Multi-typing detection kit for detecting human papilloma virus

Abstract

The utility model discloses a multi-parting detection kit for human papilloma virus detection, which comprises a kit body, an opening is arranged on the upper side of the kit body, a kit cover is hinged on one side of the opening, four buffer components are mounted at the bottom of the kit body, parting support plates are mounted among the four buffer components, and the parting support plates are hinged on the upper side of the kit body. A parting inserting plate is installed on the upper side of the parting supporting plate, and a plurality of clamping assemblies are arranged on the parting inserting plate in an array mode. Wherein the clamping assembly comprises an inserting groove located in a parting inserting plate, a test tube is inserted into the inserting groove till the bottom end of the test tube abuts against the interior of a concave groove, a pressing ring is screwed, the pressing ring drives an inner threaded barrel to spirally move downwards along an outer threaded barrel, the inner wall of the pressing ring extrudes inclined faces of triangular plates, and the outer wall of the test tube is jointly clamped by the multiple triangular plates; the device is simple in structure, easy to operate and control, suitable for test tubes with different diameters, high in universality and capable of ensuring that the test tubes cannot loosen or shift in the shaking or transporting process.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a multi-genotyping test kit for human papillomavirus (HPV) detection. Background Technology

[0002] Human papillomavirus (HPV) is a group of DNA viruses belonging to the Papillomaviridae family that can infect human skin and mucous membranes. Currently, there are various methods for HPV detection, including PCR (polymerase chain reaction), hybridization capture method, gene chip, sequencing, etc. Each method can achieve HPV genotyping detection. The specific choice should be based on a comprehensive consideration of factors such as testing needs, sample type, and laboratory conditions.

[0003] Chinese Patent Publication No. CN209652346U discloses a human papillomavirus (HPV) DNA typing detection kit, comprising a box body and a lid connected to the box body. The box body has an elastic fixing body with multiple fixing grooves. Each fixing groove contains a DNA extraction solution bottle, a Taq / UNG enzyme mixture tube, a first PCR reaction solution tube, a second PCR reaction solution tube, a third PCR reaction solution tube, a fourth PCR reaction solution tube, a fifth PCR reaction solution tube, a sixth PCR reaction solution tube, a seventh PCR reaction solution tube, a positive control tube, and a negative control tube. All bottles and tubes are capped. The lower inner wall of each fixing groove has positioning protrusions, and the lower wall of the DNA extraction solution bottle and the lower wall of each tube have positioning recesses that mate with the positioning protrusions. This novel kit can simultaneously detect 28 DNA types of human papillomavirus, providing important guidance for clinical practice.

[0004] The above-mentioned technology has limited adaptability to test tubes of different diameters and poor buffering effect. Under violent shaking, the test tube is very easy to fall out of the fixing groove, resulting in damage and leakage. Therefore, this utility model discloses a multi-genotyping detection kit for human papillomavirus detection to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a multi-genotyping test kit for human papillomavirus (HPV) detection, in order to solve the problems mentioned in the background art: the traditional test kits have limited adaptability to test tubes of different diameters, poor buffering effect, and the test tubes are easily dislodged from the fixing groove under violent shaking, resulting in damage and leakage.

[0006] To achieve the above objectives, the present invention provides the following solution to the aforementioned technical problems:

[0007] A multigenotyping test kit for human papillomavirus detection includes a box body with an opening on the upper side of the box body. A box cover is hinged to one side of the opening. Four buffer components are installed at the bottom of the box body. A genotyping tray is installed between the four buffer components. A genotyping insert is installed on the upper side of the genotyping tray. Multiple clamping components are arranged in an array on the genotyping insert.

[0008] The clamping assembly includes a slot located on a parting plate. An external threaded cylinder is fixedly connected to the slot and located on the parting plate. An internal threaded cylinder is threadedly connected to the outer side of the external threaded cylinder. A pressure ring is fixedly connected to the top of the internal threaded cylinder. Multiple elastic clamping plates are equidistantly arranged on the edge of the slot. A triangular plate is provided at the end of the elastic clamping plate away from the slot. A test tube is clamped between the triangular plates.

[0009] As a further embodiment of this utility model, the buffer assembly includes a vertical rod slidably embedded in the parting tray. The bottom end of each vertical rod is fixedly connected to the bottom wall of the box, and the top end of each vertical rod is fixedly connected to a baffle. Springs are sleeved on the outer side of each vertical rod and on the upper and lower sides of the parting tray.

[0010] As a further embodiment of this utility model, a silicone pad is glued and fixed on the upper side of the parting tray and at the position directly opposite the slot, and a recessed groove is provided on the side of the silicone pad away from the parting tray.

[0011] As a further embodiment of this utility model, support rods are fixedly connected to the upper sides of the four corners of the parting tray, and parting inserts are fixedly connected between the top ends of the four support rods.

[0012] As a further embodiment of this utility model, a transparent glass is fixedly embedded in the middle of the box cover, and a rubber pad is fixedly connected around the transparent glass and located inside the box cover.

[0013] As a further embodiment of this utility model, a card plate is fixedly connected to one side of the box body, and an elastic plate is provided at the position corresponding to the card plate on the box cover. The elastic plate is provided with a card hole that is adapted to the card plate.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] This invention relates to a multi-genotyping test kit for human papillomavirus (HPV) detection. The test tube is inserted into the slot until the bottom of the tube abuts against the recessed groove. Twisting the pressure ring causes the internal threaded cylinder to spiral downwards along the external threaded cylinder. The inner wall of the pressure ring presses against the inclined surface of the triangular plates, causing multiple triangular plates to clamp the outer wall of the test tube. The operation is simple and easy to control, suitable for test tubes of different diameters, and has strong versatility. It ensures that the test tube will not loosen or shift during shaking or transportation.

[0016] This invention relates to a multigenotyping test kit for human papillomavirus (HPV) detection. The spring in the buffer assembly can absorb the impact force through its own elastic deformation when the box is shaken or subjected to external impact, reducing the direct vibration of the test tube and thus protecting the sample inside the test tube from damage. Furthermore, the user can directly observe the condition of the test tube through the transparent glass during transportation or operation, which can significantly reduce the risk of sample leakage or test tube breakage caused by accidental collisions during transportation or operation. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments:

[0018] Figure 1 This is a schematic diagram illustrating a multi-genotyping detection kit for human papillomavirus (HPV) detection according to the present invention.

[0019] Figure 2 This is a front sectional view of a multi-genotyping detection kit for human papillomavirus (HPV) detection according to the present invention.

[0020] Figure 3 This invention relates to a multigenotyping detection kit for human papillomavirus (HPV) detection. Figure 2 Enlarged view of the structure at point A in the middle;

[0021] Figure 4 This invention relates to a multigenotyping detection kit for human papillomavirus (HPV) detection. Figure 2 Enlarged view of the structure at point B;

[0022] Figure 5 This is a structural diagram of the typing insert in a multi-type detection kit for human papillomavirus detection according to the present invention.

[0023] The components represented by each number in the attached diagram are listed below: 1. Box body; 11. Clamping plate; 2. Box lid; 21. Transparent glass; 22. Rubber pad; 23. Elastic plate; 24. Clamping hole; 3. Buffer assembly; 31. Vertical rod; 32. Baffle; 33. Spring; 4. Parting plate; 41. Silicone pad; 411. Recessed groove; 42. Support rod; 5. Parting insert plate; 6. Clamping assembly; 61. Slot; 62. External threaded cylinder; 63. Internal threaded cylinder; 631. Pressure ring; 64. Elastic clamping plate; 641. Triangular plate. Detailed Implementation

[0024] The present invention will be further described below with reference to the embodiments.

[0025] Please see Figure 1-5This utility model provides a multi-genotyping test kit for human papillomavirus detection, including a box body 1, an opening on the upper side of the box body 1, a box cover 2 hinged to one side of the opening, a retaining plate 11 fixedly connected to one side of the box body 1, and an elastic plate 23 provided at the position corresponding to the retaining plate 11 on the box cover 2, and a retaining hole 24 adapted to the retaining plate 11 on the elastic plate 23.

[0026] Specifically, when the lid 2 is closed, the locking hole 24 on the elastic plate 23 will engage with the locking plate 11 on the box body 1, thereby firmly fixing the lid 2 to the box body 1 and preventing the lid 2 from accidentally loosening or falling off during transportation or use, so as to ensure that the test tubes are not contaminated. Conversely, by prying the elastic plate 23 outward, the locking hole 24 can be separated from the locking plate 11, and the lid 2 can be easily opened. The operation is simple and quick.

[0027] Furthermore, a transparent glass 21 is fixedly embedded in the middle of the box cover 2, and a rubber pad 22 is fixedly connected to the outer periphery of the transparent glass 21 and located inside the box cover 2;

[0028] Specifically, the transparent glass 21 allows users to visually inspect the condition of the test tubes inside the kit without opening the lid 2. This is very helpful for quickly checking whether the test tubes are damaged or whether the samples are leaking. It can significantly improve work efficiency, especially during transportation or when frequent checks are required. The rubber pad 22 can effectively seal the seam between the lid 2 and the box body 1, preventing dust, moisture or other contaminants from the external environment from entering the kit.

[0029] Furthermore, four buffer components 3 are installed at the bottom of the box body 1. Each buffer component 3 includes a vertical rod 31 that is slidably embedded in the parting tray 4. The bottom end of each vertical rod 31 is fixedly connected to the bottom wall of the box body 1, and the top end of each vertical rod 31 is fixedly connected to a baffle 32. Springs 33 are sleeved on the outer side of each vertical rod 31 and on the upper and lower sides of the parting tray 4.

[0030] Specifically, when the reagent kit is shaken or subjected to external impact, the spring 33 can absorb the impact force through its own elastic deformation, reducing the direct impact on the sample tray 4 and the test tube. The compression and extension of the spring 33 can effectively disperse the impact energy, protecting the sample in the test tube from damage. The baffle 32 can prevent the sample tray 4 from detaching from the vertical rod 31, ensuring the structural integrity of the buffer assembly 3.

[0031] Furthermore, a parting plate 4 is installed between the four buffer components 3, a parting insert plate 5 is installed on the upper side of the parting plate 4, a support rod 42 is fixedly connected to the upper side of each of the four corners of the parting plate 4, and a parting insert plate 5 is fixedly connected between the top ends of the four support rods 42.

[0032] Specifically, the function of the support rod 42 is to connect the parting plate 5 and the parting tray 4 and provide stable support. Preferably, the distance between the parting plate 5 and the parting tray 4 is two-thirds of the test tube length to ensure that the test tube is adequately positioned.

[0033] Furthermore, silicone pads 41 are glued and fixed on the upper side of the parting tray 4 and at the position directly opposite the slot 61, and the silicone pads 41 are provided with recessed grooves 411 on the side away from the parting tray 4.

[0034] Specifically, when inserting the test tube into the slot 61, the main function of the silicone pad 41 is to provide cushioning and protection. When the reagent kit is shaken or subjected to external impact, the silicone pad 41 can effectively reduce the direct impact on the bottom of the test tube, protecting the sample inside the test tube from damage. The height of the recessed groove 411 gradually increases from the center to the periphery, which can play a good guiding role when inserting the test tube, making it easy to place the test tube in the center. The recessed groove 411 can prevent the test tube from loosening or shifting during shaking or transportation.

[0035] Furthermore, multiple clamping components 6 are arranged in an array on the parting plate 5. Each clamping component 6 includes a slot 61 located on the parting plate 5. An external threaded cylinder 62 is fixedly connected to the periphery of the slot 61 and located on the parting plate 5. An internal threaded cylinder 63 is threadedly connected to the outer side of the external threaded cylinder 62. A pressure ring 631 is fixedly connected to the top of the internal threaded cylinder 63. Multiple elastic clamping plates 64 are equidistantly arranged on the edge of the slot 61. A triangular plate 641 is provided at the end of the elastic clamping plate 64 away from the slot 61. A test tube is clamped between the triangular plates 641.

[0036] Specifically, by turning the pressure ring 631, the internal threaded cylinder 63 spirals downwards along the external threaded cylinder 62. The inner wall of the pressure ring 631 presses against the inclined surface of the triangular plate 641, causing multiple triangular plates 641 to clamp the outer wall of the test tube together. This adjustable clamping method is not only simple to operate, but also ensures that the test tube will not loosen or shift during shaking or transportation. It can adapt to test tubes of different diameters, making the clamping component 6 widely applicable and reducing compatibility issues caused by differences in test tube size. Compared with existing technologies, which may only be compatible with a limited number of test tube sizes, this component can adapt to a wider range of diameters, reducing compatibility issues caused by differences in test tube size. During the transportation of medical test samples, this stable clamping can prevent sample leakage and cross-contamination, improving the accuracy of test results. In laboratory operations, its wide applicability can reduce the time spent changing different clamping tools and improve work efficiency.

[0037] Working principle:

[0038] In use, open the lid 2, insert the test tube into the slot 61 until the bottom of the test tube abuts against the recessed groove 411, and turn the pressure ring 631. The pressure ring 631 drives the internal threaded cylinder 63 to spiral down along the external threaded cylinder 62. The inner wall of the pressure ring 631 presses the inclined surface of the triangular plate 641, so that multiple triangular plates 641 clamp the outer wall of the test tube together. After closing the lid 2, it can be easily carried. When the lid 2 shakes, the parting plate 4 will be subjected to a certain impact force. At this time, the spring 33 can absorb this impact force through its own elastic deformation. The compression and extension of the spring 33 can effectively reduce the direct impact of shaking on the test tube, thereby protecting the sample inside the test tube from damage.

Claims

1. A multiplex detection kit for human papilloma virus detection, comprising a box body (1), the upper side of the box body (1) is provided with an open mouth, and the open mouth is hinged with a box cover (2) on one side, characterized in that, Four buffer components (3) are installed at the bottom of the box (1), and a parting tray (4) is installed between the four buffer components (3). A parting insert (5) is installed on the upper side of the parting tray (4), and multiple clamping components (6) are arranged in an array on the parting insert (5). The clamping assembly (6) includes a slot (61) located on the parting plate (5). An external threaded cylinder (62) is fixedly connected to the outer periphery of the slot (61) and on the parting plate (5). An internal threaded cylinder (63) is threadedly connected to the outer side of the external threaded cylinder (62). A pressure ring (631) is fixedly connected to the top of the internal threaded cylinder (63). Multiple elastic clamps (64) are equidistantly arranged on the edge of the slot (61). A triangular plate (641) is provided at the end of the elastic clamp (64) away from the slot (61). A test tube is clamped between the triangular plates (641).

2. The multiplex typing test kit for human papilloma virus detection according to claim 1, characterized in that: The buffer assembly (3) includes a vertical rod (31) that is slidably embedded in the parting tray (4). The bottom end of the vertical rod (31) is fixedly connected to the bottom wall of the box body (1). The top end of the vertical rod (31) is fixedly connected to a baffle (32). Springs (33) are sleeved on the outside of the vertical rod (31) and on the upper and lower sides of the parting tray (4).

3. The multiplex typing test kit for human papilloma virus detection according to claim 1, characterized in that: Silicone pads (41) are glued and fixed on the upper side of the parting tray (4) and at the position directly opposite the slot (61). The silicone pads (41) are provided with recessed grooves (411) on the side away from the parting tray (4).

4. The multiplex typing test kit for human papilloma virus detection according to claim 1, characterized in that: The four corners of the parting plate (4) are fixedly connected with support rods (42), and the top ends of the four support rods (42) are fixedly connected with parting inserts (5).

5. The multiplex typing test kit for human papilloma virus detection according to claim 1, characterized in that: A transparent glass (21) is fixedly embedded in the middle of the box cover (2), and a rubber pad (22) is fixedly connected to the outer periphery of the transparent glass (21) and located inside the box cover (2).

6. The multiplexed test kit for human papilloma virus detection according to claim 1, wherein: A card plate (11) is fixedly connected to one side of the box body (1), and an elastic plate (23) is provided on the box cover (2) at a position corresponding to the card plate (11). The elastic plate (23) has a card hole (24) adapted to the card plate (11).

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