure on the animal's ventricle.

[0031] After the first fixation balloon 31 and the second fixation balloon 33 are respectively pressed against the inner and outer walls of the animal's left ventricle, the puncture needle 2 is pulled out through the cannula seat, leaving the support tube 1, the first fixation balloon 31, etc. in the animal's ventricle; and when the puncture needle 2 is removed from the isolation plug 8, the isolation plug 8 automatically closes (the isolation plug 8 is made of rubber or silicone); then, through the needle of the injector passing through the end cap 6 and the isolation plug 8, physiological saline can be injected into the support tube 1 to carry out subsequent perfusion work.

[0032] The perfusion device causes the first fixation balloon 31 and the second fixation balloon 33 to expand, and the first fixation balloon 31 and the second fixation balloon 33 respectively abut against the inner and outer walls of the animal's ventricle, thereby fixing the perfusion device. In addition, by setting the first compression balloon 41 and the second compression balloon 51, compared with the traditional double balloon perfusion device, it is easier to meet different usage needs, thus making it easier to adapt to animals of different sizes and types and improving the flexibility of use.

[0033] Example 2

[0034] Please see Figures 1-8 Based on Embodiment 1, this embodiment specifically connects and fixes the end cap 6 and the straight segment 13 by screws or buckles, thereby facilitating the disassembly of the end cap 6. After the end cap 6 is disassembled, it is convenient to remove and replace the isolation plug 8, thus avoiding the isolation plug 8 from failing to automatically close and seal when the puncture needle 2 penetrates the isolation plug 8 multiple times and is pulled out, that is, ensuring that the isolation plug 8 can automatically close and seal when the puncture needle 2 is pulled out.

[0035] Example 3

[0036] Please see Figures 1-9 Based on Embodiment 2, this embodiment has two fixing rings 131 fixedly installed on the outer wall of the second straight segment 13. The two fixing rings 131 allow the entire infusion device to be held stably by passing fingers through them, thus facilitating its use.

[0037] Finally, it should be noted that the above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A dual-balloon immobilizable animal perfusion device, comprising: The utility model relates to a kind of double-balloon catheter, including: Support tube (1); Isolation plug (8), the isolation plug (8) is placed inside the support tube (1); End cap (6), the end cap (6) is detachably arranged in one end of the support tube (1), and one end of the end cap (6) is in contact with one end of the isolation plug (8); Puncture needle (2), the puncture needle (2) passes through the support tube (1), isolation plug (8) and end cap (6); Double-balloon assembly (3), the double-balloon assembly (3) includes deformable first fixed balloon (31), second fixed balloon (33), one end of the first fixed balloon (31) is sealingly connected on the outer wall of the support tube (1), and first connecting portion (32) is connected between the first fixed balloon (31) and the second fixed balloon (33);The double-balloon assembly (3) further includes support cover (35), and second connecting portion (34) is connected between the support cover (35) and the second fixed balloon (33), and first inlet pipe (36) is connected on the support cover (35), and the first inlet pipe (36) is used to connect external gas injection or liquid injection device; First extrusion assembly (4), the first extrusion assembly (4) is used to extrude one end of the second fixed balloon (33) adjacent to the first connecting portion (32); Second extrusion assembly (5), the second extrusion assembly (5) is used to extrude one end of the second fixed balloon (33) adjacent to the second connecting portion (34); Wherein, the support cover (35) is sealingly connected with the second extrusion assembly (5).

2. The dual-balloon secureable animal perfusion device of claim 1, wherein, The support tube (1) includes: Straight line segment one (11), the straight line segment one (11) is set on the puncture needle (2) outside, and the straight line segment one (11) is matched with the puncture needle (2); Straight line segment two (13), the straight line segment two (13) is coaxial with the straight line segment one (11); Conical section (12), the conical section (12) is arranged between straight line segment one (11) and straight line segment two (13); Wherein, the isolation plug (8) is placed in the straight line segment two (13), and one end of the isolation plug (8) is in contact with the inner wall of the conical section (12).

3. The dual-balloon secureable animal perfusion device of claim 2, wherein, The first extrusion assembly (4) includes: First sleeve (42), the first sleeve (42) is coaxially arranged outside the support tube (1), and one end of the first sleeve (42) is fixedly arranged on the conical section (12); First extrusion balloon (41), the first extrusion balloon (41) is arranged on the other end of the first sleeve (42), and the first extrusion balloon (41) is sealingly connected with the straight line segment one (11); Wherein, the first sleeve (42) is connected with second inlet pipe (43), and the second inlet pipe (43) is used to connect external gas injection or liquid injection device.

4. The dual-balloon secureable animal perfusion device of claim 3, wherein, The second extrusion assembly (5) includes: Second sleeve (52), the second sleeve (52) is coaxially arranged outside the first sleeve (42), and one end of the second sleeve (52) is fixedly arranged on the conical section (12); A second extrusion balloon (51) is arranged at the other end of the second sleeve (52), and the second extrusion balloon (51) is sealingly connected with the first sleeve (42); Wherein, the support cover (35) is fixedly arranged on the second sleeve (52), and a third inlet pipe (53) is connected to the second sleeve (52), and the third inlet pipe (53) is used for connecting an external gas injection or liquid injection device.

5. The dual-balloon secureable animal perfusion device of claim 1, wherein, The isolation plug (8) is made of rubber or silicone.

6. The dual-balloon secureable animal perfusion device of claim 1, wherein, A limiting hole (61) is arranged through the end cover (6), one end of the puncture needle (2) is fixedly sleeved with a sleeve seat (7), and one end of the sleeve seat (7) is matched in the limiting hole (61).

7. The dual-balloon secureable animal perfusion device of claim 2, wherein, Two fixed rings (131) are arranged on the outer wall of the straight section two (13).

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