Mouse caudal vein blood sampling fixing device

Abstract

The utility model relates to the technical field of animal experiment equipment, in particular to a mouse caudal vein blood sampling fixing device which comprises a base and a sleeve arranged on the base, the sleeve comprises a fixed section and a sliding section, a sliding cavity is formed in the fixed section, the sliding section is arranged in the sliding cavity in a sliding mode, and a locking limiting piece is arranged at the end of the sliding section. A plurality of limiting holes used for being matched with the locking limiting pieces are formed in the wall of the sliding cavity, and the limiting holes are formed in the axial direction of the fixing section. The base is provided with a graduated scale for measuring the length of a mouse body, and the rear end is provided with a light source. The length of the sleeve can be adjusted according to the size of a mouse, the tail of the mouse extends out of the tail hole after the mouse is fixed in the sleeve, a light source penetrates through caudal veins of the mouse, visual blood sampling is facilitated, and the light source can improve the accuracy and success rate of blood sampling; and meanwhile, the sliding sleeve solves the problems of tedious operation steps and long consumed time due to the fact that a fixed cylinder needs to be rotated for multiple times when the length of an existing mouse fixing device is adjusted.

Description

Technical Field

[0001] This utility model relates to the field of animal experimental equipment technology, specifically a mouse tail vein blood collection and fixation device. Background Technology

[0002] In animal experiments, tail vein injection and blood collection in mice are common procedures that require the mice to be immobilized. However, the traditional method of manual immobilization has many drawbacks. On the one hand, manual immobilization can easily irritate the mice and increase the risk of injury to the operator. On the other hand, it is labor-intensive and inefficient when dealing with a large number of mice.

[0003] To address the aforementioned issues, existing technology CN219846954U provides a device for tail vein injection and blood collection in mice, comprising a worktable with a head fixing cylinder, a body fixing cylinder, and a tail fixing plate. The rear end of the head fixing cylinder and the front end of the body fixing cylinder are slidably connected axially. The body fixing cylinder is divided into upper and lower parts: the part connected to the worktable is the fixing part, and the upper part is the adjusting part. The adjusting part and the fixing part are circumferentially connected. The head fixing cylinder and the body fixing cylinder of this device can achieve a certain length adjustment axially. During use, movement and locking are achieved through the cooperation of a positioning pin, a limiting groove, and a locking groove.

[0004] However, in practice, this adjustment method has the following technical problems: Each time the length is adjusted, the head-fixing cylinder must first be rotated to position the locating pin within the limiting groove, then the head-fixing cylinder must be moved to the appropriate position and rotated again to lock the locating pin in the groove. This requires multiple rotations of the head-fixing cylinder, making the operation cumbersome and time-consuming. This is especially problematic when experiments require frequent changes of mice of different body lengths, severely impacting experimental efficiency. Furthermore, if the length of the fixing cylinder is adjusted after the mouse has been inserted, the mouse will rotate along with it, causing it to be startled. If the length is adjusted before inserting the mouse, the length may be improperly adjusted, resulting in the mouse being either too tight or too loose, hindering the smooth progress of the experiment. Utility Model Content

[0005] This invention provides a mouse tail vein blood collection fixation device, which can solve the technical problem that existing fixation devices require multiple rotations of the fixation cylinder when adjusting the length, resulting in cumbersome operation steps and long time consumption.

[0006] This application provides the following technical solution:

[0007] A mouse tail vein blood collection and fixation device includes a base and a sleeve disposed on the base. The sleeve includes a fixed section and a sliding section. A sliding cavity is provided in the fixed section. The sliding section is slidably disposed in the sliding cavity, and a locking limit member is provided at the end of the sliding section. A plurality of limiting holes for cooperating with the locking limit member are provided on the wall of the sliding cavity. The limiting holes are arranged along the axial direction of the fixed section. A conical mesh structure is provided at the front end of the sliding section, and a sealing cap is provided at the rear end of the fixed section. A tail hole is provided on the sealing cap.

[0008] Beneficial effects:

[0009] 1. By sliding the sliding section to the fixed section, when the length of the sleeve needs to be adjusted, simply push or pull the sliding section to make it contract or expand relative to the fixed section. After adjustment to a certain position, the locking limit piece of the sliding section automatically engages with the limiting hole to lock and limit the sliding section, preventing the sliding section from loosening due to the movement of the mouse inside the sleeve. This adjustment method does not require multiple rotations of the sleeve, making the operation simpler and more convenient, saving adjustment time and improving operational efficiency.

[0010] 2. Because the adjustment is done by pushing and pulling, compared with the existing method of first rotating, then pushing and pulling, and finally rotating again for positioning, this method causes less interference to the mice, avoids startling the mice due to large-scale adjustment, and is conducive to subsequent experiments.

[0011] 3. By setting a conical mesh structure at the front end of the sliding section, the mouse's head can be restricted on the one hand, and the mesh structure facilitates the mouse's breathing on the other hand; the sealing cap at the rear end of the fixed section is used to seal the tail end of the sleeve, and the mouse's tail protrudes from the tail hole, which facilitates the venous blood collection operation from the tail.

[0012] Furthermore, the locking and limiting component includes a slider, a steel ball, and a spring. The slider is connected to the end of the sliding section, and a mounting groove is provided on the slider. The spring is placed in the mounting groove, with one end of the spring connected to the bottom of the mounting groove and the other end connected to the steel ball. The limiting hole is connected to the outside. When the spring is in its natural state, the side of the steel ball away from the mounting groove extends through the limiting hole to the outside.

[0013] Beneficial effects: Once the adjustment position of the sliding section is determined, stop pushing and pulling the sliding section. At this time, the steel ball is aligned with a limiting hole and partially extends out of the limiting hole, thereby locking and limiting the sliding section. The steel ball is highly stable when stuck in the limiting hole, effectively preventing the sliding section from loosening due to the movement of the mouse inside the sleeve. When it is necessary to readjust the position of the sliding section, the operator presses the steel ball inward and then pushes and pulls the sliding section again until the steel ball is stuck in the required limiting hole. This locking method is simple, stable and reliable to operate.

[0014] Furthermore, a limiting groove is provided on the inner wall of the sliding cavity, and the slider is slidably disposed in the limiting groove.

[0015] Beneficial effect: By sliding the slider in the limiting groove, the sliding section can be limited, preventing the sliding section from rotating during pushing and pulling.

[0016] Furthermore, the base is provided with scale lines, which are set parallel to the axis of the sleeve.

[0017] Beneficial effects: Setting scale lines makes it easier to measure the body length of mice and facilitates the recording of mouse body data by experimentalists; on the other hand, the scale lines also make it easier to adjust the length of the sleeve, allowing for more precise adjustment.

[0018] Furthermore, a lighting area is provided at the rear of the base.

[0019] Beneficial effect: Setting up a lighting zone facilitates illumination of the tail end.

[0020] Furthermore, the lighting area is recessed downwards, and a light source and a one-sided condenser are installed in the lighting area. The light source is vertically installed in the recess, and the one-sided condenser is installed on the side wall of the recess.

[0021] Beneficial effects: The use of a light source and a single-sided condenser lens can illuminate the blood vessels in the mouse tail more effectively and clearly, making it easier for operators to observe the location of the blood vessels, improving the accuracy and success rate of tail vein blood collection, and reducing the risk of multiple punctures to mice due to difficulty in locating blood vessels.

[0022] Furthermore, the sidewalls of the recessed portion are inclined outwards.

[0023] Beneficial effect: The outward tilt setting helps the single-sided condenser lens to focus the light source upwards towards the concave part, resulting in a better light focusing effect. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the fixing device in Embodiment 1 of this utility model;

[0025] Figure 2 for Figure 1 A sectional view of the middle sleeve structure;

[0026] Figure 3 for Figure 2 Enlarged view of point A1 in the middle;

[0027] Figure 4 for Figure 1 Schematic diagram of the cross-section of the middle sleeve structure;

[0028] Figure 5 This is a schematic diagram of the structure in Example 2. Detailed Implementation

[0029] The following detailed description illustrates the specific implementation method:

[0030] The markings in the accompanying drawings of the instruction manual include: base 1, support 11, card holder 12, scale line 13, sleeve 2, fixed section 21, sliding cavity 211, limiting hole 212, limiting groove 213, sliding section 22, mesh structure 23, nylon sleeve 231, sealing cap 3, tail hole 31, locking limiting component 4, slider 41, steel ball 42, spring 43, illumination area 5, light source 51, and single-sided condenser lens 52.

[0031] Example 1

[0032] like Figure 1 As shown, a mouse tail vein blood collection and fixation device includes a base 1 and a sleeve 2 disposed on the base 1. The sleeve 2 is used to fix the mouse. In this embodiment, the sleeve 2 is preferably made of transparent material to facilitate observation of the mouse and adjustment of the length of the sleeve 2. The sleeve 2 includes a fixed section 21 and a sliding section 22. The bottom of the fixed section 21 is fixed to the base 1 by a retainer 12. Specifically, the retainer 12 is bolted to the top surface of the base 1. A support seat 11 is also bolted to the base 1. The sliding section 22 is placed on the support seat 11 and is slidably connected to the support seat 11.

[0033] The base 1 is also provided with a scale line 13, which is parallel to the axis of the sleeve 2. The scale line 13 facilitates the measurement of the mouse's body length and makes it convenient for researchers to record the mouse's body data. On the other hand, the scale line 13 is helpful for accurately adjusting the length of the sleeve 2. In this embodiment, the front end of the sliding section 22 is also provided with a conical mesh structure 23, and the smallest end of the mesh structure 23 is provided with a nylon sleeve 231. The rear end of the fixed section 21 is provided with a sealing cap 3, which is tensioned and connected to the fixed section 21. The sealing cap 3 is provided with a tail hole 31.

[0034] like Figure 2 As shown, a sliding cavity 211 is provided in the fixed section 21, one end of the sliding section 22 is slidably disposed in the sliding cavity 211, and a locking limit member 4 is provided at the end of the sliding section 22. A plurality of limiting holes 212 for cooperating with the locking limit member 4 are provided on the wall of the sliding cavity, and the limiting holes 212 are arranged along the axial direction of the fixed section 21.

[0035] like Figure 3As shown, the locking and limiting component 4 includes a slider 41, a steel ball 42, and a spring 43. The slider 41 is connected to the end of the sliding section 22 and extends outward along the radial direction of the sliding section 22. The slider 41 is provided with a mounting groove, and the spring 43 is disposed in the mounting groove. One end of the spring 43 is connected to the bottom of the mounting groove, and the other end is connected to the steel ball 42. In this embodiment, several limiting holes 212 are connected to the outside. When the spring 43 is in its natural state, the side of the steel ball 42 away from the mounting groove extends through the limiting hole 212 to the outside, thereby locking and limiting the sliding section 22. When it is necessary to adjust the sliding section 22, the steel ball 42 is pressed inward and the sliding section 22 is pushed and pulled, so that the steel ball 42 moves into another limiting hole 212.

[0036] Better than Figure 2 , 4 As shown, in this embodiment, a limiting groove 213 is also provided on the inner wall of the sliding cavity 211, and the slider 41 is slidably disposed in the limiting groove 213. Specifically, two sets of limiting grooves 213 are provided, located on the upper and lower sides of the fixed section 21 respectively. A steel ball 42 is provided on the slider 41 located in the upper limiting groove 213 of the fixed section 21, while no steel ball 42 is provided on the slider 41 located in the lower limiting groove 213 of the fixed section 21. The slider 41 mainly serves as a limiting element. In other embodiments besides this one, a steel ball 42 and a spring 43 can also be provided in the slider 41 on the lower side of the fixed section 21, or four sets of limiting grooves 213 and sliders 41 can be provided, with a steel ball 42 and a spring 43 for locking and limiting in one or two of the sets.

[0037] In use, open the sealing cap 3 at the rear end of the fixed section 21, place the mouse into the sleeve 2 from the rear end, and close the sealing cap 3, leaving the mouse's tail protruding from the tail hole 31. Then, press the protruding steel ball 42 inward and push the sliding section 22 to slide within the sliding cavity 211 of the fixed section 21 to adjust the length of the sleeve 2 for better positioning and fixation of the mouse. When the sliding section 22 is adjusted to the appropriate position, the steel ball 42 at the end of the sliding section 22 extends outward under the action of the spring 43 and locks onto the limiting hole 212 of the fixed section 21, thereby locking and limiting the sliding section 22 and ensuring the stability of the sleeve 2. Finally, collect blood from the mouse's tail vein. When it is necessary to collect blood from another mouse, open the sealing cap 3, remove the mouse from the sleeve 2, place another mouse in, and readjust the length of the sleeve 2 again using the above method.

[0038] Example 2

[0039] The difference between this embodiment and Embodiment 1 is that, as Figure 5As shown, the rear end of the base 1 is provided with an illumination area 5; the illumination area 5 is recessed downwards, and a light source 51 and a single-sided condenser lens 52 are provided in the illumination area 5. The light source 51 is vertically arranged in the recess, and the single-sided condenser lens 52 is arranged on the side wall of the recess; more preferably, in this embodiment, the side wall of the recess is inclined outwards, which is conducive to concentrating the light source 51 upwards in the recess.

[0040] This embodiment, by setting up a light source 51 and a single-sided condenser lens 52, can illuminate the tail vein blood vessels of mice more concentratedly and clearly, making it easier for operators to observe the location of the blood vessels, thereby improving the accuracy and success rate of tail vein blood collection and reducing the multiple puncture injuries to mice caused by difficulties in finding blood vessels.

[0041] The above are merely embodiments of this utility model, and the utility model is not limited to the field covered by this embodiment. Commonly known structures and characteristics in the solutions are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the structure of this utility model, and these should also be considered within the scope of protection of this utility model. These modifications will not affect the effectiveness of the implementation of this utility model or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A mouse tail vein blood sampling fixing device comprising a base and a sleeve provided on the base, characterized in that, The sleeve comprises a fixed section and a sliding section, the sliding cavity is arranged in the fixed section, the sliding section is slidingly arranged in the sliding cavity, the end of the sliding section is provided with a locking limiting piece, a plurality of limiting holes for cooperating with the locking limiting piece are arranged on the wall of the sliding cavity, and the limiting holes are arranged along the axial direction of the fixed section; the front end of the sliding section is provided with a conical net structure, the rear end of the fixed section is provided with a sealing cover, and a tail hole is arranged on the sealing cover.

2. The mouse tail vein blood sampling fixation device according to claim 1, characterized in that: The locking limiting piece comprises a sliding block, a steel ball and a spring, the sliding block is connected with the end of the sliding section, the sliding block is provided with a mounting groove, the spring is arranged in the mounting groove, one end of the spring is connected with the bottom of the mounting groove, and the other end is connected with the steel ball; the limiting hole is communicated with the outside, and when the spring is in a natural state, the steel ball passes through the limiting hole and extends to the outside away from the side of the mounting groove.

3. The mouse tail vein blood sampling fixation device according to claim 2, characterized in that: The inner wall of the sliding cavity is further provided with a limiting groove, and the sliding block is slidingly arranged in the limiting groove.

4. The mouse tail vein blood sampling fixation device according to claim 3, characterized in that: The base is provided with a scale line, and the scale line is arranged in parallel with the axis of the sleeve.

5. The mouse tail vein blood sampling fixation device according to any one of claims 1-4, characterized in that: The rear end of the base is provided with an illumination area.

6. The mouse tail vein blood sampling fixation device according to claim 5, wherein: The illumination area is arranged in a downward recess, and a light source and a single-face condenser are arranged in the illumination area, the light source is vertically arranged in the recess, and the single-face condenser is arranged on the side wall of the recess.

7. The mouse tail vein blood sampling fixation device according to claim 6, wherein: The side wall of the recess is arranged in an outward inclination.

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