Granulation device for pharmaceutical production

Abstract

The utility model relates to the field of granulating devices, and discloses a granulating device for pharmaceutical production, which comprises a base, the outer wall of the base is fixedly connected with a granule guide plate, the inside of the base is fixedly connected with a plurality of fixing strips, the top end of the base is slidably connected with a filter screen, the bottom end of the filter screen is provided with a plurality of sliding grooves, and the bottom end of the filter screen is fixedly connected with the granule guide plate. A first connecting ring is fixedly connected to the top of the filter screen, a first fixing ring is slidably connected to the outer wall of the first connecting ring, a rotating assembly is arranged on one side of the first fixing ring, a second fixing ring is slidably connected to the outer wall of the first connecting ring, and a connecting assembly is arranged on one side of the second fixing ring. According to the utility model, the filter screen part is rotated firstly, then the filter screen is lifted upwards to be disassembled, and then the nut is rotated to unlock the connecting ring I and the connecting ring II, so that the effect of easily disassembling the equipment is achieved, and the problem that the equipment can be disassembled only through complicated operation is avoided; therefore, the convenience of the granulating device for pharmaceutical production is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of granulating device, especially to a granulating device for medicine production. BACKGROUND

[0002] The granulating device in medicine production is the equipment that makes medicine powder or other raw materials into particles with specific shape, size and granularity distribution, and it is very important in medicine production. It can improve material fluidity, solve the problems of conveying, metering and filling caused by poor flowability of raw powder, prevent dust flying, reduce medicine waste and environmental pollution, protect the health of operators, improve the compressibility of medicine, avoid problems such as cracking and loose tablets during tabletting, optimize the dissolution performance of medicine, improve the dissolution rate and bioavailability of poorly soluble medicine, facilitate uniform mixing of medicine, and ensure the consistency of the content of each component of medicine, so as to comprehensively improve the production efficiency and product quality of medicine.

[0003] The working principles of existing granulating devices for medicine production are different. In a wet granulator, the stirring wet granulator mixes, agglomerates and cuts the medicine powder and binder into uniform particles in a closed container by means of stirring paddle and cutting knife. The fluidized bed wet granulator uses airflow to fluidize the powder, sprays the binder and dries the particles with hot air. In a dry granulator, the roll-pressing dry granulator is to press the powder into tablets between relatively rotating pressure rollers and then break the tablets into particles. The heavy-pressing dry granulator is to press the powder into blocks in a mold, take out the blocks and then process the blocks into particles. The spray granulator sprays medicine solution or suspension into droplets, contacts the droplets with hot air, evaporates the solvent and forms particles. The centrifugal granulator makes the powder move in a rotating container by centrifugal force and agglomerate into particles under the action of binder. The one-step granulator completes the whole process of mixing medicine powder and excipient, spraying binder, granulating and drying with hot air in a closed container.

[0004] In the medicine production process, the granulating device is a very critical link, which directly affects the quality of medicine. However, the existing granulating device has a obvious disadvantage in actual application. After each granulation operation is completed, medicine particles and impurities are left in the equipment. According to the strict hygiene standards of medicine production, the equipment needs to be cleaned in time and thoroughly. However, the current granulating device needs to be disassembled for cleaning, which is quite complex in operation process. It not only needs to use various professional tools, but also needs to disassemble each part in a specific order and with great care. Any carelessness may damage the equipment. This not only consumes a lot of time and labor, but also seriously affects the production efficiency, causes the equipment to be unable to be put into use for a long time, and greatly reduces the convenience of the granulating device for medicine production, which brings many troubles to medicine production enterprises. SUMMARY

[0005] In order to make up for the above shortcomings, the utility model provides a granulating device for medicine production, aims at improving the problem that complicated operation is needed to disassemble the equipment to carry out cleaning work in the equipment use process.

[0006] In order to achieve the above object, the utility model adopts the following technical scheme: a granulating device for medicine production, including base, the base outer wall is fixedly connected with the guide particle board, a plurality of fixed strips are fixedly connected in the base, the base top is slidably connected with the filter screen, a plurality of sliding grooves are formed in the filter screen bottom, the filter screen top is fixedly connected with connecting ring no.

[0007] The connecting assembly includes a connecting block, a threaded column and a nut, one side of the connecting block is fixedly connected to one side of the fixed ring no.

[0008] As a further description of the above technical scheme:

[0009] The rotating assembly includes a connecting strip no.

[0010] As a further description of the above technical scheme:

[0011] The granulating assembly includes an extrusion blade, a drive column and a stirring blade, one side of the extrusion blade is rotatably connected to the top of the fixed disc, the outer wall of the drive column is rotatably connected to the inside of the fixed disc, the inner wall of the stirring blade is fixedly connected to one end of the drive column, and the output end of the motor no.

[0012] As a further description of the above technical scheme:

[0013] The drive assembly includes a drive gear, a driving gear and a motor no.

[0014] As a further description of the above technical scheme:

[0015] The plurality of fixed pins are slidably connected inside the extension cylinder, and the outer wall of each fixed pin is fixedly connected with a limiting plate.

[0016] As a further description of the above technical solution:

[0017] The plurality of springs are arranged inside the extension cylinder, one end of each spring is fixedly connected inside the extension cylinder, and the other end of each spring is fixedly connected to one end of the fixed pin.

[0018] As a further description of the above technical solution:

[0019] The top end of the extension cylinder is slidably connected with a sealing cover, and the top of the sealing cover is fixedly connected with a plurality of handles.

[0020] As a further description of the above technical solution:

[0021] The top of the sealing cover is fixedly connected with a feeding pipe, and the handles are fixedly connected to the top of the sealing cover in a symmetrical array.

[0022] The utility model has the following beneficial effects:

[0023] 1、the utility model discloses, first rotate filter screen part makes fixed strip from the inside of sliding groove and comes off, and then filters the screen and can be taken off to the filter screen, then rotates the nut and makes it from the threaded column and comes off, then rotates the threaded column to the other side and makes that connecting ring no. 1 and connecting ring no. 2 are unlocked, then lifts the extension cylinder and makes that filter screen part and extension cylinder part are unlocked, to reach the effect that the equipment can be easily disassembled to clean the equipment working part, avoid the problem that in the equipment use process, need complicated operation to disassemble the equipment to clean the work, thereby improve the convenience of the granulating device for medicine production.

[0024] 2、the utility model discloses, first hold two handles and take up the sealing cover upwards, to reach the effect that in the equipment use process, can block the foreign matter and enter the equipment interior and influence equipment operation, avoid the problem that in the equipment use process, the operator needs to prevent the foreign matter and enter the equipment interior and influence internal machinery operation, thereby improve the safety of the granulating device for medicine production. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1 A perspective view of the granulating device for medicine production is provided for the utility model;

[0026] Figure 2 A bottom seat internal structure schematic view of the granulating device for medicine production is provided for the utility model;

[0027] Figure 3 A fixed ring one structure schematic view of a granulating device for medicine production is provided for the utility model;

[0028] Figure 4 A sealing cover internal structure schematic view of a granulating device for medicine production is provided for the utility model;

[0029] Figure 5 For Figure 4 A local amplification structure schematic view at middle A.

[0030] Legend:

[0031] 1, base; 2, guide grain board; 3, fixed strip; 4, sliding groove; 5, filter screen; 6, connecting ring one; 7, fixed ring one; 8, connecting strip one; 9, rotating shaft; 10, connecting strip two; 11, fixed ring two; 12, connecting block; 13, threaded column; 14, nut; 15, extension cylinder; 16, connecting ring two; 17, fixed disc; 18, extrusion blade; 19, drive column; 20, stirring blade; 21, motor one; 22, drive gear; 23, driving gear; 24, motor two; 25, fixed pin; 26, limit plate; 27, spring; 28, sealing cover; 29, handle; 30, inlet pipe. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0033] Refer to Figures 1-3The utility model provides a kind of granulator for medicine production, including base 1, the outer wall of base 1 is fixedly connected with guide grain plate 2, for guiding out good medicine particle, a plurality of fixed strips 3 are fixedly connected in the inside of base 1, for fixing filter screen 5, the top of base 1 is slidably connected with filter screen 5, for making medicine particle, a plurality of sliding grooves 4 are arranged in the bottom of filter screen 5, for accommodating fixed strip 3, connecting ring one 6 is fixedly connected with the top of filter screen 5, the outer wall of connecting ring one 6 is slidably connected with fixed ring one 7, for connecting filter screen 5 and extension cylinder 15, rotating assembly is arranged on one side of fixed ring one 7, connecting ring two 11 is slidably connected with the outer wall of connecting ring one 6, for connecting filter screen 5 and extension cylinder 15, connecting assembly is arranged on one side of connecting ring two 11, extension cylinder 15 is slidably connected with the inner wall of connecting ring two 11, for extending equipment height, connecting ring two 16 is fixedly connected with the bottom of extension cylinder 15, the inside of base 1 is fixedly connected with fixed disc 17, for fixing equipment used for internal processing, granulating assembly is arranged on the top of fixed disc 17, motor one 21 is fixedly connected with the bottom of fixed disc 17, for driving stirring blade 20, drive assembly is arranged on the bottom of fixed disc 17;

[0034] Connecting assembly includes connecting block 12, threaded column 13 and nut 14, connecting block 12 is fixedly connected on one side of connecting ring two 11, for connecting threaded column 13, threaded column 13 is rotatably connected in one end in connecting block 12, for connecting fixed ring one 7 and connecting ring two 11, the inner wall of nut 14 is rotatably connected on the outer wall of threaded column 13, for fixing fixed ring one 7 and connecting ring two 11, rotating assembly includes connecting strip one 8, rotating shaft 9 and connecting strip two 10, connecting strip one 8 is fixedly connected in one end in fixed ring one 7, the outer wall of rotating shaft 9 is rotatably connected in one end in connecting strip one 8, for providing rotating condition for fixed ring one 7 and connecting ring two 11, connecting strip two 10 is rotatably connected in one end on the outer wall of rotating shaft 9, and is fixedly connected in one end in connecting ring two 11, and granulating assembly includes extrusion blade 18, drive column 19 and stirring blade 20, the one side of extrusion blade 18 is rotatably connected on the top of fixed disc 17, for extruding medicine powder to form medicine particle, the outer wall of drive column 19 is rotatably connected in the inside of fixed disc 17, for driving stirring blade 20 to rotate, the inner wall of stirring blade 20 is fixedly connected in one end in drive column 19, for breaking medicine powder, motor one 21 output end is connected with one end in drive column 19, and drive assembly includes drive gear 22, driving gear 23 and motor two 24, the one side of drive gear 22 is fixedly connected in one side of extrusion blade 18, for driving extrusion blade 18, the one end of driving gear 23 is fixedly connected on the output end of motor two 24, for driving drive gear 22, and the outer wall of motor two 24 is fixedly connected in the inside of base 1, for providing power for extrusion blade 18 rotation.

[0035] Specifically, during the cleaning and maintenance of the device, the filter screen 5 and the extension cylinder 15 are involved in the disassembly step. First, hold the filter screen 5 with both hands and slowly rotate it in a clockwise direction. As the rotation continues, the fixed bar 3 will gradually come out of the innermost part of the sliding groove 4. After the fixed bar 3 is completely separated from the sliding groove 4, the filter screen 5 can be lifted upwards. In this way, the filter screen 5 can be successfully removed from the device. Then, rotate the nut 14 along the thread of the threaded column 13, and gradually remove it from the threaded column 13. After the nut 14 is completely removed, continue to rotate the threaded column 13 until it is turned to the other side. At this time, the connection ring one 6 and the connection ring two 16 are successfully unlocked. Finally, lift the extension cylinder 15 with both hands. With the upward force, the filter screen 5 part and the extension cylinder 15 part are successfully unlocked, completing a series of complex disassembly operations.

[0036] Referring to Figure 4 and Figure 5 , the extension cylinder 15 is slidably connected with a plurality of fixed pins 25 inside for fixing the sealing cover 28. The outer wall of each fixed pin 25 is fixedly connected with a limiting plate 26 to limit the movement range of the fixed pin 25. The extension cylinder 15 is provided with a plurality of springs 27 inside to provide elastic force for the fixed pin 25. One end of each spring 27 is fixedly connected inside the extension cylinder 15, and the other end of each spring 27 is fixedly connected to one end of the fixed pin 25. The extension cylinder 15 is slidably connected with the sealing cover 28 at the top end to prevent other objects from entering the inside of the device. The sealing cover 28 is fixedly connected with a plurality of handles 29 at the top for disassembling the sealing cover 28. The sealing cover 28 is fixedly connected with an inlet pipe 30 at the top for introducing powder. The handles 29 are fixedly connected in a symmetrical array on the top of the sealing cover 28.

[0037] Specifically, when the internal machinery of the device needs to be repaired, first hold the two handles 29 on the top of the sealing cover 28, then use the arm strength to slowly and smoothly lift the sealing cover 28 upwards. During this process, a certain resistance will be felt, because the fixed pin 25 tightly plays a fixing role. As the sealing cover 28 is gradually lifted, the fixed pin 25 is extruded and begins to slowly retract into the extension cylinder 15. When it is determined that the fixed pin 25 has completely retracted into the extension cylinder 15, it means that the sealing cover 28 has been successfully unlocked. At this time, continue to increase the force on the hands and steadily lift the sealing cover 28. With the successful removal of the sealing cover 28, the top of the device is suddenly opened, revealing the complex internal mechanical structure, and fully preparing for the subsequent repair work of the internal machinery.

[0038] Working principle: in the process of using the medicine production granulating device, the inside of the equipment needs to be cleaned before use, first hold two handles 29 to lift the sealing cover 28 upwards, so as to extrude the fixed pin 25 and make it retract into the inside of the extension cylinder 15, then unlock the sealing cover 28, and continue to lift the sealing cover 28, then open the top of the equipment, then rotate the filter screen 5 part to make the fixed strip 3 from the inside of the sliding groove 4, then lift the filter screen 5 upwards to disassemble the filter screen 5, then rotate the nut 14 to make it from the threaded column 13, then rotate the threaded column 13 to the other side to make the connecting ring one 6 and the connecting ring two 16 unlock, then lift the extension cylinder 15 to make the filter screen 5 part and the extension cylinder 15 part unlock, thus the equipment is completely disassembled, and the cleaning work of the equipment can be started, when the cleaning is completed, the equipment is assembled, at the same time, the motor one 21 and the motor two 24 are started, so that the extrusion blade 18 and the stirring blade 20 start to rotate, then the medicine powder is poured into the inside of the equipment through the inlet pipe 30, the medicine particles generated under the extrusion of the extrusion blade 18 will enter the guide plate 2, and under the design of the inclined plate of the guide plate 2, the medicine particles are guided into the collecting equipment below.

[0039] Finally, it should be pointed out that: the above only for the preferred embodiments of the utility model, and does not limit the utility model, although the utility model is described in detail with reference to the foregoing embodiments, for the person skilled in the art, it still can modify the technical scheme recorded in the foregoing each embodiment, or make equivalent replacement to part of technical features, any modification, equivalent replacement, improvement etc. made within the spirit and principle of the utility model, should be contained in the protection scope of the utility model.

Claims

1. A granulation device for pharmaceutical production, comprising a base (1), characterized in that: A particle guide plate (2) is fixedly connected to the outer wall of the base (1). Multiple fixing strips (3) are fixedly connected inside the base (1). A filter screen (5) is slidably connected to the top of the base (1). Multiple sliding grooves (4) are opened at the bottom of the filter screen (5). A connecting ring (6) is fixedly connected to the top of the filter screen (5). A fixing ring (7) is slidably connected to the outer wall of the connecting ring (6). A rotating component is provided on one side of the fixing ring (7). The outer wall of the connecting ring (6) is slidably connected. A fixing ring two (11) is connected, and a connecting component is provided on one side of the fixing ring two (11). An extension cylinder (15) is slidably connected to the inner wall of the fixing ring two (11). A connecting ring two (16) is fixedly connected to the bottom of the extension cylinder (15). A fixing disk (17) is fixedly connected inside the base (1). A granulation component is provided on the top of the fixing disk (17). A motor one (21) is fixedly connected to the bottom of the fixing disk (17). A driving component is provided at the bottom of the fixing disk (17). The connecting assembly includes a connecting block (12), a threaded post (13), and a nut (14). One side of the connecting block (12) is fixedly connected to one side of the fixing ring (11). One end of the threaded post (13) is rotatably connected to the inside of the connecting block (12). The inner wall of the nut (14) is rotatably connected to the outer wall of the threaded post (13).

2. The granulation apparatus for pharmaceutical production according to claim 1, characterized in that: The rotating assembly includes a first connecting strip (8), a rotating shaft (9), and a second connecting strip (10). One end of the first connecting strip (8) is fixedly connected to one end of a first fixing ring (7). The outer wall of the rotating shaft (9) is rotatably connected to one end of the first connecting strip (8). One end of the second connecting strip (10) is rotatably connected to the outer wall of the rotating shaft (9). One end of the second connecting strip (10) is fixedly connected to one end of a second fixing ring (11).

3. The granulation apparatus for pharmaceutical production according to claim 1, characterized in that: The pelletizing assembly includes an extrusion blade (18), a drive column (19), and a stirring blade (20). One side of the extrusion blade (18) is rotatably connected to the top of the fixed disk (17). The outer wall of the drive column (19) is rotatably connected to the inside of the fixed disk (17). The inner wall of the stirring blade (20) is fixedly connected to one end of the drive column (19). The output end of the motor (21) is connected to one end of the drive column (19).

4. A granulation apparatus for pharmaceutical production according to claim 1, characterized in that: The drive assembly includes a drive gear (22), a drive gear (23), and a second motor (24). One side of the drive gear (22) is fixedly connected to one side of the extrusion blade (18), and one end of the drive gear (23) is fixedly connected to the output end of the second motor (24). The outer wall of the second motor (24) is fixedly connected to the inside of the base (1).

5. A granulation apparatus for pharmaceutical production according to claim 1, characterized in that: The extension tube (15) has multiple fixing pins (25) slidably connected inside, and each fixing pin (25) has a limit plate (26) fixedly connected to its outer wall.

6. A granulation apparatus for pharmaceutical production according to claim 1, characterized in that: The extension tube (15) is provided with a plurality of springs (27), one end of each spring (27) is fixedly connected to the inside of the extension tube (15), and the other end of each spring (27) is fixedly connected to one end of the fixing pin (25).

7. A granulation apparatus for pharmaceutical production according to claim 1, characterized in that: The top of the extension tube (15) is slidably connected to a sealing cap (28), and the top of the sealing cap (28) is fixedly connected to multiple handles (29).

8. A granulation apparatus for pharmaceutical production according to claim 7, characterized in that: The top of the sealing cap (28) is fixedly connected to the feed pipe (30), and the handles (29) are arranged in a symmetrical array and fixedly connected to the top of the sealing cap (28).

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