Mobile phase bottle for liquid chromatograph as well as forming mold and mobile phase loading structure of mobile phase bottle

Abstract

The utility model discloses a mobile phase bottle for a liquid chromatograph as well as a forming mold and a mobile phase loading structure of the mobile phase bottle. The mobile phase bottle is placed above the liquid chromatograph, and at the moment, a certain height difference exists between the liquid level of the mobile phase and the inlet of the liquid phase pump, so that power for natural flowing is formed, and the liquid phase pump can suck liquid smoothly. The mobile phase bottle comprises a bottle body and a mobile phase containing cavity formed in the bottle body. The bottom of the mobile phase containing cavity is of an inverted-cone-shaped structure. The structure of the mobile phase bottle is optimized, so that the mobile phase at the bottom of the bottle is gathered at the conical part, the effect of fully sucking the mobile phase in the bottle is achieved, and the problems that when a traditional liquid chromatograph works, the liquid level in the bottle cannot submerge a liquid sucking opening every time when the mobile phase is used up to be about 1 / 10, the mobile phase cannot be sucked out, and the liquid sucking opening cannot be covered are solved. And the gas enters a pipeline, so that the work of the liquid chromatograph is influenced.

Description

Technical Field

[0001] This utility model relates to the field of liquid chromatograph accessories, and in particular to mobile phase bottles for liquid chromatographs, a molding die for manufacturing the mobile phase bottle, and a mobile phase loading structure having the mobile phase bottle. Background Technology

[0002] Liquid chromatography (LC) uses liquid chromatography separation and analysis technology to detect substances contained in analytes. It uses liquids such as acetonitrile-water solution, acetonitrile-acetic acid solution, methanol-water solution, and acetonitrile-phosphoric acid solution as mobile phases, and paper, thin plates, and packed beds as stationary phases. During chromatography, the mobile phase carries the analyte across the stationary phase. The mobile phase is contained in a mobile phase bottle, which is placed above the LC instrument so that there is a certain height difference between the liquid surface of the mobile phase and the inlet of the liquid pump, thereby creating a natural flow force to facilitate smooth liquid aspiration by the liquid pump during chromatographic analysis.

[0003] When a traditional liquid chromatograph is working, when about 1 / 10 of the mobile phase remains, the liquid level in the mobile phase bottle will no longer cover the suction port. At this point, the mobile phase cannot be suctioned out, and gas enters the pipeline, affecting the operation of the liquid chromatograph. At the same time, the mobile phase in the mobile phase bottle cannot be fully utilized. Utility Model Content

[0004] In view of the shortcomings of the prior art described above, the purpose of this utility model is to provide a mobile phase bottle for liquid chromatography and its molding die and mobile phase loading structure to achieve full absorption of the mobile phase inside the bottle.

[0005] A mobile phase bottle for a liquid chromatograph, which is placed above the liquid chromatograph; the mobile phase bottle includes:

[0006] The bottle body; and

[0007] A flow phase containing cavity formed within the bottle body;

[0008] The bottom of the fluid phase container has an inverted conical shape.

[0009] As a further improvement to the above solution, the bottle body is made of high borosilicate glass, and the capacity of the mobile phase container is ~ml.

[0010] A mobile phase loading structure, comprising:

[0011] The bottle body is the mobile phase bottle for the liquid chromatograph described above;

[0012] The bottle cap is screwed onto the bottle opening;

[0013] Support for supporting the bottle body;

[0014] A glass tube fixed vertically to the bottle cap, located inside the bottle;

[0015] A liquid-drawing tube, which is mounted on the bottle cap, passes through the glass tube; and

[0016] A filter head, fixed to the liquid extraction tube, is located below the glass tube.

[0017] As a further improvement to the above solution, the bottle cap is made of plastic, and a channel for the liquid extraction tube is provided in the center of the bottle cap.

[0018] As a further improvement to the above solution, a placement cavity is provided through the support, and the bottle body is detachably installed in the support through the placement cavity.

[0019] As a further improvement to the above solution, the filter head is installed at the inlet end of the liquid extraction pipe, and the outlet end of the liquid extraction pipe is connected to the inlet of the liquid phase pump.

[0020] A molding die includes two mold bodies; the molding die further includes:

[0021] Cavities formed on the corresponding mold body; and

[0022] An air inlet that connects to the mold cavity;

[0023] The cavity has a V-shaped cross-section on the side facing away from the air inlet.

[0024] As a further improvement to the above scheme, four fixing columns are vertically welded on one of the mold bodies, and positioning holes corresponding to the fixing columns are opened on the remaining mold body.

[0025] As a further improvement to the above scheme, four fixing columns are evenly distributed around the corresponding cavity.

[0026] As a further improvement to the above scheme, the molding die is used to manufacture the mobile phase bottle for the liquid chromatograph.

[0027] Compared with the prior art, the beneficial effects of this utility model are: the structure of the mobile phase bottle has been optimized, so that the mobile phase at the bottom of the bottle gathers in the conical part, thereby achieving the effect of fully absorbing the mobile phase in the bottle. This solves the problem that when the mobile phase is used up to about 1 / 10, the liquid level in the bottle cannot cover the suction port, resulting in the mobile phase not being able to be sucked out and gas entering the pipeline, which affects the operation of the liquid chromatograph. Attached Figure Description

[0028] Figure 1 The diagram shown is a schematic of a mobile phase bottle for a liquid chromatograph provided in Embodiment 1 of this utility model.

[0029] Figure 2 The diagram shown is a schematic diagram of a mobile phase loading structure provided in Embodiment 2 of this utility model.

[0030] Figure 3 The diagram shown is a schematic diagram of a molding die provided in Embodiment 3 of this utility model.

[0031] Explanation of main component symbols

[0032] 1. Bottle body; 2. Mobile phase container cavity; 3. Bottle cap; 4. Support; 5. Liquid extraction tube; 6. Filter head; 7. Glass tube; 8. Mold body; 9. Cavity; 10. Air blowing port.

[0033] The above description of the main component symbols, together with the accompanying drawings and specific embodiments, provides a further detailed explanation of this utility model. Detailed Implementation

[0034] The present invention will now be described in detail with reference to the accompanying drawings. Example 1

[0035] Please see Figure 1 This embodiment provides a mobile phase bottle for a liquid chromatograph, which is placed above the liquid chromatograph. When the mobile phase bottle is placed above the liquid chromatograph, there is a certain height difference between the liquid surface of the mobile phase and the inlet of the liquid pump, which creates a natural flow force and is more conducive to the smooth aspiration of the liquid by the liquid pump.

[0036] The mobile phase vial includes a vial body 1 and a mobile phase holding chamber 2 formed within the vial body 1. The vial body 1 is made of high borosilicate glass, and the capacity of the mobile phase holding chamber 2 is 1000 ml. The bottom of the mobile phase holding chamber 2 has an inverted conical shape.

[0037] In this embodiment, the structure of the mobile phase bottle has been optimized so that the mobile phase at the bottom of the bottle converges in the conical part, thereby achieving the effect of fully absorbing the mobile phase in the bottle. This solves the problem that when the mobile phase is used up to about 1 / 10, the liquid level in the bottle cannot cover the suction port, resulting in the mobile phase not being able to be sucked out, gas entering the pipeline, and affecting the operation of the liquid chromatograph. Example 2

[0038] Please see Figure 2 This embodiment provides a mobile phase loading structure, which includes a bottle body, a bottle cap 3 screwed onto the bottle mouth, a support 4 for supporting the bottle body, a liquid extraction tube 5 movably mounted on the bottle cap 3, a filter head 6 fixed to the liquid extraction tube 5, and a glass tube 7 vertically fixed to the bottle cap 3.

[0039] In this embodiment, the mobile phase bottle is the same as that in Embodiment 1. The mobile phase inside the bottle converges in the conical section to ensure sufficient absorption during chromatographic analysis. A placement cavity is provided through the support 4, through which the bottle can be detachably mounted. Considering the bottle structure, this embodiment uses the support 4 for support, allowing the bottle to be placed stably.

[0040] The bottle cap 3 is made of plastic, and a channel for the passage of the extraction tube 5 is provided in the center of the bottle cap 3. The extraction tube 5 passes through the glass tube 7, and the filter head 6 is located below the glass tube 7. The filter head 6 is installed at the inlet end of the extraction tube 5, and the outlet end of the extraction tube 5 is connected to the inlet of the liquid phase pump. In this embodiment, the mobile phase loading structure uses a liquid phase pump (not shown) to draw the mobile phase. The specific process is as follows: the liquid phase pump is started, and the mobile phase is filtered by the filter head 6 and then drawn into the extraction tube 5 and directionally delivered to the liquid chromatograph for chromatographic analysis.

[0041] The glass tube 7 is located inside the bottle, and is fixed to the bottle cap 3 using an adhesive material such as epoxy resin. In this embodiment, the glass tube 7 serves two purposes: firstly, it acts as a guide, allowing the liquid extraction tube 5 to be inserted into the bottle along its center position; secondly, it acts as a limiting element, ensuring that the filter head 6 is always located at the center of the conical section, thus facilitating the full utilization of the mobile phase inside the bottle. Example 3

[0042] This embodiment provides a molding die for manufacturing a mobile phase vial for a liquid chromatograph, as described in Embodiment 1. The molding die includes two mold bodies 8, cavities 9 formed on corresponding mold bodies 8, and air inlets 10 communicating with the cavities 9. The cavity 9, facing away from the air inlet 10, has a V-shaped cross-section. Four fixing posts are vertically welded to one of the mold bodies 8, and positioning holes corresponding to the fixing posts are formed on the remaining mold body 8. The four fixing posts are evenly distributed around the perimeter of the corresponding cavity 9. In this embodiment, the fixing posts and positioning holes cooperate to provide guidance for the mold closing of the two mold bodies 8, improving the fit of the mold during closing.

[0043] The molding die of this embodiment is used as follows: the glass blank obtained by the glass droplet after one treatment is placed in the cavity 9, the mold is closed, and air is blown in by the air blowing port 10. Under the shaping of the cavity 9, a flow phase bottle with a conical part is obtained.

[0044] The naming of each component is based on its function as described in the specification, and is not limited to the specific terms used in this utility model. Those skilled in the art may also choose other terms to describe the names of the components of this utility model.

Claims

1. A mobile phase bottle for a liquid chromatograph, which is placed above the liquid chromatograph; Its features are, The mobile phase bottle includes: Bottle body (1); and A flow phase holding cavity (2) is formed inside the bottle body (1); The bottom of the fluid phase container (2) has an inverted cone shape.

2. The mobile phase bottle for liquid chromatograph according to claim 1, characterized in that, The bottle body (1) is made of high borosilicate glass, and the capacity of the mobile phase container (2) is 100~1000ml.

3. A mobile phase loading structure, characterized in that, include: The bottle body is a mobile phase bottle for liquid chromatograph as described in any one of claims 1 to 2; The bottle cap (3) is screwed onto the bottle opening; Support (4) for supporting the bottle body; A glass tube (7) is vertically fixed to the bottle cap (3) and is located inside the bottle; The liquid extraction tube (5) is mounted on the bottle cap (3) and passes through the glass tube (7); and A filter head (6) is fixed to the liquid extraction tube (5) and is located below the glass tube (7).

4. The mobile phase loading structure according to claim 3, characterized in that, The bottle cap (3) is made of plastic, and a channel for the liquid extraction tube (5) is provided in the center of the bottle cap (3).

5. The mobile phase loading structure according to claim 4, characterized in that, The support (4) has a through-hole for placing the bottle body, which can be detachably installed in the support (4) through the placing hole.

6. The mobile phase loading structure according to claim 3, characterized in that, The filter head (6) is installed at the inlet end of the liquid extraction pipe (5), and the outlet end of the liquid extraction pipe (5) is connected to the inlet of the liquid phase pump.

7. A molding die comprising two mold bodies (8); Its features are, The molding die also includes: Cavities (9) formed on the corresponding mold body (8); and An air inlet (10) that is connected to the cavity (9); The cavity (9) is located on the side facing away from the air inlet (10), and its cross-section is V-shaped.

8. The molding die according to claim 7, characterized in that, Four fixing columns are vertically welded on one of the molds (8), and positioning holes corresponding to the fixing columns are opened on the remaining mold (8); Four fixed columns are evenly distributed around the corresponding cavity (9).

9. The molding die according to claim 8, characterized in that, The molding die is used to manufacture the mobile phase bottle for liquid chromatograph as described in any one of claims 1 to 2.

Images