Crushing device of full-automatic liquid-based cell pelleter

The fragmentation device, which incorporates a three-dimensional moving component and a power diversion structure, solves the problem of adhesion and accumulation of viscous cell samples in traditional fragmentation devices, achieving efficient cell dispersion and meeting the requirements for high-precision slide preparation.

CN223992738UActive Publication Date: 2026-03-13XIAOGAN BEIDOU XINGHANG BIOTECHNOLOGY CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-28
Publication Date
2026-03-13

AI Technical Summary

Technical Problem

Traditional cell disruption devices are prone to causing samples to stick to the blades or accumulate at the bottom of the container when processing viscous cell samples, and the linear disruption action cannot meet the requirements for high-precision cell dispersion.

Method used

The device employs a three-dimensional moving component and a power diversion structure, including a first moving part, a second moving part, and a third moving part. Combined with a driving component and a driven component, it achieves multi-dimensional coordinated crushing of the crushing blades. The driving component drives the first crushing blade to rotate, and the driven component realizes the vibration of the second crushing blade, thus forming a multi-dimensional crushing action.

Benefits of technology

It improves the fragmentation effect, ensures uniform dispersion of cell samples, avoids equipment blockage caused by adhesion and accumulation, and meets the requirements of high-precision slide preparation.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223992738U_ABST
    Figure CN223992738U_ABST
Patent Text Reader

Abstract

The utility model provides a crushing device of a full-automatic liquid-based cell pelleter, which comprises a bottom plate, walking wheels are arranged on the lower portion of the bottom plate, a push rod, a placing box and a processing box are arranged on the bottom plate, a sealing door is rotatably connected onto the processing box, an extension plate is fixedly connected onto the inner wall of the processing box, and the extension plate is fixedly connected onto the inner wall of the placing box. A first moving part is arranged on the extension plate, a cross rod is arranged on the first moving part, a second moving part is arranged on the cross rod, a mounting plate is arranged on the second moving part, and a third moving part is arranged on the mounting plate. According to the crushing device of the full-automatic liquid-based cell pelleter, provided by the utility model, the three-dimensional moving assembly consisting of the first moving part, the second moving part, the third moving part and the like ensures that samples in all containers placed in the base can be accurately positioned and treated; and the driven assembly also drives the second crushing blade to vibrate up and down to assist in crushing, so that the crushing effect is improved.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] This utility model relates to the field of cell preparation technology, and in particular to a crushing device for a fully automatic liquid-based cell preparation machine. Background Technology

[0002] Liquid-based cell preparation technology is an important pretreatment step in medical testing, such as cervical cancer screening and pathological diagnosis. Its core lies in the efficient disruption and uniform dispersion of cell samples.

[0003] Traditional cell disruption devices often employ a single rotating blade or a fixed disruption structure, which presents the following problems: viscous cell samples tend to stick to the blade or accumulate at the bottom of the container during disruption, resulting in uneven processing or even equipment blockage; existing equipment often relies on linear disruption actions from a single power source, lacking a multi-dimensional collaborative disruption mechanism, and sometimes failing to meet the requirements for cell dispersion in high-precision slide preparation.

[0004] Therefore, it is necessary to provide a crushing device for a fully automated liquid-based cell preparation machine to solve the above-mentioned technical problems. Utility Model Content

[0005] This invention provides a crushing device for a fully automatic liquid-based cell preparation machine, which solves the problem that viscous cell samples tend to stick to the blades or accumulate at the bottom of the container during the crushing process, and that the linear crushing action cannot meet the cell dispersion requirements during the crushing process.

[0006] To solve the above-mentioned technical problems, this utility model provides a crushing device for a fully automatic liquid-based cell slide preparation machine, comprising: a base plate, with wheels on the lower part of the base plate, a push rod, a placement box, and a processing box on the base plate, a rotatably connected door on the processing box, an extension plate fixedly connected to the inner wall of the processing box, a first moving part on the extension plate, a crossbar on the first moving part, a second moving part on the crossbar, a mounting plate on the second moving part, a third moving part on the mounting plate, a lifting seat on the third moving part, a driving component at the middle position of the lifting seat, a first crushing blade fixedly connected to the output end of the driving component, driven components on both sides of the lifting seat, a second crushing blade fixedly connected to the driven components, and a placement base at the bottom of the processing box, with evenly distributed containers placed inside the placement base.

[0007] Preferably, the first moving part includes a first sliding rail, on which a first slider is slidably connected, and the crossbar is fixedly connected to the first slider; the second moving part includes a second sliding rail, on which a second slider is slidably connected, and the mounting plate is fixedly connected to the second slider; the third moving part includes a third sliding rail, on which a third slider is slidably connected, and the lifting seat is fixedly connected to the third slider.

[0008] Preferably, the drive assembly includes a motor mounting bracket, on which a drive motor is mounted, and at the output end of the drive motor is a drive shaft. The drive shaft passes through the lifting seat to its lower part and is rotatably connected thereto. The first crushing blade is fixedly connected to the end of the drive shaft, and a first bevel gear is fixedly connected to the drive shaft.

[0009] Preferably, the driven component includes a fixed base and a vibrating rod, a driven shaft is rotatably connected to the fixed base, and a second bevel gear and a cam are respectively fixedly connected to both ends of the driven shaft.

[0010] Preferably, the vibrating rod is slidably connected to both sides of the lifting seat, the lower end of the vibrating rod is fixedly connected to the second crushing blade, and the upper end of the vibrating rod corresponds to the cam.

[0011] Preferably, a spring is sleeved on the vibrating rod, and a limiting plate is provided at the upper end of the vibrating rod, with the limiting plate located on both sides of the cam.

[0012] Compared with related technologies, the crushing device of the fully automatic liquid-based cell preparation machine provided by this utility model has the following beneficial effects:

[0013] This utility model provides a crushing device for a fully automatic liquid-based cell preparation machine. The three-dimensional moving assembly, composed of a first moving part, a second moving part, and a third moving part, ensures that the samples in each container in the base can be accurately positioned and processed. While the driving component drives the first crushing blade to rotate, the driven component also drives the second crushing blade to vibrate up and down to assist in crushing and improve the crushing effect. Attached Figure Description

[0014] Figure 1 A schematic diagram of a preferred embodiment of the crushing device for a fully automatic liquid-based cell slide preparation machine provided by this utility model;

[0015] Figure 2 This is a schematic diagram of the internal structure of the processing box in this utility model;

[0016] Figure 3 This is a schematic diagram of the structure of the second and third moving parts in this utility model;

[0017] Figure 4 This is a schematic diagram of the drive component and the driven component in this utility model.

[0018] The following components are labeled in the diagram: 1. Base plate, 2. Traveling wheel, 3. Push rod, 4. Placement box, 5. Processing box, 6. Sealing door, 7. Extension plate, 8. First moving part, 81. First sliding rail, 82. First slider, 9. Crossbar, 10. Second moving part, 101. Second sliding rail, 102. Second slider, 11. Mounting plate, 12. Third moving part, 121. Third sliding rail, 122. Third slider, 13. Lifting seat, 14. Drive assembly, 141. Motor mounting bracket, 142. Drive motor, 143. Drive shaft, 144. First bevel gear, 15. First crushing blade, 16. Driven assembly, 161. Fixed seat, 162. Driven shaft, 163. Second bevel gear, 164. Cam, 165. Vibration rod, 166. Spring, 167. Limiting plate, 17. Second crushing blade, 18. Placement base, 19. Container. Detailed Implementation

[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0020] Please refer to the following: Figure 1 , Figure 2 , Figure 3 and Figure 4 ,in, Figure 1 A schematic diagram of a preferred embodiment of the crushing device for a fully automatic liquid-based cell slide preparation machine provided by this utility model;

[0021] Figure 2 This is a schematic diagram of the internal structure of the processing box in this utility model;

[0022] Figure 3 This is a schematic diagram of the structure of the second and third moving parts in this utility model;

[0023] Figure 4 This is a schematic diagram of the drive component and the driven component in this utility model.

[0024] A crushing device for a fully automatic liquid-based cell preparation machine includes: a base plate 1, with wheels 2 at the bottom of the base plate 1; a push rod 3, a placement box 4, and a processing box 5 on the base plate 1; a rotatably connected sealing door 6 on the processing box 5; an extension plate 7 fixedly connected to the inner wall of the processing box 5; a first moving part 8 on the extension plate 7; a crossbar 9 on the first moving part 8; a second moving part 10 on the crossbar 9; a mounting plate 11 on the second moving part 10; a third moving part 12 on the mounting plate 11; a lifting seat 13 on the third moving part 12; a drive assembly 14 at the middle position of the lifting seat 13; a first crushing blade 15 fixedly connected to the output end of the drive assembly 14; driven assemblies 16 on both sides of the lifting seat 13; second crushing blades 17 fixedly connected to the driven assemblies 16; and a placement base 18 at the bottom of the processing box 5, with evenly distributed containers 19 inside the placement base 18.

[0025] The container 19 is transferred from the placement box 4 to the placement base 18, and the sealing door 6 is closed. The first moving part 8, the crossbar 9, the second moving part 10, the mounting plate 11, the third moving part 12 and the lifting seat 13 move continuously. The samples in each container 19 placed in the placement base 18 are processed by the drive assembly 14, the first crushing blade 15, the driven assembly 16 and the second crushing blade 17.

[0026] The first moving part 8 includes a first sliding rail 81, on which a first slider 82 is slidably connected. The crossbar 9 is fixedly connected to the first slider 82. The second moving part 10 includes a second sliding rail 101, on which a second slider 102 is slidably connected. The mounting plate 11 is fixedly connected to the second slider 102. The third moving part 12 includes a third sliding rail 121, on which a third slider 122 is slidably connected. The lifting seat 13 is fixedly connected to the third slider 122.

[0027] The first moving part 8 adopts a combination structure of the first sliding rail 81 and the first slider 82, which allows the crossbar 9 to move flexibly in the horizontal direction. Together with the second sliding rail 101 and the second slider 102 of the second moving part 10, it realizes the two-dimensional position adjustment of the mounting plate 11 in the vertical plane. Combined with the lifting function of the third sliding rail 121 and the third slider 122 of the third moving part 12, a precise positioning system in three-dimensional space is formed, which effectively expands the working coverage of the crushing blade.

[0028] The drive assembly 14 includes a motor mounting bracket 141, on which a drive motor 142 is mounted. The output end of the drive motor 142 is provided with a drive shaft 143. The drive shaft 143 passes through the lifting seat 13 to its lower part and is rotatably connected to it. The first crushing blade 15 is fixedly connected to the end of the drive shaft 143. A first bevel gear 144 is fixedly connected to the drive shaft 143.

[0029] The drive assembly 14 drives the drive shaft 143 through the drive motor 142 to rotate the first crushing blade 15. At the same time, the first bevel gear 144 is used to achieve power diversion. While ensuring the main blade cuts efficiently, it provides a synchronous power source for the driven assemblies 16 on both sides, thereby improving crushing efficiency and uniformity.

[0030] The driven component 16 includes a fixed base 161 and a vibrating rod 165. A driven shaft 162 is rotatably connected to the fixed base 161. A second bevel gear 163 and a cam 164 are fixedly connected to both ends of the driven shaft 162, respectively.

[0031] The first bevel gear 144 and the second bevel gear 163 rotate synchronously with the driven shaft 162 when the drive motor 142 starts.

[0032] The vibrating rod 165 is slidably connected to both sides of the lifting seat 13, the lower end of the vibrating rod 165 is fixedly connected to the second crushing blade 17, and the upper end of the vibrating rod 165 corresponds to the cam 164.

[0033] The driven component 16 adopts a linkage mechanism between the cam 164 and the vibrating rod 165 to convert the rotational motion into regular up-and-down vibration, so that the second crushing blade 17 forms a reciprocating impact crushing action, effectively avoiding the blockage problem caused by cell sample adhesion or accumulation.

[0034] A spring 166 is sleeved on the vibrating rod 165, and a limiting plate 167 is provided at the upper end of the vibrating rod 165. The limiting plate 167 is located on both sides of the cam 164.

[0035] The limiting plate 167 at the end of the vibrating rod 165 and the spring 166 form a double limiting protection. Together with the buffer structure of the spring 166, they form an elastic vibration system, which can limit the vibration amplitude to ensure operational safety and maintain the stability of the vibration frequency through the elastic reset function, thus extending the service life of mechanical parts.

[0036] The working principle of the crushing device of the fully automatic liquid-based cell preparation machine provided by this utility model is as follows:

[0037] The container 19 is transferred from the placement box 4 to the placement base 18, and the sealing door 6 is closed. The first moving part 8, the crossbar 9, the second moving part 10, the mounting plate 11, the third moving part 12 and the lifting seat 13 move continuously. The samples in each container 19 placed in the placement base 18 are processed by the drive assembly 14, the first crushing blade 15, the driven assembly 16 and the second crushing blade 17.

[0038] Compared with related technologies, the crushing device of the fully automatic liquid-based cell preparation machine provided by this utility model has the following beneficial effects:

[0039] The three-dimensional moving assembly, consisting of the first moving part 8, the second moving part 10, and the third moving part 12, ensures that the samples in each container 19 in the base 18 can be accurately positioned and processed. While the driving assembly 14 drives the first crushing blade 15 to operate, the driven assembly 16 also drives the second crushing blade 17 to vibrate up and down to assist in crushing and improve the crushing effect.

[0040] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the content of this utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.

Claims

1. A crushing device of a fully automatic liquid-based cell preparation machine, characterized in that, Include: The bottom plate is provided with walking wheels in the lower part, and the push rod, the placing box and the processing box are arranged on the bottom plate, the closed door is rotatably connected to the processing box, the extension plate is fixedly connected to the inner wall of the processing box, the first moving part is arranged on the extension plate, the horizontal rod is arranged on the first moving part, the second moving part is arranged on the horizontal rod, the mounting plate is arranged on the second moving part, the third moving part is arranged on the mounting plate, the lifting seat is arranged on the third moving part, the drive assembly is arranged at the middle position of the lifting seat, the first crushing blade is fixedly connected to the output end of the drive assembly, the driven assembly is arranged at the both sides of the lifting seat, the second crushing blade is fixedly connected to the driven assembly, and the placing base is arranged at the bottom of the processing box.

2. The crushing device of a fully automatic liquid-based cell preparator according to claim 1, wherein The first moving part includes a first sliding rail, a first sliding block is slidably connected to the first sliding rail, the horizontal rod is fixedly connected to the first sliding block, the second moving part includes a second sliding rail, a second sliding block is slidably connected to the second sliding rail, the mounting plate is fixedly connected to the second sliding block, and the third moving part includes a third sliding rail, a third sliding block is slidably connected to the third sliding rail, and the lifting seat is fixedly connected to the third sliding block.

3. The crushing device of a fully automatic liquid-based cell preparator according to claim 1, wherein The drive assembly includes a motor mounting frame, a drive motor is arranged on the motor mounting frame, a drive shaft is arranged at the output end of the drive motor, the drive shaft penetrates the lifting seat and is rotatably connected to the lifting seat below, the first crushing blade is fixedly connected to the end of the drive shaft, and a first bevel gear is fixedly connected to the drive shaft.

4. The crushing device of a fully automatic liquid-based cell preparator according to claim 3, wherein The driven assembly includes a fixed seat and a vibration rod, a driven shaft is rotatably connected to the fixed seat, and a second bevel gear and a cam are fixedly connected to the both ends of the driven shaft.

5. The crushing device of a fully automatic liquid-based cell preparator according to claim 4, wherein The vibration rod is slidably connected to the both sides of the lifting seat, the lower end of the vibration rod is fixedly connected to the second crushing blade, and the upper end of the vibration rod corresponds to the cam.

6. The crushing device of a fully automatic liquid-based cell preparator according to claim 5, wherein The spring is sleeved on the vibration rod, the upper end of the vibration rod is provided with a limiting plate, and the limiting plate is located at the both sides of the cam.