Toxicology cell incubator

Abstract

The utility model relates to the technical field of biomedicine, and discloses a toxicological cell incubator which comprises a working panel and supporting legs fixedly mounted on two sides of the lower end of the working panel, firstly, a movable door is taken down, and culture cells are placed on a culture bracket; after placement is completed, the movable door can be inserted into the closed incubator along the connecting ring again, the air tightness of the device can be improved under the action of the rubber mat, the concentration of toxic gas in the incubator needs to be adjusted during toxicological experiments, the toxic gas can be filled into the device through the gas filling device, and then the toxic gas can be filled into the incubator. When the test is completed and the device is taken out, because the device is filled with toxic gas, the flowing direction of the gas can be switched through the adjusting assembly, and the toxic gas is guided into the filtering assembly, so that the gas is filtered and purified, and the toxicological cell culture box is relatively good in air tightness when being used; after the test, toxic gas used in the test can be conveniently filtered and purified, and the overall safety of the device is improved.

Description

Technical Field

[0001] This utility model relates to the field of biomedical technology, specifically to a toxicological cell culture box. Background Technology

[0002] Toxicology is an applied discipline that studies the harmful effects of exogenous factors (chemical, physical, and biological factors) on biological systems. It is the science that studies the toxic reactions, severity, frequency, and mechanisms of toxicity of chemical substances on organisms, and also the science of qualitative and quantitative evaluation of toxic effects. It is a discipline that predicts the harm to human health and the ecological environment, providing a scientific basis for determining safety limits and taking preventative measures. A cell culture incubator is a laboratory device used to culture, preserve, and propagate cells. It provides a controlled environment to promote cell growth and proliferation and is commonly used in experimental research in fields such as cell biology and molecular biology.

[0003] Traditional cell culture chambers can only provide basic temperature control and gas concentration requirements during use, lacking protective designs for toxicological experiments. This makes them prone to toxic gas leaks during and after toxicological experiments, resulting in low safety and difficulty in recovering and treating the waste gas generated during the experiments. Summary of the Invention

[0004] The purpose of this invention is to provide a toxicological cell culture chamber to solve the problems mentioned in the background art. Traditional cell culture chambers can only provide basic temperature control and gas concentration, lack protective design for toxicological tests, are prone to leakage of toxic gases during and after toxicological tests, have low safety, and are difficult to recycle and treat the waste gas generated during the test.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a toxicological cell culture chamber, comprising a working panel and support legs fixedly installed on both sides of the lower end of the working panel. A culture chamber is fixedly installed on the upper end of the working panel. A connecting ring is fixedly installed on the side wall of the culture chamber. A rubber pad is fixedly installed on the lower end of the connecting ring. A movable door is slidably installed on the connecting ring. A culture support is fixedly installed inside the culture chamber. A bidirectional fan is fixedly installed on the upper end of the culture chamber. An adjustment component, a filter component, and a gas filling device are respectively provided on the upper end of the culture chamber.

[0006] Preferably, the adjustment component includes a fixing block fixedly installed on the upper end of the incubator, and the fixing block has a sliding groove.

[0007] Preferably, an adjusting plug is slidably installed in the groove, the lower end of the adjusting plug has an opening, and the inner walls on both sides of the opening have connection ports.

[0008] Preferably, the upper and lower ends of the two sides of the fixing block are respectively provided with connecting pipe one and connecting pipe two. Connecting pipe one is connected to the gas filling device. A one-way valve is fixedly installed at the upper end of the gas filling device. Connecting pipe two is connected to the interior of the filter assembly.

[0009] Preferably, a connecting groove is provided on the side wall of the connecting pipe, a baffle is slidably installed in the connecting groove, a spring is fixedly installed between the lower wall of the baffle and the side wall of the connecting groove, and a protrusion is fixedly installed on the side wall of the baffle.

[0010] Preferably, a limiting rod is fixedly installed between the upper and lower walls of the connecting groove, the baffle is slidably connected to the limiting rod, the spring is sleeved on the outside of the limiting rod, and when the adjusting plug moves to the uppermost and lowermost ends of the side wall, the connecting port is respectively connected to the second connecting pipe and the first connecting pipe.

[0011] Compared with the prior art, the beneficial effects of this utility model are:

[0012] 1. First, remove the movable door and place the cultured cells on the culture rack. After placement, insert the movable door back into the sealed incubator along the connecting ring. The rubber pad increases the airtightness of the device. When conducting toxicology experiments, it is necessary to adjust the concentration of toxic gases inside the incubator. Toxic gases can be introduced into the device through the gas filling device. When removing the device after the experiment, since it is full of toxic gases, the flow direction of the gas can be switched by adjusting the component to guide the toxic gases into the filter component, thereby achieving gas filtration and purification. This toxicology cell culture chamber has good airtightness during use and facilitates the filtration and purification of toxic gases used in the experiment afterward, increasing the overall safety of the device.

[0013] 2. With the cooperation of the fixed block, connecting groove, baffle, protrusion, limiting rod, spring, slide, adjusting plug, opening, connecting port, connecting pipe one, connecting pipe two, filter assembly, gas filling device and one-way valve, when the device needs to be filled with toxic gas, moving the movable plug downward will automatically open connecting pipe one which is connected to the gas filling device, and moving the movable plug upward will automatically connect connecting pipe two which is connected to the filter assembly and automatically close connecting pipe one, thus realizing automatic switching. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall three-dimensional structure of this utility model;

[0015] Figure 2 This is a schematic diagram of the overall longitudinal cross-sectional three-dimensional structure of this utility model;

[0016] Figure 3This is a schematic diagram of the overall transverse cross-sectional three-dimensional structure of this utility model;

[0017] Figure 4 For the present utility model Figure 3 Enlarged 3D structural diagram at point A.

[0018] In the diagram: 1. Working panel; 2. Support leg; 3. Incubator; 31. Connecting ring; 32. Rubber pad; 4. Movable door; 5. Culture support; 6. Two-way fan; 7. Adjustment assembly; 71. Fixing block; 710. Connecting groove; 711. Baffle; 712. Protrusion; 713. Limiting rod; 714. Spring; 72. Slide groove; 73. Adjusting plug; 74. Opening; 75. Connection port; 76. Connecting pipe one; 77. Connecting pipe two; 8. Filter assembly; 9. Gas filling device; 91. One-way valve. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] Example 1: Please refer to Figure 1 - Figure 3 A toxicology cell culture chamber includes a working panel 1 and support legs 2 fixedly installed on both sides of the lower end of the working panel 1. A culture chamber 3 is fixedly installed on the upper end of the working panel 1. A connecting ring 31 is fixedly installed on the side wall of the culture chamber 3. A rubber pad 32 is fixedly installed on the lower end of the connecting ring 31. A movable door 4 is slidably installed on the connecting ring 31. A culture support 5 is fixedly installed inside the culture chamber 3. A bidirectional fan 6 is fixedly installed on the upper end of the culture chamber 3. An adjustment component 7, a filter component 8, and a gas filling device 9 are respectively provided on the upper end of the culture chamber 3.

[0021] In this embodiment: When using this device to conduct cell toxicology culture experiments, the movable door 4 can be pulled down first, and then the cultured cells to be tested can be placed on the culture support 5. After placement, the movable door 4 can be inserted back into the closed incubator 3 along the connecting ring 31. The rubber pad 32 can increase the airtightness of the device. When conducting toxicology experiments, it is necessary to adjust the concentration of toxic gas inside the incubator 3. Toxic gas can be introduced into the device through the gas filling device 9. When the device is removed after the experiment, since it is full of toxic gas, the gas flow direction can be switched by adjusting component 7 to introduce the toxic gas into the filter component 8 to achieve gas filtration and purification. This toxicology cell culture chamber has good airtightness during use and facilitates the filtration and purification of toxic gases used in the experiment after the experiment, increasing the overall safety of the device.

[0022] Example 2: This example is an improvement on Example 1. For details, please refer to [link / reference]. Figure 2 - Figure 4 The adjustment component 7 includes a fixing block 71 fixedly installed on the upper end of the incubator 3. The fixing block 71 has a sliding groove 72, and the lower end of the sliding groove 72 is directly opposite to the bidirectional fan 6.

[0023] An adjusting plug 73 is slidably installed in the chute 72. An opening 74 is provided at the lower end of the adjusting plug 73. Connection ports 75 are provided on the inner sidewalls of both sides of the opening 74. The connection ports 75 can be used to connect to the filter components 8 or the gas filling device 9 on both sides.

[0024] The upper and lower ends of the two sides of the fixing block 71 are respectively provided with connecting pipe 1 76 and connecting pipe 2 77. Connecting pipe 1 76 is connected to the gas charging device 9. A one-way valve 91 is fixedly installed at the upper end of the gas charging device 9. Connecting pipe 2 77 is connected to the interior of the filter assembly 8. The gas charging device 9 and the filter assembly 8 can be connected through connecting pipe 1 76 and connecting pipe 2 77 respectively.

[0025] A connecting groove 710 is provided on the side wall of the connecting pipe 76. A baffle 711 is slidably installed in the connecting groove 710. A spring 714 is fixedly installed between the lower wall of the baffle 711 and the side wall of the connecting groove 710. A protrusion 712 is fixedly installed on the side wall of the baffle 711. When the adjusting plug 73 moves downward, it will contact the protrusion 712, causing the baffle 711 to slide downward and open the connecting pipe 76.

[0026] A limiting rod 713 is fixedly installed between the upper and lower walls of the connecting groove 710. The baffle 711 is slidably connected to the limiting rod 713. The spring 714 is sleeved on the outside of the limiting rod 713. When the adjusting plug 73 moves to the uppermost and lowermost ends, the connecting port 75 on the side wall is connected to the second connecting pipe 77 and the first connecting pipe 76, respectively. The spring 714 can automatically raise the baffle 711 to the position of blocking the first connecting pipe 76 when it is not squeezed by the movable plug 73.

[0027] In this embodiment: When it is necessary to fill the incubator 3 with toxic gas for a culture experiment, the movable plug 73 can be slid down along the slide groove 72. When the movable plug 73 slides down, it contacts the protrusion 712 on the side wall of the connecting pipe 76 and drives the protrusion 712 to move down. When the protrusion 712 moves down, it drives the baffle 711 to slide along the connecting groove 710. When it moves to the maximum distance that the movable plug 73 can move, the side opening of the connecting pipe 76 is directly opposite the connecting port 75 and is in a connected state. At this time, gas can be filled into the gas filling device 9 through the one-way valve 91, and the toxic gas is introduced into the interior of the incubator 3 along the connecting pipe 76. Under the action of the bidirectional fan 6, the gas flow can be accelerated, making the toxic gas diffusion more uniform. After the toxicology test is completed, the movable plug 73 can be pulled upwards. As the movable plug 73 moves upwards along the flower bed 72, the baffle 711 on the side wall is lifted back to its original position under the action of the spring 714, blocking the connecting pipe 1 76. When it is moved to the uppermost movable end, the connecting port 75 on the other side is connected to the connecting pipe 2 77. At this time, the gas can be filtered and discharged from the filter assembly 8 by the bidirectional fan 6. When the device is in use, if toxic gas needs to be filled, the movable plug 73 can be moved downwards to automatically open the connecting pipe 1 76 connected to the gas filling device 9. Moving the movable plug 73 upwards will automatically connect the connecting pipe 2 77 connected to the filter assembly 8 and automatically close the connecting pipe 1 76, realizing automatic switching.

[0028] The contents not described in detail in this specification are existing technologies known to those skilled in the art.

[0029] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A toxicology cell culture chamber, comprising a working panel (1) and support legs (2) fixedly installed on both sides of the lower end of the working panel (1), wherein a culture chamber (3) is fixedly installed on the upper end of the working panel (1), characterized in that: A connecting ring (31) is fixedly installed on the side wall of the incubator (3), a rubber pad (32) is fixedly installed at the lower end of the connecting ring (31), a movable door (4) is slidably installed on the connecting ring (31), a culture support (5) is fixedly installed inside the incubator (3), a bidirectional fan (6) is fixedly installed at the upper end of the incubator (3), and an adjustment component (7), a filter component (8) and a gas filling device (9) are respectively provided at the upper end of the incubator (3).

2. The toxicological cell culture incubator according to claim 1, characterized in that: The adjustment component (7) includes a fixing block (71) fixedly installed on the upper end of the incubator (3), and the fixing block (71) is provided with a sliding groove (72).

3. The toxicological cell culture incubator according to claim 2, characterized in that: An adjusting plug (73) is slidably installed in the groove (72). An opening (74) is provided at the lower end of the adjusting plug (73), and a connection port (75) is provided on both sides of the inner wall of the opening (74).

4. A toxicological cell culture incubator according to claim 3, characterized in that: The upper and lower ends of the two sides of the fixed block (71) are respectively provided with connecting pipe one (76) and connecting pipe two (77). The connecting pipe one (76) is connected to the gas filling device (9). A one-way valve (91) is fixedly installed at the upper end of the gas filling device (9). The connecting pipe two (77) is connected to the interior of the filter assembly (8).

5. A toxicological cell culture incubator according to claim 4, characterized in that: The side wall of the connecting pipe (76) is provided with a connecting groove (710), and a baffle (711) is slidably installed in the connecting groove (710). A spring (714) is fixedly installed between the lower wall of the baffle (711) and the side wall of the connecting groove (710). A protrusion (712) is fixedly installed on the side wall of the baffle (711).

6. A toxicological cell culture incubator according to claim 5, characterized in that: A limiting rod (713) is fixedly installed between the upper and lower walls of the connecting groove (710). The baffle (711) is slidably connected to the limiting rod (713). The spring (714) is sleeved on the outside of the limiting rod (713). When the adjusting plug (73) moves to the uppermost and lowermost ends, the connecting port (75) is connected to the second connecting pipe (77) and the first connecting pipe (76) respectively.

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