Novel exfoliated cell DNA (deoxyribonucleic acid) collecting device
By using a flat nylon fiber collection head and a polypropylene collection rod, the problems of cell dispersion caused by traditional cotton swab heads and interference from natural inhibitors were solved, thus improving the DNA detection rate and PCR accuracy.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- JIAXIANG COUNTY PUBLIC SECURITY BUREAU
- Filing Date
- 2025-05-23
- Publication Date
- 2026-05-12
AI Technical Summary
In existing technologies, traditional cotton swabs have cylindrical or conical tips and use a two-step collection method, which leads to the dispersion of exfoliated cells, reducing the detection rate. Furthermore, components in natural cotton fibers interfere with DNA/RNA extraction and amplification, affecting the sensitivity and accuracy of PCR.
It uses a flat, rectangular nylon fiber collection head to collect detached cells in two steps. The high absorbency of nylon fiber improves the capture rate, and the collection rod made of polypropylene provides a stable grip to prevent cell dispersion.
It improved the detection rate of exfoliated cells, reduced cell dispersion, enhanced the accuracy of DNA extraction and PCR amplification, and reduced interference from natural inhibitors.
Smart Images
Figure CN224227061U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to criminal investigation evidence collection equipment technical field, concretely is a new type of exfoliation cell DNA collection device. BACKGROUND
[0002] The current case scene investigation adopts the cotton swab head to collect the exfoliation cell DNA, and the cotton swab head is mostly cylindrical or conical, and the collection method mostly adopts two-step method, that is, first, the cotton swab head is wetted by liquid, then the exfoliation cell carrier surface is wiped, and second, the carrier surface is wiped by dry cotton swab. Two-step method can fully extract the exfoliation cell on the carrier, and reduce loss. But the exfoliation cell on the carrier is distributed in multiple cotton swabs, which reduces the amount of exfoliation cell on a single cotton swab, reduces the enrichment of exfoliation cell, affects the extraction and PCR amplification of DNA in the next step, and reduces the detection rate. In addition, the head of the traditional exfoliation cell extraction cotton swab uses natural cotton fiber, and the natural cotton fiber contains natural components such as polysaccharide, phenolic compound and lignin. These substances can interfere with the extraction and amplification of DNA / RNA, and reduce the sensitivity and accuracy of PCR. In addition, the cotton fiber can also adsorb nucleic acid, resulting in sample loss. Therefore, the traditional extraction cotton swab and extraction method cannot meet the requirements of modern scene investigation and DNA laboratory test. CONTENT OF THE UTILITY MODEL
[0003] In view of the problems existing in the prior art, the utility model discloses a new type of exfoliation cell DNA collection device, which adopts the technical scheme that a collection rod and a collection head connected therewith are included.
[0004] The collection rod includes a rod body, a connecting groove and a breaking groove, the connecting groove and the breaking groove are arranged on the rod body, the depth of the breaking groove is greater than that of the connecting groove, and one end of the rod body is inserted into the inside of the collection head and fixedly connected in the collection head.
[0005] The collection head includes a collection part, a connecting part and a convex part, the collection part is in the shape of a flat cuboid, a connecting part is arranged on the middle part of the side surface of one end of the collection part, the connecting part is sleeved on the outside of one end of the collection rod, a convex part is arranged on the inside surface of the connecting part away from one end of the collection part, the convex part is fixedly connected in the connecting groove, and the material of the collection head is nylon fiber.
[0006] As a preferred technical scheme of the utility model, the material of the rod body is polypropylene.
[0007] As a preferred technical scheme of the utility model, the side surface of the end of the collection rod away from the collection head is provided with outward convex anti-skid lines.
[0008] The utility model discloses a beneficial effect: the utility model discloses a flat cuboid is changed to the collection head, can spray wet one side of collection department cuboid when using, wipe the surface of the exfoliative cell carrier, then use dry the other side to wipe the carrier again, like this has overcome the shortcoming that the trace exfoliative cell of traditional " two -step method " is distributed in a plurality of cotton swab, causes the exfoliative cell dispersion, has improved the detection rate. The material of collection head is nylon fibre, and the nylon fibre is a kind of synthetic material, and the price is low, does not contain natural inhibitor, has high adsorption to exfoliative cell, improves the capture rate to exfoliative cell, has high release efficiency when cleaving. BRIEF DESCRIPTION OF DRAWINGS
[0009] Fig. 1 It is whole structure schematic diagram of the utility model;
[0010] Fig. 2 It is collection rod and collection head structure schematic diagram of the utility model;
[0011] Fig. 3 It is cross section structure schematic diagram of the utility model.
[0012] In the drawing: 1 collection rod, 101 rod body, 102 connecting groove, 103 breaking groove, 2 collection head, 201 collection part, 202 connecting part, 203 convex part, 3 anti -slip line. DETAILED DESCRIPTION
[0013] Example 1
[0014] As Figs. 1 to 3 Shown, the utility model discloses a novel exfoliative cell DNA collection device, adopts the technical scheme, including collection rod 1 and with the collection head 2 of connection;
[0015] Collection rod 1 includes rod body 101, connecting groove 102 and breaking groove 103, is set with connecting groove 102 and breaking groove 103 on rod body 101, and the depth of breaking groove 103 is greater than the depth of connecting groove 102, and one end of rod body 1 is inserted in the inside of collection head 2 and is fixedly connected in collection head 2, and the material of rod body 101 is polypropylene, and the side of the end of collection rod 1 away from collection head 2 is provided with the anti -slip line that protrudes outward;
[0016] The collection head 2 includes a collection part 201, a connecting part 202 and a protruding part 203, the collection part 201 is in the shape of a flat cuboid, the middle part of the one end side surface of the collection part 201 is provided with the connecting part 202, the connecting part 202 is sleeved on the outside of the one end of the collection rod 101, the inner side surface of the connecting part 202 away from the one end of the collection part 201 is provided with the protruding part 203, the protruding part 203 is fixedly connected in the connecting groove 102, and the material of the collection head 2 is nylon fiber. The working principle of the utility model: when collecting the DNA of the exfoliated cells, the operator holds the collection rod 1, stably holds by the anti-skid lines 3, sprays the one side of the collection part 201 of the collection head 2 with the special cell collection liquid, wipes the surface of the exfoliated cell carrier with the sprayed side, the exfoliated cells are adsorbed on the collection part 201 due to the high adsorption of the nylon fiber. Without replacing the tool, the other dry side of the collection part 201 is used to wipe the surface of the carrier again, and the possible missed exfoliated cells are further collected. After the collection is completed, if it is necessary to preserve or follow-up experiment operation for the collected sample, the collection rod 1 can be broken at the broken groove 103 according to actual needs, the collection head 2 with the sample is properly preserved or transferred to the corresponding experimental equipment to carry out the subsequent DNA extraction, amplification and detection and the like.
[0017] The components not described in detail herein are prior art.
[0018] Although the specific embodiments of the utility model have been described in detail above, the utility model is not limited to the above-mentioned embodiments, and various changes can be made within the knowledge range possessed by those skilled in the art without departing from the purpose of the utility model, and the modifications or deformations without creative labor are still within the protection range of the utility model.
Claims
1. A novel exfoliated cell DNA collection device, characterized in that, It includes a sampling rod (1) and a sampling head (2) connected to it; The collecting rod (1) includes a rod body (101), a connecting groove (102) and a break groove (103). The connecting groove (102) and the break groove (103) are provided on the rod body (101). The depth of the break groove (103) is greater than the depth of the connecting groove (102). One end of the rod body (1) is inserted into the inside of the collecting head (2) and fixedly connected inside the collecting head (2). The collection head (2) includes a collection part (201), a connecting part (202), and a protrusion (203). The collection part (201) is a flat cuboid. The connecting part (202) is provided in the middle of one side of the collection part (201). The connecting part (202) is sleeved on the outside of one end of the collection rod (1). The protrusion (203) is provided on the inner side of the connecting part (202) away from the collection part (201). The protrusion (203) is fixedly connected in the connecting groove (102). The material of the collection head (2) is nylon fiber.
2. The novel exfoliated cell DNA collection device according to claim 1, characterized in that: The rod (101) is made of polypropylene.
3. The novel exfoliated cell DNA collection device according to claim 1, characterized in that: The side of the sampling rod (1) away from the sampling head (2) has outwardly protruding anti-slip texture (3).