Cell separation, flaking and dyeing all-in-one machine

Abstract

The utility model provides a cell separating, flaking and dyeing all-in-one machine. The cell separation, sheet preparation and dyeing all-in-one machine comprises a shell; the cleaning device comprises a shell and two mounting ports, the two mounting ports are formed in the positions, located at the bottom, of the back face of the shell, a cleaning fluid frame is mounted in one mounting port, a row of first butt-joint ports are formed in the top of the cleaning fluid frame, a protective shell is mounted on the back face of the cleaning fluid frame, and a miniature conveying pump is mounted in the protective shell. A conveying pipe is mounted at an outlet of the micro conveying pump, a suction pipe is mounted at an inlet of the micro conveying pump, and a waste liquid frame is mounted in the other mounting opening; the test tube table is mounted at the position, close to one side, of the bottom of the inner wall of the shell. According to the cell separation, flaking and dyeing all-in-one machine provided by the utility model, the dyeing needle can be automatically cleaned after being used through the design, so that the dyeing needle does not need to be frequently replaced, and the operation efficiency of the cell separation, flaking and dyeing all-in-one machine is favorably improved.

Description

Technical Field

[0001] This utility model relates to the technical field of integrated cell separation, slide preparation and staining machine, and in particular to an integrated cell separation, slide preparation and staining machine. Background Technology

[0002] There is no universally accepted definition of a cell. A more common definition is that a cell is the basic structural and functional unit of an organism. It is known that all organisms except viruses are composed of cells, but viral life activities can only be manifested in cells.

[0003] The cell separation, slide preparation, and staining integrated machine utilizes medical natural sedimentation liquid-based cytology reagent technology and mechanical principles to separate cells from the suspension and uniformly deposit them onto a glass slide. Due to the unique encapsulation technology of the reagent, a single layer of cells can be formed on the glass slide, resulting in an ultrathin cell smear with abundant cells, a clear background, intact morphology, and uniform distribution.

[0004] The staining needles in existing cell separation, slide preparation, and staining machines are detachable. To avoid contamination between staining solutions, the staining needles need to be replaced after each operation, which is cumbersome and affects the operating efficiency of the cell separation, slide preparation, and staining machine.

[0005] Therefore, it is necessary to provide a cell separation, slide preparation, and staining integrated machine to solve the above-mentioned technical problems. Utility Model Content

[0006] This invention provides a cell separation, slide preparation, and staining integrated machine, which solves the problem that the cumbersome operation of disassembling and replacing staining needles after each use affects the operating efficiency of the integrated machine.

[0007] To solve the above-mentioned technical problems, the cell separation, slide preparation and staining integrated machine provided by this utility model includes: a housing;

[0008] Two mounting ports are located on the back of the housing at the bottom. One of the mounting ports is equipped with a cleaning fluid frame. The top of the cleaning fluid frame has a first pair of interfaces. A protective shell is installed on the back of the cleaning fluid frame. A miniature delivery pump is installed inside the protective shell. A delivery pipe is installed at the outlet of the miniature delivery pump. A suction pipe is installed at the inlet of the miniature delivery pump. A waste liquid frame is installed in the other mounting port.

[0009] The test tube station is installed on the bottom of the inner wall of the shell near one side, and a slide preparation station is installed on the bottom of the inner wall of the shell near the other side. A Cartesian coordinate robot is installed inside the inner wall of the shell, and a staining needle is installed on the bottom of the Cartesian coordinate robot through an auxiliary docking device.

[0010] The other end of the delivery pipe is connected to the cleaning fluid frame to deliver the cleaning fluid into the cleaning fluid frame. The auxiliary docking device can help the dyeing needle to be accurately positioned and aligned. The top of the shell has an opening that can be covered by a transparent cover as needed.

[0011] Preferably, a baffle is installed at the bottom of the inner wall of the housing, located on the front side. An operation screen is installed on the front of the baffle via a mounting base, and a connecting pipe is installed at the other end of the straw via a filter tube.

[0012] The control panel allows you to set the operating parameters of the equipment inside the housing. The front of the housing can be covered by a transparent panel, and a filter screen is installed inside the filter tube.

[0013] Preferably, an air inlet is provided on one side of the housing, and a heat dissipation structure with a protective plate is installed on the other side of the housing;

[0014] The protective plate has holes.

[0015] Preferably, a discharge pipe is installed on the back of the waste liquid frame, and a valve is installed at the other end of the discharge pipe;

[0016] Opening the valve allows the liquid inside the waste container to be discharged.

[0017] Preferably, a fixed base is installed on both sides of the inner wall of the housing near the back, and a disinfection lamp is installed between each fixed base.

[0018] Preferably, an adjustment base is installed at the bottom of the housing. The adjustment base includes a base plate, and internal threaded bolts are fixedly connected to the four corners of the bottom of the base plate. The bottom of the internal threaded bolts is threadedly connected to a contact plate via an adjustment screw.

[0019] The adjusting screw can be adjusted to the desired height, allowing the housing to work more stably.

[0020] Compared with related technologies, the cell separation, slide preparation, and staining integrated machine provided by this utility model has the following advantages:

[0021] Beneficial effects:

[0022] This invention provides an integrated cell separation, slide preparation, and staining machine. To facilitate needle cleaning and improve the machine's operating efficiency, two mounting ports are provided on the back of the housing. A cleaning solution container and a waste solution container are then installed in these ports. The tops of the cleaning solution container and the waste solution container each have a first pair of interfaces and a second pair of interfaces, facilitating needle insertion. The disinfectant in the cleaning solution container is supplied by a micro-pump, and a micro-level sensor inside the container monitors the liquid level. This design allows for automatic needle cleaning after use, eliminating the need for frequent needle replacements and improving the overall operating efficiency of the integrated cell separation, slide preparation, and staining machine. Attached Figure Description

[0023] Figure 1 A schematic diagram of a preferred embodiment of the cell separation, slide preparation, and staining integrated machine provided by this utility model;

[0024] Figure 2 A schematic diagram of the cleaning fluid frame is provided for this utility model;

[0025] Figure 3 A structural schematic diagram of the mounting port is provided for this utility model;

[0026] Figure 4 A schematic diagram of the structure of the miniature delivery pump is provided for this utility model;

[0027] Figure 5 Provided for this utility model Figure 1 An enlarged view of point A shown.

[0028] The diagram is labeled as follows: 1. Shell, 2. Cartesian robot, 3. Sterilization lamp, 4. Fixed base, 5. Film preparation table, 6. Baffle, 7. Operation panel, 8. Mounting base, 9. Adjustment base, 901. Base plate, 902. Internal threaded bolt, 903. Adjusting screw, 904. Contact plate, 10. Test tube stand, 11. Air inlet, 12. Heat dissipation structure, 13. Delivery pipe, 14. Protective shell, 15. Pipe, 16. Cleaning liquid frame, 17. Waste liquid frame, 18. Valve, 19. Discharge pipe, 20. First pair of interfaces, 21. Connecting pipe, 22. Filter pipe, 23. Second pair of interfaces, 24. Mounting port, 25. Miniature delivery pump, 26. Auxiliary docking equipment, 27. Staining needle, 28. Protective plate. Detailed Implementation

[0029] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0030] Please refer to the following: Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5,in, Figure 1 A schematic diagram of a preferred embodiment of the cell separation, slide preparation, and staining integrated machine provided by this utility model; Figure 2 A schematic diagram of the cleaning fluid frame is provided for this utility model; Figure 3 A structural schematic diagram of the mounting port is provided for this utility model;

[0031] Figure 4 A schematic diagram of the structure of the miniature delivery pump is provided for this utility model; Figure 5 Provided for this utility model Figure 1 The enlarged view at point A is shown. The cell separation, slide preparation, and staining integrated machine includes: a housing 1;

[0032] Two mounting ports 24 are located on the back of the housing 1 at the bottom. A cleaning fluid frame 16 is installed in one of the mounting ports 24. A first pair of interfaces 20 are provided on the top of the cleaning fluid frame 16. A protective shell 14 is installed on the back of the cleaning fluid frame 16. A micro-pump 25 is installed inside the protective shell 14. A delivery pipe 13 is installed at the outlet of the micro-pump 25. A suction pipe 15 is installed at the inlet of the micro-pump 25. A waste liquid frame 17 is installed in the other mounting port 24.

[0033] Test tube station 10, the test tube station 10 is installed at the bottom of the inner wall of the housing 1 near one side, the bottom of the inner wall of the housing 1 near the other side is installed with a slide preparation table 5, the inner wall of the housing 1 is installed with a rectangular coordinate robot 2 inside, and the bottom of the rectangular coordinate robot 2 is installed with a staining needle 27 through an auxiliary docking device 26.

[0034] The other end of the delivery pipe 13 is connected to the cleaning fluid frame 16 to deliver the cleaning fluid into the cleaning fluid frame 16. The auxiliary docking device 26 can assist the dyeing needle 27 in precise positioning and alignment. The top of the housing 1 has an opening, which can be covered by a transparent cover as needed, as long as it does not affect the operation of the Cartesian coordinate robot 2.

[0035] A baffle 6 is installed at the bottom of the inner wall of the housing 1 on the front side. An operation screen 7 is installed on the front of the baffle 6 via a mounting base 8. The other end of the straw 15 is connected to a connecting pipe 21 via a filter pipe 22.

[0036] The operation panel 7 can set the operating parameters of the equipment inside the housing 1. The front of the housing 1 can be covered by a transparent plate. The filter tube 22 is equipped with a filter screen. The connecting tube 21 is connected to the cleaning fluid tank.

[0037] An air inlet 11 is provided on one side of the housing 1, and a heat dissipation structure 12 with a protective plate 28 is installed on the other side of the housing 1.

[0038] The protective plate 28 has holes, and the heat dissipation structure 12 includes a mounting frame and a cooling fan.

[0039] A discharge pipe 19 is installed on the back of the waste liquid frame 17, and a valve 18 is installed at the other end of the discharge pipe 19.

[0040] Opening valve 18 allows the liquid inside waste liquid box 17 to be discharged.

[0041] A fixed base 4 is installed on both sides of the inner wall of the housing 1 near the back, and a disinfection lamp 3 is installed between each fixed base 4.

[0042] The disinfection lamp 3 can disinfect the inside of the housing 1 as needed.

[0043] An adjusting base 9 is installed at the bottom of the housing 1. The adjusting base 9 includes a base plate 901. Internal threaded bolts 902 are fixedly connected to the four corners of the bottom of the base plate 901. The bottom of the internal threaded bolts 902 is threadedly connected to a contact plate 904 through an adjusting screw 903.

[0044] The adjusting screw 903 can be adjusted in height as needed, allowing the housing 1 to work more stably. The bottom of the contact plate 904 is equipped with an anti-slip pad.

[0045] The working principle of the cell separation, slide preparation, and staining integrated machine provided by this utility model is as follows:

[0046] Two mounting ports 24 are provided on the back of the housing 1. The cleaning solution container 16 and the waste solution container 17 are then installed in these ports 24. The tops of the cleaning solution container 16 and the waste solution container 17 are respectively provided with a first pair of interfaces 20 and a second pair of interfaces 23, facilitating the insertion of the staining needle 27. The disinfectant in the cleaning solution container 16 is delivered by a micro-pump 25, and a micro-level sensor inside the cleaning solution container 16 monitors the liquid level. In actual use, the test tube containing the cell staining solution is first placed on the test tube stand 10. Then, the Cartesian coordinate robot 2 is activated, moving the staining needle 27 above the test tube and downwards. The staining needle 27, containing the cell staining solution, is inserted into the test tube and aspirated. Then, the Cartesian robot 2 moves the staining needle 27 to the slide preparation table 5 to drain the liquid into the corresponding position for slide preparation. During this process, the Cartesian robot 2 moves the staining needle 27 above the cleaning solution box 16, allowing the staining needle 27 to be inserted through the first pair of interfaces 20. The cleaning solution is then washed out from inside the cleaning solution box 16. Afterward, the staining needle 27 is moved to the waste liquid box 17 and inserted through the second pair of interfaces 23 to drain the cleaned liquid. This process can be repeated as needed to clean the staining needle 27. Afterward, the corresponding cell staining solution can be extracted from the test tube.

[0047] Compared with related technologies, the cell separation, slide preparation, and staining integrated machine provided by this utility model has the following advantages:

[0048] Beneficial effects:

[0049] To facilitate cleaning of staining needles and improve the operating efficiency of the cell separation, slide preparation, and staining integrated machine, two mounting ports 24 are provided on the back of the housing 1. The cleaning solution frame 16 and waste solution frame 17 are then installed in these ports 24. The tops of the cleaning solution frame 16 and waste solution frame 17 are respectively provided with a first pair of interfaces 20 and a second pair of interfaces 23, facilitating the insertion of the staining needle 27. The disinfectant in the cleaning solution frame 16 is delivered by a micro-pump 25, and a micro-level sensor inside the cleaning solution frame 16 monitors the liquid level. This design allows for automatic cleaning of the staining needle 27 after use, eliminating the need for frequent needle replacements and improving the operating efficiency of the cell separation, slide preparation, and staining integrated machine.

[0050] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the content of this utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.

Claims

1. A cell separation, preparation, staining and dyeing integrated machine, characterized in that, Include: The shell; Two installation port, two said installation port opening in the back of the shell located at the bottom of the position, one of the installation port in the installation of cleaning fluid frame, the top of the cleaning fluid frame is equipped with a row of first interface, the back of the cleaning fluid frame is equipped with a protective shell, the inside of the protective shell is equipped with a micro pump, the outlet of the micro pump is equipped with a delivery pipe, the inlet of the micro pump is equipped with a suction tube, the other said installation port is equipped with a waste liquid frame; Test tube table, said test tube table is installed in the bottom of the shell wall near one side of the position, the bottom of the shell wall near the other side of the position is equipped with a slide table, the inside of the shell wall is equipped with a cartesian robot, the bottom of the cartesian robot is equipped with a dyeing needle through auxiliary docking equipment.

2. The cell separation, preparation, staining and dyeing integrated machine according to claim 1, characterized in that, The bottom of the shell wall is equipped with a baffle in the front of the position, the front of the baffle is equipped with an operation screen through the installation of the base, the other end of the suction tube is equipped with a docking pipe through the filter pipe.

3. The cell separation, preparation, staining and dyeing integrated machine according to claim 1, characterized in that, The shell is equipped with an air inlet hole on one side, and the other side of the shell is equipped with a heat dissipation structure with a protective plate.

4. The cell separation, preparation, staining and integration machine according to claim 1, wherein, The back of the waste liquid frame is equipped with a discharge pipe, and the other end of the discharge pipe is equipped with a valve.

5. The cell separation, preparation, staining and integration machine according to claim 1, wherein, The bottom of the shell wall is equipped with a fixed base near the back of the position, and a disinfection lamp is installed between each fixed base.

6. The cell separation, preparation, staining and integration machine according to claim 1, wherein, The bottom of the shell is equipped with an adjusting base, which includes a bottom plate, and the bottom of the bottom plate is fixedly connected with an internal thread bolt at four corners.

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