Gene sequencing chip film forming device
By designing a scaffold and pressing components on a gene sequencing chip and utilizing the channel structure on the drive module and pressing block, the problem of inaccurate positioning in existing film-forming devices was solved, achieving high-precision film-forming effects.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-29
- Publication Date
- 2026-03-31
AI Technical Summary
Existing film-forming devices have low positioning accuracy on gene sequencing chips, making it difficult to accurately introduce solutions into specific locations for film formation.
A film-forming apparatus including a support and a pressing assembly is designed. The support has a groove and the chip has a protrusion. The pressing assembly positions the chip through a drive module and a pressing block. A first channel and a second channel are set on the pressing block to form a complete flow channel. The solution forms a film in the film-forming tank through the channel.
It improves the film-forming positioning accuracy and film-forming effect, simplifies the film-forming process, and achieves a film-forming effect with simple structure and precise positioning.
Smart Images
Figure CN224062897U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of chips, and in particular to a gene sequencing chip film-forming device. Background Technology
[0002] When preparing gene sequencing chips, a film-forming process is required. This process involves introducing a solution into specific locations on the gene sequencing chip to form a film. However, existing film-forming devices suffer from low positioning accuracy, making it difficult to introduce the solution into specific locations on the gene sequencing chip for film formation. Utility Model Content
[0003] In view of this, the present invention provides a gene sequencing chip film forming device to solve the technical problem of low positioning accuracy of existing film forming devices.
[0004] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows:
[0005] A film-forming apparatus, the film-forming apparatus comprising:
[0006] The support has a groove for inserting the chip, the chip has a protrusion, and the protrusion has a film-forming groove. When the chip is placed in the groove, the film-forming groove is located on the side away from the bottom of the groove.
[0007] The assembly includes a pressing component, comprising a drive module and a pressing block. The output end of the drive module is connected to the pressing block. The drive module is used to drive the pressing block closer to or further away from the groove to apply pressure to the chip. The pressing block has a connecting groove into which the protrusion extends. The pressing block has a first channel and a second channel. The inlet of the first channel is located on the pressing block, and the outlet is located at the bottom of the connecting groove. The inlet of the second channel is located at the bottom of the connecting groove, and the outlet is located on the pressing block.
[0008] In some embodiments of the film-forming apparatus, the inlet of the first channel is located on the side wall of the pressing block; and / or, the outlet of the second channel is located on the side wall of the pressing block.
[0009] In some embodiments of the film-forming apparatus, the extension direction of the first channel is parallel to the extension direction of the second channel.
[0010] In some embodiments of the film-forming apparatus, the support includes a frame plate and a plurality of support rods, all of which are fixedly connected to one side of the frame plate. The grooves are located on the side of the frame plate away from the support rods, and there are a plurality of grooves arranged in a circumferential array.
[0011] The number of the pressing components is multiple, and each pressing component is configured to correspond one-to-one with each of the grooves.
[0012] In some embodiments of the film-forming apparatus, a through hole is provided through the frame plate, and each of the grooves is arranged in the through hole;
[0013] Each of the pressing components includes a drive module located in the extension path of the inner wall of the through hole. Each pressing component also includes a transmission component, each transmission component including a first segment and a second segment connected to each other. The side of the first segment away from the second segment is connected to the output end of the drive module. The second segment is set at an angle to the first segment. One side of each second segment is opposite to each groove. The pressing block is fixedly connected to the side of the second segment opposite to the groove.
[0014] In some embodiments of the film-forming apparatus, the included angle between the first segment and the second segment is 90°.
[0015] In some embodiments of the film-forming apparatus, the drive module includes a drive component and a ball screw. The output end of the drive component is fixedly connected to the ball screw and is used to drive the ball screw to rotate forward and backward. The nut of the ball screw is fixedly connected to the transmission component so as to drive the transmission component to move closer to or away from the frame plate.
[0016] In some embodiments of the film-forming apparatus, the support further includes a base plate, and the ends of each of the support rods facing away from the support plate are fixedly connected to the base plate.
[0017] In some embodiments of the film-forming apparatus, the drive module further includes a fixed plate and a bearing seat. The fixed plate is fixedly connected to the base plate and extends along the extension direction of the ball screw. The bearing seat is fixedly connected to the fixed plate and sleeved on the end of the ball screw away from the drive member.
[0018] The driving component is fixedly connected to the fixed plate; the transmission component is slidably connected to the fixed plate.
[0019] In some embodiments of the film-forming apparatus, the drive module further includes a guide rail and a slider. The guide rail is fixedly connected to the fixed plate, and the extension direction of the guide rail is parallel to the extension direction of the ball screw. The slider is slidably connected to the guide rail, and the side of the slider away from the guide rail is fixedly connected to the transmission component.
[0020] Implementing the embodiments of this utility model will have at least the following beneficial effects:
[0021] The aforementioned chip film-forming apparatus has the technical advantages of improving film-forming positioning accuracy and achieving good film-forming effect. Specifically, the film-forming apparatus of this invention, through the action of the driving module, can drive the pressure block to move and abut against the chip placed in the groove. The pressure block has a connecting groove that allows the protrusion to extend into it. This combination improves positioning accuracy. The film-forming position of the chip is the film-forming groove on the protrusion, which is connected to the connecting groove. The pressure block also has a first channel and a second channel. The first channel and the second channel, together with the connecting groove, form a complete flow channel that can be used to allow the solution to pass through. Thus, a film is formed in the film-forming groove. By setting the channel on the pressure block, the film-forming method is simplified, making the film-forming apparatus of this invention have the beneficial effects of simple structure, high film-forming positioning accuracy, and good film-forming effect. Attached Figure Description
[0022] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0023] Figure 1 This is a schematic diagram of the overall structure of the film-forming device in one embodiment;
[0024] Figure 2 for Figure 1 A schematic diagram of the structure of the drive module;
[0025] Figure 3 This is a schematic diagram of the pressure block in one embodiment;
[0026] Figure 4 for Figure 3 The rear view of the pressure block shown;
[0027] Figure 5 for Figure 1 A schematic diagram of the chip structure.
[0028] in:
[0029] 1. Bracket; 11. Shelf plate; 111. Groove; 112. Through hole; 12. Support rod; 13. Base plate;
[0030] 2. Pressing assembly; 21. Drive module; 211. Drive component; 212. Ball screw; 213. Fixing plate; 214. Bearing seat; 215. Guide rail; 216. Slider; 22. Pressure block; 221. First channel; 222. Second channel; 223. Connecting groove; 23. Transmission component; 231. First section; 232. Second section;
[0031] 100. Chip; 101. Bump; 102. Film-forming groove. Detailed Implementation
[0032] To facilitate understanding of this utility model, a more complete description will be given below with reference to the accompanying drawings. The drawings illustrate preferred embodiments of this utility model. However, this utility model can be implemented in many other different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to provide a more thorough and complete understanding of the disclosure of this utility model.
[0033] It should be noted that when a component is said to be "fixed to" another component, it can be directly attached to the other component or there may be an intervening component. When a component is said to be "connected to" another component, it can be directly connected to the other component or there may be an intervening component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.
[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.
[0035] It should be emphasized and explained here that the various connection methods involved in this invention can be arbitrary unless otherwise specified. For example, fixed connection can be achieved by bolts and nuts for detachable fixing, welding or integral molding, etc. Sliding connection can be achieved by groove-like or guide rail-like structures of various shapes, and rotating connection can be achieved by hinges, shafts, etc. Any existing method that can achieve the corresponding connection relationship is acceptable.
[0036] The following is combined Figure 1-5 The following provides a further explanation of the gene sequencing chip film-forming device involved in this utility model.
[0037] In one embodiment of a gene sequencing chip 100 film-forming device, the film-forming device includes a support 1 and a pressing assembly 2. The support 1 has a groove 111 for the chip 100 to be placed in, and the chip 100 has a protrusion 101. A film-forming groove 102 is formed on the protrusion 101. When the chip 100 is placed in the groove 111, the film-forming groove 102 is located on the side opposite to the bottom of the groove 111. The pressing assembly 2 includes a driving module 21 and a pressing block 22. The output end of the driving module 21 is connected to the pressing block 22. The driving module 21 is used to drive the pressing block 22 to move closer to or away from the groove 111 so as to apply pressure to the chip 100. The pressing block 22 is provided with a connecting groove 223 into which the protrusion 101 extends. The pressing block 22 is provided with a first channel 221 and a second channel 222. The entrance of the first channel 221 is opened on the pressing block 22, and the exit is opened at the bottom of the connecting groove 223. The entrance of the second channel 222 is opened at the bottom of the connecting groove 223, and the exit is opened on the pressing block 22.
[0038] In this embodiment, the driving module 21 drives the pressure block 22 to move and abut against the chip 100 placed in the groove 111. The pressure block 22 has a connecting groove 223, which allows the protrusion 101 to extend into. This combination improves the positioning accuracy. The film-forming position of the chip 100 is the film-forming groove 102 on the protrusion 101, which is connected to the connecting groove 223. The pressure block 22 also has a first channel 221 and a second channel 222. The first channel 221 and the second channel 222, together with the connecting groove 223, form a complete flow channel, which can be used to allow the solution to pass through. Thus, a film is formed in the film-forming groove 102. By setting the channel on the pressure block 22, the film-forming method is simplified, and the film-forming device of this utility model has the beneficial effects of simple structure, high film-forming positioning accuracy and good film-forming effect.
[0039] Specifically, the drive module 21 can be a variety of linear drive mechanisms, such as a cylinder, hydraulic cylinder, linear motor, etc. The connection between the drive module 21 and the pressure block 22 can be direct or indirect, as long as it can drive the pressure block 22 to reciprocate linearly.
[0040] In addition, it is understood that in this embodiment, the flow channel of the solution is set on the pressure block 22, which can be set at any position on the pressure block 22, such as the upper wall or the side wall. The opening on the corresponding connecting groove 223 is opened at the bottom of the groove. Since the bottom of the connecting groove 223 can be opposite to the film forming groove 102, it is convenient for the solution to enter the film forming groove 102. On the one hand, the pressure block 22 itself has the effect of cooperating and positioning with the chip 100 by setting the connecting groove 223. Then, the flow channel of the solution is combined with the pressure block 22. After the pressure block 22 is pressed on the chip 100, the solution is passed through to form a film. The structure is simple and the precision is higher.
[0041] In one embodiment of a film-forming apparatus, the inlet of the first channel 221 is opened on the side wall of the pressing block 22, and / or the outlet of the second channel 222 is opened on the side wall of the pressing block 22.
[0042] In this embodiment, by setting the inlet of the first channel 221 on the side wall of the pressure block 22, it is convenient to connect external pipelines. Similarly, the outlet of the second channel 222 is opened on the side wall of the pressure block 22, which is also convenient to connect external pipelines. Furthermore, since it needs to be connected to the opening at the bottom of the connecting groove, setting the inlet of the first channel 221 and the outlet of the second channel 222 on the side wall of the pressure block 22 can also reduce the number of bends in the channels.
[0043] In one embodiment of the film-forming apparatus, the extension direction of the first channel 221 is parallel to the extension direction of the second channel 222.
[0044] In this embodiment, the first channel 221 and the second channel 222 can be arranged at intervals. By setting the extension directions of the first channel 221 and the second channel 222 to be parallel, the flow direction can be unified, which is convenient for opening and can be used in both directions, reducing the difficulty of assembly.
[0045] In one embodiment of a film-forming apparatus, the support 1 includes a frame plate 11 and a plurality of support rods 12. Each support rod 12 is fixedly connected to one side of the frame plate 11. A groove 111 is located on the side of the frame plate 11 opposite to the support rods 12. There are multiple grooves 111 arranged in a circumferential array. There are also multiple pressing components 2, each corresponding to one of the grooves 111.
[0046] In this embodiment, by setting multiple grooves 111, multiple chips 100 can be placed, improving production efficiency. Correspondingly, multiple pressing components 2 are also set, which can drive one-to-one to avoid affecting positioning accuracy.
[0047] In one embodiment of a film-forming apparatus, a through hole 112 is provided on the frame plate 11, and each of the grooves 111 is arranged around the through hole 112. Each of the driving modules 21 in each of the pressing components 2 is located in the extension path of the inner wall of the through hole 112. Each of the pressing components 2 also includes a transmission member 23, each of the transmission members 23 including a first segment 231 and a second segment 232 connected to each other. The side of the first segment 231 away from the second segment 232 is connected to the output end of the driving module 21. The second segment 232 is set at an angle to the first segment 231. One side of each second segment 232 is opposite to each of the grooves 111. The pressing block 22 is fixedly connected to the side of the second segment 232 opposite to the groove 111.
[0048] In this embodiment, by forming through holes 112 in the mounting plate 11, a "mouth" shape can be formed, and the driving modules 21 are all arranged in the extending path of the inner wall of the through holes 112, which can improve the stability of the overall device. In addition, it can be understood that the grooves 111 are provided on the mounting plate 11, while the driving modules 21 are in the extending path of the inner wall of the through holes 112. Thus, in the axial direction of the through holes 112, the positions between the driving modules 21 and the grooves 111 are not directly opposite, resulting in a positional deviation. This embodiment solves this problem by providing a transmission member 23. The transmission member 23 has a first section 231 and a second section 232 arranged at an angle, that is, it extends towards the position of the groove 111.
[0049] It can be understood that the extending path of the inner wall of the through hole 112 is understood as forming an axially extending tubular region, and the driving module 21 is arranged within this region, corresponding to being inside.
[0050] Preferably, the angle between the first section 231 and the second section 232 is 90°. When the angle between the first section 231 and the second section 232 is 90°, they form a T-shaped or L-shaped structural member, which is flattened, facilitating installation and reducing the positioning difficulty due to non-uniformity.
[0051] In an embodiment of a film forming device, the driving module 21 includes a driving member 211 and a ball screw 212. The output end of the driving member 211 is fixedly connected to the ball screw 212 and is used to drive the ball screw 212 to rotate forward and backward. The nut of the ball screw 212 is fixedly connected to the transmission member 23 to be able to drive the transmission member 23 to approach or move away from the mounting plate 11.
[0052] In this embodiment, the use of a ball screw 212 can improve the precision and is convenient for control. It can be understood that the ball screw 212 can be connected to the driving member 211 through a coupling.
[0053] Specifically, a precision ball screw 212 can be selected, and the driving member 211 can be a servo motor, which can further improve the precision.
[0054] The positioning precision of the ball screw 212-driven transmission system can reach 0.02 mm, and the repeat positioning precision is 0.01 mm. The position compensation of the screw is performed through the operating system. The specific method is as follows: within the stroke range, the nut moves from the 0 position of the stroke to the 20 position. Then, it continues to move from the 20 position to the 40 position. Then, it continues to move from the 40 position to the 60 position. Until it runs to the 100 position of the stroke, a high-precision laser interferometer is used as a tool to read the actual value of the numerical value. After comparison, compensation is performed, and the summary data is shown in Table 1 below:
[0055] scope ≦20 ≦40 ≦60 ≦80 ≦100 Input value 8.02 30.00 55.19 72.99 97.34 actual value 8.011 29.981 55.174 72.982 97.326 Compensation value 0.009 0.019 0.016 0.010 0.014
[0056] The overall compensation value of ball screw 212 is 0.0136.
[0057] After system compensation, the positioning accuracy of the lead screw is calculated to be 0.005mm and the repeatability is 0.003mm. Compared with the positioning accuracy of 0.02mm and the repeatability of 0.01mm before compensation, the accuracy is greatly improved. This method fully meets the high precision requirements of the equipment.
[0058] In one embodiment of the film-forming apparatus, the support 1 further includes a base plate 13, and the ends of each of the support rods 12 that are away from the frame plate 11 are fixedly connected to the base plate 13.
[0059] In this embodiment, by setting a base plate 13, the base plate 13, the support rod 12 and the frame plate 11 form a whole, which further improves stability.
[0060] In one embodiment of the film-forming apparatus, the drive module 21 further includes a fixed plate 213 and a bearing seat 214. The fixed plate 213 is fixedly connected to the base plate 13 and extends along the extension direction of the ball screw 212. The bearing seat 214 is fixedly connected to the fixed plate 213 and is sleeved on the end of the ball screw 212 away from the drive member 211. The drive member 211 is fixedly connected to the fixed plate 213. The transmission member 23 is slidably connected to the fixed plate 213.
[0061] In this embodiment, a fixed plate 213 and a bearing seat 214 are added. The bearing seat 214 and the drive component 211 are respectively connected to the two ends of the ball screw 212 to form the existing ball screw 212 module, which is more stable. The fixed plate 213 can facilitate the installation of the bearing seat 214 and the drive component 211 to form a whole. On the other hand, the transmission component 23 is slidably connected to the fixed plate 213, which can play a guiding role and further improve the motion accuracy.
[0062] Specifically, in one embodiment, the drive module 21 further includes a guide rail 215 and a slider 216. The guide rail 215 is fixedly connected to the fixed plate 213, and the extension direction of the guide rail 215 is parallel to the extension direction of the ball screw 212. The slider 216 is slidably connected to the guide rail 215, and the side of the slider 216 facing away from the guide rail 215 is fixedly connected to the transmission member 23.
[0063] In this embodiment, the sliding mechanism between the transmission component 23 and the fixed plate 213 is achieved by the guide rail 215 and the slider 216. The guide rail 215 has a higher guiding accuracy than the guide groove.
[0064] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0065] The above embodiments only illustrate several implementation methods of this utility model, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these all fall within the protection scope of this utility model. Therefore, the protection scope of this utility model patent should be determined by the appended claims.
Claims
1. A gene sequencing chip film forming apparatus, characterized by comprising: The film forming device comprises: A support provided with a recess capable of accommodating the chip, the chip being provided with a protrusion, the protrusion being provided with a film forming groove, the film forming groove being located on a side away from the recess bottom when the chip is accommodated in the recess; And a pressing assembly comprising a driving module and a pressing block, the output end of the driving module being connected to the pressing block, the driving module being used to drive the pressing block to approach or move away from the recess so as to be capable of pressing the chip, the pressing block being provided with a communication groove for the protrusion to extend into, the pressing block being provided with a first channel and a second channel, the inlet of the first channel being formed on the pressing block, and the outlet being formed on the bottom of the communication groove, the inlet of the second channel being formed on the bottom of the communication groove, and the outlet being formed on the pressing block.
2. The film forming apparatus according to claim 1, wherein The inlet of the first channel is formed on the side wall of the pressing block; and / or, the outlet of the second channel is formed on the side wall of the pressing block.
3. The film forming apparatus according to claim 1, wherein The extension direction of the first channel is parallel to the extension direction of the second channel.
4. The film forming apparatus according to claim 1, wherein The support comprises a shelf plate and a plurality of support rods, the plurality of support rods being fixedly connected to one side of the shelf plate, the recess being arranged on a side of the shelf plate away from the support rods, the number of the recesses being a plurality, and each of the recesses being arranged in a circumferential array; The number of the pressing assemblies is a plurality, and each of the pressing assemblies is arranged in one-to-one correspondence with each of the recesses.
5. The film forming apparatus according to claim 4, wherein The shelf plate is provided with a through hole penetrating through the shelf plate, and each of the recesses is arranged around the through hole; Each of the driving modules in each of the pressing assemblies is located in the extension path of the inner wall of the through hole, each of the pressing assemblies further comprises a transmission member, each of the transmission members comprises a first segment and a second segment connected to each other, the output end of the driving module is connected to the side of the first segment away from the second segment, the second segment is arranged at an angle with the first segment, one side of each of the second segments is opposite to each of the recesses, and the pressing block is fixedly connected to the side of the second segment opposite to the recess.
6. The film forming apparatus according to claim 5, wherein The angle between the first segment and the second segment is 90°.
7. The film forming apparatus according to claim 5, wherein The driving module comprises a driving member and a ball screw, the output end of the driving member is fixedly connected to the ball screw, and the driving member is used to drive the ball screw to rotate in opposite directions, the nut of the ball screw is fixedly connected to the transmission member so as to be capable of driving the transmission member to approach or move away from the shelf plate.
8. The film forming apparatus according to claim 7, wherein The support further comprises a bottom plate, and the end of each of the support rods away from the shelf plate is fixedly connected to the bottom plate.
9. The film forming apparatus according to claim 8, wherein The driving module further comprises a fixed plate and a bearing seat, the fixed plate is fixedly connected to the bottom plate and extends along the extension direction of the ball screw, and the bearing seat is fixedly connected to the fixed plate and is sleeved on the end of the ball screw away from the driving member; The driving member is fixedly connected to the fixed plate, and the transmission member is slidingly connected to the fixed plate.
10. The film forming apparatus according to claim 9, wherein The driving module further comprises a guide rail and a sliding block, the guide rail is fixedly connected to the fixed plate, the extension direction of the guide rail is parallel to the extension direction of the ball screw, the sliding block is slidingly connected to the guide rail, and the side of the sliding block away from the guide rail is fixedly connected to the transmission member.