Special sample extraction test tube for calprotectin

Abstract

The utility model discloses a special sample extraction test tube for calprotectin, which comprises a tube body with two open ends; the sampling rod is coaxially inserted into the pipe body, and the tail end of the sampling rod extends out of one end of the pipe body and is detachably connected with the end; the tube cover is detachably connected with the other end of the tube body, the tube cover comprises a first cover body and a second cover body, filter cotton is arranged in the first cover body, the second cover body is detachably arranged on the first cover body, and a dripping hole is formed in the top of the first cover body. According to the sample extraction test tube, the first cover body and the second cover body which are detachably arranged as well as the filter cotton arranged on the first cover body are adopted, so that the sample extraction test tube has the characteristics of different detection instruments, medical personnel do not need to prepare different sample extraction devices for different instruments, and the complexity and the cost of operation are reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field, more specifically, the utility model relates to a sample extraction test tube special for calprotectin. BACKGROUND

[0002] In the field of medical instrument detection reagent, the accurate detection of calprotectin sample is of great significance to disease diagnosis, and the sample extraction link is crucial. Calprotectin mainly exists in samples such as feces and urine. After sampling with a sampling rod, the sampling rod is inserted into the sampling tube, and then the tube body is shaken to mix the sample with the reagent in the tube body to form a mixed solution, and then the instrument is used for detection.

[0003] The traditional sample extraction test tube for sampling calprotectin includes a tube body with two open ends, a sampling rod inserted into the tube body, and the end of the sampling rod is detachably sealed with the open end of the tube body. The other end of the tube body is screwed with a tube cover, as shown in Figure 1 The sample extraction test tube is suitable for full-automatic instrument detection (with screw cover function and impurity filtering mechanism).

[0004] However, when this sample extraction test tube is used for semi-automatic instrument detection, obvious problems are exposed. The semi-automatic instrument needs manual liquid dropping operation. If the sharp end at the top of the tube cover is twisted off in the traditional way, although the manual liquid dropping can be completed, the overall structure of the tube cover is damaged and cannot be used again. If the tube cover is still opened by screwing, since the semi-automatic instrument lacks the sample pretreatment capability of the full-automatic instrument, the filter cotton cannot effectively filter the mixed solution, and the impurities in the mixed solution may block the detection instrument, affecting the normal detection. Moreover, the impurities may interfere with the detection signal, causing the detection result to deviate, which cannot accurately reflect the real content of calprotectin in the sample, and further affects the accurate diagnosis of the disease by the doctor.

[0005] In actual clinical detection, the equipment configuration of different hospitals or detection agencies is quite different, including full-automatic detection instruments and semi-automatic detection instruments. The single sample dropping structure of the traditional sample extraction test tube cannot meet the needs of different detection instruments, which means that medical staff need to prepare different sample extraction devices for different instruments, increasing the complexity and cost of operation. This situation urgently needs a new sample extraction test tube design that can take into account the characteristics of different detection instruments and provide more convenient and accurate sample processing and detection methods. SUMMARY

[0006] An object of the utility model is to provide a sample extraction test tube special for calprotectin, comprising:

[0007] The tube body is provided with two open ends;

[0008] A sampling rod is coaxially inserted into the tube body, and an end of the sampling rod extends from one end of the tube body and is detachably connected to the end;

[0009] A tube cover is detachably connected to the other end of the tube body, the tube cover comprises a first cover body with filter cotton inside, and a second cover body detachably arranged on the first cover body, and a drip hole is arranged on the top of the first cover body.

[0010] Preferably, the first cover body is internally provided with a first thread;

[0011] The outer side of one end of the tube body is provided with a second thread matched with the first thread, and the first thread is threadedly connected with the second thread.

[0012] Preferably, the top of the first cover body is externally provided with a third thread;

[0013] The inner side of the second cover body is provided with a fourth thread matched with the third thread, and the third thread is threadedly connected with the fourth thread, and the second cover body completely covers the drip hole.

[0014] Preferably, the inner wall of the first cover body is provided with an annular protrusion, and the filter cotton is clamped on the annular protrusion.

[0015] Preferably, the end of the sampling rod detachably connected with the tube body is provided with a sealing rubber ring, and the sealing rubber ring is tightly attached to the inner wall of the tube body.

[0016] Preferably, the outer side of the second cover body is provided with anti-skid corrugations, the anti-skid corrugations are uniformly distributed along the circumference of the second cover body, and the surface of the anti-skid corrugations is provided with a hydrophobic coating.

[0017] Preferably, the outer wall of the tube body is provided with a scale mark.

[0018] Preferably, the drip hole of the first cover body is provided with an anti-blocking structure, and the anti-blocking structure is a conical flow guide surface recessed inward.

[0019] Preferably, the filter cotton comprises a surface dense layer on one side close to the drip hole and a deep loose layer on one side close to the inner cavity of the tube body, and the pore size of the deep loose layer is larger than that of the surface dense layer.

[0020] The utility model at least has following beneficial effects:

[0021] Firstly, the first cover body and the second cover body are detachably arranged, and the filter cotton is arranged on the first cover body, so that the sample extraction test tube takes into account the characteristics of different detection instruments, medical staff do not need to prepare different sample extraction devices for different instruments, and the complexity and cost of operation are reduced.

[0022] Secondly, the utility model discloses a second cover body's outside is provided with anti -skid corrugation and is provided with the hydrophobic coating on the surface of anti -skid corrugation, help to avoid because the hand has the liquid and hand slip and cause the second cover body falls or sample spills, simultaneously, the hydrophobic characteristic makes liquid difficult to remain on the second cover body surface, reduced the risk of sample cross -contamination, guaranteeed the accuracy of detection result.

[0023] Other advantages, objects and features of the present utility model will be partly embodied by the following description, and some will be understood by the skilled in the art through the study and practice of the present utility model. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 It is the side view of traditional sample extraction test tube;

[0025] Figure 2 It is the side view of the sample extraction test tube of one of the technical schemes of the present utility model;

[0026] Figure 3 It is the side view of the pipe body of one of the technical schemes of the present utility model;

[0027] Figure 4 It is the side surface structure schematic view of the first cover body of one of the technical schemes of the present utility model;

[0028] Figure 5 It is the side surface sectional view of the first cover body of one of the technical schemes of the present utility model.

[0029] In the drawings, the marks are as follows:

[0030] 1, pipe body;2, sampling rod;3, pipe cover;4, first cover body;5, second cover body;6, scale mark;7, first screw thread;8, second screw thread;9, annular protrusion;10, anti -clogging structure. DETAILED DESCRIPTION

[0031] The present utility model will be further described in detail below in conjunction with the drawings, so that the skilled person can implement according to the description.

[0032] It should be noted that the experimental methods in the following implementation solutions are all conventional methods, and the reagents and materials can be obtained from commercial channels unless otherwise specified;In the description of the present utility model, the orientation or positional relationship indicated by the terms is based on the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present utility model and simplifying the description, and does not indicate or imply that the indicated device or element must have a particular orientation, structure and operation, so it cannot be understood as a limitation on the present utility model.

[0033] As Figures 1-5 shown, the utility model provides a sample extraction test tube special for calprotectin, include:

[0034] The pipe body 1 is provided with openings at both ends, specifically, the pipe body 1 is provided with openings at both ends, is hollow cylindrical, and the material can select medical grade plastics, has good chemical stability and mechanical strength;

[0035] The sampling rod 2 is coaxially inserted into the pipe body 1, and the tail end of the sampling rod 2 extends from one end of the pipe body 1 and is detachably connected to the end, specifically, the shape of the sampling rod 2 is matched with the inner wall of the pipe body 1, which can avoid the sampling rod 2 from being greatly deviated when the pipe body 1 is shaken, the tail end of the sampling rod 2 extends from one end of the pipe body 1 and is detachably connected to the end, and the specific connection mode can be threaded connection, that is, the tail end of the sampling rod 2 is provided with external threads, and the inner wall of the end of the pipe body 1 is provided with internal threads, so that medical staff can easily screw the sampling rod 2 into or out of the pipe body 1 when using, which is convenient for sampling and sample transfer, after the sampling rod 2 is used to collect samples such as feces and urine, the sampling rod 2 is inserted into the pipe body 1, reagents are added from the other end of the pipe body 1, and then the pipe body 1 is shaken to mix the sample and the reagents in the pipe body 1 to form a mixed solution;

[0036] The pipe cover 3 is detachably connected to the other end of the pipe body 1, the pipe cover 3 includes a first cover body 4 provided with filter cotton inside, and a second cover body 5 detachably arranged on the first cover body 4, and the top of the first cover body 4 is provided with a dripping hole, specifically, the filter cotton inside the first cover body 4 is made of medical grade filter material, and the pore size is specially designed to effectively intercept impurities in the mixed solution while ensuring that the target detection substances such as calprotectin pass smoothly.

[0037] In the above technical solution, when a semi-automatic instrument is needed for manual liquid drop detection, medical staff can directly detach the second cover body 5 and perform liquid drop operation through the dripping hole at the top of the first cover body 4, and since the filter cotton is present, impurities in the mixed solution are effectively filtered, avoiding the problem of impurities blocking the detection instrument and interfering with the detection signal, and ensuring the accuracy of the detection result; when a fully automatic instrument is used for detection, the second cover body 5 does not need to be detached, the structure of the whole pipe cover 3 is retained, and the cap rotating function and impurity filtering mechanism of the fully automatic instrument cooperate with the first cover body 4 (the size is matched with the cap rotating mechanism of the fully automatic instrument), the fully automatic instrument automatically rotates the first cover body 4, and the detection process is smoothly carried out, which takes into account the characteristics of different detection instruments, and medical staff do not need to prepare different sample extraction devices for different instruments, reducing the complexity and cost of operation.

[0038] In another technical solution, the first cover 4 is internally provided with a first thread 7;

[0039] The outer side of one end of the tube body 1 is provided with a second thread 8 matched with the first thread 7, and the first thread 7 is threadedly connected with the second thread 8; specifically, the first cover 4 is internally provided with the first thread 7, and the outer side of one end of the tube body 1 is provided with the second thread 8 matched with the first thread 7, and the first thread 7 and the second thread 8 are designed in a fine thread, which can ensure tight connection and facilitate manual screwing operation of medical staff.

[0040] In another technical solution, the top outer side of the first cover 4 is provided with a third thread;

[0041] The inner side of the second cover 5 is provided with a fourth thread matched with the third thread, and the third thread is threadedly connected with the fourth thread, and the second cover 5 completely covers the drip hole; specifically, the third thread and the fourth thread are designed in a fine thread, which can ensure tight connection and facilitate manual screwing operation of medical staff to unscrew or tighten the second cover 5 from the first cover 4.

[0042] In another technical solution, the inner wall of the first cover 4 is provided with an annular protrusion 9, and the filter cotton card is arranged on the annular protrusion 9; specifically, the annular protrusion 9 is made by an integral molding process and is synchronously injection molded with the first cover 4, and has the same material as the first cover 4, i.e. medical-grade polypropylene, so as to ensure that no harmful substances are released to pollute the sample during sample detection, the annular protrusion 9 is arranged along the inner wall of the first cover 4 in a circumferential direction, and has a trapezoidal cross section, which can not only ensure stable support of the filter cotton, but also facilitate installation and disassembly of the filter cotton.

[0043] In another technical solution, the end of the sampling rod 2 sealingly and detachably connected with the tube body 1 is provided with a sealing rubber ring, and the sealing rubber ring is tightly attached to the inner wall of the tube body 1; specifically, in order to further improve the sealing performance of the sample and the reliability of the detection process, the end of the sampling rod 2 sealingly and detachably connected with the tube body 1 is provided with the sealing rubber ring, and the sealing rubber ring is made of medical-grade silicone rubber material, which has excellent chemical stability, can resist various acid and alkali substances possibly existing in the sample, meets the biological compatibility standard of medical devices, will not cause adsorption or chemical reaction of detection substances such as calprotectin in the sample, ensures the stability of the sample composition, effectively prevents leakage of the sample mixed solution from the connection part, and avoids entry of external air, moisture and microorganisms into the tube body 1, so as to prevent the sample from being polluted or deteriorated.

[0044] In another technical solution, the outer side of the second cover 5 is provided with anti-skid corrugations, which are uniformly distributed circumferentially along the second cover 5, and the surface of the anti-skid corrugations is provided with a hydrophobic coating; specifically, the anti-skid corrugations are integrally formed with the second cover 5 by using a high-precision injection molding process, which can significantly increase the friction between the fingers and the second cover 5, facilitating daily use and maintenance. The hydrophobic coating is uniformly covered on the surface of the anti-skid corrugations by using a nano-scale fluoropolymer material through a spraying process. The hydrophobic coating has excellent hydrophobic properties, which can effectively prevent sample mixed liquid, water stains and other liquids from adhering to the surface of the second cover 5. In actual operation, when medical staff hold the second cover 5 to perform unscrewing or tightening operations, even if there is a small amount of liquid on the hands, the double effect of the anti-skid corrugations and the hydrophobic coating can ensure stable holding, avoiding the second cover 5 from falling or the sample from spilling due to slippery hands. At the same time, the hydrophobic property makes it difficult for liquid to remain on the surface of the second cover 5, reducing the risk of sample cross-contamination and ensuring the accuracy of the test results.

[0045] In another technical solution, the outer wall of the tube body 1 is provided with a scale mark 6; specifically, the scale mark 6 is made by using a laser engraving process to engrave clear and permanent lines and numbers directly on the medical-grade plastic outer wall of the tube body 1. During the sample collection stage, medical staff can accurately control the volume of the collected sample according to the scale mark 6 to ensure the consistency of the sample amount for each test. In the reagent adding link, reagents can also be accurately added according to the scale to fully and accurately mix the sample and the reagent to form a mixed liquid that meets the detection requirements.

[0046] In another technical solution, the drop hole of the first cover 4 is provided with an anti-blocking structure 10, which is a inwardly recessed conical flow guide surface; specifically, the conical flow guide surface is integrally formed with the first cover 4 by using an integrated molding process, and the conical angle of the conical flow guide surface is optimized by fluid mechanics to effectively guide the sample mixed liquid to converge towards the drop hole, reducing the residue and accumulation of liquid around the drop hole. Through the guidance of the flow guide surface, the liquid can flow smoothly to the drop hole. In the process of manual liquid dropping by semi-automatic instruments, the inwardly recessed conical flow guide surface can use gravity and liquid surface tension to concentrate and guide the mixed liquid to the drop hole, avoiding blockage caused by impurities or liquid adhering to the edge of the drop hole. At the same time, the smooth surface of the flow guide surface further reduces the resistance of liquid flow, so that the mixed liquid can flow more smoothly through the drop hole, improving the efficiency of liquid dropping.

[0047] In another technical solution, the filter cotton comprises a surface dense layer close to one side of the drop hole, and a deep loose layer close to one side of the inner cavity of the tube body 1, the pore size of the deep loose layer is larger than that of the surface dense layer; specifically, the filter cotton as a whole is made of medical-grade nylon fiber through a special process, and has good flexibility and mechanical strength, and can maintain a stable structure during the filtering process, wherein the pore size of the deep loose layer can be set to 40-60 μm, and the loose porous structure thereof is like a "first line of defense", when the sample mixture flows from the inner cavity of the tube body 1 to the drop hole, the deep loose layer can quickly intercept larger particulate impurities in the fecal sample, such as undigested food fibers, cell clumps, etc., such a large-pore, loose design greatly reduces the resistance when the mixture passes through, so that the liquid can quickly penetrate, avoiding a large amount of accumulation in the first cover body 4, ensuring the filtering efficiency, and the surface dense layer close to the drop hole has a pore size accurately controlled at 5-10 μm, and the dense fiber arrangement forms a "second fine filter screen", the mixture filtered by the deep loose layer can be further intercepted by the surface dense layer when penetrating to the drop hole, so that micro-particles, bacteria and other impurities are prevented from entering the drop hole with the mixture, thereby preventing the detection instrument from being blocked or the detection signal from being disturbed, and the fine structure of this layer can still make the mixture containing calprotectin pass through smoothly to the detection instrument by means of the liquid surface tension and pressure difference, when a semi-automatic instrument is used for manual liquid dropping operation, thanks to the layered structure of the filter cotton, medical staff can observe that the mixture is stably and continuously dropped from the drop hole, without worrying about the interruption or poor flow of the liquid dropping caused by the impurities blocking.

[0048] Although the embodiments of the present application have been disclosed as above, it is not limited to the application listed in the specification and the embodiments, and can be fully applied to various fields suitable for the present application. For those skilled in the art, other modifications can be easily realized, and therefore the present application is not limited to specific details and the figures shown and described herein, without departing from the general concept defined by the claims and the equivalent scope.

Claims

1. A sample extraction tube dedicated for calprotectin, characterized in that, The utility model relates to a sampling device, comprising: a tube body with both ends open; a sampling rod coaxially inserted into the tube body, with one end of the sampling rod extending from one end of the tube body and detachably connected to the end; a tube cover detachably connected to the other end of the tube body, the tube cover comprising a first cover body with filter cotton inside, a second cover body detachably arranged on the first cover body, and a drip hole provided on the top of the first cover body.

2. The calprotectin-specific sample extraction test tube according to claim 1, characterized in that, The inside of the first cover body is provided with a first thread; the outside of one end of the tube body is provided with a second thread matched with the first thread, and the first thread is threadedly connected with the second thread.

3. The calprotectin specific sample extraction test tube of claim 2, wherein, The top outside of the first cover body is provided with a third thread; the inside of the second cover body is provided with a fourth thread matched with the third thread, and the third thread is threadedly connected with the fourth thread, and the second cover body completely covers the drip hole.

4. The calprotectin-specific sample extraction test tube according to claim 2, wherein The inner wall of the first cover body is provided with an annular protrusion, and the filter cotton is clamped on the annular protrusion.

5. The calprotectin-specific sample extraction test tube according to claim 4, wherein The end of the sampling rod detachably connected with the tube body is provided with a sealing rubber ring, and the sealing rubber ring is tightly attached to the inner wall of the tube body.

6. The calprotectin-specific sample extraction test tube of claim 1, wherein, The outside of the second cover body is provided with anti-skid corrugations, which are uniformly distributed along the circumference of the second cover body, and the surface of the anti-skid corrugations is provided with a hydrophobic coating.

7. The calprotectin-specific sample extraction test tube of claim 1, wherein, The outer wall of the tube body is provided with a scale mark.

8. The calprotectin-specific sample extraction test tube of claim 1, wherein, The drip hole of the first cover body is provided with an anti-blocking structure, which is a conical flow guide surface inwardly recessed.

9. The calprotectin-specific sample extraction test tube of claim 1, wherein, The filter cotton comprises a surface dense layer on one side close to the drip hole and a deep loose layer on one side close to the inner cavity of the tube body, and the pore size of the deep loose layer is larger than that of the surface dense layer.

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