Hematopoietic stem cell liquid nitrogen transfer tank
By designing the outlet, storage tank, telescopic rod, spring, and vent pipe structure of the hematopoietic stem cell liquid nitrogen transfer vessel, the problem of increased pressure caused by frequent opening of the vessel lid during use was solved, thus achieving internal pressure stability and safety.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- WUHAN VISION BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-01-07
- Publication Date
- 2026-05-29
AI Technical Summary
When the lid of a liquid nitrogen transfer tank is frequently opened and closed during use, the evaporation of liquid nitrogen causes a sharp increase in internal pressure, increasing the risk of damage.
A liquid nitrogen transfer container for hematopoietic stem cells was designed. Through the combination of an outlet, a storage tank, a telescopic rod, a spring, an exhaust pipe, and a storage bag, the gas channel is automatically adjusted by the cooperation of the spring and the telescopic rod. The evaporated liquid nitrogen gas enters the storage bag through the exhaust pipe, reducing the internal pressure of the container.
It effectively reduces pressure fluctuations inside the liquid nitrogen transfer tank, lowers usage risks, and prevents nitrogen from posing a threat to operators and the environment.
Smart Images

Figure CN224291111U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to a liquid nitrogen transfer vessel for stem cells, specifically a liquid nitrogen transfer vessel for hematopoietic stem cells, and belongs to the technical field of liquid nitrogen transfer vessels. Background Technology
[0002] The main function of liquid nitrogen tanks is to cryogenically store biological samples, especially for the long-term preservation of biological samples and cells. The liquid nitrogen inside the tank has an extremely low temperature, reaching -196 degrees Celsius, which can effectively prevent cell metabolism and degeneration. Hematopoietic stem cells are cells with important medical applications and can be used to treat various blood diseases and immune system diseases. In order to preserve and transport hematopoietic stem cells for a long time, ultra-low temperature freezing is required using liquid nitrogen transfer tanks.
[0003] However, during the use of liquid nitrogen transfer containers, the lid needs to be opened and closed frequently to remove or add hematopoietic stem cells. Each time the lid is opened, some liquid nitrogen evaporates and expands. If this gas cannot be effectively discharged, it may cause the internal pressure of the container to increase sharply in a short period of time, increasing the risk of use. To address this issue, we have provided a hematopoietic stem cell liquid nitrogen transfer container to solve the above problems. Utility Model Content
[0004] To address the aforementioned problems, this utility model provides a liquid nitrogen transfer container for hematopoietic stem cells, and the specific technical solution is as follows:
[0005] A liquid nitrogen transfer container for hematopoietic stem cells includes a container body. An outlet is fixedly connected to the bottom surface of the container body. A spiral tube is threadedly connected to the outer surface of the outlet. A storage tank is fixedly connected to the outer surface of the spiral tube. A movable plate is slidably connected to the inner wall of the spiral tube. A telescopic rod is connected to the outer surface of the movable plate. A circular plate is connected to one end of the telescopic rod. A spring is sleeved on the outside of the telescopic rod. One end of the spring is connected to the bottom surface of the movable plate, and the other end of the spring is connected to the upper surface of the circular plate. The outer surface of the circular plate is connected to the inner wall of the storage tank. An outlet pipe is fixedly connected to the outer surface of the storage tank.
[0006] Preferably, a limiting plate is connected to the outer surface of the movable plate, a limiting groove is formed on the inner wall of the spiral tube, and the outer surface of the limiting plate is slidably connected to the inner wall of the limiting groove.
[0007] Preferably, a rubber stopper is slidably connected to the inner wall of the air outlet pipe, and a pull rod is connected to the outer surface of the rubber stopper.
[0008] Preferably, the upper surface of the circular plate has through holes, which are evenly distributed on the upper surface of the circular plate.
[0009] Preferably, a storage bag is slidably connected to the outer surface of the air outlet pipe, and a drawstring is provided on the outer surface of the storage bag.
[0010] Preferably, a support rod is connected to the bottom surface of the tank, a rubber pad is connected to the bottom end of the support rod, and a bracket is connected to the outer surface of the tank.
[0011] Preferably, there are four storage bags, which are evenly distributed on the outer surface of the storage tank.
[0012] Compared with the prior art, the present invention has the following beneficial effects:
[0013] 1. This hematopoietic stem cell liquid nitrogen transfer container works by coordinating an outlet, storage tank, telescopic rod, spring, vent pipe, and storage bag. When the liquid nitrogen evaporates, the pressure inside the container increases, causing the moving plate to move downwards. This compresses the spring, shortens the telescopic rod, and the moving plate moves away from the spiral tube. Gas enters the storage tank and then flows through the vent pipe into the storage bag for nitrogen storage. This reduces the internal pressure of the container and solves the problem of frequent opening and closing of the container lid to retrieve or add hematopoietic stem cells. Each time the lid is opened, some liquid nitrogen evaporates and expands. If this gas cannot be effectively discharged, it may cause a rapid increase in internal pressure within the container, increasing the risk of infection.
[0014] 2. This hematopoietic stem cell liquid nitrogen transfer container works by connecting a rubber stopper, a pull rod, a circular plate, a through hole, an exhaust pipe, and a storage bag. When using the device, the rubber stopper is removed from the inside of the exhaust pipe, and the gas in the storage container will flow into the storage bag through the exhaust pipe. The opening of the storage bag is then sealed with a drawstring, and the nitrogen in the storage bag is transported to a suitable location. This prevents the exhaust gas from posing a threat to operators and the environment. Attached Figure Description
[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0016] Figure 2 This is a partial structural cross-sectional view of the present invention;
[0017] Figure 3 This is a schematic diagram showing the positional relationship between the storage bag and the drawstring of this utility model;
[0018] Figure 4 For the present utility model Figure 1 Enlarged view of the structure of section A in the middle;
[0019] Figure 5 For the present utility model Figure 1 Enlarged view of the structure of section B in the middle.
[0020] Attached diagram descriptions: 1. Tank body; 2. Outlet port; 3. Screw tube; 4. Storage tank; 5. Moving plate; 6. Telescopic rod; 7. Circular plate; 8. Spring; 9. Vent pipe; 10. Limiting plate; 11. Limiting groove; 12. Rubber stopper; 13. Pull rod; 14. Through hole; 15. Storage bag; 16. Tie rope; 17. Support rod; 18. Rubber pad; 19. Bracket. Detailed Implementation
[0021] The present invention will now be further described with reference to the accompanying drawings.
[0022] Please see Figure 1-5 As shown, a liquid nitrogen transfer container for hematopoietic stem cells includes a container body 1. A support rod 17 is connected to the bottom surface of the container body 1, and a rubber pad 18 is connected to the bottom end of the support rod 17. A bracket 19 is connected to the outer surface of the container body 1. There are four support rods 17, which are evenly distributed on the bottom surface of the container body 1. The support rods 17 can fix the container body 1. The rubber pad 18 can increase the friction between the support rod 17 and the ground, making the container body 1 more stable. The rubber pad 18 is made of natural rubber, which has good comprehensive mechanical properties, cold resistance, high resilience and wear resistance.
[0023] The bottom surface of the tank 1 is fixedly connected to an outlet 2. A screw tube 3 is threadedly connected to the outer surface of the outlet 2. A storage tank 4 is fixedly connected to the outer surface of the screw tube 3. The screw tube 3 and the outlet 2 are connected by threads, which facilitates the installation and disassembly of the storage tank 4 and makes it convenient to use the storage tank 4. A movable plate 5 is slidably connected to the inner wall of the screw tube 3. A limit plate 10 is connected to the outer surface of the movable plate 5. A limit groove 11 is opened on the inner wall of the screw tube 3. The outer surface of the limit plate 10 is slidably connected to the inner wall of the limit groove 11. There are four limit plates 10, which are evenly distributed on the outer surface of the movable plate 5. The limit plates 10 can limit the movement of the movable plate 5, so that the movable plate 5 can move horizontally up and down. When the movable plate 5 is disengaged from the screw tube 3, the gas release channel will open. When the movable plate 5 is not disengaged from the screw tube 3, the gas release channel will close.
[0024] A telescopic rod 6 is connected to the outer surface of the movable plate 5. One end of the telescopic rod 6 is connected to a circular plate 7. A through hole 14 is opened on the upper surface of the circular plate 7. The through holes 14 are evenly distributed on the upper surface of the circular plate 7. The through holes 14 allow nitrogen gas to flow freely inside the storage tank 4. A spring 8 is sleeved on the outside of the telescopic rod 6. The purpose of setting the telescopic rod 6 is to keep the spring 8 in a vertical state. The telescopic rod 6 can only extend and shorten under the pull or compression of external force. The telescopic rod 6 cannot extend and compress automatically.
[0025] One end of the spring 8 is connected to the bottom surface of the movable plate 5, and the other end of the spring 8 is connected to the upper surface of the circular plate 7. The outer surface of the circular plate 7 is connected to the inner wall of the storage tank 4. The outer surface of the storage tank 4 is fixedly connected to the air outlet pipe 9. The outer surface of the air outlet pipe 9 is slidably connected to the storage bag 15. The outer surface of the storage bag 15 is provided with a drawstring 16. The storage bag 15 has a certain degree of elasticity. When the pressure inside the storage bag 15 increases, the volume of the storage bag 15 will increase. When the pressure inside the storage bag 15 decreases, the volume of the storage bag 15 will decrease. Its material is rubber, and its working principle is similar to that of a balloon.
[0026] A rubber stopper 12 is slidably connected to the inner wall of the vent pipe 9. A pull rod 13 is connected to the outer surface of the rubber stopper 12. Pulling the pull rod 13 can remove the rubber stopper 12 from the inside of the vent pipe 9. When there is no liquid nitrogen evaporation, the rubber stopper 12 can be installed inside the vent pipe 9 to prevent the gas from diffusing to the outside. There are four storage bags 15, which are evenly distributed on the outer surface of the storage tank 4. When the inside of the storage bag 15 is full of nitrogen, the opening of the storage bag 15 is sealed with a drawstring 16, and then the nitrogen in the storage bag 15 can be transported to a suitable location to prevent the discharged nitrogen from threatening the operators and the environment.
[0027] The telescopic rod 6 in this application is a common electrical device in the prior art. This application will not elaborate on its model or internal structure. It can also be replaced by other power sources.
[0028] In use, when liquid nitrogen evaporates, the rubber stopper 12 is removed from the inside of the outlet pipe 9, increasing the pressure inside the tank 1. The moving plate 5 moves downward, and the limiting plate 10 slides on the inner wall of the limiting groove 11. The spring 8 is compressed, and the spring 8 drives the telescopic rod 6 to shorten. The moving plate 5 leaves the screw tube 3, opening the gas passage. Gas enters the storage tank 4 and then enters the storage bag 15 through the outlet pipe 9 to store nitrogen. This reduces the pressure inside the tank 1. The gas inside the storage tank 4 flows into the storage bag 15 through the outlet pipe 9. The opening of the storage bag 15 is then sealed with the drawstring 16, and the nitrogen in the storage bag 15 is transported to a suitable location. This prevents the discharged nitrogen from threatening the operators and the environment. When the pressure inside the tank 1 gradually decreases, the spring 8 resets, the telescopic rod 6 shortens, and the moving plate 5 returns to the inside of the screw tube 3, closing the gas release passage.
[0029] The technical principles of this utility model have been described above with reference to specific embodiments. These descriptions are merely for explaining the principles of this utility model and should not be construed as limiting the scope of protection of this utility model in any way. Based on this explanation, those skilled in the art can readily conceive of other specific embodiments of this utility model without inventive effort, and these embodiments will all fall within the protection scope of the claims of this utility model.
Claims
1. A liquid nitrogen transfer container for hematopoietic stem cells, comprising a container body (1), characterized in that: The bottom surface of the tank (1) is fixedly connected to an outlet (2). The outer surface of the outlet (2) is threadedly connected to a spiral tube (3). The outer surface of the spiral tube (3) is fixedly connected to a storage tank (4). The inner wall of the spiral tube (3) is slidably connected to a moving plate (5). The outer surface of the moving plate (5) is connected to a telescopic rod (6). One end of the telescopic rod (6) is connected to a circular plate (7). A spring (8) is sleeved on the outside of the telescopic rod (6). One end of the spring (8) is connected to the bottom surface of the moving plate (5). The other end of the spring (8) is connected to the upper surface of the circular plate (7). The outer surface of the circular plate (7) is connected to the inner wall of the storage tank (4). The outer surface of the storage tank (4) is fixedly connected to an air outlet pipe (9).
2. The hematopoietic stem cell liquid nitrogen transfer container according to claim 1, characterized in that: The outer surface of the movable plate (5) is connected to a limiting plate (10), and the inner wall of the screw tube (3) is provided with a limiting groove (11). The outer surface of the limiting plate (10) is slidably connected to the inner wall of the limiting groove (11).
3. The hematopoietic stem cell liquid nitrogen transfer container according to claim 1, characterized in that: A rubber plug (12) is slidably connected to the inner wall of the air outlet pipe (9), and a pull rod (13) is connected to the outer surface of the rubber plug (12).
4. The hematopoietic stem cell liquid nitrogen transfer container according to claim 1, characterized in that: The upper surface of the circular plate (7) is provided with through holes (14), and the through holes (14) are evenly distributed on the upper surface of the circular plate (7).
5. The hematopoietic stem cell liquid nitrogen transfer container according to claim 1, characterized in that: A storage bag (15) is slidably connected to the outer surface of the air outlet pipe (9), and a drawstring (16) is provided on the outer surface of the storage bag (15).
6. The hematopoietic stem cell liquid nitrogen transfer container according to claim 1, characterized in that: The bottom surface of the tank (1) is connected to a support rod (17), the bottom end of the support rod (17) is connected to a rubber pad (18), and the outer surface of the tank (1) is connected to a bracket (19).
7. A liquid nitrogen transfer container for hematopoietic stem cells according to claim 5, characterized in that: There are four storage bags (15), which are evenly distributed on the outer surface of the storage tank (4).