Biochemical reaction device, sequencing slide and sequencing slide assembly
By designing negative pressure adsorption pores and flow channels on the negative pressure adsorption plate and sequencing slide, the problem of biochemical reaction stage being difficult to adapt to sequencing slides of different sizes was solved, achieving cost reduction and improved thermal conductivity.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-20
- Publication Date
- 2026-03-31
AI Technical Summary
Existing biochemical reaction platforms are difficult to adapt to sequencing slides of different sizes, resulting in complex structures, increased costs, and reduced thermal conductivity.
The design employs a negative pressure adsorption plate and a sequencing slide. The negative pressure adsorption plate has negative pressure adsorption holes, and the sequencing slide has negative pressure flow channels. Vacuum adsorption of the sequencing slide is achieved through the connection between the negative pressure adsorption holes and the flow channels. A temperature control component can be equipped to regulate the temperature.
It achieves universal adaptation to sequencing slides of different sizes, reduces costs, improves thermal conductivity, and simplifies structural design.
Smart Images
Figure CN224062778U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of biochemical reaction equipment, and more specifically, to biochemical reaction apparatus, sequencing slides, and sequencing slide assemblies. Background Technology
[0002] During the sequencing process in a sequencer, sequencing slides typically need to be placed on a biochemical reaction stage for biochemical reactions. Some biochemical reaction stages are equipped with negative pressure suction plates, which can firmly hold and fix the sequencing slides on the surface of the negative pressure suction plates.
[0003] In some existing technologies, the top surface of the negative pressure adsorption plate of the biochemical reaction stage is recessed with negative pressure flow channels to adsorb sequencing slides placed on the negative pressure adsorption plate. However, a single negative pressure adsorption plate is difficult to accommodate various sequencing slides of different sizes. Configuring multiple negative pressure adsorption plates increases the cost of the biochemical reaction stage. Creating multiple adsorption regions on the negative pressure adsorption plate is also a solution to accommodate various sequencing slides, but this leads to a complex negative pressure adsorption plate structure and reduces the contact area between the negative pressure adsorption plate and the sequencing slide, affecting the thermal conductivity between them. Utility Model Content
[0004] This application provides a biochemical reaction apparatus, sequencing slides, and sequencing slide assemblies to address the problem that known biochemical reaction platforms are difficult to adapt to sequencing slides of different sizes.
[0005] In a first aspect, embodiments of this application provide a biochemical reaction apparatus, comprising a negative pressure adsorption plate and a sequencing slide. The negative pressure adsorption plate has at least one negative pressure adsorption hole. The sequencing slide has a support surface and a negative pressure flow channel groove formed recessed from the support surface. When the sequencing slide is stacked on the negative pressure adsorption plate, the support surface is supported by the negative pressure adsorption plate, and at least one negative pressure adsorption hole communicates with the negative pressure flow channel groove.
[0006] In one possible implementation, the number of negative pressure adsorption holes is one; or, the number of negative pressure adsorption holes is multiple, with multiple negative pressure adsorption holes arranged alternately on the negative pressure adsorption plate.
[0007] In one possible implementation, there are multiple sequencing slides. The outer contours of the multiple sequencing slides are different from each other, and / or the shapes of the negative pressure flow channels of the multiple sequencing slides are different from each other. Furthermore, when any one of the multiple sequencing slides is mounted on the negative pressure adsorption plate, at least one negative pressure adsorption hole communicates with the negative pressure flow channel of the sequencing slide.
[0008] In one possible implementation, the biochemical reaction apparatus further includes a temperature control component. The temperature control component is located on the side of the negative pressure adsorption plate opposite to the sequencing slide. The temperature control component is thermally coupled to the negative pressure adsorption plate, which is thermally coupled to the sequencing slide, enabling the temperature control component to control the temperature of the sequencing slide.
[0009] Secondly, embodiments of this application provide a biochemical reaction apparatus, comprising a negative pressure adsorption plate, a transfer plate, and a sequencing slide. The negative pressure adsorption plate has at least one negative pressure adsorption hole. The transfer plate has a negative pressure flow channel hole that extends through the transfer plate along its thickness direction. The sequencing slide has a support surface. Wherein, with the transfer plate stacked on the negative pressure adsorption plate and the sequencing slide stacked on the transfer plate, at least one negative pressure adsorption hole is connected to one end of the negative pressure flow channel hole, and the support surface closes the other end of the negative pressure flow channel hole, forming a negative pressure flow channel groove with the negative pressure flow channel hole.
[0010] In one possible implementation, the support surface is a flat surface.
[0011] In one possible implementation, there are multiple types of sequencing slides and adapter plates. The outer contours of the multiple sequencing slides differ from each other, the outer contours of the multiple adapter plates are adapted to the different sequencing slides, and the shapes of the negative pressure flow channel holes on the multiple adapter plates differ from each other. Furthermore, when any one of the multiple sequencing slides is mounted on the negative pressure adsorption plate via the corresponding adapter plate, at least one negative pressure adsorption hole communicates with the negative pressure flow channel hole of the adapter plate.
[0012] Thirdly, embodiments of this application provide a biochemical reaction apparatus, which includes a negative pressure adsorption plate and a transfer plate. The negative pressure adsorption plate has at least one negative pressure adsorption hole. The transfer plate has a negative pressure flow channel hole that extends through the transfer plate along its thickness direction. When the transfer plate is stacked on top of the negative pressure adsorption plate, at least one negative pressure adsorption hole communicates with the negative pressure flow channel hole.
[0013] Fourthly, embodiments of this application provide a sequencing slide having a support surface. The support surface is concave to form a negative pressure flow channel, used to vacuum-adhere the sequencing slide to the target device.
[0014] Fifthly, embodiments of this application provide a sequencing slide assembly, including a sequencing slide and an adapter plate. The sequencing slide has a support surface. The adapter plate has negative pressure channel holes that extend through the adapter plate along its thickness. When the sequencing slide is stacked on the adapter plate, the support surface and the negative pressure channel holes form a negative pressure channel groove that is open at one end and closed at the other. Attached Figure Description
[0015] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings in the embodiments will be briefly described below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.
[0016] Figure 1 This is a schematic diagram of the structure of a biochemical reaction device according to an embodiment of this application.
[0017] Figure 2 This is a top view of the negative pressure adsorption plate in this embodiment.
[0018] Figure 3 for Figure 1 A schematic diagram of a negative pressure adsorption plate adapted to various sequencing slides.
[0019] Figure 4 for Figure 3 A schematic diagram of the first sequencing slide supported on a negative pressure adsorption plate.
[0020] Figure 5 for Figure 3 A schematic diagram of the second sequencing slide being supported by a negative pressure adsorption plate.
[0021] Figure 6 This is a schematic diagram of another biochemical reaction device according to an embodiment of this application.
[0022] Figure 7 for Figure 6 A schematic diagram of a negative pressure adsorption plate adapted to various sequencing slides.
[0023] Key component symbols: 100, 100a - Biochemical reaction apparatus; 10 - Stage; 11 - Negative pressure adsorption plate; 12 - Vacuum extraction line; 13 - Vacuum pump; 14 - Control valve; 15 - Temperature control component; 20 - Sequencing slide; 20a - First sequencing slide; 20b - Second sequencing slide; 20c - Third sequencing slide; 20d - Fourth sequencing slide; 30 - Adapter plate; 30a - First adapter plate; 30b - Second adapter plate; 110 - Sequencing slide assembly; K1 - Negative pressure adsorption hole; K11 - First negative pressure adsorption hole; K12 - Second negative pressure adsorption hole; K2 - Negative pressure flow channel hole; K21 - First negative pressure flow channel hole; K22 - Second negative pressure flow channel hole; P1 - Top surface; P2 - Support surface; Z - Thickness direction; C1 - Negative pressure flow channel groove; C11 - Inner ring groove; C12 - Outer ring groove; C13 - Cross groove; C14 - Annular groove. Detailed Implementation
[0024] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments.
[0025] It should be noted that when a component is said to be "fixed to" another component, it can be directly on the other component or there may be an intervening component. When a component is said to be "connected to" another component, it can be directly connected to the other component or there may be an intervening component. When a component is said to be "set on" another component, it can be directly set on the other component or there may be an intervening component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.
[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0027] Some embodiments of this application are described in detail. Unless otherwise specified, the following embodiments and features can be combined with each other.
[0028] Example
[0029] See Figure 1 This embodiment provides a biochemical reaction apparatus 100. This biochemical reaction apparatus 100 is used, for example, in the biochemical reaction process of a gene sequencing device.
[0030] The biochemical reaction apparatus 100 includes a stage 10 and a sequencing slide 20.
[0031] The stage 10 includes a negative pressure adsorption plate 11.
[0032] During testing, the sequencing slide 20 can be supported on the negative pressure adsorption plate 11 and fixed and stacked on the negative pressure adsorption plate 11 by vacuum adsorption. After testing, the sequencing slide 20 can be removed from the negative pressure adsorption plate 11.
[0033] In some existing technologies, a negative pressure groove is recessed on the top surface of the negative pressure adsorption plate. When sequencing slides are stacked on the top surface of the negative pressure adsorption plate, the space enclosed by the negative pressure groove and the sequencing slide can be evacuated to adsorb the sequencing slide onto the negative pressure adsorption plate. However, this existing technology is not easily adaptable to various sequencing slides of different sizes. For example, some smaller sequencing slides cannot completely cover the negative pressure groove when supported on the negative pressure adsorption plate, thus making it impossible to adsorb the sequencing slide by evacuation.
[0034] In view of this, this embodiment provides a biochemical reaction device 100, which can realize the vacuum adsorption of sequencing slides 20 of different sizes and has good versatility. It will be described exemplarily below.
[0035] See Figure 1 In the biochemical reaction apparatus 100 of this embodiment, the negative pressure adsorption plate 11 has one or more negative pressure adsorption holes K1. One end of the negative pressure adsorption hole K1 extends to the top surface P1 of the negative pressure adsorption plate 11, and the other end is connected to a vacuum pump 13 through a suction pipe 12. Of course, a control valve 14 or the like can be used on the suction pipe 12 to control the vacuum level.
[0036] The surface of the sequencing slide 20 along its thickness direction Z is a support surface P2, and the sequencing slide 20 has a negative pressure flow channel groove C1 formed by recessing from the support surface P2.
[0037] With the sequencing slide 20 stacked on the top surface P1 of the negative pressure adsorption plate 11, the support surface P2 is in contact with the top surface P1 of the negative pressure adsorption plate 11, and at least one negative pressure adsorption hole K1 is connected to the negative pressure flow channel C1.
[0038] Thus, the vacuum pump 13 can evacuate the negative pressure flow channel C1 through the negative pressure adsorption hole K1, thereby adsorbing and fixing the sequencing slide 20 onto the top surface P1 of the negative pressure adsorption plate 11.
[0039] In this embodiment, optionally, the biochemical reaction apparatus 100 further includes a temperature control component 15. The temperature control component 15 is used to control the temperature of the sequencing slide 20.
[0040] For example, the temperature control component 15 is located on the side of the negative pressure adsorption plate 11 opposite to the sequencing slide 20, and the temperature control component 15 is thermally coupled to the negative pressure adsorption plate 11. When the sequencing slide 20 is stacked on the negative pressure adsorption plate 11, the sequencing slide 20 and the negative pressure adsorption plate 11 are thermally coupled. In this way, the temperature control component 15 can control the temperature of the sequencing slide 20 through the negative pressure adsorption plate 11.
[0041] Since the negative pressure adsorption plate 11 does not require a negative pressure groove, it can provide a larger contact surface, which helps to ensure better heat transfer efficiency between the negative pressure adsorption plate 11 and the sequencing slide 20.
[0042] In other embodiments, the temperature control component 15 may also be located in other locations to control the temperature of the sequencing slide 20 in different ways, which are not limited here.
[0043] Figure 2 This is a top view of the negative pressure adsorption plate 11 in this embodiment.
[0044] See Figure 2 In this embodiment, there are multiple negative pressure adsorption holes K1 (e.g., Figure 2 Two negative pressure adsorption holes K1 (defined as the first negative pressure adsorption hole K11 and the second negative pressure adsorption hole K12, respectively) are arranged alternately on the negative pressure adsorption plate 11. Furthermore, one of the negative pressure adsorption holes K1 (such as the first negative pressure adsorption hole K11) is located at the geometric center of the negative pressure adsorption plate 11, and the other negative pressure adsorption hole K1 (such as the second negative pressure adsorption hole K12) is located to one side of the first negative pressure adsorption hole K11.
[0045] The negative pressure adsorption holes K1 may not be located at the geometric center of the negative pressure adsorption plate 11, but may be located at other locations. No limitation is made here.
[0046] For example, Figure 2 The negative pressure adsorption plate 11 is roughly square. The first negative pressure adsorption hole K11 is located at the intersection of the diagonals of the square, and the second negative pressure adsorption hole K12 is located in the middle of the first negative pressure adsorption hole K11 and one side of the square.
[0047] In other embodiments, the number of negative pressure adsorption holes K1 may be one, three or more, and is not limited here.
[0048] Multiple negative pressure adsorption holes K1 can be controlled by different vacuum pumps 13 or different gas paths.
[0049] See also Figure 3 In this embodiment, there are multiple types of sequencing slides 20. The outer contours of the various sequencing slides 20 are different from each other, and the shapes of the negative pressure flow channel C1 of the various sequencing slides 20 are also different from each other. However, when any one of the various sequencing slides 20 is mounted on the negative pressure adsorption plate 11, at least one negative pressure adsorption hole K1 is connected to the negative pressure flow channel C1 of the sequencing slide 20. In this way, it can be ensured that the negative pressure adsorption plate 11 can accommodate multiple different sequencing slides 20.
[0050] For example, Figure 3 A negative pressure adsorption plate 11 and two sequencing slides 20 are shown. The two sequencing slides 20 include a larger sequencing slide 20 (hereinafter referred to as the first sequencing slide 20a) and a smaller sequencing slide 20 (hereinafter referred to as the second sequencing slide 20b).
[0051] See Figure 3 The negative pressure adsorption plate 11 has only one negative pressure adsorption hole K1.
[0052] The outer contour of the first sequencing slide 20a is roughly square. Its supporting surface P2 has a negative pressure flow channel C1, comprising an inner ring groove C11, an outer ring groove C12, and a cross groove C13. The outer ring groove C12 surrounds the outer periphery of the inner ring groove C11, and the cross groove C13 connects the inner ring groove C11 and the outer ring groove C12. The inner ring groove C11 is circular, and the outer ring groove C12 is square.
[0053] The outer contour of the second sequencing slide 20b is roughly elongated, and the negative pressure flow channel C1 opened on its support surface P2 includes only one annular groove C14.
[0054] See Figure 4 When the first sequencing slide 20a is supported on the negative pressure adsorption plate 11, the negative pressure adsorption hole K1 corresponds to the inner ring groove C11 that is connected to the negative pressure flow channel groove C1.
[0055] See Figure 5 When the second sequencing slide 20b is supported on the negative pressure adsorption plate 11, the negative pressure adsorption hole K1 corresponds to the annular groove C14 that connects to the negative pressure flow channel groove C1. Therefore, the biochemical reaction device 100 of this embodiment can be adapted to different types of sequencing slides 20 through the same negative pressure adsorption plate 11, making it convenient to use.
[0056] Figure 6 Another biochemical reaction apparatus 100a of this embodiment is shown.
[0057] Figure 6 The illustrated biochemical reaction apparatus 100a includes a negative pressure adsorption plate 11, an adapter plate 30, and a sequencing slide 20. The negative pressure adsorption plate 11 has at least one negative pressure adsorption hole K1. The adapter plate 30 has a negative pressure flow channel hole K2, which extends through the adapter plate 30 along its thickness direction Z. The sequencing slide 20 has a support surface P2. When the adapter plate 30 is stacked on the negative pressure adsorption plate 11 and the sequencing slide 20 is stacked on the adapter plate 30, at least one negative pressure adsorption hole K1 is connected to one end of the negative pressure flow channel hole K2, and the support surface P2 closes the other end of the negative pressure flow channel hole K2, forming a negative pressure flow channel groove C1 with the negative pressure flow channel hole K2.
[0058] In use, the vacuum pump 13 can evacuate the negative pressure channel groove C1 through the negative pressure channel hole K2 to achieve vacuum adsorption of the sequencing slide 20. The negative pressure adsorption plate 11 of this biochemical reaction device 100a can also be adapted to different types of sequencing slides 20.
[0059] Figure 6 The biochemical reaction apparatus 100a shown is Figures 3-5The main difference of the biochemical reaction device 100 shown is that the biochemical reaction device 100a is additionally provided with an adapter plate 30 with a negative pressure flow channel hole K2, and the support surface P2 of the sequencing slide 20 does not have a negative pressure flow channel groove C1.
[0060] Since the support surface P2 of the sequencing slide 20 does not require a negative pressure flow channel C1, the processing cost of the sequencing slide 20 is reduced. In this embodiment, there are multiple types of sequencing slides 20. The outer contour shapes of the multiple sequencing slides 20 are different from each other. Correspondingly, there are also multiple types of adapter plates 30. The outer contour shapes of the multiple adapter plates 30 are adapted to the multiple sequencing slides 20, and the shapes of the negative pressure flow channel holes K2 of the multiple adapter plates 30 are different from each other.
[0061] For example, Figure 7 A negative pressure adsorption plate 11, two sequencing slides 20, and two adapter plates 30 are shown. The two sequencing slides 20 include a larger sequencing slide 20 (hereinafter referred to as the third sequencing slide 20c) and a smaller sequencing slide 20 (hereinafter referred to as the fourth sequencing slide 20d).
[0062] Figure 7 In this design, the negative pressure adsorption plate 11 has only one negative pressure adsorption hole K1. Furthermore, the top surface P1 of the negative pressure adsorption plate 11 is not grooved, and only the negative pressure adsorption hole K1 exists.
[0063] The outer contour of the third sequencing slide 20c is roughly square, and its supporting surface P2 is a flat surface. Here, "flat surface" refers to a complete plane without any recessed features such as negative pressure channel grooves C1 or other grooves or holes. The outer contour of the adapter plate 30 (defined as the first adapter plate 30a) corresponding to the third sequencing slide 20c is also roughly square.
[0064] The outer contour of the fourth sequencing slide 20d is roughly elongated, and its supporting surface P2 is a flat surface. The outer contour of the adapter plate 30 (defined as the second adapter plate 30b) corresponding to the fourth sequencing slide 20d is also roughly elongated.
[0065] The negative pressure flow channel holes K2 (defined as the first negative pressure flow channel hole K21) opened in the first adapter plate 30a and K2 (defined as the second negative pressure flow channel hole K22) opened in the second adapter plate 30b are different from each other, so as to adapt to the third sequencing scroll 20c and the fourth sequencing scroll 20d with different shapes respectively. When the third sequencing scroll 20c is supported on the negative pressure adsorption plate 11 by the first adapter plate 30a, the negative pressure adsorption hole K1 is connected to one end of the first negative pressure flow channel hole K21. When the fourth sequencing scroll 20d is supported on the negative pressure adsorption plate 11 by the second adapter plate 30b, the negative pressure adsorption hole K1 is connected to one end of the second negative pressure flow channel hole K22. Thus, the biochemical reaction apparatus 100a of this embodiment can adapt to different kinds of sequencing scrolls 20 through the same negative pressure adsorption plate 11, which is convenient to use.
[0066] Figure 6 and Figure 7 In this assembly, the corresponding sequencing slide 20 and adapter plate 30 together constitute the sequencing slide assembly 110. The adapter plate 30 can be fixedly connected (e.g., glued) to the support surface P2 of the sequencing slide 20, or it can be detachably disposed on the support surface P2 of the sequencing slide 20. In this way, the support surface P2 of the sequencing slide 20 and the negative pressure flow channel hole K2 of the adapter plate 30 form a negative pressure flow channel groove C1 with one end open and the other end closed, so as to facilitate vacuum adsorption through the aforementioned negative pressure adsorption plate 11.
[0067] For example, the third sequencing slide 20c and the first adapter plate 30a can constitute a sequencing slide assembly 110, and the fourth sequencing slide 20d and the second adapter plate 30b can constitute another sequencing slide assembly 110.
[0068] This embodiment also provides a biochemical reaction device, which includes a negative pressure adsorption plate 11 and a transfer plate 30. The negative pressure adsorption plate 11 has at least one negative pressure adsorption hole K1. The transfer plate 30 has a negative pressure flow channel hole K2, which extends through the transfer plate 30 along the thickness direction Z. When the transfer plate 30 is stacked on the negative pressure adsorption plate 11, at least one negative pressure adsorption hole K1 communicates with the negative pressure flow channel hole K2.
[0069] The above embodiments are only used to illustrate the technical solutions of this application and are not intended to limit it. Although this application has been described in detail with reference to the above preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions to the technical solutions of this application should not depart from the spirit and scope of the technical solutions of this application.
Claims
1. A biochemical reaction device, characterized by, The biochemical reaction device comprises: a negative pressure adsorption plate, which is provided with at least one negative pressure adsorption hole; and a sequencing slide, which has a supporting surface and is provided with a negative pressure flow channel groove recessed from the supporting surface; in a state where the sequencing slide is stacked on the negative pressure adsorption plate, the supporting surface is supported on the negative pressure adsorption plate, and at least one negative pressure adsorption hole is communicated with the negative pressure flow channel groove.
2. The biochemical reaction device according to claim 1, wherein: the number of negative pressure adsorption holes is one; or the number of negative pressure adsorption holes is multiple, and multiple negative pressure adsorption holes are arranged at intervals on the negative pressure adsorption plate.
3. The biochemical reaction device according to claim 1, wherein: the sequencing slide has multiple types; the outer contour shapes of multiple types of sequencing slides are different from each other, and / or the shapes of the negative pressure flow channel grooves of multiple types of sequencing slides are different from each other; and when any one of multiple types of sequencing slides is installed on the negative pressure adsorption plate, there is at least one negative pressure adsorption hole communicated with the negative pressure flow channel groove of the sequencing slide.
4. The biochemical reaction device according to claim 1, wherein: the biochemical reaction device further comprises a temperature control assembly; the temperature control assembly is arranged on the side of the negative pressure adsorption plate away from the sequencing slide; the temperature control assembly is thermally coupled with the negative pressure adsorption plate, and the negative pressure adsorption plate can be thermally coupled with the sequencing slide, so that the temperature control assembly can control the temperature of the sequencing slide.
5. A biochemical reaction device characterized by comprising: The biochemical reaction device comprises: a negative pressure adsorption plate, which is provided with at least one negative pressure adsorption hole; an adapter plate, which is provided with a negative pressure flow channel hole penetrating through the adapter plate along the thickness direction of the adapter plate; and a sequencing slide, which has a supporting surface; wherein in a state where the adapter plate is stacked on the negative pressure adsorption plate and the sequencing slide is stacked on the adapter plate, at least one negative pressure adsorption hole is connected with one end of the negative pressure flow channel hole, the supporting surface closes the other end of the negative pressure flow channel hole, and the negative pressure flow channel hole and the supporting surface enclose a negative pressure flow channel groove.
6. The biochemical reaction device according to claim 5, wherein: the supporting surface is a flat surface.
7. The biochemical reaction device according to claim 5, wherein: the sequencing slide and the adapter plate each have multiple types; the outer contour shapes of multiple types of sequencing slides are different from each other, the outer contour shapes of multiple types of adapter plates are respectively adapted to multiple types of sequencing slides, and the shapes of the negative pressure flow channel holes of multiple types of adapter plates are different from each other; and when any one of multiple types of sequencing slides is installed on the negative pressure adsorption plate through a corresponding adapter plate, there is at least one negative pressure adsorption hole communicated with the negative pressure flow channel hole of the adapter plate.
8. A biochemical reaction device, characterized by, The biochemical reaction device comprises: a negative pressure adsorption plate, which is provided with at least one negative pressure adsorption hole; and an adapter plate, which is provided with a negative pressure flow channel hole penetrating through the adapter plate along the thickness direction of the adapter plate. In a state where the adapter plate is laminated to the negative pressure adsorption plate, at least one negative pressure adsorption hole communicates with the negative pressure flow channel hole.
9. A sequencing slide, comprising: the sequencing slide has a support surface; the support surface is concave to form a negative pressure flow channel groove for vacuum adsorbing the sequencing slide to a target object.
10. A sequencing slide assembly, comprising: a sequencing slide having a support surface; an adapter plate having a negative pressure flow channel hole penetrating through the adapter plate along the thickness direction of the adapter plate; in a state where the sequencing slide is laminated to the adapter plate, the support surface and the negative pressure flow channel hole form a negative pressure flow channel groove with one end open and the other end closed.