Disposable filtering membrane bag

Abstract

The utility model discloses a disposable filtering membrane bag, which comprises a shell and a filtering assembly, the filtering assembly comprises a liquid inlet piece, a liquid permeable piece and a filtering layer, the liquid inlet piece and the liquid permeable piece are in sealing fit, and the filtering layer is clamped and positioned between the liquid inlet piece and the liquid permeable piece. The liquid inlet piece is provided with a liquid inlet and a liquid outlet which are communicated with the liquid inlet side of the filtering layer, and the liquid permeating piece is provided with a liquid permeating opening communicated with the liquid outlet side of the filtering layer. The utility model aims to effectively avoid pollutant residues caused by repeated use, reduce the risk of cross contamination, save the cleaning and sterilizing time and reduce the maintenance cost.

Description

Technical Field

[0001] This utility model belongs to the field of filtration technology, and in particular relates to a disposable filter membrane pack. Background Technology

[0002] Ultrafiltration (UF) is a membrane separation technology based on molecular weight cutoff. It separates large molecules (such as proteins and viruses) from small molecules (such as water and salts) in solution through a pressure-driven membrane with a pore size of 1-100 nm. Its core applications include concentration, desalination, fractionation purification, and virus removal in biopharmaceuticals. In particular, tangential flow filtration (TFF) mode can effectively alleviate membrane fouling and improve treatment efficiency.

[0003] Conventional tangential flow membrane packs typically employ a stacked design of multiple flat sheet membranes and screens, with membrane materials primarily consisting of polyethersulfone (PES) or regenerated cellulose (RC), characterized by high pressure and acid / alkali resistance. Traditional ultrafiltration systems often use reusable membrane modules (such as hollow fiber and spiral wound membranes), but residual contaminants can lead to batch-to-batch cross-contamination, threatening the production of high-value biopharmaceuticals (such as monoclonal antibodies and vaccines). To reduce residual contaminants, cleaning and sterilization are required, along with frequent cleaning validation (CIP / SIP), significantly increasing time and cost. Utility Model Content

[0004] This invention provides a disposable filter membrane pack that effectively avoids pollutant residue caused by repeated use, reduces the risk of cross-contamination, saves cleaning and sterilization time, and reduces maintenance costs.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A disposable filter membrane package includes a housing and a filter assembly. The filter assembly includes an inlet element, a permeate element, and a filter layer. The inlet element and the permeate element are sealed together. The filter layer is clamped and positioned between the inlet element and the permeate element. The inlet element has an inlet port and an outlet port communicating with the inlet side of the filter layer. The permeate element has a permeate port communicating with the outlet side of the filter layer. A single filter layer is arranged between the inlet element and the permeate element to form a filter membrane package structure. The filter membrane package is a disposable filter and cannot be reused, effectively avoiding the risk of contamination, saving cleaning and sterilization time in traditional ultrafiltration systems, and reducing maintenance costs. Furthermore, compared to multi-layer filter layers, it eliminates the need for through holes and sealing holes on the filter layers for series connection between multiple filter layers, improving the sealing effect of the membrane package structure, significantly reducing stagnant volume, avoiding material waste, and mitigating performance degradation.

[0007] Preferably, the side of the inlet component facing the filter layer has an inlet channel, which is connected to both the inlet and outlet. The inlet channel prevents the inlet component from adhering to the inlet surface of the filter layer, thus ensuring filtration efficiency.

[0008] Preferably, the inlet channel has at least three bends, with each bend having an angle greater than or equal to 150 degrees. A bend signifies a change in the flow direction of the liquid. Compared to a direct flow path, these bends generate a higher velocity gradient across the channel width, promoting turbulence. Turbulence implies high shear force, effectively reducing solute accumulation on the filter layer surface, maintaining a stable filtration flux, thus delaying membrane clogging and extending membrane pack lifespan. Furthermore, compared to a direct flow path, bends also increase the total length of the channel, improving the filtration efficiency of the membrane pack.

[0009] Preferably, the height of the inlet channel is 0.2-0.8 mm. A suitable inlet channel can ensure effective inlet flow, improve filtration efficiency, and effectively ensure the formation of turbulence.

[0010] Preferably, the liquid-permeable component has a liquid-permeable groove, and the filter layer is disposed in the liquid-permeable groove, which communicates with the liquid-permeable port. The space of the liquid-permeable groove is used to place the filter layer, the sealing gasket, and the liquid inlet component, which helps to ensure the sealing effect of the liquid inlet component and the liquid-permeable component.

[0011] Preferably, the permeate groove is provided with multiple support ribs, and permeate flow channels are formed between adjacent support ribs. The tops of the support ribs contact the filter layer. The tops of the support ribs support the filter layer, preventing the filter layer from adhering to the bottom surface of the permeate element and reducing the impact on the permeate flux. At the same time, the gaps between the support ribs form permeate flow channels, ensuring the filtration effect. The filtered permeate enters the flow channels and then exits from the permeate port on the permeate element.

[0012] Preferably, the edge of the filter layer is provided with a sealing gasket, which is clamped between the liquid inlet and the edge of the filter layer.

[0013] Preferably, the outer shell is integrally formed and covers the outside of the filter assembly, and the outer shell achieves a seal by compressing the liquid inlet and liquid outlet; or, the outer shell includes at least two sub-shells, which, after being installed with the filter assembly, form a compression seal on the liquid inlet and liquid outlet.

[0014] Preferably, at least one of the outer surfaces of the inlet and outlet components is provided with ribs, the height of which increases from one end to the other. The ribs improve the overall strength of the inlet or outlet component, which helps ensure a good seal and the integrity of the filter layer. Furthermore, when the filter assembly is placed inside the housing, the side with the lower rib height is placed first. As the filter assembly is placed to its deepest point, the gap between the ribs and the housing decreases, and the housing applies increasing pressure on the ribs, further clamping the inlet and outlet components to the filter layer, thus ensuring a complete seal of the filter assembly.

[0015] Preferably, at least one of the liquid inlet side and liquid outlet side of the filter layer is provided with a screen. By providing screens on both sides of the filter layer as an alternative to providing ribs on the liquid inlet and liquid outlet components, manufacturing costs can be effectively reduced, filtration efficiency can be improved, maintenance difficulty can be reduced, and the overall filtration system structure design can be made more compact.

[0016] Preferably, the filter layer includes at least one filter membrane, which is any one of cellulose filter membrane, polyethersulfone filter membrane, polytetrafluoroethylene filter membrane, and polyvinylidene fluoride filter membrane.

[0017] The beneficial effects of this utility model are: (1) It adopts a disposable design to avoid the risk of cross-contamination, thereby saving cleaning and sterilization time and reducing maintenance costs; (2) Compared with multi-layer filter layers, the volume of single-layer filter layer is significantly reduced, avoiding material waste and making it more suitable for laboratory and small-scale liquid filters; (3) By setting ribs, the filter components and the outer shell are tightly fitted, ensuring the sealing effect between the liquid inlet and the liquid permeate; (4) The liquid inlet is set with multiple corners in the liquid inlet channel to promote the generation of liquid inlet turbulence, effectively reducing the accumulation of solute on the surface of the filter layer, delaying the clogging of the filter membrane, maintaining a stable filtration flux, and improving the filtration efficiency of the membrane pack. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of a structure according to Embodiment 1 of this utility model;

[0019] Figure 2 This is a schematic diagram of the liquid inlet structure of Embodiment 1 of this utility model;

[0020] Figure 3 This is a schematic diagram of the liquid outlet structure of Embodiment 1 of this utility model;

[0021] Figure 4 This is a top view of the liquid outlet component of Embodiment 1 of this utility model;

[0022] Figure 5 This is a schematic diagram of the outer shell structure of Embodiment 2 of this utility model;

[0023] Figure 6 This is a schematic diagram of the filter assembly structure of Embodiment 2 of this utility model;

[0024] Figure 7 This is a schematic diagram of a structure of embodiment 3 of this utility model;

[0025] Figure 8 This is a schematic diagram of a structure of embodiment 4 of this utility model;

[0026] Figure 9 This is a schematic diagram of the liquid inlet channel in Embodiment 5 of this utility model;

[0027] Figure 10 This is another structural schematic diagram of the liquid inlet channel in Embodiment 5 of this utility model.

[0028] In the diagram: Filter assembly 1, liquid inlet 11, liquid inlet 11a, liquid outlet 11b, liquid inlet channel 11c, liquid permeation component 12, liquid permeation groove 12a, liquid permeation port 12b, support rib 12c, liquid permeation channel 12d, rib 13, outer shell 2, left shell 2a, right shell 2b, half-groove 2c, upper shell 2d, lower shell 2e, filter layer 3, sealing gasket 4, screen 5. Detailed Implementation

[0029] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0030] Example 1

[0031] like Figure 1 In the illustrated embodiment, a disposable filter membrane package includes a housing 2 and a filter assembly 1. The filter assembly 1 includes a liquid inlet 11, a liquid permeate 12, and a filter layer 3. A sealing gasket 4 is provided at the edge of the filter layer 3, clamping the edges of the liquid inlet 11 and the filter layer 3. The liquid inlet 11 and the liquid permeate 12 are sealed together, and the filter layer 3 is positioned between the liquid inlet 11 and the liquid permeate 12. The housing 2 integrally molds and covers the outside of the filter assembly 1, achieving a compression seal on the liquid inlet 11 and the liquid permeate 12. The housing 2 can be made of materials such as PE, PP, PVC, PET, PMMA, PC, and PU. Using completely transparent PC material allows operators to directly observe the flow state of the fluid inside the membrane package, such as liquid distribution, bubble formation, or particle deposition, enabling timely identification of blockages, dry film, or abnormal phenomena. This allows for rapid adjustment of parameters such as pressure and flow rate, reducing the risk of experimental or production failures. The filter layer 3 includes at least one filter membrane, which is any one of cellulose filter membrane, polyethersulfone filter membrane, polytetrafluoroethylene filter membrane and polyvinylidene fluoride filter membrane.

[0032] like Figure 2As shown, the liquid inlet 11 has a flat plate structure and is provided with an inlet 11a and an outlet 11b that communicate with the liquid inlet side of the filter layer 3. Figure 3 As shown, the inlet component 11 has an inlet channel 11c on the side facing the filter layer 3, which is connected to both the inlet port 11a and the outlet port 11b. The inlet channel 11c has three bends, each with an angle of 180 degrees. Compared to a direct flow channel, when the liquid flows to the bends, a higher velocity gradient is generated across the width of the inlet channel 11c. These gradients promote turbulence, which implies high shear force, helping to reduce impurity accumulation on the membrane surface, maintain a stable filtration flux, and thus delay membrane clogging and extend the membrane pack's lifespan. Simultaneously, compared to a direct flow channel, the bends also increase the total length of the inlet channel 11c, improving the membrane pack's filtration efficiency. The height of the inlet channel 11c is 0.2-0.8 mm. The height of the inlet channel 11c must be greater than or equal to 0.2 mm to ensure effective inlet flux and improve filtration efficiency, while the height must be less than or equal to 0.8 mm to effectively ensure the formation of turbulence.

[0033] like Figure 1 , Figure 4 As shown, the liquid permeating element 12 is also a flat plate structure. The liquid permeating element 12 has a liquid permeation port 12b that communicates with the liquid outlet side of the filter layer 3. The liquid permeating element 12 has a liquid permeation groove 12a, in which the filter layer 3 is disposed. The liquid permeation groove 12a communicates with the liquid permeation port 12b. Because the liquid permeating element 12 is concave overall, the liquid permeation groove 12a formed by the concavity is used to place the filter layer 3, the sealing gasket 4, and the liquid inlet element 11, ensuring a sealing effect between the liquid inlet element 11 and the liquid permeating element 12. Multiple support ribs 12c are provided within the liquid permeation groove 12a. The top of the support ribs 12c contacts the filter layer 3, providing support for the filter layer 3 and preventing the filter layer 3 from adhering to the bottom surface of the liquid permeating element 12, thereby ensuring the liquid permeation flow rate. A liquid permeation channel 12d is formed between adjacent support ribs 12c, facilitating the liquid permeation to enter the liquid permeation port 12b along the liquid permeation channel 12d.

[0034] In the actual filtration process, the feed liquid enters from the inlet 11a of the inlet 11 and is distributed to the inlet surface of the filter layer 3 along the inlet flow channel 11c. After tangential filtration by the filter layer 3, it forms the permeate. The unfiltered feed liquid flows out from the outlet 11b. The permeate flows along the permeate flow channel 12d to the permeate outlet 12b and is finally discharged from the membrane.

[0035] Example 2

[0036] The difference between Example 2 and Example 1 is that, as Figure 5As shown, the outer casing 2 includes two sub-casings, a left casing 2a and a right casing 2b, with a space between the left casing 2a and the right casing 2b for installing the filter assembly 1. The left casing 2a and the right casing 2b each have a semi-groove 2c through which the liquid inlet 11a and the liquid outlet 11b extend outwards. Combined with... Figure 6 As shown, at least one of the outer surfaces of the liquid inlet 11 and the liquid permeation 12 is provided with ribs 13. The height of the ribs 13 increases from one end to the other. During the installation of the filter assembly 1 formed by the combination of the liquid inlet 11 and the liquid permeation 12 into the housing 2, the side with the lower height of the ribs 13 is placed into the housing 2 first. As the filter assembly 1 is placed to the deepest point, the gap between it and the housing 2 becomes smaller and smaller. The housing 2 will apply a pressing force to the filter assembly 1. Then, through assembly, welding, bonding or bolting, the left housing 2a and the right housing 2b are combined with the filter assembly 1 into a whole. The filter layer 3 between the liquid inlet 11 and the liquid permeation 12 is completely sealed by the squeezing action of the housing 2.

[0037] Example 3

[0038] The difference between Example 3 and Example 1 is that, as Figure 7 As shown, the outer casing 2 includes two sub-casings, namely an upper casing 2d and a lower casing 2e, with a space between the upper casing 2d and the lower casing 2e for installing the filter assembly 1. The upper casing 2d and the lower casing 2e are assembled with the filter assembly 1 to form a whole through assembly, welding, bonding, or bolting, and provide clamping force to the liquid inlet 11 and the liquid permeation part 12, so that the liquid inlet 11 and the liquid permeation part 12 form a compression seal on the filter layer 3. The sealing gasket 4 has a circular cross-sectional shape, which has excellent pressure distribution characteristics and adaptability.

[0039] Example 4

[0040] The difference between Example 4 and Example 1 is that, as Figure 8 As shown, the filter layer 3 has screens 5 on both the inlet and outlet sides, eliminating the need for an inlet channel on the side of the inlet component 11 facing the filter layer 3, and also eliminating the need for support ribs in the permeate groove 12a. This effectively simplifies the structure of the filtration device. By replacing the inlet channel 11c or permeate channel 12d formed on the traditional inlet component 11 and permeate component 12 with screens 5 on both sides of the filter layer 3, manufacturing costs are effectively reduced, filtration efficiency is improved, and maintenance difficulty is reduced. In addition, this structural design makes the entire filtration system more compact, helping to save space and improve the overall performance of the system. It is suitable for laboratory and small-scale feed liquid filters, as well as applications with high requirements for filter membrane package size.

[0041] Example 5

[0042] The difference between Example 5 and Example 1 is that, as Figure 9 As shown, by designing the shape of the inlet channel 11c, all its turning angles are set to 210 degrees, which is beneficial for promoting the formation of liquid turbulence, thereby generating higher shear force and reducing solute accumulation on the membrane surface. Furthermore, the turning angles of the inlet channel 11c can be set to different angles according to actual filtration requirements, such as... Figure 10 As shown, the turning angles of the liquid inlet channel 11c are set to 210 degrees, 180 degrees and 150 degrees, thereby further extending the length of the liquid inlet channel 11c and improving the filtration efficiency.

[0043] The embodiments of this utility model have been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this utility model. The description of the above embodiments is only for the purpose of helping to understand the method and core ideas of this utility model. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of this utility model. Therefore, the content of this specification should not be construed as a limitation of this utility model.

Claims

1. A disposable filter membrane package, comprising a housing (2) and a filter assembly (1), characterized in that, The filter assembly (1) includes an inlet (11), a permeable (12), and a filter layer (3). The inlet (11) and the permeable (12) are sealed together. The filter layer (3) is clamped and positioned between the inlet (11) and the permeable (12). The inlet (11) is provided with an inlet (11a) and an outlet (11b) that communicate with the inlet side of the filter layer (3). The permeable (12) is provided with a permeable (12b) that communicates with the outlet side of the filter layer (3).

2. The disposable filter membrane pack according to claim 1, characterized in that, The liquid inlet (11) has a liquid inlet channel (11c) on the side facing the filter layer (3), and the liquid inlet channel (11c) is connected to the liquid inlet (11a) and the liquid outlet (11b) respectively.

3. The disposable filter membrane pack according to claim 2, characterized in that, The liquid inlet channel (11c) has at least 3 turns, and the angle of the turns of the liquid inlet channel (11c) is greater than or equal to 150 degrees.

4. A disposable filter membrane pack according to claim 2 or 3, characterized in that, The height of the liquid inlet channel (11c) is 0.2-0.8 mm.

5. A disposable filter membrane pack according to claim 1, characterized in that, The liquid permeable element (12) is provided with a liquid permeable groove (12a), and the filter layer (3) is disposed in the liquid permeable groove (12a). The liquid permeable groove (12a) is connected to the liquid permeable port (12b).

6. A disposable filter membrane pack according to claim 5, characterized in that, The permeable liquid groove (12a) is provided with a plurality of support ribs (12c), and a permeable liquid flow channel (12d) is formed between adjacent support ribs (12c). The top of the support ribs (12c) is in contact with the filter layer (3).

7. A disposable filter membrane pack according to claim 1, characterized in that, The edge of the filter layer (3) is provided with a sealing gasket (4), which is clamped between the liquid inlet (11) and the edge of the filter layer (3).

8. A disposable filter membrane pack according to claim 1, characterized in that, The outer shell (2) is integrally formed and covers the outside of the filter assembly (1). The outer shell (2) presses against the liquid inlet (11) and the liquid permeation part (12) to achieve a seal; or, the outer shell (2) includes at least two sub-shells. After the sub-shells are installed with the filter assembly (1), they form a compression seal against the liquid inlet (11) and the liquid permeation part (12).

9. A disposable filter membrane pack according to claim 1, characterized in that, At least one of the outer surfaces of the liquid inlet (11) and the liquid permeation part (12) is provided with ribs (13), the height of which increases from one end to the other.

10. A disposable filter membrane pack according to claim 1, characterized in that, At least one of the liquid inlet side and liquid outlet side of the filter layer (3) is provided with a screen (5).

11. A disposable filter membrane pack according to claim 1, characterized in that, The filter layer (3) includes at least one filter membrane, which is any one of cellulose filter membrane, polyethersulfone filter membrane, polytetrafluoroethylene filter membrane and polyvinylidene fluoride filter membrane.

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