Liquid-based thin-layer cell flaking and dyeing all-in-one machine

Abstract

The utility model relates to the technical field of medical instruments, and discloses a liquid-based thin-layer cell slide making and dyeing all-in-one machine which comprises a machine body, a telescopic rod is fixedly connected to the top of the inner wall of the machine body, a ventilation plate is fixedly connected to the bottom end of the telescopic rod, and a plurality of sliding rods are fixedly connected to the left side and the right side of the bottom end of the ventilation plate. A sample frame is fixedly connected to the bottom end of the sliding rod, a test tube is slidably connected to the inner wall of the sample frame, an air pump is fixedly communicated with the left side of the top of the ventilation plate, a plurality of limiting frames are fixedly connected to the left side and the right side of the bottom end of the sample frame, and a plurality of spraying heads are fixedly communicated with the front side and the rear side of the bottom end of the sample frame. According to the utility model, the telescopic rod is started to enable the ventilation plate to slide downwards and drive the sample frame to move downwards, the sample frame stops when the limiting frame touches the slide preparation plate, the ventilation plate seals the test tube to inflate, and sample liquid is uniformly sprayed on a glass slide from the spray head, so that the rapid and uniform slide preparation effect is realized, the efficiency is improved, and the requirements are met.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a liquid-based thin-layer cell preparation and staining machine. Background Technology

[0002] In the medical field, early and accurate diagnosis of diseases plays a crucial role in improving treatment outcomes and patient prognosis. The liquid-based thin-layer cell preparation and staining machine has emerged to address this need, with profound implications. As society develops and people place increasing emphasis on health, higher demands are being placed on the accuracy and efficiency of disease screening and diagnosis. In the early diagnosis of major cancer-related diseases, cellular morphology examination is a critical step. The liquid-based thin-layer cell preparation and staining machine can process cell samples and produce high-quality smears, providing doctors with clear and accurate cell morphology information, greatly assisting in the early diagnosis of diseases. It has an undeniable value in improving overall medical standards and safeguarding public health.

[0003] Currently, cell preparation and staining primarily rely on manual operation. Doctors must first collect samples, then manually transfer cells onto glass slides, and then perform each staining step sequentially. This method is not only labor-intensive and time-consuming, but also prone to uneven cell distribution and residual impurities due to variations in operator technique, affecting observation and reducing the accuracy of diagnostic results. Existing staining equipment has automated the processing, preparation, and staining processes, reducing manual intervention and improving efficiency. However, these devices still have many drawbacks. Some equipment has a complex slide preparation process, requiring extensive preparatory and debugging work by professionals, increasing operational difficulty and the probability of errors, and reducing the uniformity of the slides. The staining step needs to be performed separately and cannot be processed quickly, resulting in low efficiency in sample processing and difficulty in meeting the sample testing requirements. Utility Model Content

[0004] To overcome the above shortcomings, this utility model provides a liquid-based thin-layer cell preparation and staining integrated machine, which aims to improve the problems of complex preparation process and uneven application of cell suspension in the existing technology, resulting in poor sample quality and low efficiency.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a liquid-based thin-layer cell preparation and staining integrated machine, comprising a machine body, a telescopic rod fixedly connected to the top of the inner wall of the machine body, a venting plate fixedly connected to the bottom end of the telescopic rod, multiple sliding rods fixedly connected to the left and right sides of the bottom end of the venting plate, a sample rack fixedly connected to the bottom end of the sliding rods, test tubes slidably connected to the inner wall of the sample rack, an air pump fixedly connected to the top left side of the venting plate, multiple limiting frames fixedly connected to the left and right sides of the bottom end of the sample rack, multiple spray heads fixedly connected to the front and rear sides of the bottom end of the sample rack, a slide preparation plate fixedly connected to the bottom of the inner wall of the machine body, multiple glass slides arranged on the top of the slide preparation plate, and a staining mechanism arranged on the top of the slide preparation plate, the staining mechanism being used for automatic staining.

[0006] As a further description of the above technical solution:

[0007] The dyeing mechanism includes a heating plate, the outer wall of which is set on the inner wall of the sheet preparation plate. Multiple flow baffles are fixedly connected to the front and rear sides of the top of the machine body. A water pipe is fixedly connected to the right side of the left flow baffle, and a dyeing solution tank is fixedly connected to the right side of the water pipe. An automatic valve is provided on the top of the outer wall of the water pipe. Multiple drainage holes are opened on the front side of the flow baffle. A scraper is slidably connected to the rear side of the inner wall of the flow baffle. A sliding column is fixedly connected to the rear end of the scraper, and a spring is provided on the outer wall of the sliding column.

[0008] As a further description of the above technical solution:

[0009] A controller is fixedly connected to the middle of the front right side of the machine body, and a display screen is fixedly connected to the left front side of the controller.

[0010] As a further description of the above technical solution:

[0011] Multiple buttons are fixedly connected to the top right side of the front of the controller, and a power button is fixedly connected to the bottom right side of the front of the controller.

[0012] As a further description of the above technical solution:

[0013] A nameplate is fixedly connected to the top right side of the front of the machine body, and multiple fixing posts are fixedly connected to the left and right sides of the front of the nameplate.

[0014] As a further description of the above technical solution:

[0015] A protective plate is fixedly connected to the top of the machine body, and a support platform is fixedly connected to the bottom of the machine body.

[0016] As a further description of the above technical solution:

[0017] Multiple decorative strips are fixedly connected to the left and right sides of the front of the support platform, and the multiple decorative strips are arranged at equal intervals.

[0018] As a further description of the above technical solution:

[0019] The bottom of each support platform is fixedly connected to multiple support columns, and the bottom of each support column is fixedly connected to a support foot.

[0020] This utility model has the following beneficial effects:

[0021] 1. In this utility model, the sample tube is placed in the sample rack, the telescopic rod is activated to make the vent plate slide down, which drives the slide rod and the sample rack to move downward. When the limit frame of the sample rack touches the slide plate, it stops. The vent plate continues to squeeze the top of the test tube, and the air pump is activated to inflate the test tube. The sample liquid is evenly sprayed onto the glass slide through the spray head, achieving a fast and uniform slide preparation effect, improving efficiency and meeting the needs of use.

[0022] 2. In this utility model, the heating plate is installed on the inner wall of the preparation plate to quickly dry the sprayed sample, which is convenient for dyeing. When the automatic valve is opened, the dye in the dye bath flows into the baffle frame through the water pipe to dye the sample. After dyeing, the dye flows out through the drain hole. The scraper, slide column and spring work together to automatically clean the liquid on the wall, realizing automatic dyeing and dye discharge, improving the convenience of operation and meeting the dyeing needs. Attached Figure Description

[0023] Figure 1 This is a three-dimensional view of the front side of the liquid-based thin-layer cell preparation and staining integrated machine proposed in this utility model;

[0024] Figure 2 This is a partial structural disassembly diagram of the sample rack of a liquid-based thin-layer cell preparation and staining integrated machine proposed in this utility model;

[0025] Figure 3 This is a partial structural diagram of the slide preparation plate of a liquid-based thin-layer cell preparation and staining integrated machine proposed in this utility model;

[0026] Figure 4 This is a partial structural diagram of the flow baffle of a liquid-based thin-layer cell preparation and staining integrated machine proposed in this utility model;

[0027] Figure 5 This is a partial structural diagram of the support platform of the liquid-based thin-layer cell preparation and staining integrated machine proposed in this utility model.

[0028] Legend:

[0029] 1. Main body; 2. Staining mechanism; 201. Heating plate; 202. Baffle; 203. Water pipe; 204. Dye tank; 205. Automatic valve; 206. Drain hole; 207. Scraper; 208. Sliding column; 209. Spring; 3. Telescopic rod; 4. Ventilation plate; 5. Sliding rod; 6. Sample rack; 7. Test tube; 8. Air pump; 9. Limiting frame; 10. Spray head; 11. Slide preparation plate; 12. Glass slide; 13. Controller; 14. Display screen; 15. Button; 16. Power button; 17. Nameplate; 18. Fixing column; 19. Protective plate; 20. Support platform; 21. Decorative strip; 22. Support column; 23. Support foot. Detailed Implementation

[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0031] Please see the appendix Figure 1 Appendix Figure 2 and attached Figure 3 An embodiment of this utility model provides: a liquid-based thin-layer cell preparation and staining integrated machine, including a body 1, a telescopic rod 3 fixedly connected to the top of the inner wall of the body 1, a ventilation plate 4 fixedly connected to the bottom end of the telescopic rod 3, multiple sliding rods 5 fixedly connected to the left and right sides of the bottom end of the ventilation plate 4, a sample rack 6 fixedly connected to the bottom end of the sliding rods 5, test tubes 7 slidably connected to the inner wall of the sample rack 6, an air pump 8 fixedly connected to the top left side of the ventilation plate 4, multiple limiting frames 9 fixedly connected to the left and right sides of the bottom end of the sample rack 6, multiple spray heads 10 fixedly connected to the front and rear sides of the bottom end of the sample rack 6, a slide preparation plate 11 fixedly connected to the bottom of the inner wall of the body 1, multiple glass slides 12 arranged on the top of the slide preparation plate 11, and a staining mechanism 2 arranged on the top of the slide preparation plate 11, the staining mechanism 2 being used for automatic staining;

[0032] Specifically, a telescopic rod 3 is fixedly connected to the top of the inner wall of the body 1. The bottom end of the telescopic rod 3 is fixedly connected to the ventilation plate 4, ensuring smooth movement of the ventilation plate 4. Multiple sliding rods 5 are provided on both the left and right sides of the bottom of the ventilation plate 4. The bottom ends of these sliding rods 5 are fixedly connected to the sample holder 6, allowing the sample holder 6 to slide along with the ventilation plate 4 under gravity. The inner wall of the sample holder 6 can slidably accommodate test tubes 7 for sample processing. The top left side of the ventilation plate 4 is fixedly connected... Connected to the air pump 8, which provides the necessary airflow to pressurize the test tube 7, the limiting frames 9 ensure the stability of the sample rack 6 during sliding. Multiple spray heads 10 are fixedly connected to the front and rear sides of the bottom of the sample rack 6. The spray heads 10 are used to evenly spray the sample onto the glass slide 12 during sample processing. Multiple glass slides 12 are on the slide preparation plate 11 for slide preparation and staining. The staining mechanism 2 is an automatic staining device that can automatically complete the staining process of the sample, improve experimental efficiency, and reduce human error.

[0033] Please see the appendix Figure 1 Appendix Figure 3 and attached Figure 4 The dyeing mechanism 2 includes a heating plate 201. The outer wall of the heating plate 201 is set on the inner wall of the sheet preparation plate 11. Multiple baffles 202 are fixedly connected to the front and rear sides of the top of the machine body 1. A water pipe 203 is fixedly connected to the right side of the left baffle 202. A dyeing liquid tank 204 is fixedly connected to the right side of the water pipe 203. An automatic valve 205 is set on the top of the outer wall of the water pipe 203. Multiple drain holes 206 are opened on the front side of the baffle 202. A scraper 207 is slidably connected to the rear side of the inner wall of the baffle 202. A sliding column 208 is fixedly connected to the rear end of the scraper 207. A spring 209 is set on the outer wall of the sliding column 208.

[0034] Specifically, the heating plate 201 is attached to the inner wall of the slide preparation plate 11, ensuring effective heat transfer and accelerating sample drying. The baffles 202 contain the dye solution, ensuring uniformity during the staining process. The water pipe 203 is responsible for delivering the dye solution to the staining area. A dye solution tank 204 is fixedly connected to the right side of the water pipe 203, storing sufficient dye solution for the entire staining process. To control the flow of the dye solution, an automatic valve 205 is installed on the top of the outer wall of the water pipe 203. This automatic valve 205 can precisely control the flow rate of the dye solution. Multiple drainage holes 206 are provided on the front side of the flow baffle 202. These drainage holes 206 ensure that the dye liquor can be discharged in time after dyeing, avoiding waste and contamination of the dye liquor. In order to further improve the dyeing efficiency, a scraper 207 is slidably connected to the rear side of the inner wall of the flow baffle 202. The function of the scraper 207 is to scrape off excess dye liquor. A sliding column 208 is fixedly connected to the rear end of the scraper 207. A spring 209 is provided on the outer wall of the sliding column 208. The presence of the spring 209 allows the scraper 207 to apply appropriate pressure as needed, thereby achieving the best dyeing effect.

[0035] Please see the appendix Figure 1 and attached Figure 5 A controller 13 is fixedly connected to the middle right front of the body 1. A display screen 14 is fixedly connected to the left front of the controller 13. Multiple buttons 15 are fixedly connected to the top right front of the controller 13. A power button 16 is fixedly connected to the bottom right front of the controller 13. A nameplate 17 is fixedly connected to the top right front of the body 1. Multiple fixing posts 18 are fixedly connected to the left and right front sides of the nameplate 17.

[0036] Specifically, the controller 13 on the main body 1 ensures that the device can operate according to the program. There is a display screen 14 on the front left of the controller 13 so that users can intuitively view various information and operation interface. Multiple buttons 15 on the top right of the front of the controller 13 are evenly fixedly connected to the corresponding positions of the controller 13 to provide users with a convenient way to operate. The power button 16 allows users to turn the entire device on and off. In order to enhance the product's recognition and aesthetics, a nameplate 17 is fixedly connected to the top right of the front of the main body 1. The nameplate 17 can display the product's brand information and model identification. In order to ensure the stability of the nameplate 17, multiple fixing posts 18 are fixedly connected to the left and right sides of its front. These fixing posts 18 not only ensure the stability of the nameplate 17, but also provide additional support for the structural strength of the entire main body 1.

[0037] Please see the appendix Figure 1A protective plate 19 is fixedly connected to the top of the body 1, and a support platform 20 is fixedly connected to the bottom of the body 1. Multiple decorative strips 21 are fixedly connected to the left and right sides of the front of the support platform 20. The multiple decorative strips 21 are arranged at equal intervals. Multiple support columns 22 are fixedly connected to the bottom of the support platform 20. Support feet 23 are fixedly connected to the bottom of the support columns 22.

[0038] Specifically, the top of the body 1 is fixedly connected to the protective plate 19, which can effectively protect the upper part of the body 1 from damage by external factors. The bottom of the body 1 is fixedly connected to the support platform 20 to ensure the stability of the entire structure. These decorative strips 21 not only serve an aesthetic purpose, but also enhance the overall coordination and visual effect through their equidistant arrangement. Multiple support columns 22 are also fixedly connected to the bottom of the support platform 20. These support columns 22 further enhance the stability and load-bearing capacity of the entire structure. In order for the support columns 22 to be firmly supported on the ground, support feet 23 are also fixedly connected to their bottom ends, which can effectively distribute pressure and ensure the stability and durability of the support structure.

[0039] Working principle: The test tube 7 containing the sample is placed into the sample holder 6. The telescopic rod 3 on the machine body 1 is activated, causing the vent plate 4 to slide downward. The inner wall of the vent plate 4 is slidably connected to the slide rod 5, and the bottom end of the slide rod 5 is fixedly connected to the sample holder 6, causing the sample holder 6 to move downward. When the limiting frame 9 at the bottom of the sample holder 6 contacts the slide preparation plate 11, the sample holder 6 stops moving. The vent plate 4 continues to slide downward, squeezing and sealing the top of the test tube 7. At this time, the air pump 8 connected to the top of the vent plate 4 is activated to inflate the inside of the test tube 7. Since the bottom end of the test tube 7 is connected to the spray head 10 fixedly connected to the bottom end of the sample holder 6 when the test tube 7 is installed on the sample holder 6, the sample liquid is evenly sprayed onto the glass slide 12. This structure can quickly and evenly spray the sample onto the glass slide 12, improving the slide preparation effect and efficiency, and meeting the usage requirements.

[0040] A heating plate 201 is installed on the inner wall of the slide preparation plate 11, allowing the sample sprayed inside the baffle 202 to dry quickly for the staining step. During staining, the automatic valve 205 opens, and due to the enclosure of the baffle 202, the staining solution in the staining tank 204 flows into the area enclosed by the baffle 202 through the water pipe 203 to stain the slide. After staining, the finished product is removed so that the drain hole 206 is no longer blocked, and the staining solution flows out from the drain hole 206. The scraper 207, which is slidably connected to the inner wall of the baffle 202, is fixedly connected to the sliding column 208 that works with the spring 209, so that after removal, the scraper 207 scrapes the wall to clean the liquid. This structure can automatically perform the staining operation and automatically discharge the used staining solution, improving the convenience of operation and meeting the staining requirements.

[0041] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A liquid-based thin-layer cell preparation and staining integrated machine, comprising a machine body (1), characterized in that: The inner wall top of the machine body (1) is fixedly connected with a telescopic rod (3), the bottom end of the telescopic rod (3) is fixedly connected with a ventilation plate (4), the bottom end of the ventilation plate (4) is fixedly connected with a plurality of slide rods (5) on the left and right sides, the bottom end of the slide rod (5) is fixedly connected with a sample rack (6), the inner wall of the sample rack (6) is slidably connected with a test tube (7), the top left side of the ventilation plate (4) is fixedly connected with an air pump (8), the bottom end of the sample rack (6) is fixedly connected with a plurality of limiting frames (9) on the left and right sides, the bottom end of the sample rack (6) is fixedly connected with a plurality of spray heads (10) on the front and back sides, the inner wall bottom of the machine body (1) is fixedly connected with a slide plate (11), a plurality of glass slides (12) are arranged on the top of the slide plate (11), and a dyeing mechanism (2) is arranged on the top of the slide plate (11). The dyeing mechanism (2) is used for automatic dyeing.

2. The liquid-based thin-layer cell preparation, staining and dyeing integrated machine according to claim 1, characterized in that: The dyeing mechanism (2) comprises a heating plate (201), the outer wall of the heating plate (201) is arranged on the inner wall of the slide plate (11), a plurality of flow blocking frames (202) are fixedly connected to the top end of the machine body (1) on the front and back sides, a water pipe (203) is fixedly connected to the right side of the left flow blocking frame (202), the right side of the water pipe (203) is fixedly connected with a dye solution tank (204), an automatic valve (205) is arranged on the outer wall top of the water pipe (203), a plurality of liquid discharge holes (206) are formed in the front side of the flow blocking frame (202), a scraper (207) is slidably connected to the rear side of the inner wall of the flow blocking frame (202), the rear end of the scraper (207) is fixedly connected with a slide column (208), and the outer wall of the slide column (208) is provided with a spring (209).

3. The liquid-based thin-layer cell preparation and staining integrated machine according to claim 1, characterized in that: The front end right side of the machine body (1) is fixedly connected with a controller (13), and the front end left side of the controller (13) is fixedly connected with a display screen (14).

4. The liquid-based thin-layer cell preparation, staining and dyeing integrated machine according to claim 3, characterized in that: The front end right side of the controller (13) is fixedly connected with a plurality of buttons (15) on the top, and the front end right side of the controller (13) is fixedly connected with a power key (16) on the bottom.

5. The liquid-based thin-layer cell preparation and staining integrated machine according to claim 1, characterized in that: The front end right side of the machine body (1) is fixedly connected with a nameplate (17) on the top, and the front side left and right sides of the nameplate (17) are fixedly connected with a plurality of fixed columns (18).

6. The liquid-based thin-layer cell preparation and staining integrated machine according to claim 1, characterized in that: The top of the machine body (1) is fixedly connected with a protection plate (19), and the bottom of the machine body (1) is fixedly connected with a support table (20).

7. The liquid-based thin-layer cell preparation and staining integrated machine according to claim 6, characterized in that: The front side left and right sides of the support table (20) are fixedly connected with a plurality of decorative strips (21), and the plurality of decorative strips (21) are arranged at equal intervals.

8. The liquid-based thin-layer cell preparation and staining integrated machine according to claim 6, characterized in that: The bottom end of the support table (20) is fixedly connected with a plurality of support columns (22), and the bottom end of the support column (22) is fixedly connected with a support foot (23).

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