Reagent bottle and sample analysis equipment

Abstract

The utility model discloses a reagent bottle and sample analysis equipment, the reagent bottle comprises a bottle body and a bottle cap, the bottle body is a blow molding part, and the bottle body is provided with a bottle opening; the bottle cap is an injection molding part and comprises a cap body and a shielding part, the cap body is detachably connected with the bottle body so as to cover the bottle opening, the cap body is provided with a liquid suction hole, the liquid suction hole is communicated with the bottle opening, the shielding part is hinged to the cap body, the shielding part can rotate to shield the liquid suction hole so that the bottle opening can be sealed by the bottle cap, and the shielding part can rotate to expose the liquid suction hole. And external equipment can suck liquid in the bottle body through the liquid suction hole. According to the reagent bottle, the bottle body is manufactured in a blow molding mode, the bottle cap is manufactured in an injection molding mode, and therefore the reagent bottle has the advantage of being low in manufacturing cost.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical apparatuses, and particularly relates to a reagent bottle and a sample analysis device. BACKGROUND

[0002] The sample analysis device is used in the medical diagnosis field to perform method steps such as pipetting, sample adding, mixing, and measuring. Through such an analysis device, at least one detection reagent can be manually or automatically added to human or animal body fluid or other fluid containing analytes, and finally the amount of certain substances or certain functions in the body is detected by using biological, chemical, physical, or other principles.

[0003] In the related art, the sample analysis device is provided with a reagent bottle to carry detection reagents. However, the reagent bottle usually includes many parts, resulting in a high manufacturing cost of the reagent bottle. CONTENT OF THE UTILITY MODEL

[0004] The embodiments of the present application provide a reagent bottle and a sample analysis device, which can reduce the manufacturing cost of the reagent bottle.

[0005] In a first aspect, the embodiments of the present application provide a reagent bottle, comprising:

[0006] a bottle body, the bottle body being a blow-molded part, the bottle body being provided with a bottle opening; and

[0007] a bottle cap, the bottle cap being an injection-molded part, the bottle cap comprising a cap body and a shielding piece, the cap body being detachably connected with the bottle body to be arranged on the bottle opening, the cap body being provided with a liquid suction hole, the liquid suction hole being in communication with the bottle opening, the shielding piece being hingedly connected with the cap body, the shielding piece being capable of being rotated to shield the liquid suction hole, so that the bottle cap seals the bottle opening, and the shielding piece being capable of being rotated to expose the liquid suction hole, so that an external device performs liquid suction in the bottle body through the liquid suction hole.

[0008] In a second aspect, the embodiments of the present application provide a reagent bottle, comprising:

[0009] a bottle body, the bottle body being provided with a bottle opening; and

[0010] The bottle cap is an integrally formed plastic part, comprising a cap body, a shielding piece and a first elastic piece, the cap body is detachably connected with the bottle body to cover the bottle mouth, the cap body is provided with a liquid suction hole, the liquid suction hole is in communication with the bottle mouth, the shielding piece is movably connected with the cap body, the shielding piece can be moved to shield the liquid suction hole so that the bottle cap seals the bottle mouth, and the shielding piece can be moved to expose the liquid suction hole to allow external equipment to perform liquid suction in the bottle body through the liquid suction hole; wherein when the opening angle of the shielding piece is less than a first preset value, the first elastic piece can drive the shielding piece to shield the liquid suction hole, the opening angle of the shielding piece is the included angle between the shielding piece and the plane of the hole of the liquid suction hole; when the opening angle of the shielding piece is greater than the first preset value, the first elastic piece can drive the shielding piece to expose the liquid suction hole.

[0011] In a third aspect, the embodiments of the present application provide a sample analysis device, comprising:

[0012] A reagent containing mechanism is configured to contain the reagent bottle as described above; and

[0013] A reagent dispensing mechanism is configured to move the reagent carried by the reagent bottle in the reagent containing mechanism to a reaction container.

[0014] The technical effects of the embodiments of the present application are:

[0015] When the cap body covers the bottle body, the liquid suction hole of the cap body can be shielded or exposed by rotating the shielding piece, so that the protection of the reagent in the bottle body can be realized by shielding the liquid suction hole, and the liquid suction operation of the external equipment can be allowed by exposing the liquid suction hole. On this basis, by adopting the blow molding method to prepare the bottle body and the injection molding method to prepare the bottle cap, the overall parts of the reagent bottle can be less, and the manufacturing process can be simpler, so that the manufacturing cost of the reagent bottle can be reduced. BRIEF DESCRIPTION OF DRAWINGS

[0016] The technical solutions of the present application and their beneficial effects will become apparent through the following detailed description of the specific embodiments of the present application in conjunction with the accompanying drawings.

[0017] Figure 1 The structure schematic diagram of the reagent bottle provided by the embodiments of the present application is shown.

[0018] Figure 2 The first structure schematic diagram of the bottle cap is shown. Figure 1 The partial cross-sectional view of the bottle cap and the bottle body is shown.

[0019] Figure 3 The first structure schematic diagram of the bottle cap is shown. Figure 1 The first structure schematic diagram of the bottle cap is shown.

[0020] Figure 4 4a, 4b, and 4c are respectively Figure 1 The diagram shows the reagent bottle in a sealed state, a slightly closed state, and an open state.

[0021] Figure 5 for Figure 1 The diagram shows a structural schematic of the bottle.

[0022] Figure 6 for Figure 1 The diagram shows the second structural design of the bottle cap.

[0023] Figure 7 for Figure 6 The image shows a cross-sectional view of the bottle cap.

[0024] Figure 8 This is a schematic diagram of the structure of a sample analysis device according to an embodiment of this application.

[0025] Figure 9 for Figure 8 The schematic diagram of the first opening device shown is as follows. Figure 1 .

[0026] Figure 10 for Figure 8 The schematic diagram of the first opening device shown is as follows. Figure 2 .

[0027] Figure 11 for Figure 8 The schematic diagram of the first opening device shown is as follows. Figure 3 .

[0028] Figure 12 In the diagrams 12a, 12b, 12c, 12d, 12e, 12f, 12g, and 12h, respectively, it is a schematic diagram of the state from the first step to the eighth step in the opening process of the first opening device of this application embodiment.

[0029] Figure 13 In the middle, 13a, 13b, 13c, 13d, 13e, 13f, 13g, and 13h are respectively Figure 12 Partial schematic diagrams of the pushers corresponding to 12a, 12b, 12c, 12d, 12e, 12f, 12g and 12h.

[0030] Figure 14 Figures 14a, 14b, 14c, and 14d are schematic diagrams of the first to fourth steps in the process of sealing the bottle opening with the driving shield of the first cap opening device according to an embodiment of this application.

[0031] Figure 15 for Figure 8 The schematic diagram of the second cover opening device shown is as follows.Figure 1 .

[0032] Figure 16 For Figure 8 Structure diagram of the second uncapping device Figure 2 .

[0033] Figure 17 17a, 17b, 17c, 17d in the figure are respectively state diagrams of the first to fourth steps in a working process of the second uncapping device of the embodiment of the application.

[0034] The various reference numerals in the figure are respectively:

[0035] 100, bottle body;

[0036] 11, main body part; 12, bottle mouth part; 121, bottle mouth; 13, first limiting member;

[0037] 200, bottle cap;

[0038] 21, cap body; 211, liquid suction hole; 212, first side wall; 213, first top wall; 214, first sealing part; 215, third sealing part; 216, second connecting part; 22, shielding member; 221, second sealing part; 222, second operation part; 223, first operation part; 23, first elastic member; 24, hinged member; 241, first part; 242, second part; 25, second limiting member; 26, third limiting member; 261, abutting surface; 262, guide inclined surface; 263, easily deformable inclined surface;

[0039] 300, reagent accommodating mechanism;

[0040] 400, reagent dispensing mechanism;

[0041] 41, first uncapping device; 411, first mounting rack; 412, first driving unit; 413, pushing member; 414, buffer assembly; 4141, first rotating member; 4142, second rotating member; 415, first mounting seat; 416, second driving unit; 417, pressing assembly; 4171, second mounting rack; 4172, pressing member; 4172a, mounting part; 4172b, pressing part; 4173, second elastic member; 4174, third elastic member; 4175, first reset member; 4176, fourth elastic member; 42, second uncapping device; 421, third mounting rack; 422, third driving unit; 423, pressing-down assembly; 4231, pressing-down member; 424, second mounting seat; 425, fourth driving unit; 43, pipetting device;

[0042] 500, rack;

[0043] 51, pre-uncapping position;

[0044] 600、Scheduling mechanism. DETAILED DESCRIPTION

[0045] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by a person skilled in the art without creative work fall within the scope of protection of the present application.

[0046] Please refer to Figure 1 and Figure 2 The reagent bottle provided in the embodiments of the present application comprises a bottle body 100 and a bottle cap 200. The bottle body 100 is provided with a bottle opening 121. The bottle cap 200 is installed on the bottle body 100 to seal the bottle opening 121.

[0047] In some embodiments, the bottle body 100 is an integrally formed plastic piece. For example, the bottle body 100 is a blow-molded piece, so that the bottle body 100 has the advantages of easy molding and low manufacturing cost.

[0048] In some embodiments, the bottle body 100 is a polyethylene piece, so that the bottle body 100 is suitable for the blow molding process and can avoid the reaction between the bottle body 100 and the reagent, which may cause the denaturation of the reagent and the corrosion of the bottle body 100.

[0049] Of course, in some other embodiments, the bottle body 100 can also be made of glass, metal or alloy, which is not limited in the embodiments of the present application.

[0050] The bottle cap 200 comprises a cap body 21 and a shielding piece 22. The cap body 21 is connected with the bottle body 100 to cover the bottle opening 121. The cap body 21 is provided with a liquid suction hole 211, which is in communication with the bottle opening 121. The shielding piece 22 is hingedly connected with the cap body 21, and can be rotated to shield the liquid suction hole 211 to seal the bottle opening 121, and can be rotated to expose the liquid suction hole 211 to allow an external device (such as a liquid suction needle) to suck the reagent carried in the reagent bottle through the liquid suction hole 211. Therefore, the opening and closing of the bottle opening 121 can be realized by simply rotating the shielding piece 22 to shield or expose the liquid suction hole 211, so that the reagent bottle has the advantage of convenient use.

[0051] In some embodiments, the bottle cap 200 can be an integrally formed plastic piece, so that the bottle cap 200 has the advantages of easy molding and low cost.

[0052] For example, the bottle cap 200 can be an injection-molded piece, so that the cap body 21 and the shielding piece 22 are integrally injection molded, and the bottle cap 200 has the advantages of easy molding and low manufacturing cost.

[0053] In some embodiments, the bottle cap 200 is made of polypropylene, so that the bottle cap 200 is suitable for injection molding process and can avoid the situation that the reagent is denatured and the bottle body 100 is corroded by the reagent.

[0054] Of course, in some other embodiments, the bottle cap 200 can also be made of glass, metal or alloy, which is not limited in the embodiments of the application.

[0055] It can also be understood that when the bottle body 100 is a blow molding piece and the bottle cap 200 is an injection molding piece, the overall manufacturing cost of the reagent bottle can be lower.

[0056] In some embodiments, the bottle body 100 and the cap 21 are detachably connected to facilitate disassembly of the bottle cap 200.

[0057] For example, the bottle body 100 and the cap 21 can be threadedly connected. Further, the threads on the bottle body 100 can be manufactured by a blow molding process, and the threads on the cap 21 can be manufactured by an injection molding process, so as to realize detachable connection of the bottle body 100 and the cap 21 at low cost.

[0058] Please continue to refer to Figure 3 In some embodiments, the bottle cap 200 further comprises a hinge 24 connected with the cap 21 and the shielding piece 22 respectively, so that the cap 21 and the shielding piece 22 are hinged. For example, the hinge 24 can be connected to the first side of the cap 21 in the circumferential direction.

[0059] For example, the hinge 24 can include a first part 241 and a second part 242, the first part 241 is connected with the shielding piece 22, the second part 242 is connected with the cap 21, the first part 241 and the second part 242 are connected, and the first part 241 can rotate around the connection between the first part 241 and the second part 242, so as to drive the shielding piece 22 to rotate around the cap 21.

[0060] Then, when the bottle cap 200 is an integral injection molding piece, compared with the situation that the hinge 24, the cap 21 and the shielding piece 22 are all independent parts, the embodiments of the application can reduce the number of parts and the assembly steps of the bottle cap 200, so as to reduce the manufacturing cost and difficulty of the bottle cap 200.

[0061] As shown in Figure 2 In some embodiments, the shielding piece 22 protrudes a second sealing part 221, and the second sealing part 221 is in interference fit with the inner circumferential surface of the liquid suction hole 211, so as to seal the bottle mouth 121 of the bottle cap 200.

[0062] Correspondingly, please continue to referFigure 4 During the rotation of the blocking member 22, it can have at least the following states:

[0063] The shielding member 22 can be in a sealed state. In the sealed state, the second sealing part 221 is inserted into the liquid suction hole 211 to seal the liquid suction hole 211, thereby sealing the bottle mouth 121.

[0064] The shielding member 22 can be in a slightly closed state, and can rotate from a sealed state to a slightly closed state towards exposing the suction hole 211. In the slightly closed state, the second sealing part 221 shields the suction hole 211. Furthermore, the contact area between the second sealing part 221 and the inner circumferential surface of the suction hole 211 in the slightly closed state is smaller than the contact area in the sealed state. At this time, there may or may not be a venting gap between the inner circumferential surface of the suction hole 211 and the second sealing part 221 that connects to the outside of the reagent bottle. This embodiment of the application does not limit this.

[0065] The shield 22 can also be in an open state, in which the shield 22 fully exposes the suction hole 211, so that external devices (such as suction needles) can draw the reagent carried in the reagent bottle through the suction hole 211.

[0066] like Figure 3 As shown, in some embodiments, at least one of the bottle body 100 and the bottle cap 200 is provided with a first elastic member 23. When the opening angle of the blocking member 22 is less than a first preset value, the first elastic member 23 can drive the blocking member 22 to block the liquid absorption hole 211. The opening angle of the blocking member 22 is the angle between the blocking member 22 and the plane where the opening of the liquid absorption hole 211 is located.

[0067] Therefore, during the use of the reagent bottle, the blocking member 22 can be driven by an external device to rotate to an opening angle less than a first preset value, thereby unsealing the bottle opening 121 (or the suction hole 211). After the force of the external device is removed, the first elastic member 23 drives the blocking member 22 to rotate in the opposite direction to a slightly closed state. This eliminates the need for the external device to precisely rotate the blocking member 22 to the slightly closed state, reducing the difficulty of opening the bottle. In addition, when the external device does not need to suction liquid, the first elastic member 23 can drive the blocking member 22 to block the suction hole 211 to protect the reagent inside the bottle 100.

[0068] In some embodiments, when the opening angle of the shield 22 is greater than a first preset value, the first elastic member 23 can drive the shield 22 to expose the suction hole 211. Thus, when suction is required, the external device rotates the shield 22 to a position greater than the first preset value, facilitating the rotation of the shield 22 by the first elastic member 23 and maintaining it in the open state, so that the external device can draw the reagent contained in the reagent bottle through the suction hole 211.

[0069] It can also be understood that the first elastic member 23 can not only realize the selective rotation of the shielding member 22 to the micro-closed state or the cover-opened state, but also make the bottle cap 200 have the advantages of simple structure and low manufacturing cost.

[0070] In some embodiments, the first preset value can be 40° to 60°.

[0071] It can be understood that, on the one hand, if the first preset value is too small, the shielding member 22 needs to be driven with precise force in the process of rotating to unseal the liquid suction hole 211, so as to avoid the opening angle of the shielding member 22 being greater than the first preset value, and then the first elastic member 23 can drive the shielding member 22 to rotate to the micro-closed state, which finally leads to a greater difficulty in opening the cover by the external device. On the other hand, if the first preset value is too large, the shielding member 22 needs to be rotated to a larger opening angle, so that the first elastic member 23 can drive the shielding member 22 to rotate to expose the liquid suction hole 211, and thus the external device needs to exert a larger force and a larger driving stroke to rotate the shielding member 22, which finally leads to a greater difficulty in opening the cover by the external device. It can be seen that the embodiments of the present application can make the external device more simply and conveniently control the rotating state of the shielding member 22.

[0072] For example, the first preset value can be 40°, 43.4°, 45°, 46.7°, 48°, 50°, 52.3°, 54°, 55°, 57.8°, 59° or 60°, which is not limited in the embodiments of the present application.

[0073] In some embodiments, one end of the first elastic member 23 is connected to the outer circumferential side of the cap body 21, and the other end of the first elastic member 23 is connected to the shielding member 22. For example, the first elastic member 23 can be connected to the side surface of the shielding member 22 close to the liquid suction hole 211.

[0074] Then, when the bottle cap 200 is an integrally formed plastic member, the number of parts of the bottle cap 200 can be reduced, and the manufacturing cost can be reduced.

[0075] In some embodiments, the first elastic member 23 can be in a strip shape. When the opening angle of the shielding member 22 is equal to the first preset value, the first elastic member 23 is in a straight state; when the opening angle of the shielding member 22 is less than the first preset value, one end of the first elastic member 23 connected to the shielding member 22 is bent towards the direction close to the liquid suction hole 211, so as to drive the shielding member 22 to shield the liquid suction hole 211; and when the opening angle of the shielding member 22 is greater than the first preset value, one end of the first elastic member 23 connected to the shielding member 22 is bent away from the direction of the liquid suction hole 211, so as to drive the shielding member 22 to expose the liquid suction hole 211.

[0076] In some embodiments, a second connecting portion 216 protrudes from the outer periphery of the cap 21. Both the hinge 24 and the first elastic member 23 are connected between the second connecting portion 216 and the blocking member 22. Thus, by connecting the hinge 24 and the first elastic member 23 to the same position on the cap 21, the integral molding of the bottle cap 200 is simplified.

[0077] In some embodiments, there are two hinges 24, with the first elastic member 23 located between the two hinges 24. Therefore, when the first elastic member 23 drives the blocking member 22 to rotate, the hinges 24 located on different sides of the first elastic member 23 can be subjected to more even force, so that the blocking member 22 can rotate more accurately and stably to block or expose the suction hole 211.

[0078] like Figure 2 As shown, in some embodiments, the shield 22 further includes a second operating part 222, which protrudes from the outer periphery of the cover 21 to allow an external device to drive the shield 22 to rotate.

[0079] For example, the outer periphery of the cap 21 includes a first side and a second side facing different directions. The cap 21 is hinged to the shield 22 on the first side. The shield 22 is provided with a second sealing part 221 and a second operating part 222. The second sealing part 221 is interference-fitted with the inner peripheral surface of the liquid suction hole 211 so that the cap 200 seals the bottle mouth 121. The second operating part 222 protrudes from the second side and is used to be driven by an external force to rotate in a direction away from the cap 21, thereby driving the shield 22 to rotate in a direction that exposes the liquid suction hole 211, so as to unseal the bottle mouth 121.

[0080] Taking the first side and the second side as the right and left sides respectively, with the blocking member 22 located on the upper side of the cover 21 as an example, the second operating part 222 can be driven by an external force to rotate to the upper right, thereby driving the blocking member 22 to rotate in the direction of exposing the suction hole 211 (i.e., upper right). At this time, since the blocking member 22 is hinged to the right side of the cover 21, and the second operating part 222 is located on the left side of the cover 21, the lever arm of the external force acting on the second operating part 222 is longer, so as to drive the blocking member 22 to rotate in the direction of exposing the suction hole 211 (i.e., upper left) with less effort.

[0081] It should be noted that in actual use, the first side and the second side can be adjacent sides of the outer periphery of the cover 21, or they can be opposite sides. That is to say, the first side can be the left side of the cover 21 and the second side can be the front or rear side of the cover 21, or the first side can be the right side of the cover 21 and the second side can be the front, rear or left side of the cover 21. This application embodiment does not limit this.

[0082] It should be noted that, in the embodiments of the present application, the shielding piece 22 rotates towards the direction of exposing the liquid suction hole 211 to unseal the bottle mouth 121, and it can also be understood that the shielding piece 22 rotates towards the direction of exposing the liquid suction hole 211 to unseal the second sealing part 221 and the liquid suction hole 211, thereby achieving unsealing of the bottle mouth 121.

[0083] In some embodiments, the shielding piece 22 includes a shielding part and a first operation part 223 connected thereto, the shielding part is used to shield the liquid suction hole 211, and the first operation part 223 protrudes from the side (i.e. the first side) of the hinge 24 on the circumference of the cover body 21. The first operation part 223 can receive external force and rotate towards the bottle body 100 to drive the shielding part to rotate to expose the liquid suction hole 211.

[0084] For example, the shielding part can be the part of the shielding piece 22 which protrudes with the second sealing part 221 described above, and is connected between the first operation part 223 and the first operation part 223.

[0085] Then, continuing to take the example that the shielding piece 22 is located on the upper side of the cover body 21, in the actual opening process, the shielding piece 22 can be brought to expose the liquid suction hole 211 by only pushing the second operation part 222 upwards, or by only pressing the first operation part 223 downwards, or by simultaneously pushing the second operation part 222 upwards and pressing the first operation part 223 downwards, of course, pushing the second operation part 222 upwards and pressing the first operation part 223 downwards can also be performed step by step, and the embodiments of the present application do not limit this, so that the shielding piece 22 can meet the opening requirements of more different scenes.

[0086] Taking the example that pushing the second operation part 222 upwards and pressing the first operation part 223 downwards are performed step by step:

[0087] First, the second operation part 222 can be pushed upwards to drive the shielding piece 22 to rotate towards the direction of exposing the liquid suction hole 211. At this time, the shielding piece 22 can be directly rotated to the micro-closed state, or the shielding piece 22 can be reversely rotated a certain angle to the micro-closed state under the driving of the first elastic piece 23 after being rotated to unseal the bottle mouth 121 (or unseal the liquid suction hole 211). In the micro-closed state, the shielding piece 22 can separate the inside and outside of the reagent bottle to avoid foreign matter directly falling into the bottle body 100 from the liquid suction hole 211 to pollute the reagent, and can reduce the contact between the reagent in the reagent bottle and the flowing air outside, thereby improving the stability and reliability of the reagent in the reagent bottle.

[0088] Then, when it is needed to suck the reagent loaded in the reagent bottle through an external device (such as a liquid suction needle) from the liquid suction hole 211, the first operation part 223 can be pressed down to expose the liquid suction hole 211, so that the shielding piece 22 is in the uncapped state, thereby allowing the liquid suction needle to suck the reagent loaded in the reagent bottle.

[0089] Finally, when it is needed to seal the bottle opening 121 again, the middle part or the second operation part 222 of the shielding piece 22 can be pressed to make the shielding piece 22 rotate to the second sealing part 221 again to be in interference fit with the inner circumferential surface of the liquid suction hole 211, so as to be in the sealed state.

[0090] Therefore, in the whole process of rotating the shielding piece 22 from the sealed state to the uncapped state, a large kinetic energy is needed when the shielding piece 22 rotates from the sealed state to the micro-closed state, thereby easily causing the reagent bottle to shake, and further causing the reagent carried in the reagent bottle to splash out from the liquid suction hole 211. Therefore, in the actual working process of the reagent bottle of the present application, the shielding piece 22 can be first opened to the micro-closed state through the second operation part 222, and then each time the external device (such as the liquid suction needle) sucks the reagent loaded in the reagent bottle from the liquid suction hole 211, the shielding piece 22 can be opened from the micro-closed state to the uncapped state only through the first operation part 223, which can make the uncapping operation in the subsequent each time of liquid suction of the external device more simple and labor-saving, and can avoid the reagent bottle from shaking and causing the reagent to splash out in the process of liquid suction of the external device each time.

[0091] In some embodiments, the first operation part 223 and the second operation part 222 are located at opposite ends of the shielding piece 22.

[0092] It can be understood that the shielding piece 22 is hinged to the first side of the cover body 21, so that the rotation fulcrum (i.e. the hinge 24) of the shielding piece 22 is also located at the first side. The first operation part 223 protrudes from the first side of the cover body 21, and the first operation part 223 and the second operation part 222 are located at opposite ends of the shielding piece 22, which means that the second operation part 222 is away from the first side of the cover body 21, so that the force arm formed when the external device pushes the first operation part 223 upward is longer, so as to be more labor-saving to unseal the bottle opening 121, and also can reduce the deformation of the first operation part 223.

[0093] Please continue to refer to Figure 5 and Figure 6 In some embodiments, the bottle body 100 is provided with a first limiting piece 13, and the bottle cap 200 is provided with a second limiting piece 25, and the first limiting piece 13 is used to abut against the second limiting piece 25 to limit the stroke of the cover body 21 in the tightening direction.

[0094] It can be understood that the bottle body 100 and the cap body 21 can be screwed together as mentioned above. Therefore, the angle of the bottle cap 200 in the circumferential direction of the bottle mouth 121 after the bottle cap 200 is screwed to the bottle body 100 can be accurately controlled by the cooperation of the first limiting member 13 and the second limiting member 25, so that the first operation part 223 and the second operation part 222 are located at the preset positions in the circumferential direction of the bottle mouth 121. Then, when the bottle body 100 is fixed to the external device, the external device can more accurately drive the first operation part 223 and the second operation part 222.

[0095] In some embodiments, the bottle cap 200 further comprises a third limiting member 26, which is used to abut against the first limiting member 13 to limit the travel of the cap body 21 in the loosening direction.

[0096] Therefore, after the cap body 21 is screwed in place, the third limiting member 26 can prevent the cap body 21 from loosening to avoid the cap body 21 rotating in the loosening direction due to vibration during transportation of the reagent bottle. In this way, the reagent in the bottle body 100 can be prevented from leaking from the bottle mouth 121, and the positions of the first operation part 223 and the second operation part 222 in the circumferential direction of the bottle mouth 121 can be prevented from changing due to rotation of the cap body 21, so that the external device can accurately drive the first operation part 223 and the second operation part 222.

[0097] In some embodiments, the third limiting member 26 and the second limiting member 25 are arranged at intervals in the circumferential direction of the cap body 21 to form a space for clamping the first limiting member 13. In this way, after the cap body 21 is screwed in place, the first limiting member 13 and the second limiting member 25 can provide a better positioning effect to ensure the accuracy of the positions of the first operation part 223 and the second operation part 222 in the circumferential direction of the bottle mouth 121.

[0098] In some embodiments, the third limiting member 26 comprises an abutting surface 261 and a guide inclined surface 262. The abutting surface 261 is used to abut against the first limiting member 13 to limit the rotation of the cap body 21 in the loosening direction. The guide inclined surface 262 is connected to the abutting surface 261 and is located on one side of the abutting surface 261 in the loosening direction. The guide inclined surface 262 is used to guide the first limiting member 13 to move to the side of the abutting surface 261 of the third limiting member 26 during screwing of the cap body 21. In this way, during screwing of the cap body 21, the guide inclined surface 262 and the first limiting member 13 can provide a better guiding effect to make the first limiting member 13 more conveniently clamped between the third limiting member 26 and the second limiting member 25.

[0099] In some embodiments, the guide slope 262 comprises a first guide slope, which is increasing in distance from the peripheral surface of the cover 21 in the tightening direction. Thus, the first limiting member 13 can slide along the first guide slope relative to the second limiting member 25 during the tightening of the cover 21.

[0100] In some embodiments, the guide slope 262 comprises a second guide slope, which is increasing in distance from the orifice of the liquid suction hole 211 in the tightening direction. Alternatively, it can also be understood that the second guide slope is increasing in distance from the shielding member 22. Thus, the first limiting member 13 can slide along the second guide slope relative to the second limiting member 25 during the tightening of the cover 21.

[0101] In some embodiments, the third limiting member 26 further comprises a deformable slope 263. In the case that the shielding member 22 seals the bottle mouth 121, the deformable slope 263 is located on the side of the third limiting member 26 away from the shielding member 22, which is increasing in distance from the orifice of the liquid suction hole 211 in the tightening direction, so as to thin the end of the third limiting member 26 close to the second limiting member 25. Then, during the tightening of the cover 21, the end of the third limiting member 26 close to the second limiting member 25 can be more easily deformed, so that the first limiting member 13 can be more conveniently clamped between the third limiting member 26 and the second limiting member 25.

[0102] In some embodiments, the bottle body 100 comprises a main body part 11 and a bottle mouth part 12. The bottle mouth part 12 is protruded on one side of the main body part 11, and the end of the bottle mouth part 12 away from the main body part 11 forms the bottle mouth 121.

[0103] Then, the main body part 11 can be used to fix the bottle body 100 by external equipment. Thus, the external equipment can fix the bottle body 100 through the main body part 11 when driving the shielding member 22, so as to reduce or even avoid the shaking of the bottle body 100, and further avoid the splashing of the reagent carried in the reagent bottle from the liquid suction hole 211.

[0104] In some embodiments, the bottle mouth part 12 and the first limiting member 13 are protruded on the same side of the main body part 11, so as to facilitate the cooperation with the second limiting member 25 and the third limiting member 26 on the cover 21.

[0105] Correspondingly, the second limiting member 25 and the third limiting member 26 can be arranged on the outer periphery of the cover 21, which is not limited in the embodiments of the present application.

[0106] Of course, in some other embodiments, the second limiting member 25 and the third limiting member 26 can also be arranged on the inner periphery of the cover 21, which is not limited in the embodiments of the present application.

[0107] In some embodiments, the bottle mouth portion 12 is provided with an external thread on the outer periphery thereof to be screwed with the cap 21.

[0108] Please continue to refer to Figure 7 In some embodiments, the cap 21 comprises a first top wall 213 and a first side wall 212, the first side wall 212 being connected to the outer periphery of the first top wall 213, and the first side wall 212 being screwed with the bottle body 100 so that the first top wall 213 covers the bottle mouth 121.

[0109] For example, the bottle mouth portion 12 of the bottle body 100 can be provided with an external thread, and the first side wall 212 can be provided with an internal thread to be screwed with the bottle mouth portion 12, so that the cap 21 has the advantage of being easy to disassemble.

[0110] In some embodiments, the cap 21 further comprises a first sealing portion 214. The first sealing portion 214 is protruded from the side of the first top wall 213 away from the bottle mouth 121, and the inner periphery of the first sealing portion 214 forms the liquid suction hole 211. The inner periphery of the first sealing portion 214 is in interference fit with the shielding member 22 to seal the liquid suction hole 211.

[0111] It can be understood that, in the process of screwing the cap 21 with the bottle body 100 through the first side wall 212, when the cap 21 is tightened, the first side wall 212 is prone to large deformation, and the deformation is prone to be directly transmitted to the first top wall 213. At this time, if the first top wall 213 directly forms the liquid suction hole 211, the inner periphery of the liquid suction hole 211 is prone to large deformation, thereby affecting the sealing of the liquid suction hole 211 by the shielding member 22. In contrast, the embodiments of the present application form the liquid suction hole 211 by the first sealing portion 214 protruded from the first top wall 213, so that the liquid suction hole 211 is away from the first side wall 212, and thus the deformation of the first side wall 212 is difficult to be transmitted to the first sealing portion 214, thereby reducing or even eliminating the deformation of the liquid suction hole 211 when the cap 21 is tightened, and finally improving the sealing effect of the bottle cap 200.

[0112] The first sealing portion 214 can be an annular protrusion, so that the inner periphery of the first sealing portion 214 forms the liquid suction hole 211.

[0113] In some embodiments, the shielding member 22 is provided with a second sealing portion 221, and the outer periphery of the second sealing portion 221 is in interference fit with the inner periphery of the liquid suction hole 211 (i.e. the inner periphery of the first sealing portion 214) to seal the liquid suction hole 211.

[0114] In some embodiments, the second sealing portion 221 can be an annular protrusion, and the second sealing portion 221 can also be a solid structure, which is not limited in the embodiments of the present application.

[0115] In some embodiments, the cover 21 further comprises a third sealing portion 215. The third sealing portion 215 is protruded from one side of the first top wall 213 towards the bottle mouth 121, and the outer circumferential surface of the third sealing portion 215 is in interference fit with the inner circumferential surface of the bottle mouth 121 to seal the bottle mouth 121.

[0116] It can be understood that, as mentioned above, when the cover 21 is screwed, a certain deformation is likely to occur at the first side wall 212 and is likely to be transmitted to the first top wall 213 during the process that the cover 21 is screwed with the bottle body 100 by the first side wall 212. At this time, if the sealing is formed by the first side wall 212 and the outer circumferential surface of the bottle mouth portion 12 of the bottle body 100, or by the first top wall 213 and the opening end surface of the bottle mouth 121, the sealing failure is likely to occur due to the excessive deformation of the first side wall 212 and the first top wall 213. In contrast, the third sealing portion 215 protruded from the first top wall 213 is in interference fit with the inner circumferential surface of the bottle mouth 121 to seal the bottle mouth 121 in the embodiment of the application, so that the deformation at the first side wall 212 is difficult to be transmitted to the third sealing portion 215, thereby reducing or even eliminating the deformation at the third sealing portion 215 when the cover 21 is screwed, and improving the sealing effect at the bottle mouth 121.

[0117] It can also be understood that, the sealing between the cover 21 and the bottle mouth 121 is achieved by forming the third sealing portion 215 on the cover 21, so that the reagent bottle can not need to be sealed by the sealing ring between the first side wall 212 and the bottle mouth portion 12, and thus the manufacturing cost of the reagent bottle can be further reduced.

[0118] The embodiment of the application further provides a reagent bottle, which comprises a bottle body 100 and a bottle cap 200. The bottle body 100 is provided with a bottle mouth 121. The bottle cap 200 is an integrally formed plastic piece, and comprises a cover 21, a shielding piece 22 and a first elastic piece 23. The cover 21 is detachably connected with the bottle body 100 to cover the bottle mouth 121. The cover 21 is provided with a liquid suction hole 211, and the liquid suction hole 211 is in communication with the bottle mouth 121. The shielding piece 22 is movably connected with the cover 21, and the shielding piece 22 can be moved to shield the liquid suction hole 211 to seal the bottle mouth 121, and can be moved to expose the liquid suction hole 211 to allow an external device to suck the reagent carried in the bottle body 100 through the liquid suction hole 211. When the opening angle of the shielding piece 22 is less than a first preset value, the first elastic piece 23 can drive the shielding piece 22 to shield the liquid suction hole 211. The opening angle of the shielding piece 22 is the included angle between the shielding piece 22 and the plane in which the opening of the liquid suction hole 211 is located.

[0119] It can be understood that, in the embodiments of the present application, the bottle cap 200 can be opened and closed by rotating the shielding piece 22; and when the opening angle of the shielding piece 22 is less than the first preset value, the shielding piece 22 can be automatically driven by the first elastic piece 23 to shield the liquid suction hole 211, so as to protect the reagent carried in the bottle body 100. On this basis, the cap body 21, the shielding piece 22 and the first elastic piece 23 are integrally formed by the bottle cap 200, so that the bottle cap 200 has the advantage of low manufacturing cost, so that the reagent bottle as a whole also has the advantage of low manufacturing cost.

[0120] In some embodiments, the specific structure of the bottle body 100 and the bottle cap 200 can be referred to the specific structure of the bottle body 100 and the bottle cap 200 described above, respectively, and the embodiments of the present application will not be repeated here.

[0121] The above is some description of the reagent bottle in the embodiments of the present application.

[0122] Please continue to refer to Figure 8 The embodiments of the present application also provide a sample analysis device, which comprises a reagent containing mechanism 300 and a reagent dispensing mechanism 400. The reagent containing mechanism 300 is used to contain the reagent bottle as described above. The reagent dispensing mechanism 400 is used to transfer the reagent carried by the reagent bottle contained by the reagent containing mechanism 300 to a reaction container. Thus, the reagent dispensing function can be realized by the sample analysis device.

[0123] For example, the reagent dispensing mechanism 400 can comprise an opening and closing cover device and a pipetting device 43. The opening and closing cover device is used to drive the shielding piece 22 to move to shield or expose the liquid suction hole 211. The pipetting device 43 is used to suck the reagent carried in the bottle body 100 through the liquid suction hole 211 and transfer it to the reaction container.

[0124] Thus, when the reagent in the reagent bottle needs to be sucked, the reagent dispensing mechanism 400 can drive the reagent bottle to expose the liquid suction hole 211 by the opening and closing cover device, and the pipetting device 43 can suck the reagent carried in the bottle body 100 through the liquid suction hole 211 and transfer it to the reaction container. When the transfer of the reagent into the reaction container is completed, the reagent dispensing mechanism 400 can drive the reagent bottle to shield the liquid suction hole 211 by the opening and closing cover device, so as to protect the reagent in the reagent bottle.

[0125] The pipetting device 43 can comprise a liquid suction needle, which can be inserted into the bottle body 100 through the liquid suction hole 211 to suck the reagent carried in the reagent bottle. The pipetting device 43 can also comprise a mechanical arm, which drives the liquid suction needle to move between the reagent containing mechanism 300 and the corresponding reaction container, so that after the liquid suction needle sucks the reagent at the reagent containing mechanism 300, it can be driven to the corresponding reaction container, so that the liquid suction needle can transfer the reagent carried in the bottle body 100 to the reaction container.

[0126] In some embodiments, the opening and closing device comprises a first opening device 41 and a second opening device 42. The first opening device 41 is configured to drive the shielding member 22 to rotate to a first preset angle in a direction exposing the liquid suction hole 211, and the second opening device 42 is configured to drive the shielding member 22 to rotate to a second preset angle in a direction exposing the liquid suction hole 211, the second preset angle being greater than the first preset angle.

[0127] Thus, the first opening device 41 and the second opening device 42 can be used to control the shielding member 22 to rotate to different opening angles.

[0128] For example, the first opening device 41 is configured to drive the shielding member 22 to rotate to unseal the bottle mouth 121, and the second opening device 42 is configured to drive the shielding member 22 to rotate to selectively expose the liquid suction hole 211 for the pipette 43 to suck the reagent carried in the bottle.

[0129] Therefore, in combination with the above, the shielding member 22 can have a sealed state, a slightly closed state and an open state. The working process of the opening and closing device can be as follows:

[0130] First, the first opening device 41 pushes the second operating part 222 upwards, thereby driving the shielding member 22 to rotate in a direction exposing the liquid suction hole 211 to an opening angle of the shielding member 22 being less than a first preset value, so as to unseal the bottle mouth 121 (or unseal the liquid suction hole 211).

[0131] Then, the first opening device 41 leaves the reagent bottle, and the shielding member 22 is driven by the first elastic member 23 to rotate reversely by a certain angle to the slightly closed state. In the slightly closed state, the shielding member 22 can separate the inside and outside of the reagent bottle to avoid foreign matter directly falling into the bottle 100 from the liquid suction hole 211 to pollute the reagent, and can reduce the contact between the reagent in the reagent bottle and the flowing air outside, thereby improving the stability and reliability of the reagent in the reagent bottle.

[0132] Next, when it is needed to suck the reagent carried in the reagent bottle from the liquid suction hole 211 by the pipette 43, the first operating part 223 can be pressed by the second opening device 42 to expose the liquid suction hole 211, so that the shielding member 22 is in the open state, thereby allowing the pipette to suck the reagent carried in the reagent bottle.

[0133] Finally, when the bottle opening 121 needs to be sealed again, the shielding piece 22 can be pushed to an opening angle less than the first preset value by the second uncapping device 42, and then the shielding piece 22 is driven to rotate to a micro-closed state by the first elastic piece 23, and the shielding piece is pressed from the micro-closed state to the sealed state by the first uncapping device 41, that is, the middle part or the second operation part 222 of the shielding piece 22 is pressed by the first uncapping device 41, so that the shielding piece 22 rotates to the second sealing part 221 again and is in interference fit with the inner circumferential surface of the liquid suction hole 211, so as to be in the sealed state.

[0134] It can be understood that during the entire process of rotating the shielding piece 22 from the sealed state to the uncapped state, especially when the shielding piece 22 rotates from the sealed state to the micro-closed state, a large kinetic energy is required, which is easy to cause the reagent bottle to shake, and then the reagent carried in the reagent bottle is splashed out of the liquid suction hole 211. Therefore, in the actual working process of the reagent bottle of the present application, the first uncapping device 41 can first open the shielding piece 22 to the micro-closed state through the second operation part 222, and then every time the pipetting device 43 needs to suck the reagent loaded in the reagent bottle from the liquid suction hole 211, the second uncapping device 42 can only open the shielding piece 22 from the micro-closed state to the uncapped state through the first operation part 223. Therefore, it can make the subsequent each time the pipetting device 43 needs to suck the liquid more simple and labor-saving, and can avoid the reagent bottle shaking during the subsequent each time the pipetting device 43 sucks the liquid, which causes the reagent to splash out.

[0135] For example, in the case that the first uncapping device 41 is used to drive the shielding piece 22 to rotate to the first preset angle in the direction of exposing the liquid suction hole 211, the opening angle of the shielding piece 22 is less than the first preset value. Therefore, the shielding piece 22 can be first driven to rotate by the first uncapping device 41, and then driven to rotate to the micro-closed state by the first elastic piece 23 in the direction of shielding the liquid suction hole 211 after the first uncapping device 41 is separated from the shielding piece 22. Then, when the pipetting device 43 needs to suck the reagent carried in the reagent bottle, the shielding piece 22 can be driven to rotate from the micro-closed state to completely expose the liquid suction hole 211 by the second uncapping device 42.

[0136] In some embodiments, in the case that the second uncapping device 42 drives the shielding piece 22 to rotate to the second preset angle in the direction of exposing the liquid suction hole 211, the opening angle of the shielding piece 22 is greater than the second preset value. Therefore, after the second uncapping device 42 drives the shielding piece 22 to rotate to the second preset angle, the second uncapping device 42 can be away from the reagent bottle to avoid position, so that the first elastic piece 23 drives the shielding piece 22 to expose the liquid suction hole 211, and then the pipetting device 43 is moved to the second uncapping device 42 to suck the liquid, so as to avoid the interference between the second uncapping device 42 and the pipetting device 43.

[0137] In some embodiments, the sample analysis device further comprises a rack 500, and the rack 500 is installed with the reagent accommodating mechanism 300. The rack 500 is provided with a pre-opening cover position 51, and the pre-opening cover position 51 is arranged outside the reagent accommodating mechanism 300 and is used to carry the reagent bottle.

[0138] The first cover opening device 41 is used to drive the shielding piece 22 of the reagent bottle at the pre-opening cover position 51 to rotate. The second cover opening device 42 is used to drive the shielding piece 22 of the reagent bottle in the reagent accommodating mechanism 300 to rotate, and the pipetting device 43 is used to carry and transfer the reagent carried by the reagent bottle in the reagent accommodating mechanism 300 to the reaction container.

[0139] Further, on the one hand, the first cover opening device 41 can avoid occupying too much space in the reagent accommodating mechanism 300; on the other hand, the sample analysis instrument can also be used to rotate the shielding piece 22 to the pre-opening cover position 51 outside the reagent accommodating mechanism 300, and then the second cover opening device 42 can simply and stably drive the shielding piece 22 to expose the liquid suction hole 211 in the reagent accommodating mechanism 300 to perform liquid suction, so as to avoid the influence of the large kinetic energy generated in the process of the shielding piece 22 from the sealed state to the unsealed state on the stability and normal operation of the reagent accommodating mechanism 300.

[0140] Correspondingly, the sample analysis instrument can also comprise a scheduling mechanism 600, and the scheduling mechanism 600 is used to schedule the reagent bottle. For example, the scheduling mechanism 600 can be used to schedule the reagent bottle to move between the pre-opening cover position 51 and the reagent accommodating mechanism 300.

[0141] Of course, in the actual use process, the first cover opening device 41 and the second cover opening device 42 can also be used to realize the liquid suction operation of the shielding piece 22 at the first preset angle and the second preset angle, so as to meet the diversified liquid suction demand of the sample analysis instrument, and the embodiments of the present application do not limit this.

[0142] The technical solutions of the embodiments of the present application will be described below in combination with the specific structure of the first cover opening device 41.

[0143] Please continue to refer to Figure 9 The first cover opening device 41 can comprise a first mounting frame 411, a first driving unit 412 and a pushing piece 413. The first driving unit 412 is mounted on the first mounting frame 411. The pushing piece 413 is in transmission connection with the first driving unit 412, and the first driving unit 412 can drive the second operation part 222 to rotate away from the cover body 21, so that the shielding piece 22 rotates away from the liquid suction hole 211. Therefore, the unsealing of the liquid suction hole 211 can be realized.

[0144] In some embodiments, the first driving unit 412 is also capable of driving the second operation part 222 to rotate towards the direction of approaching the cover 21, so as to enable the second sealing part 221 of the shielding part 22 to seal the liquid suction hole 211, thereby realizing the sealing at the liquid suction hole 211.

[0145] For example, when the second sealing part 221 seals the liquid suction hole 211 so that the bottle mouth 121 is in a sealed state, the pushing member 413 can push the second operation part 222 from bottom to top to unseal the bottle mouth 121 (or the liquid suction hole 211). When the shielding part 22 is in a micro-closed state, the pushing member 413 can push the second operation part 222 from top to bottom so that the second sealing part 221 unseals the liquid suction hole 211, and the bottle mouth 121 is in a sealed state.

[0146] The first driving unit 412 can be an electric motor, a motor, a pneumatic cylinder, etc., and the embodiments of the present application do not limit the same.

[0147] In some embodiments, the first cover opening device 41 further comprises a buffering assembly 414. The buffering assembly 414 is installed on the first mounting frame 411, and the buffering assembly 414 is located on the path of the shielding part 22 rotating under the driving of the pushing member 413, so as to provide buffering when the shielding part 22 moves towards the direction of exposing the liquid suction hole 211.

[0148] It can be understood that, as mentioned above, a large kinetic energy can be generated in the process of the shielding part 22 rotating from a sealed state to unseal the bottle mouth 121. Therefore, by buffering the shielding part 22 when unsealing the bottle mouth 121 (or the liquid suction hole 211) through the buffering assembly 414, the large kinetic energy generated by the shielding part 22 can be effectively absorbed, so that the unsealing of the liquid suction hole 211 is more stable, and the reagent in the bottle body 100 can be prevented from splashing out.

[0149] For example, the buffering assembly 414 comprises a first rotating member 4141 and a fifth elastic member (not shown in the figure). The first rotating member 4141 is rotatably installed on the first mounting frame 411. The fifth elastic member is installed on the first mounting frame 411, and the fifth elastic member is used to drive the first rotating member 4141 to rotate towards the direction of approaching the pushing member 413, so as to abut against the shielding part 22 of the reagent bottle to provide buffering.

[0150] The fifth elastic member can be a torsion spring, a compression spring, a disc spring, etc., and the embodiments of the present application do not limit the same.

[0151] In some embodiments, the buffering assembly 414 further comprises a second rotating member 4142 rotatably mounted on the first mounting frame 411, and the second rotating member 4142 is located on the opposite side of the first rotating member 4141 from the pushing member 413. When the first rotating member 4141 drives the shielding member 22 to move to the first preset angle in the direction of exposing the liquid suction hole 211, the second rotating member 4142 contacts the first rotating member 4141 and drives the first rotating member 4141 to move in the direction away from the pushing member 413.

[0152] For example, the second rotating member 4142 can be a bearing, and the first rotating member 4141 is provided with a curved surface matched with the second rotating member 4142. When the shielding member 22 of the pre-opening cover position 51 moves to the first preset angle in the direction of exposing the liquid suction hole 211, the torque applied by the second rotating member 4142 to the first rotating member 4141 drives the first rotating member 4141 to rotate in the direction away from the pushing member 413. At this time, the pushing member 413 stops pushing the shielding member 22 to rotate, so that the pushing member 413 and the first rotating member 4141 can release the shielding member 22, so as to take away the reagent bottle or drive the pushing member 413 and the first rotating member 4141 away from the reagent bottle.

[0153] In some embodiments, the pushing member 413 is provided with a first reset portion (not shown in the figure), and the first rotating member 4141 is provided with a second reset portion (not shown in the figure) located on the rotating path of the first reset portion. When the pushing member 413 drives the shielding member 22 to move in the direction of shielding the liquid suction hole 211, the first reset portion can push the second reset portion, so that the first rotating member 4141 rotates in the direction close to the pushing member 413 to reset.

[0154] For example, the second reset portion can be arranged in a reset slot of the first rotating member 4141, and the first reset portion can be a push rod movably arranged in the reset slot. When the pushing member 413 pushes the shielding member 22 to rotate to the first preset angle in the direction of exposing the liquid suction hole 211, the push rod moves in the reset slot; when the pushing member 413 resets, the push rod first moves to abut against the slot wall of the reset slot, and then drives the second rotating member 4142 to reset by pushing the slot wall of the reset slot.

[0155] In some embodiments, the sample analysis device is provided with a pre-opening cover position 51 for carrying a reagent bottle. The first cover opening device 41 is configured to drive the cover 22 of the reagent bottle at the pre-opening cover position 51 to rotate. Correspondingly, the first cover opening device 41 can further include a first mounting seat 415 and a second driving unit 416. The first mounting seat 415 is in sliding connection with the first mounting frame 411, so that the first mounting frame 411 can move towards or away from the pre-opening cover position 51. The second driving unit 416 is mounted on the first mounting seat 415, and the second driving unit 416 is in transmission connection with the first mounting frame 411, so as to drive the first mounting frame 411 to slide.

[0156] Therefore, when the bottle opening 121 of the reagent bottle at the pre-opening cover position 51 needs to be unsealed or resealed, the first mounting frame 411 can be driven by the second driving unit 416 to slide, so that the pushing piece 413 and the buffer assembly 414 on the first mounting frame 411 move towards the pre-opening cover position 51 to unseal or reseal the bottle opening 121 of the reagent bottle; after the bottle opening 121 of the reagent bottle is unsealed or resealed, the first mounting frame 411 can be driven by the second driving unit 416 to move away from the pre-opening cover position 51 to achieve avoidance.

[0157] In some embodiments, the corresponding carrying seat of the rack 500 can be provided with the pre-opening cover position 51.

[0158] In some embodiments, the second driving unit 416 can be an electric motor, a motor, a pneumatic cylinder, etc., and the present application does not limit the same.

[0159] In some embodiments, the first cover opening device 41 further includes a pressing assembly 417. The pressing assembly 417 is configured to press or release the bottle body 100 of the reagent bottle. It can be understood that, as mentioned above, a large amount of kinetic energy can be generated during the movement of the cover 22 from the sealing state to the state of unsealing the bottle opening 121. Therefore, by means of the pressing assembly 417, the bottle body 100 can be effectively prevented from shaking to avoid spilling of the reagent in the bottle body 100.

[0160] For reference Figure 9 and Figure 10 , for example, the pressing assembly 417 can include a second mounting frame 4171 and a pressing piece 4172. The second mounting frame 4171 is mounted on the first mounting seat 415. The pressing piece 4172 includes a mounting portion 4172a and a pressing portion 4172b. The mounting portion 4172a is rotatably mounted on the second mounting frame 4171, and the pressing portion 4172b is located on the side of the mounting portion 4172a close to the pre-opening cover position 51. Thus, the pressing piece 4172 can use the mounting portion 4172a as a rotation fulcrum to rotate to press or release the bottle body 100 of the reagent bottle.

[0161] In some embodiments, the pressing part 4172b can be used to press or release the main body 11 of the bottle 100.

[0162] In some embodiments, the pressing part 4172 abuts against the first mounting frame 411, and when the first mounting frame 411 moves towards the pre-opening cover position 51, the pressing part 4172b is allowed to rotate towards the pre-opening cover position 51, so as to press the bottle 100 of the reagent bottle. When the first mounting frame 411 moves away from the pre-opening cover position 51, the pressing part 4172b is pushed to rotate away from the pre-opening cover position 51, so as to release the bottle 100 of the reagent bottle.

[0163] For example, the part of the pressing part 4172 between the mounting part 4172a and the pressing part 4172b can abut against the first mounting frame 411.

[0164] Further, the movement of the first mounting frame 411 can be driven by the second driving unit 416, so as to control the pressing part 4172 to press or release the bottle 100 of the reagent bottle, so that the overall structure of the first cover opening device 41 is simpler.

[0165] It can be understood that, in the case that the first mounting frame 411 moves towards the pre-opening cover position 51 and allows the pressing part 4172b to rotate towards the pre-opening cover position 51, the pressing part 4172b can be driven to rotate downwards to press the bottle 100 of the reagent bottle by its own gravity, or can be driven to rotate by other forces, and the embodiments of the present application do not limit this.

[0166] For example, the pressing assembly 417 further comprises a second elastic member 4173, which is mounted on the second mounting frame 4171 or the first mounting seat 415, and is used to drive the pressing part 4172b to rotate towards the pre-opening cover position 51.

[0167] It can be understood that, by driving the pressing part 4172b to rotate towards the pre-opening cover position 51 by the second elastic member 4173, the pressing part 4172b can not only press the bottle 100 of the reagent bottle, but also avoid that the pressing part 4172b rotates too much towards the pre-opening cover position 51 and damages the bottle 100 of the reagent bottle. Of course, the pressing part 4172b can also be suitable for pressing reagent bottles of different heights, thereby improving the versatility of the pressing assembly 417.

[0168] In addition, the second elastic member 4173 can reduce the driving unit required by the first cover opening device 41, so as to reduce the cost of the first cover opening device 41 and the entire sample analyzer.

[0169] The second elastic member 4173 can be a torsion spring, a compression spring, a disc spring, or the like, and the embodiments of the present application do not limit the second elastic member 4173.

[0170] In some embodiments, the second mounting bracket 4171 is slidingly mounted on the first mounting seat 415, so that the second mounting bracket 4171 can move towards or away from the pre-opening cover position 51.

[0171] Therefore, when the bottle opening 121 of the reagent bottle at the pre-opening cover position 51 needs to be unsealed or resealed, the second mounting bracket 4171 slides to the pre-opening cover position 51, so that the pressing member 4172 on the second mounting bracket 4171 can rotate to press the bottle body 100 of the reagent bottle at the pre-opening cover position 51; after the bottle opening 121 of the reagent bottle is unsealed or resealed, the second mounting bracket 4171 slides away from the pre-opening cover position 51 to achieve the avoidance position.

[0172] Please continue to refer to Figure 11 In some embodiments, the pressing assembly 417 further includes a third elastic member 4174 mounted on the first mounting seat 415, and the third elastic member 4174 is used to drive the second mounting bracket 4171 to move towards the pre-opening cover position 51. Thus, the third elastic member 4174 can reduce the driving unit required for the sliding of the first cover opening device 41, so as to reduce the cost of the first cover opening device 41 and the entire sample analysis equipment.

[0173] The third elastic member 4174 can be a torsion spring, a compression spring, a disc spring, or the like, and the embodiments of the present application do not limit the third elastic member 4174.

[0174] In some embodiments, the pressing assembly 417 further includes a first reset member 4175. The first reset member 4175 is arranged on the second mounting bracket 4171, and the first reset member 4175 is located on the path of the sliding of the first mounting bracket 411 away from the pre-opening cover position 51, so that when the first mounting bracket 411 moves away from the pre-opening cover position 51, the first reset member 4175 can drive the second mounting bracket 4171 to move away from the pre-opening cover position 51.

[0175] For example, the first reset member 4175 can include a reset rod mounted on the first mounting bracket 411 and located on the side of the first mounting bracket 411 away from the pre-opening cover position 51.

[0176] Therefore, on one hand, when the first mounting frame 411 moves away from the pre-cover opening position 51, the first mounting frame 411 pushes the first reset member 4175 and the second mounting frame 4171 connected thereto to move away from the pre-cover opening position 51. On the other hand, when the first mounting frame 411 moves towards the pre-cover opening position 51, the third elastic member 4174 can drive the second mounting frame 4171 to move towards the pre-cover opening position 51.

[0177] In some embodiments, the pressing assembly 417 further comprises a fourth elastic member 4176. The fourth elastic member 4176 is mounted to the first mounting seat 415, and is configured to drive the second mounting frame 4171 to move away from the pre-cover opening position 51. The fourth elastic member 4176 has a smaller elastic coefficient than the third elastic member 4174.

[0178] Therefore, even if the second driving unit 416 is accidentally powered off during the operation of the sample analyzer, and the third elastic member 4174 drives the second mounting frame 4171 to slide towards the pre-cover opening position 51, the fourth elastic member 4176 can provide a buffer to prevent the first mounting frame 411 from rapidly moving to the pre-cover opening position 51 and colliding with the reagent bottle at the pre-cover opening position 51.

[0179] For reference Figure 12 and Figure 13 Based on the above structure, a cover opening process of the first cover opening device 41 can be as follows:

[0180] Step 1: Place the reagent bottle at the pre-cover opening position 51.

[0181] Step 2: The second driving unit 416 drives the first mounting frame 411 to move towards the pre-cover opening position 51. At the same time, the third elastic member 4174 drives the second mounting frame 4171 to move towards the pre-cover opening position 51, and the second elastic member 4173 drives the pressing part 4172b of the pressing member 4172 to rotate towards the pre-cover opening position 51, so that the pressing part 4172b of the pressing member 4172 presses the bottle body 100 of the reagent bottle.

[0182] Step 3: The second driving unit 416 continues to drive the first mounting frame 411 to move towards the pre-cover opening position 51, so that the shielding member 22 of the reagent bottle is located between the pushing member 413 and the buffer assembly 414.

[0183] Fourthly, the first driving unit 412 drives the pusher 413 to push the shielding member 22 of the reagent bottle upwards to unseal the bottle mouth 121 (or the liquid suction hole 211) of the reagent bottle, and the buffer assembly 414 provides a buffer for the shielding member 22 to avoid the reagent in the reagent bottle from splashing out due to the shaking of the reagent bottle when the shielding member 22 unseals the bottle mouth 121 (or the liquid suction hole 211).

[0184] Fifthly, the first driving unit 412 continues to drive the pusher 413 to push the shielding member 22 of the reagent bottle upwards, so that the first rotating member 4141 and the second rotating member 4142 of the buffer assembly 414 are in contact.

[0185] Sixthly, the first driving unit 412 continues to drive the pusher 413 to push the shielding member 22 of the reagent bottle upwards, so that the shielding member 22 rotates to a first preset angle. At this time, the second rotating member 4142 drives the first rotating member 4141 to rotate away from the pusher 413, so that the first rotating member 4141 and the pusher 413 switch from the state of clamping the shielding member 22 to the state of releasing the shielding member 22.

[0186] Seventhly, the second driving unit 416 drives the first mounting frame 411 to move away from the pre-cap opening position 51, and the first mounting frame 411 drives the second mounting frame 4171 to move away from the pre-cap opening position 51 through the first return member 4175, so that the first cap opening device 41 realizes avoidance; then, the shielding member 22 can rotate to a micro-closed state under the drive of the first elastic member 23.

[0187] Eighthly, the first driving unit 412 drives the pusher 413 to reset, and the pusher 413 drives the buffer assembly 414 to reset.

[0188] For reference Figure 14 Based on the above structure, a process of driving the shielding member 22 to seal the bottle mouth 121 (or the liquid suction hole 211) of the first cap opening device 41 can be as follows:

[0189] Firstly, the reagent bottle is placed on the pre-cap opening position 51, and the first driving unit 412 drives the pusher 413 to rotate towards the direction of pushing the shielding member 22 to expose the liquid suction hole 211.

[0190] Secondly, the second driving unit 416 drives the first mounting frame 411 to move towards the pre-cap opening position 51; at the same time, the third elastic member 4174 drives the second mounting frame 4171 to move towards the pre-cap opening position 51, and the second elastic member 4173 drives the pressing part 4172b of the pressing member 4172 to move towards the pre-cap opening position 51, so that the pressing part 4172b of the pressing member 4172 presses the bottle body 100 of the reagent bottle.

[0191] In the third step, the second driving unit 416 continues to drive the first mounting frame 411 to move towards the direction of the pre-cover opening position 51, so that the shielding part 22 of the reagent bottle is located at the lower side of the pushing part 413.

[0192] In the fourth step, the first driving unit 412 drives the pushing part 413 to push the shielding part 22, so that the shielding part 22 is rotated to the second sealing part 221 is inserted into the liquid suction hole 211 to seal the liquid suction hole 211, thereby realizing the sealing of the bottle mouth 121.

[0193] The above is some explanation and description of the first cover opening device 41 in the embodiments of the present application. The technical solutions of the embodiments of the present application will be described below in combination with the second cover opening device 42.

[0194] As mentioned above, the shielding part 22 can also include the first operation part 223, and the first operation part 223 and the second operation part 222 are protruded from the opposite sides of the cover body 21. Therefore, the second cover opening device 42 can be used to push the first operation part 223 of the shielding part 22 to drive the shielding part 22 to rotate.

[0195] Please refer to Figure 15 and Figure 16 In some embodiments, the second cover opening device 42 includes a third mounting frame 421, a third driving unit 422 and a pressing assembly 423. The third driving unit 422 is mounted on the third mounting frame 421. The pressing assembly 423 is in transmission connection with the third driving unit 422, so that the third driving unit 422 can drive the pressing assembly 423 to push the shielding part 22, for example, to push the first operation part 223 of the shielding part 22 to rotate towards the cover body 21.

[0196] The third driving unit 422 can be a motor, a cylinder or the like, and the embodiments of the present application do not limit the third driving unit 422.

[0197] In some embodiments, the pressing assembly 423 includes at least two pressing parts 4231, and at least part of the pressing parts 4231 are used to push the first operation part 223 of different reagent bottles. Therefore, the second cover opening device 42 can complete the cover opening operation of at least two reagent bottles at one time, so as to improve the working efficiency of the second cover opening device 42 and the whole sample analysis equipment.

[0198] In some embodiments, the second uncovering device 42 further comprises a second mounting base 424 and a fourth driving unit 425. The second mounting base 424 is movably connected with the third mounting frame 421. The fourth driving unit 425 is mounted on the second mounting base 424 or the third mounting frame 421, and is configured to drive the third mounting frame 421 to move, so that the third mounting frame 421 drives the pressing assembly 423 to push the shielding member 22 to move towards the liquid suction hole 211.

[0199] In some embodiments, the third mounting frame 421 can be rotatably mounted on the second mounting base 424. The second mounting base 424 is provided with a first gear. The fourth driving unit 425 comprises a motor mounted on the third mounting frame 421, and the motor output shaft of the fourth driving unit 425 is provided with a second gear. The second gear is engaged with the first gear.

[0200] Therefore, the second gear and the first gear can constitute a planetary gear pair. When the fourth driving unit 425 drives the second gear to rotate, the second mounting base 424 can be fixed, and the fourth driving unit 425 and the second gear rotate around the circumference of the first gear.

[0201] In some embodiments, the first mounting base 415 and the second mounting base 424 can be fixed on the rack 500.

[0202] Please continue to refer to Figure 17 Based on the above structure, a working process of the second uncovering device 42 can be as follows:

[0203] In the first step, the third driving unit 422 drives the pressing assembly 423 to move downwards, so that the pressing assembly 423 pushes the first operating part 223 of the shielding member 22 of the reagent bottle to rotate downwards, so that the shielding member 22 is rotated to expose the liquid suction hole 211, so as to provide the pipette device 43 to suck the reagent carried in the reagent bottle.

[0204] In the second step, the third driving unit 422 drives the pressing assembly 423 to move upwards, and the fourth driving unit 425 drives the third mounting frame 421 and the pressing assembly 423 to rotate forward, so that the pressing assembly 423 rotates upwards, thereby pushing the shielding member 22 to move towards the liquid suction hole 211.

[0205] In the third step, the third driving unit 422 continues to drive the pressing assembly 423 to move upwards, and the fourth driving unit 425 continues to drive the third mounting frame 421 and the pressing assembly 423 to rotate forward, so that the pressing assembly 423 continues to rotate upwards to push the shielding member 22 to rotate to an opening angle less than the first preset value, and then the first elastic member 23 also synchronously drives the shielding member 22 to rotate to a micro-closed state.

[0206] In the fourth step, the fourth driving unit 425 continues to drive the pressing assembly 423 to move upward to reset, and the fourth driving unit 425 drives the third mounting frame 421 and the pressing assembly 423 to rotate reversely and reset.

[0207] In the above embodiments, the description of each embodiment has its own focus, and the parts not described in detail in a certain embodiment can be referred to the relevant description of other embodiments.

[0208] The reagent bottle and the sample analysis device provided by the embodiments of the present application are described in detail above, and the principles and implementation manners of the present application are described by applying specific examples. The above embodiment descriptions are only used to help understand the method of the present application and its core idea. Meanwhile, for those skilled in the art, the specific implementation manners and application ranges will be changed according to the idea of the present application. In summary, the content of the specification should not be understood as a limitation of the present application.

Claims

1. A reagent bottle, characterized in that, include: The bottle body is a blow-molded part, and the bottle body is provided with a bottle mouth; and, A bottle cap, which is an injection-molded part, includes a cap body and a shielding member. The cap body is detachably connected to the bottle body to cover the bottle opening. The cap body has a liquid suction hole that communicates with the bottle opening. The shielding member is hinged to the cap body. The shielding member can rotate to block the liquid suction hole so that the bottle cap seals the bottle opening. The shielding member can also rotate to expose the liquid suction hole so that an external device can draw the reagent contained in the reagent bottle through the liquid suction hole.

2. The reagent bottle according to claim 1, characterized in that, The bottle body and the cap body are threaded together.

3. The reagent bottle according to claim 2, characterized in that, The bottle body is provided with a first limiting member, and the bottle cap is provided with a second limiting member. The first limiting member is used to abut against the second limiting member to limit the travel of the cap body in the tightening direction.

4. The reagent bottle according to claim 3, characterized in that, The bottle cap is also provided with a third limiting member, which is used to abut against the first limiting member to limit the travel of the cap in the unscrewing direction.

5. The reagent bottle according to claim 4, characterized in that, The third limiting member includes: A contact surface, the contact surface being used to abut against the first limiting member to restrict the cover from rotating along the loosening direction; and, A guide ramp is connected to the abutment surface and is located on one side of the abutment surface along the loosening direction. The guide ramp is used to guide the first limiting member to move to the side where the abutment surface of the third limiting member is located during the tightening process of the cover.

6. The reagent bottle according to claim 4, characterized in that, The third limiting member and the second limiting member are spaced apart in the circumferential direction of the cover to create space for engaging the first limiting member; and / or, The bottle body includes a main body and a bottle mouth. The bottle mouth and the first limiting member protrude from the same side of the main body. The bottle mouth is formed at the end of the bottle mouth away from the main body. The outer periphery of the bottle mouth is provided with an external thread for threaded connection with the cap.

7. The reagent bottle according to claim 2, characterized in that, The cap includes a first top wall and a first side wall. The first side wall is connected to the outer periphery of the first top wall and is threaded to the bottle body so that the first top wall covers the bottle mouth. The cover further includes at least one of a first sealing part and a third sealing part; The first sealing part protrudes from the side of the first top wall away from the bottle opening, and the liquid absorption hole is formed on the inner peripheral surface of the first sealing part. The inner peripheral surface of the first sealing part is press-fitted with the shielding member to seal the liquid absorption hole. The third sealing part protrudes from the side of the first top wall facing the bottle opening, and the outer peripheral surface of the third sealing part is interference-fitted with the inner peripheral surface of the bottle opening to seal the bottle opening.

8. The reagent bottle according to any one of claims 1 to 7, characterized in that, The bottle cap also includes a hinge, which is connected to both the cap body and the shielding member, so that the cap body and the shielding member are hinged together.

9. The reagent bottle according to claim 8, characterized in that, The shielding member includes a shielding part and a first operating part connected together. The shielding part is used to shield the liquid absorption hole. The first operating part protrudes from the side of the hinge in the circumferential direction of the cap body. The first operating part can receive external force and rotate in the direction closer to the bottle body to drive the shielding part to rotate to expose the liquid absorption hole.

10. The reagent bottle according to claim 8, characterized in that, At least one of the bottle body and the bottle cap is provided with a first elastic element; When the opening angle of the blocking member is less than a first preset value, the first elastic member can drive the blocking member to block the liquid absorption hole. The opening angle of the blocking member is the angle between the blocking member and the plane where the opening of the liquid absorption hole is located. When the opening angle of the shielding member is greater than the first preset value, the first elastic member can drive the shielding member to expose the liquid absorption hole.

11. The reagent bottle according to claim 10, characterized in that, The outer periphery of the cover is provided with a second connecting portion; both the hinge and the first elastic member are connected between the second connecting portion and the shielding member; and / or The number of hinges is two, and the first elastic element is located between the two hinges.

12. The reagent bottle according to any one of claims 1 to 7, characterized in that, The bottle body is made of polyethylene, and the bottle cap is made of polypropylene.

13. A reagent bottle, characterized in that, include: Bottle body, wherein the bottle body is provided with a bottle mouth; and, A bottle cap, which is a one-piece molded plastic part, includes a cap body, a blocking member, and a first elastic member. The cap body is detachably connected to the bottle body to cover the bottle opening. The cap body has a liquid suction hole that communicates with the bottle opening. The blocking member is movably connected to the cap body. The blocking member can move to block the liquid suction hole, so that the bottle cap seals the bottle opening, and the blocking member can also move to expose the liquid suction hole, so that an external device can draw liquid from the bottle body through the liquid suction hole. When the opening angle of the blocking member is less than a first preset value, the first elastic member can drive the blocking member to block the liquid suction hole. The opening angle of the blocking member is the angle between the blocking member and the plane where the opening of the liquid suction hole is located. When the opening angle of the blocking member is greater than the first preset value, the first elastic member can drive the blocking member to expose the liquid suction hole.

14. The reagent bottle according to claim 13, characterized in that, The bottle cap also includes a hinge, which is connected to both the cap body and the shielding member, so that the cap body and the shielding member are hinged. The cover has a second connecting portion protruding from its outer periphery, and both the hinge and the first elastic member are connected between the second connecting portion and the shielding member; and / or, there are two hinges, and the first elastic member is located between the two hinges.

15. A sample analysis device, characterized in that, include: A reagent containing mechanism for containing a reagent bottle as described in any one of claims 1 to 14; and, The reagent dispensing mechanism includes an opening and closing cap device and a pipetting device. The opening and closing cap device is used to drive the blocking member to move so as to block or expose the suction hole. The pipetting device is used to draw the reagent carried in the bottle through the suction hole and transfer it to the reaction vessel.

Images