Medicine intermediate crystallizing and drying equipment for medicine production

Abstract

The utility model discloses medicine intermediate crystallizing and drying equipment for medicine production, which comprises a drying cylinder, a feeding port of the drying cylinder is connected with a conveying cylinder through a feeding pipe, an auger roller is rotatably mounted in the conveying cylinder, a feeding port of the conveying cylinder is connected with a crushing box through a collecting hopper, and the crushing box is connected with a feeding port of the drying cylinder. A pair of smashing rollers rotating reversely is installed in the smashing box, a plurality of heating pipes are evenly distributed on the outer wall of the drying cylinder in the circumferential direction, a rotating rod is rotatably installed in the drying cylinder, and a shifting plate is connected to the outer wall of the rotating rod through a supporting rod. According to the utility model, the material conveying cylinder and the crushing box are arranged in front of the drying cylinder, so that crystal blocks needing to be dried can be crushed firstly, the crystal blocks with smaller particle sizes can be put into the drying cylinder to be dried, the drying uniformity and the drying efficiency can be improved, and the arrangement of the material conveying cylinder changes the feeding route, so that the drying efficiency is improved. And water vapor generated in the drying cylinder in the drying process can be effectively prevented from wetting the subsequently added crystallization material.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical production and processing technology, and in particular to a pharmaceutical intermediate crystallization and drying device for pharmaceutical production. Background Technology

[0002] Pharmaceutical intermediates are actually chemical raw materials or products used in the process of drug synthesis. They are usually precipitated by crystallization, and therefore inevitably contain a small amount of moisture. This moisture needs to be dried before the pharmaceutical intermediates can be processed in subsequent steps.

[0003] Existing drying equipment typically involves directly immersing the crystal blocks into the drying drum. However, due to the large size of the crystal blocks, the heat distribution inside and outside is not uniform during drying, making it difficult for the internal moisture to evaporate, thus affecting the drying efficiency.

[0004] To address these issues, we propose a pharmaceutical intermediate crystallization and drying equipment for drug production. Utility Model Content

[0005] The purpose of this invention is to provide a pharmaceutical intermediate crystallization and drying device for pharmaceutical production, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A pharmaceutical intermediate crystallization and drying device for pharmaceutical production includes a drying cylinder. The feed inlet of the drying cylinder is connected to a conveying cylinder via a feed pipe. An auger roller is rotatably installed inside the conveying cylinder, and a conveying motor is installed on the conveying cylinder. The feed inlet of the conveying cylinder is connected to a crushing box via a collecting hopper, and a pair of counter-rotating crushing rollers are installed inside the crushing box. Several heating tubes are evenly distributed circumferentially on the outer wall of the drying cylinder, and a rotating rod is rotatably installed inside the drying cylinder. A lever is connected to the outer wall of the rotating rod via a support rod, and the lever is in close contact with the inner wall of the drying cylinder. The rotating rod is hollow inside, and an electric heating wire is connected to the inner wall of the rotating rod.

[0008] In a further embodiment, the conveying cylinder is arranged vertically, and the crushing box and the drying cylinder are located on the left and right sides of the conveying cylinder, respectively. The feed inlet of the conveying cylinder is located at the lower end, and the discharge outlet of the conveying cylinder is located at the higher end.

[0009] In a further embodiment, a pair of meshing gears are installed outside the crushing box, and the two gears correspond one-to-one with the two crushing rollers and are coaxially connected. A crushing motor is also installed outside one of the gears.

[0010] In a further embodiment, a protective cover is connected to the crushing box, and the protective cover has a frustum-shaped structure that is narrower at the top and wider at the bottom.

[0011] In a further embodiment, the heating tube is provided with a heat insulation layer.

[0012] In a further embodiment, a bevel gear ring is coaxially fixed to one end of the rotating rod that protrudes from the side wall of the drying cylinder. A bevel gear is meshed with the bevel gear, and a drying motor is installed under the bevel gear.

[0013] In a further embodiment, the drying cylinder is also equipped with a dehumidifier and a dehumidification pipe, and the dehumidification pipe is connected to the inside of the drying cylinder.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] This invention incorporates a feeding cylinder and a crushing box before the drying cylinder to pre-crush the crystalline blocks to be dried, allowing them to be fed into the drying cylinder with smaller particle sizes. This improves the uniformity and efficiency of the drying process. Furthermore, the feeding cylinder alters the feeding route, effectively preventing water vapor generated during the drying process from wetting the subsequently added crystalline material. In addition, the heating tubes and heating wires enable simultaneous heating and drying inside and outside the drying cylinder, further enhancing the drying efficiency. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the crushing box structure of this utility model;

[0018] Figure 3 This is a schematic diagram of the internal cross-sectional structure of the conveying cylinder of this utility model;

[0019] Figure 4 This is a schematic diagram of the internal cross-sectional structure of the drying cylinder of this utility model.

[0020] In the diagram: 1. Drying cylinder; 2. Feed pipe; 3. Conveying cylinder; 4. Screw roller; 5. Conveying motor; 6. Collecting hopper; 7. Crushing box; 8. Crushing roller; 9. Gear; 10. Crushing motor; 11. Protective cover; 12. Rotating rod; 13. Paddle plate; 14. Heating tube; 15. Heat insulation layer; 16. Heating wire; 17. Bevel gear ring; 18. Bevel gear; 19. Drying motor; 20. Dehumidifier; 21. Dehumidification pipe. Detailed Implementation

[0021] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more.

[0022] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figure 1-4 A pharmaceutical intermediate crystallization and drying device for pharmaceutical production includes a drying cylinder 1. The inlet of the drying cylinder 1 is connected to the lower end of a feed pipe 2, and the higher end of the feed pipe 2 is connected to a conveying cylinder 3. An auger roller 4 is rotatably installed inside the conveying cylinder 3, and a conveying motor 5 is installed on the conveying cylinder 3. The output shaft of the conveying motor 5 is connected to the auger roller 4 to drive the auger roller 4 to rotate. The inlet of the conveying cylinder 3 is connected to the lower end of a collecting hopper 6, and the higher end of the collecting hopper 6 is connected to a crushing box 7. A pair of counter-rotating crushing rollers 8 are installed inside the crushing box 7. Blocky crystals are first fed between the crushing rollers 8, and the crushing rollers 8 rotate to crush them. The crushed material enters the conveying cylinder 3 through the collecting hopper 6, is transported to the feed pipe 2 under the rotation of the auger roller 4, and finally enters the drying cylinder 1 for drying. The smaller particle size fed into the drying cylinder 1 facilitates the improvement of drying uniformity and drying efficiency.

[0025] Furthermore, the conveying cylinder 3 is arranged vertically along its axis, and the crushing box 7 and the drying cylinder 1 are located on the left and right sides of the conveying cylinder 3, respectively. The inlet of the conveying cylinder 3 is located at the lower end, and the outlet of the conveying cylinder 3 is located at the higher end. The drying cylinder 1 is arranged horizontally along its axis. The crushing box 7, the conveying cylinder 3, and the drying cylinder 1 are arranged on a horizontal line, thereby changing the traditional direct downward feeding direction and causing the material to change its path when being fed, thus avoiding direct contact with the water vapor generated during drying when the material is fed, thereby reducing the adhesion of crushed material and conveying material.

[0026] To facilitate crushing, a pair of meshing gears 9 are installed on the outside of the crushing box 7. The two gears 9 correspond one-to-one with the two crushing rollers 8 and are coaxially connected. A crushing motor 10 is also installed on one of the gears 9. The main body of the crushing motor 10 is supported by a bracket, which is fixedly installed on the outer wall of the crushing box 7. The crushing motor 10 drives the two crushing boxes 7 to rotate towards each other, thereby facilitating crushing and crystallization. Specifically, a protective cover 11 can also be connected to the crushing box 7. The protective cover 11 has a truncated pyramidal structure that is narrow at the top and wide at the bottom, which can reduce the material splashing outward during crushing.

[0027] To further improve drying efficiency, several heating tubes 14 are evenly distributed circumferentially on the outer wall of the drying cylinder 1. Each heating tube 14 is covered with a heat insulation layer 15 to reduce heat loss. A rotating rod 12 is rotatably mounted inside the drying cylinder 1. A lever 13 is connected to the outer wall of the rotating rod 12 via a support rod, and the lever 13 is in close contact with the inner wall of the drying cylinder 1 to facilitate turning over the crushed material and ensuring even heating. Furthermore, the rotating rod 12 is hollow inside, and an electric heating wire 16 is connected to its inner wall. This allows the heating tubes 14 to heat the inside of the drying cylinder 1 through contact with it, while the electric heating wire 16, in contact with the rotating rod 12, heats the space between the rotating rod 12 and the drying cylinder 1, achieving simultaneous internal and external heating and drying for higher efficiency. In addition, a dehumidifier 20 and a dehumidification pipe 21 are installed on the drying cylinder 1, and the dehumidification pipe 21 is connected to the inside of the drying cylinder 1 to extract hot and humid air in a timely manner, preventing the dried material from becoming damp.

[0028] Considering that the heating wire 16 is installed inside the rotating rod 12, in order to facilitate the wiring of the rotating rod 12, a bevel gear ring 17 is coaxially fixed to one end of the rotating rod 12 that protrudes from the side wall of the drying cylinder 1. The bevel gear ring 17 is meshed with a bevel gear 18, and a drying motor 19 is installed under the bevel gear 18. The main body of the drying motor 19 is fixed to the side wall of the drying cylinder 1, so that while driving the rotating rod 12 to rotate, it does not affect the wiring of the rotating rod 12.

[0029] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0030] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A pharmaceutical intermediate crystallization and drying device for pharmaceutical production, comprising a drying cylinder (1), characterized in that: The feed inlet of the drying cylinder (1) is connected to the conveying cylinder (3) through the feed pipe (2). The conveying cylinder (3) is rotatably installed with an auger roller (4) and a conveying motor (5) is installed on the conveying cylinder (3). The feed inlet of the conveying cylinder (3) is connected to the crushing box (7) through the collecting hopper (6). A pair of counter-rotating crushing rollers (8) are installed in the crushing box (7). Several heating tubes (14) are evenly distributed along the circumference on the outer wall of the drying cylinder (1). A rotating rod (12) is rotatably installed inside the drying cylinder (1). A lever (13) is connected to the outer wall of the rotating rod (12) through a support rod. The lever (13) is in close contact with the inner wall of the drying cylinder (1). The rotating rod (12) is hollow inside. An electric heating wire (16) is connected to the inner wall of the rotating rod (12).

2. The pharmaceutical intermediate crystallization and drying equipment for pharmaceutical production according to claim 1, characterized in that: The conveying cylinder (3) is arranged vertically, and the crushing box (7) and the drying cylinder (1) are located on the left and right sides of the conveying cylinder (3). The feed inlet of the conveying cylinder (3) is located at the lower end, and the discharge outlet of the conveying cylinder (3) is located at the higher end.

3. The pharmaceutical intermediate crystallization and drying equipment for pharmaceutical production according to claim 1, characterized in that: A pair of meshing gears (9) are installed outside the crushing box (7), and the two gears (9) correspond one-to-one with the two crushing rollers (8) and are coaxially connected. A crushing motor (10) is also installed outside one of the gears (9).

4. The pharmaceutical intermediate crystallization and drying equipment for pharmaceutical production according to claim 1, characterized in that: The crushing box (7) is connected to a protective cover (11), and the protective cover (11) has a truncated pyramidal structure that is narrow at the top and wide at the bottom.

5. The pharmaceutical intermediate crystallization and drying equipment for pharmaceutical production according to claim 1, characterized in that: The heating tube (14) is provided with a heat insulation layer (15).

6. The pharmaceutical intermediate crystallization and drying equipment for pharmaceutical production according to claim 1, characterized in that: The rotating rod (12) is coaxially fixed to one end of the side wall of the drying cylinder (1). A bevel gear (17) is meshed with the bevel gear (18) below the bevel gear (18), and a drying motor (19) is installed below the bevel gear (18).

7. The pharmaceutical intermediate crystallization and drying equipment for pharmaceutical production according to claim 1, characterized in that: The drying cylinder (1) is also equipped with a dehumidifier (20) and a dehumidification pipe (21), and the dehumidification pipe (21) is connected to the inside of the drying cylinder (1).

Images