Integrated liquid path unit box applied to blood component separation process
The integrated fluid circuit unit design simplifies the control process of blood component separation, reduces resource waste and operational difficulty, and achieves efficient utilization of blood resources.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-23
- Publication Date
- 2026-03-20
AI Technical Summary
Existing technologies for blood component separation suffer from problems such as complex control, the need for multiple pipelines leading to resource waste, and high operational difficulty.
An integrated fluid circuit unit box is designed, which divides the box body into two cavities by a partition. The partition is equipped with a passage groove, a switch groove, and a pressure measuring groove. Combined with pipeline connectors and control devices, the separation and control of blood components can be realized.
It simplifies the operation process, reduces the amount of blood circulating outside the body and residues, improves the utilization rate of blood resources, and reduces the difficulty and time cost of operation.
Smart Images
Figure CN224008791U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The application relates to an integrated liquid path unit box applied to a blood component separation process and belongs to the technical field of blood separation. BACKGROUND
[0002] The blood component separation process is relatively complex and includes blood collection and blood return stages, and the blood flows of various components in each stage are different. The single-path pipeline of the prior art can only allow one-component blood to flow in one direction, and has the following defects:
[0003] 1. The blood component separation process control mode is complex, and high technical requirements are put forward for the equipment. 2. A large number of pipelines are required, the extracorporeal blood circulation volume is increased, the blood residual volume is large, and blood resources are wasted. 3. The operation proficiency of the operator is required to be high due to the large number of pipelines.
[0004] To solve the above problems, an integrated liquid path unit box applied to a blood component separation process and a control mode thereof are provided. Practical new type content
[0005] The technical problem to be solved by the application is to overcome the defects of the prior art, provide an integrated liquid path unit box applied to a blood component separation process, and simplify the control process, reduce resource waste and reduce the operation difficulty.
[0006] The technical scheme adopted by the application to solve the existing problems is:
[0007] An integrated liquid path unit box applied to a blood component separation process comprises a unit box body, the unit box body is open at both ends, a partition plate is arranged in the middle, the partition plate divides the unit box body into two cavities, a plurality of passage grooves are arranged on the plane of the partition plate in one of the cavities, and the passage grooves are flow paths for blood.
[0008] A unit box upper cover is mounted at the opening of one end of the unit box body provided with the plurality of passage grooves, and the unit box upper cover is used for sealing the top of the passage grooves.
[0009] A bottom soft film is mounted at the opening of the other end of the unit box body and used for sealing the opening of the other end of the unit box body.
[0010] Preferably, a plurality of passage holes are arranged on the partition plate, the passage holes are located in the passage grooves, and the passage holes communicate the two cavities of the unit box body.
[0011] The side wall of the passage groove protrudes from the plane of the partition plate.
[0012] Preferably, a plurality of through-holes are arranged on the plane of the partition plate in the other cavity of the unit box, including a first through-hole, a second through-hole, a third through-hole, a fourth through-hole, a fifth through-hole, a sixth through-hole, a seventh through-hole, an eighth through-hole, a ninth through-hole, and a tenth through-hole, the side walls of the first through-hole, the second through-hole, the third through-hole, the fourth through-hole, the fifth through-hole, the sixth through-hole, the seventh through-hole, the eighth through-hole, the ninth through-hole, and the tenth through-hole protrude from the plane of the partition plate.
[0013] A plurality of pressure-measuring circular grooves are arranged on the plane of the partition plate in the other cavity of the unit box, including a first pressure-measuring circular groove, a second pressure-measuring circular groove, a third pressure-measuring circular groove, and a fourth pressure-measuring circular groove, the side walls of the first pressure-measuring circular groove, the second pressure-measuring circular groove, the third pressure-measuring circular groove, and the fourth pressure-measuring circular groove protrude from the plane of the partition plate.
[0014] Preferably, the first through-hole, the second through-hole, the third through-hole, the fourth through-hole, the fifth through-hole, the sixth through-hole, the seventh through-hole, the eighth through-hole, the ninth through-hole, the tenth through-hole, the first pressure-measuring circular groove, the second pressure-measuring circular groove, the third pressure-measuring circular groove, and the fourth pressure-measuring circular groove are respectively sealed by the bottom soft film to form cavities.
[0015] Preferably, a plurality of pipeline joints are arranged on the two sides of the unit box and communicate with the through-way grooves, including a first pipeline joint, a second pipeline joint, a third pipeline joint, a fourth pipeline joint, a fifth pipeline joint, a sixth pipeline joint, a seventh pipeline joint, an eighth pipeline joint, a ninth pipeline joint, and a tenth pipeline joint, the first pipeline joint, the second pipeline joint, the third pipeline joint, the fourth pipeline joint, the fifth pipeline joint, the sixth pipeline joint, the seventh pipeline joint, the eighth pipeline joint, the ninth pipeline joint, and the tenth pipeline joint are used for the inflow or outflow of blood.
[0016] Preferably, the through-holes are isolated into a plurality of groups by the through-holes and the pressure-measuring circular grooves, two through-holes are contained in each through-hole, and three through-holes are contained in each pressure-measuring circular groove.
[0017] The through-holes can be connected to a control device, and the flow of blood in the through-way grooves is controlled by controlling the opening and closing of the two through-holes contained in the through-holes.
[0018] The pressure-measuring circular grooves can be connected to a pressure sensor to detect the pressure of the blood flowing through each channel.
[0019] Preferably, a plurality of sealing grooves are arranged on the upper cover of the unit box, the sealing grooves are recessed from the plane of the upper cover of the unit box, and the shapes of the sealing grooves are consistent with the shapes of the side walls of the through-way grooves.
[0020] Preferably, the unit box is transparent plastic material, and the flow state of each blood component in the unit box can be observed.
[0021] Compared with the prior art, the application has the beneficial effects:
[0022] The application reduces the complexity of multiple independent pipelines, making the operation more simple and intuitive.
[0023] The amount of extracorporeal blood circulation and the amount of blood residue are reduced, and the utilization rate of blood resources is improved.
[0024] The operation steps are reduced, the skill requirement for the operator is reduced, the time is saved, and the work efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS
[0025] Figure 1 FIG. 1 is a structural schematic diagram of an integrated liquid path unit box applied to a blood component separation process according to the application;
[0026] Figure 2 FIG. 2 is a top view of a unit box body of an integrated liquid path unit box applied to a blood component separation process according to the application;
[0027] Figure 3 FIG. 3 is a bottom view of a unit box body of an integrated liquid path unit box applied to a blood component separation process according to the application;
[0028] Figure 4 FIG. 4 is a front view of a unit box upper cover of an integrated liquid path unit box applied to a blood component separation process according to the application.
[0029] In the drawings:
[0030] 1, unit box body, 101, passage groove, 102, passage hole, 103, partition plate, 104, first on-off circular groove, 105, second on-off circular groove, 106, third on-off circular groove, 107, fourth on-off circular groove, 108, fifth on-off circular groove, 109, sixth on-off circular groove, 110, seventh on-off circular groove, 111, eighth on-off circular groove, 112, ninth on-off circular groove, 113, tenth on-off circular groove, 114, first pressure measurement circular groove, 115, second pressure measurement circular groove, 116, third pressure measurement circular groove, 117, fourth pressure measurement circular groove, 118, first pipeline joint, 119, second pipeline joint, 120, third pipeline joint, 121, fourth pipeline joint, 122, fifth pipeline joint, 123, sixth pipeline joint, 124, seventh pipeline joint, 125, eighth pipeline joint, 126, ninth pipeline joint, 127, tenth pipeline joint, 2, unit box upper cover, 21, sealing groove, 3, bottom soft film. DETAILED DESCRIPTION
[0031] As used in the specification and claims, certain terminology is used to describe certain features. Those of ordinary skill in the art will understand that a hardware manufacturer can use different names to refer to the same feature. The specification and claims should not be construed to be limited by the names used to refer to the features. Rather, the specification and claims should be construed by the language of the features themselves. As used throughout the specification and claims, "comprising" is to be read as "comprising, without limitation." "Approximately" means within an acceptable error range for the corresponding function, which will vary from implementation to implementation.
[0032] In the description of the present application, it is to be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "back", "left", "right", "horizontal", etc. are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application.
[0033] In the present application, unless specifically defined and limited otherwise, the terms "mounting", "connecting", "connecting", "fixing" and the like should be interpreted broadly, for example, it can be fixed connection, or detachable connection, or integrally connected; it can be mechanical connection, or electrical connection; it can be directly connected, or indirectly connected through intermediate medium, or internal communication of two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.
[0034] As shown in Figures 1-4 An integrated liquid path unit cartridge applied to a blood component separation process includes a cartridge body 1, which is open at both ends and has a partition plate 103 in the middle, separating the cartridge body 1 into two cavities. A plurality of passage grooves 101 are arranged on the plane of the partition plate 103 in one of the cavities, each passage groove 101 being independent of the others, and the passage grooves 101 being flow paths for blood.
[0035] A plurality of passage holes 102 are arranged on the partition plate 103, the passage holes 102 being located in the passage grooves 101 and connecting the two cavities of the cartridge body 1. The side walls of the passage grooves 101 protrude from the plane of the partition plate 103.
[0036] A bottom soft film 3 is mounted at the opening of the other end of the cartridge body 1, and the bottom soft film 3 is a flexible plastic film.
[0037] A plurality of on-off circular grooves are arranged on the plane of the partition plate 103 in the other cavity of the unit box 1, including a first on-off circular groove 104, a second on-off circular groove 105, a third on-off circular groove 106, a fourth on-off circular groove 107, a fifth on-off circular groove 108, a sixth on-off circular groove 109, a seventh on-off circular groove 110, an eighth on-off circular groove 111, a ninth on-off circular groove 112, and a tenth on-off circular groove 113, the side walls of which protrude from the plane of the partition plate 103.
[0038] A plurality of pressure measuring circular grooves are also arranged on the plane of the partition plate 103 in the other cavity of the unit box 1, including a first pressure measuring circular groove 114, a second pressure measuring circular groove 115, a third pressure measuring circular groove 116, and a fourth pressure measuring circular groove 117, the side walls of which protrude from the plane of the partition plate 103.
[0039] The bottom soft film 3 is welded to one end of the unit box 1 with on-off circular grooves and pressure measuring circular grooves, to seal the opening of the unit box 1 and the openings of the on-off circular grooves and pressure measuring circular grooves.
[0040] The first on-off circular groove 104, the second on-off circular groove 105, the third on-off circular groove 106, the fourth on-off circular groove 107, the fifth on-off circular groove 108, the sixth on-off circular groove 109, the seventh on-off circular groove 110, the eighth on-off circular groove 111, the ninth on-off circular groove 112, the tenth on-off circular groove 113, the first pressure measuring circular groove 114, the second pressure measuring circular groove 115, the third pressure measuring circular groove 116, and the fourth pressure measuring circular groove 117 are respectively sealed with the bottom soft film 3 to form cavities.
[0041] The on-off circular grooves and pressure measuring circular grooves separate the through holes 102 into a plurality of groups, each on-off circular groove containing two through holes 102, and each pressure measuring circular groove containing three through holes 102. The on-off circular grooves can be connected to control devices, to control the flow path of blood in the through groove 101 by controlling the on or off of the two through holes 102 contained in the on-off circular grooves. The pressure measuring circular grooves can be connected to pressure sensors to detect the pressure of blood flowing through each channel.
[0042] The two sides of the unit box 1 are also provided with several pipeline joints in communication with the passage slots 101, which include a first pipeline joint 118, a second pipeline joint 119, a third pipeline joint 120, a fourth pipeline joint 121, a fifth pipeline joint 122, a sixth pipeline joint 123, a seventh pipeline joint 124, an eighth pipeline joint 125, a ninth pipeline joint 126, and a tenth pipeline joint 127, which are used for the inflow or outflow of blood.
[0043] The end opening of the unit box 1 provided with several passage slots 101 is mounted with a unit box upper cover 2, which is provided with several sealing grooves 21 recessed in the plane of the unit box upper cover 2, the shape of the sealing grooves 21 being consistent with the shape of the side walls of the passage slots 101, and the unit box upper cover 2 being used to seal the top of the passage slots 101.
[0044] The unit box can selectively guide the blood flow to different paths to achieve the separation or return of various blood components.
[0045] In combination Figure 2 and Figure 3 As shown in the figure, during normal operation, if blood is to be flowed in from the first pipeline joint 118 and out from the tenth pipeline joint 127, the working process is as follows: blood flows in from the first pipeline joint 118, enters the passage slot 101 at the first pipeline joint 118, enters the seventh on-off circular groove 110 from the passage hole 102 in the passage slot 101 at the first pipeline joint 118, enters the corresponding passage slot 101 at the seventh on-off circular groove 110 from the other passage hole 102 in the seventh on-off circular groove 110, and then enters the second pressure measuring circular groove 115 from the other passage hole 102 in the passage slot 101 at this position, enters the passage slot 101 in communication with the tenth pipeline joint 127 from the passage hole 102 in the second pressure measuring circular groove 115 close to the tenth pipeline joint 127, and finally blood flows out from the tenth pipeline joint 127.
[0046] In this working process, the control device connected with the first on-off circular groove 104, the second on-off circular groove 105, the third on-off circular groove 106, the fourth on-off circular groove 107, the fifth on-off circular groove 108, the sixth on-off circular groove 109, the eighth on-off circular groove 111, the ninth on-off circular groove 112 and the tenth on-off circular groove 113 presses the bottom soft film 3 at the corresponding first on-off circular groove 104, the second on-off circular groove 105, the third on-off circular groove 106, the fourth on-off circular groove 107, the fifth on-off circular groove 108, the sixth on-off circular groove 109, the eighth on-off circular groove 111, the ninth on-off circular groove 112 and the tenth on-off circular groove 113, and blocks the through hole 102 in the first on-off circular groove 104, the second on-off circular groove 105, the third on-off circular groove 106, the fourth on-off circular groove 107, the fifth on-off circular groove 108, the sixth on-off circular groove 109, the eighth on-off circular groove 111, the ninth on-off circular groove 112 and the tenth on-off circular groove 113, so that the blood does not flow through other paths, and the blood flow path can be observed by the unit box 1. The pressure sensor connected with the second pressure measuring circular groove 115 monitors the pressure in the blood flow process at any time to prevent the unit box 1 from being damaged by excessive pressure.
[0047] The embodiments of the present application are described in detail above with reference to the drawings, but the present application is not limited to the above-described embodiments, and various changes can be made within the knowledge of those skilled in the art without departing from the purpose of the present application.
Claims
1. An integrated liquid circuit unit box for use in blood component separation processes, characterized in that: Includes a unit box (1), the unit box (1) is open at both ends and a partition (103) is provided in the middle. The partition (103) divides the unit box (1) into two cavities. Several passage grooves (101) are provided on the plane of the partition (103) in one of the cavities. The passage grooves (101) are for blood flow paths. A unit box body (1) with several passage slots (101) is provided with a unit box cover (2) installed at one end of the opening. The unit box cover (2) is used to seal the top of the passage slots (101). A bottom soft film (3) is installed at the other end opening of the unit box (1) to seal the other end opening of the unit box (1).
2. The integrated liquid circuit unit box for blood component separation process according to claim 1, characterized in that: The partition (103) is provided with several passage holes (102), the passage holes (102) are located in the passage groove (101), and the passage holes (102) connect the two cavities of the unit box (1); The sidewall of the passage groove (101) protrudes from the plane of the partition (103).
3. An integrated liquid circuit unit box for blood component separation process according to claim 2, characterized in that: Several through-and-off circular grooves are provided on the plane of the partition (103) located in another cavity of the unit box (1). The through-and-off circular grooves include a first through-and-off circular groove (104), a second through-and-off circular groove (105), a third through-and-off circular groove (106), a fourth through-and-off circular groove (107), a fifth through-and-off circular groove (108), a sixth through-and-off circular groove (109), a seventh through-and-off circular groove (110), an eighth through-and-off circular groove (111), and a ninth through-and-off circular groove (112). And the tenth through-cut circular groove (113), the sidewalls of the first through-cut circular groove (104), the second through-cut circular groove (105), the third through-cut circular groove (106), the fourth through-cut circular groove (107), the fifth through-cut circular groove (108), the sixth through-cut circular groove (109), the seventh through-cut circular groove (110), the eighth through-cut circular groove (111), the ninth through-cut circular groove (112) and the tenth through-cut circular groove (113) protrude from the plane of the partition (103); Several pressure measuring grooves are also provided on the plane of the partition (103) located in another cavity of the unit box (1). The pressure measuring grooves include a first pressure measuring groove (114), a second pressure measuring groove (115), a third pressure measuring groove (116), and a fourth pressure measuring groove (117). The sidewalls of the first pressure measuring groove (114), the second pressure measuring groove (115), the third pressure measuring groove (116), and the fourth pressure measuring groove (117) protrude from the plane of the partition (103).
4. An integrated liquid circuit unit box for blood component separation process according to claim 3, characterized in that: The first open / close circular groove (104), the second open / close circular groove (105), the third open / close circular groove (106), the fourth open / close circular groove (107), the fifth open / close circular groove (108), the sixth open / close circular groove (109), the seventh open / close circular groove (110), the eighth open / close circular groove (111), the ninth open / close circular groove (112), the tenth open / close circular groove (113), the first pressure measuring circular groove (114), the second pressure measuring circular groove (115), the third pressure measuring circular groove (116), and the fourth pressure measuring circular groove (117) are sealed with the bottom soft membrane (3) to form cavities.
5. An integrated liquid circuit unit box for blood component separation process according to claim 1, characterized in that: The unit box (1) is also provided with several pipe joints on both sides that communicate with the passage groove (101). The pipe joints include a first pipe joint (118), a second pipe joint (119), a third pipe joint (120), a fourth pipe joint (121), a fifth pipe joint (122), a sixth pipe joint (123), a seventh pipe joint (124), an eighth pipe joint (125), a ninth pipe joint (126), and a tenth pipe joint (127). The first pipe joint (118), the second pipe joint (119), the third pipe joint (120), the fourth pipe joint (121), the fifth pipe joint (122), the sixth pipe joint (123), the seventh pipe joint (124), the eighth pipe joint (125), the ninth pipe joint (126), and the tenth pipe joint (127) are used for the inflow or outflow of blood.
6. An integrated liquid circuit unit box for blood component separation process according to claim 3, characterized in that: The on / off groove and the pressure measuring groove isolate the passage hole (102) into several groups. Each on / off groove contains two passage holes (102), and each pressure measuring groove contains three passage holes (102). The on / off circular groove can be connected to a control device, which controls the flow of blood in the passage groove (101) by controlling the opening and closing of the two passage holes (102) contained in the on / off circular groove; The pressure measuring groove can be connected to a pressure sensor to detect the pressure of blood flowing through each channel.
7. An integrated liquid circuit unit box for blood component separation process according to claim 1, characterized in that: The unit box cover (2) is provided with several sealing grooves (21), the sealing grooves (21) are recessed in the plane of the unit box cover (2), and the shape of the sealing grooves (21) is consistent with the side wall shape of the passage groove (101).
8. An integrated liquid circuit unit box for blood component separation process according to claim 1, characterized in that: The unit box is made of transparent plastic, allowing observation of the flow of various blood components within the unit box.