Clavulanic acid hypha treatment device

Abstract

The utility model discloses a clavulanic acid hypha treatment device which comprises a treatment tank and a steam generator, a first steam conveying pipe is connected between the treatment tank and the steam generator, a dehydration structure is connected to the treatment tank, a supporting frame is connected to the dehydration structure, and a five-effect evaporator is connected to the dehydration structure; when the device is used, clavulanic acid and hypha mixed liquid and lime milk can be placed in the treatment tank and are mixed for coagulation and precipitation, and the coagulation and precipitation speed can be increased by adding steam into the steam generator in the process, so that other impurities such as protein and inorganic salt in the clavulanic acid and hypha mixed liquid can be separated, and the clavulanic acid and hypha mixed liquid can be recycled. The method comprises the following steps: firstly, extracting and purifying clavulanic acid, then conveying a mixed solution subjected to coagulation and precipitation to a filter press for solid-liquid separation, and concentrating the separated liquid by using a five-effect evaporator, so that target components such as clavulanic acid and the like are concentrated, and subsequent extraction and purification steps are facilitated.

Description

Technical Field

[0001] This utility model relates to the technical field of clavulanic acid treatment equipment, specifically a clavulanic acid mycelium treatment device. Background Technology

[0002] Clavulanic acid is a derivative of β-lactam antibiotics produced by fungi and has unique pharmacological effects. During fermentation, clavulanic acid mycelia grow in a specific culture medium, which is a liquid composed of various nutrients to provide the mycelia with the necessary carbon source, nitrogen source, inorganic salts, etc. to support their growth and metabolic activities.

[0003] In the existing technology, mycelia are the main producers in the fermentation process of clavulanic acid, producing clavulanic acid through metabolism. However, in addition to clavulanic acid and mycelia, the fermentation broth also contains many other components, such as inorganic salts and proteins. If these are not removed in time, they will affect the extraction efficiency and purity of clavulanic acid. Therefore, a clavulanic acid mycelia treatment device is needed to meet people's needs. Utility Model Content

[0004] The purpose of this invention is to provide a clavulanic acid mycelium treatment device to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a clavulanic acid mycelium treatment device, comprising a treatment tank and a steam generator; a steam delivery pipe is connected between the treatment tank and the steam generator; a dehydration structure is connected to the treatment tank; a support frame is connected to the dehydration structure; a five-effect evaporator is connected to the dehydration structure; a receiving structure is installed inside the support frame; a drying chamber is connected to the receiving structure; a drying structure is installed inside the drying chamber; and stirring structures are installed inside the receiving structure, the treatment tank, and the drying chamber.

[0006] Preferably, the processing tank is equipped with a feed port and a pressure relief valve, and the feed port is connected to the processing tank.

[0007] Preferably, the dehydration structure includes a conveying pipe, one end of which is connected to the discharge end of the processing tank, and the other end of which is connected to a filter press. The feed end of the filter press is connected to the conveying pipe, and the liquid outlet end of the filter press is connected to a connecting pipe, which is connected to a five-effect evaporator. A conveying pump is connected to the conveying pipe.

[0008] Preferably, the receiving structure includes an acid hydrolysis receiving box located below the filter press and installed inside the support frame. One end of the acid hydrolysis receiving box is connected to a second conveying pipe, and the other end of the second conveying pipe is connected to the drying chamber. A second conveying pump is connected to the second conveying pipe.

[0009] Preferably, the drying structure includes a second steam conveying pipe connected to a steam generator. One end of the second steam conveying pipe passes through the drying chamber and is connected to one end of a spiral heat exchange tube. The other end of the spiral heat exchange tube passes through the drying chamber, and an exhaust pipe is installed on the top side of the drying chamber.

[0010] Preferably, a feeding motor and a discharge pipe are respectively installed on both sides of the drying chamber. A connecting shaft is installed at the output end of the feeding motor, and a spiral blade is fixedly sleeved on the connecting shaft. The spiral blade is in contact with the discharge pipe and the inner wall of the drying chamber.

[0011] Preferably, the stirring structure has three parts, each including a stirring motor, with stirring rods installed at the output end of the stirring motor, and the three stirring rods are respectively located inside the corresponding processing tank, drying chamber, and acid hydrolysis receiving box.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] (1) In this utility model, when in use, the clavulanic acid mycelium mixture and lime milk can be placed in a treatment tank to mix and coagulate and precipitate. During the process, steam can be added by a steam generator to increase the speed of coagulation and precipitation, so as to separate other impurities such as proteins and inorganic salts in the clavulanic acid mycelium mixture, which helps to extract and purify clavulanic acid. Then, the mixture after coagulation and precipitation is sent to a filter press for solid-liquid separation. The separated liquid is then concentrated using a five-effect evaporator, so that the target components such as clavulanic acid can be concentrated, which is convenient for subsequent extraction and purification steps.

[0014] (2) The filter residue produced during the filter press will fall into the acid hydrolysis receiving box. Nitric acid can be added to the acid hydrolysis receiving box and mixed with the filter residue to acid hydrolyze the filter residue, oxidize and degrade the high molecular organic matter in the filter residue. After acid hydrolysis treatment, it is transported to the drying chamber. At the same time, the steam generator is turned on to send steam into the drying chamber to dry the acid hydrolyzed residue, reduce its moisture content, and facilitate subsequent crushing, mixing, packaging and other processing steps. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of a clavulanic acid mycelium treatment device proposed in this utility model;

[0016] Figure 2 This is a top view of a clavulanic acid mycelium treatment device proposed in this utility model;

[0017] Figure 3 This is a cross-sectional view of the treatment tank of a clavulanic acid mycelium treatment device proposed in this utility model;

[0018] Figure 4This is a schematic diagram of the support frame structure of a clavulanic acid mycelium treatment device proposed in this utility model;

[0019] Figure 5 This is a schematic diagram of the drying chamber structure of a clavulanic acid mycelium treatment device proposed in this utility model;

[0020] Figure 6 This is a cross-sectional view of the drying chamber of a clavulanic acid mycelium treatment device proposed in this utility model.

[0021] In the diagram: 100, processing tank; 101, steam generator; 102, steam conveying pipe one; 103, support frame; 104, five-effect evaporator; 105, drying chamber; 106, feeding port; 107, pressure relief valve; 200, conveying pipe one; 201, filter press; 202, connecting pipe; 203, conveying pump one; 300, acidolysis receiving box; 301, conveying pipe two; 302, conveying pump two; 400, steam conveying pipe two; 401, spiral heat exchanger tube; 402, exhaust pipe; 403, feeding motor; 404, connecting shaft; 405, spiral blade; 406, discharge pipe; 500, stirring motor; 501, stirring rod. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Example 1: Please refer to Figure 1-6 This utility model provides a technical solution: a clavulanic acid mycelium treatment device, including a treatment tank 100 and a steam generator 101; a steam conveying pipe 102 connects the treatment tank 100 and the steam generator 101; a dehydration structure is connected to the treatment tank 100; a support frame 103 is connected to the dehydration structure; a five-effect evaporator 104 is connected to the dehydration structure; a receiving structure is installed inside the support frame 103; a drying chamber 105 is connected to the receiving structure; a drying structure is installed inside the drying chamber 105; a stirring structure is installed inside the receiving structure, the treatment tank 100, and the drying chamber 105. In use, a clavulanic acid mycelium mixture and lime milk can be added to the treatment tank 100, and the stirring structure and the steam generator 101 can be used to accelerate its coagulation and precipitation. Then, the mixture is transported to the dehydration structure for solid-liquid separation. The separated liquid is concentrated using the five-effect evaporator 104, while the solid is collected using the receiving structure and acidified. After treatment, the residue is dried and recovered using the drying structure.

[0024] Furthermore, the processing tank 100 is equipped with a feed port 106 and a pressure relief valve 107. The feed port 106 is connected to the processing tank 100 and can be used to add materials into the processing tank 100. The pressure relief valve 107 can be used to relieve pressure and cool down.

[0025] Furthermore, the dehydration structure includes a conveying pipe 200, one end of which is connected to the discharge end of the processing tank 100, and the other end of which is connected to a filter press 201. The feed end of the filter press 201 is connected to the conveying pipe 200, and the liquid outlet end of the filter press 201 is connected to a connecting pipe 202, which is connected to a five-effect evaporator 104. A conveying pump 203 is connected to the conveying pipe 200. After coagulation and sedimentation, the liquid that has undergone coagulation and sedimentation is conveyed to the filter press 201 through the conveying pipe 200 by the conveying pump 203. The filter press 201 performs solid-liquid separation on the liquid, and the separated liquid flows into the five-effect evaporator 104 through the connecting pipe 202. The five-effect evaporator 104 then evaporates and concentrates the liquid.

[0026] Furthermore, the receiving structure includes an acid hydrolysis receiving box 300, which is located below the filter press 201 and installed inside the support frame 103. One end of the acid hydrolysis receiving box 300 is connected to a second conveying pipe 301, and the other end of the second conveying pipe 301 is connected to the drying chamber 105. A second conveying pump 302 is connected to the second conveying pipe 301. The slag produced by the filter press will fall into the acid hydrolysis receiving box 300. Nitric acid can be added to the acid hydrolysis receiving box 300 for acid hydrolysis. After acid hydrolysis, the liquid can be transported to the drying chamber 105 through the second conveying pipe 301 by the second conveying pump 302.

[0027] Furthermore, the drying structure includes a second steam conveying pipe 400, which is connected to the steam generator 101. One end of the second steam conveying pipe 400 passes through the drying chamber 105 and is connected to one end of the spiral heat exchange tube 401. The other end of the spiral heat exchange tube 401 passes through the drying chamber 105. An exhaust pipe 402 is installed on the top side of the drying chamber 105. When the steam generator 101 is turned on, steam is conveyed into the spiral heat exchange tube 401 through the second steam conveying pipe 400, so that the steam heats the material residue mixture in the drying chamber 105 and dries the filter residue.

[0028] Furthermore, a feeding motor 403 and a discharge pipe 406 are respectively installed on both sides of the drying chamber 105. A connecting shaft 404 is installed at the output end of the feeding motor 403. A spiral blade 405 is fixedly sleeved on the connecting shaft 404. The spiral blade 405 contacts the discharge pipe 406 and the inner wall of the drying chamber 105. When the feeding motor 403 is turned on, it drives the connecting shaft 404 and the spiral blade 405 to rotate, which can transport the dried residue out.

[0029] Furthermore, the mixing structure has three components, including a mixing motor 500. The output end of the mixing motor 500 is equipped with a mixing rod 501. The three mixing rods 501 are located inside the corresponding processing tank 100, drying chamber 105, and acid hydrolysis receiving box 300, respectively. By turning on the mixing motor 500 at the corresponding position, the corresponding mixing rod 501 can be driven to rotate, which can be used to stir the materials inside the processing tank 100, drying chamber 105, and acid hydrolysis receiving box 300 to promote material mixing.

[0030] The working principle is as follows: During use, the clavulanic acid mycelium mixture and lime slurry are added to the treatment tank 100. Turning on the stirring motor 500 on the treatment tank 100 drives the stirring rod 501 to rotate, agitating the mixture and lime slurry within the treatment tank 100, causing them to mix and coagulate / precipitate. Simultaneously, the steam generator 101 can be turned on, allowing steam to be delivered into the treatment tank 100 via the steam delivery pipe 102, accelerating the coagulation and precipitation of the clavulanic acid mycelium and other substances in the mixture. After coagulation and precipitation, the mixture is transported... Pump 203 delivers the coagulated and precipitated liquid to filter press 201 via conveying pipe 200. Filter press 201 performs solid-liquid separation. The separated liquid flows through connecting pipe 202 into five-effect evaporator 104, where it is further evaporated and concentrated. The residue from the filter press falls into acid hydrolysis receiving tank 300. Nitric acid can be added to the acid hydrolysis receiving tank 300, and the stirring motor 500 on one side of the tank is activated to drive the corresponding agitator. The stirring rod 501 rotates, agitating the filter residue and nitric acid in the acidolysis receiving box 300, thus mixing and acidolyzing them. Acidolysis oxidizes and degrades the high-molecular-weight organic matter in the filter residue. After acidolysis, the filter residue mixture is pumped by pump 302 through conveying pipe 301 to the drying chamber 105. Simultaneously, the steam generator 101 is activated to deliver steam through steam conveying pipe 400 into the spiral heat exchanger tube 401, heating the filter residue mixture in the drying chamber 105. The filter residue is dried. During the process, the stirring motor 500 on the drying chamber 105 can be turned on to drive the stirring rod 501 to rotate, stirring the mixture of material and residue in the drying chamber 105 so that it can fully contact the spiral heat exchange tube 401, thereby improving the heat exchange and drying effect. During the drying process, the discharge pipe 406 can be blocked to prevent leakage. After completion, the discharge pipe 406 can be opened and the feeding motor 403 can be turned on, so that the feeding motor 403 drives the connecting shaft 404 and the spiral blade 405 to rotate, thereby conveying the dried material and residue out.

[0031] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A clavulanic acid mycelium treatment apparatus comprising a treatment tank (100) and a steam generator (101); characterized by: The processing tank (100) is connected with the steam generator (101) with a steam delivery pipe (102), the processing tank (100) is connected with a dehydration structure, the dehydration structure is connected with a support frame (103), the dehydration structure is connected with a five-effect evaporator (104), the inside of the support frame (103) is provided with a receiving structure, the receiving structure is connected with a drying bin (105), the inside of the drying bin (105) is provided with a drying structure, the inside of the receiving structure, the processing tank (100) and the drying bin (105) are provided with stirring structures.

2. A clavulanic acid filament processing apparatus according to claim 1, wherein: The processing tank (100) is provided with a feeding port (106) and a pressure relief valve (107), and the feeding port (106) is communicated with the processing tank (100).

3. The clavulanic acid filament processing apparatus according to claim 1, wherein: The dehydration structure comprises a delivery pipe (200), one end of the delivery pipe (200) is connected to the discharge end of the processing tank (100), the other end of the delivery pipe (200) is connected with a filter press (201), the inlet end of the filter press (201) is communicated with the delivery pipe (200), the outlet end of the filter press (201) is connected with a connecting pipe (202), the connecting pipe (202) is connected to the five-effect evaporator (104), and the delivery pipe (200) is connected with a delivery pump (203).

4. The clavulanic acid filament processing apparatus according to claim 1, wherein: The receiving structure comprises an acidolysis receiving tank (300), the acidolysis receiving tank (300) is located below the filter press (201), the acidolysis receiving tank (300) is installed in the inside of the support frame (103), one end of a delivery pipe (301) is connected to the acidolysis receiving tank (300), the other end of the delivery pipe (301) is connected to the drying bin (105), and a delivery pump (302) is connected to the delivery pipe (301).

5. The clavulanic acid filament processing apparatus according to claim 1, wherein: The drying structure comprises a steam delivery pipe (400), the steam delivery pipe (400) is connected to the steam generator (101), one end of the steam delivery pipe (400) penetrates through the drying bin (105) and is connected with one end of a spiral heat exchange pipe (401), the other end of the spiral heat exchange pipe (401) penetrates through the drying bin (105), and an exhaust pipe (402) is installed on the top side of the drying bin (105).

6. The clavulanic acid filament processing apparatus according to claim 1, wherein: The two sides of the drying bin (105) are respectively provided with a feeding motor (403) and a discharge pipe (406), a connecting shaft (404) is installed on the output end of the feeding motor (403), a spiral blade (405) is fixedly sleeved on the connecting shaft (404), and the spiral blade (405) is in contact with the inner wall of the discharge pipe (406) and the drying bin (105).

7. The clavulanic acid filament processing apparatus according to claim 1, wherein: The stirring structure has three, the stirring structure comprises a stirring motor (500), a stirring rod (501) is installed on the output end of the stirring motor (500), and the three stirring rods (501) are respectively located in the inside of the corresponding processing tank (100), drying bin (105) and acidolysis receiving tank (300).

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