Ultrafiltration device for purifying sodium hyaluronate
By integrating high-pressure rinsing and mechanical vibration cleaning technologies, the problem of easy clogging of filter membranes during the purification of sodium hyaluronate has been solved, achieving efficient cleaning of filter membranes, extending their service life, and facilitating maintenance.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- QINGDAO HUAYUAN BIOLOGICAL CO LTD
- Filing Date
- 2025-06-05
- Publication Date
- 2026-05-29
Smart Images

Figure CN224292946U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of ultrafiltration device technology, specifically to an ultrafiltration device for purifying sodium hyaluronate. Background Technology
[0002] Sodium hyaluronate is a natural polysaccharide widely found in human connective tissue, skin, eyes, and synovial fluid. Physically, it exhibits excellent optical transparency, maintaining a clear and transparent state in solution; it also displays typical non-Newtonian fluid characteristics, meaning its viscosity changes with shear rate. Chemically, the hydroxyl and carboxyl groups in its molecule give it certain chemical reactivity. Sodium hyaluronate (sodium hyaluronate) is a high-molecular-weight polysaccharide widely used in pharmaceuticals, cosmetics, and medical aesthetics. Its purification process is crucial for controlling product purity and molecular weight.
[0003] In traditional ultrafiltration devices, the high viscosity of sodium hyaluronate solution during purification can easily lead to the formation of a concentration polarization layer on the membrane surface, resulting in a decrease in flux and requiring frequent shutdowns for cleaning. Conventional backwashing or chemical cleaning is insufficient to completely remove residues from the membrane pores, affecting membrane life and purification efficiency. To address this, we propose an ultrafiltration device for sodium hyaluronate purification. Utility Model Content
[0004] The technical problem to be solved by this utility model is to overcome the existing defects and provide an ultrafiltration device for the purification of sodium hyaluronate, which integrates high-pressure rinsing and mechanical vibration dual cleaning technology to effectively prevent filter membrane clogging and extend service life; it adopts a quick disassembly and assembly structure and a stable support design to facilitate filter membrane replacement and maintenance, and can effectively solve the problems in the background art.
[0005] To achieve the above objectives, this utility model provides the following technical solution: an ultrafiltration device for purifying sodium hyaluronate, comprising a base frame and a wastewater pipe;
[0006] Base frame: Supports are fixed at the four corners of the top surface. A cleaning unit is provided on the inner side of the support. A frame is installed inside the cleaning unit. The front and rear sides of the frame are evenly fixed with corresponding mounting seats. A filter membrane is placed inside the mounting seat. The water outlet pipe on the surface of the sewage pipe is connected to the water inlet on the bottom surface of the filter membrane at the corresponding position. A connecting flange is fixed on the left side of the sewage pipe. A clean water pipe is installed on the surface of the filter membrane.
[0007] It also includes a controller, which is located on the surface of the left bracket, and the input terminal of the controller is electrically connected to the output terminal of an external power supply.
[0008] Wastewater enters the filter membrane through the wastewater pipe for filtration, and the filtered clean water is discharged through the clean water pipe.
[0009] Furthermore, the cleaning unit includes a cleaning water pipe, a water distribution pipe, a solenoid valve, a cleaning tank, and a liquid pump. The surface of the cleaning water pipe is evenly provided with water distribution pipes. The bottom end of the water distribution pipe is connected to the top end of the solenoid valve. The bottom end of the solenoid valve is connected to the flushing port at the top of the filter membrane. The top surface of the cleaning tank is equipped with a liquid pump. The outlet pipe of the liquid pump is connected to the inlet of the cleaning water pipe. The input ends of the solenoid valve and the liquid pump are electrically connected to the output end of the controller. The liquid pump is started to backwash the inside of the filter membrane with the cleaning liquid inside the cleaning tank through the water distribution pipe. The solenoid valve can control the flow rate of the cleaning liquid.
[0010] Furthermore, the cleaning unit also includes a vibration motor, springs, sliding columns, and sliding holes. There are four sliding columns, which are fixed in pairs on the inner side of the bracket. The sliding holes are opened on the surface of the frame. The sliding columns and sliding holes are slidably installed. There are two springs, which are respectively sleeved on the two ends of the outer side of the sliding columns. The springs are located between the frame and the bracket. There are two vibration motors, which are respectively fixed on the two ends of the front side of the frame. The input end of the vibration motor is electrically connected to the output end of the controller. The vibration motors make the sliding columns slide inside the sliding holes and, together with the springs, generate lateral shearing force, thereby effectively removing residual sodium hyaluronate and impurities inside the filter membrane and preventing membrane pore blockage.
[0011] Furthermore, the cleaning unit also includes a liquid level sensor, a motor, and a stirring rack. There are two motors, which are fixed on both sides of the top surface of the cleaning tank. The output shaft of the motor is connected to the top of the stirring rack, which is located inside the cleaning tank. The liquid level sensor is installed on the rear side of the cleaning tank. The output of the liquid level sensor is electrically connected to the input of the controller, and the input of the motor is electrically connected to the output of the controller. The motor drives the stirring rack to rotate to mix the cleaning agent with the liquid, preventing the cleaning agent from settling in the cleaning tank and ensuring a uniform concentration of the rinsing solution. At the same time, the liquid level sensor can remind personnel to add liquid when the liquid level is low.
[0012] Furthermore, it also includes fixing bolts, anti-detachment brackets, and supports. The supports are evenly fixed to the bottom surface of the frame, and the top surface of the supports is in contact with the bottom surface of the filter membrane. The anti-detachment brackets are slidably installed on the outside of the mounting base. The screw holes on the surface of the anti-detachment brackets are threaded with the fixing bolts. The anti-detachment brackets are slidably installed on the outside of the mounting base and are fixed and locked with fixing bolts to prevent the filter membrane from shifting during use. The supports can provide support for the bottom surface of the filter membrane to distribute pressure.
[0013] Furthermore, it also includes a flow sensor and a display screen. The flow sensor is installed at the end of the water purification pipe, and the display screen is fixed to the front side of the right bracket. The output end of the flow sensor is electrically connected to the input end of the controller, and the input end of the display screen is electrically connected to the output end of the controller. The flow sensor can detect the flow rate of the liquid, and can automatically clean the filter membrane when the flow rate is low.
[0014] Compared with the prior art, the beneficial effects of this utility model are as follows: This ultrafiltration device for purifying sodium hyaluronate has the following advantages:
[0015] 1. The cleaning solution inside the cleaning tank is backwashed and cleaned through the water distribution pipe by starting the liquid pump. The solenoid valve controls the flow rate of the cleaning solution, while the motor drives the stirring rack to mix the cleaning agent with the liquid, preventing the cleaning agent from settling in the cleaning tank and ensuring that the rinsing solution concentration is uniform. At the same time, the liquid level sensor can remind personnel to add liquid when the liquid level is low.
[0016] 2. The vibration motor is used to make the sliding column slide inside the sliding hole, and the spring generates a lateral shearing force, thereby effectively removing sodium hyaluronate and impurities from the inside of the filter membrane and preventing membrane pore blockage.
[0017] 3. The anti-detachment bracket is slidably installed on the outside of the mounting base and fixed and locked with fixing bolts to prevent the filter membrane from shifting during use. The bracket can provide support for the bottom surface of the filter membrane to distribute pressure. Attached Figure Description
[0018] Figure 1 This is a schematic diagram of the structure of this utility model;
[0019] Figure 2 This is a schematic diagram of the cleaning unit structure of this utility model;
[0020] Figure 3 This is a schematic diagram of the cross-sectional structure of the frame of this utility model.
[0021] In the diagram: 1. Base frame, 2. Cleaning unit, 21. Cleaning water pipe, 22. Distribution pipe, 23. Solenoid valve, 24. Cleaning tank, 25. Liquid pump, 26. Vibration motor, 27. Spring, 28. Sliding column, 29. Sliding hole, 210. Liquid level sensor, 211. Motor, 212. Stirring rack, 3. Bracket, 4. Frame, 5. Mounting base, 6. Filter membrane, 7. Clean water pipe, 8. Connecting flange, 9. Sewage pipe, 10. Fixing bolt, 11. Anti-detachment bracket, 12. Bracket, 13. Flow sensor, 14. Display screen, 15. Controller. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0023] Please see Figure 1-3 This embodiment provides a technical solution: an ultrafiltration device for purifying sodium hyaluronate, including a base frame 1 and a wastewater pipe 9;
[0024] Base frame 1: Support brackets 3 are fixed at all four corners of the top surface. Cleaning units 2 are provided on the inner side of the support brackets 3. A frame 4 is installed inside the cleaning unit 2. Mounting seats 5 are evenly fixed on the front and back sides of the frame 4. Filter membranes 6 are placed inside the mounting seats 5. The water outlet pipes on the surface of the sewage pipe 9 are connected to the water inlets on the bottom surface of the filter membrane 6 at the corresponding positions. A connecting flange 8 is fixed to the left end of the sewage pipe 9. Clean water pipes 7 are installed on the surface of the filter membrane 6. The cleaning unit 2 includes a clean water pipe 21, a water distribution pipe 22, a solenoid valve 23, a cleaning tank 24, and a liquid pump 25. Water distribution pipes 22 are evenly arranged on the surface of the clean water pipe 21. The bottom end of the water distribution pipe 22 is connected to the solenoid valve. The top of the cleaning unit 23 is connected to the filter membrane 6, and the bottom of the solenoid valve 23 is connected to the flushing port at the top of the filter membrane 6. A liquid pump 25 is installed on the top surface of the cleaning tank 24. The outlet pipe of the liquid pump 25 is connected to the inlet of the cleaning water pipe 21. The input terminals of the solenoid valve 23 and the liquid pump 25 are electrically connected to the output terminal of the controller 15. The liquid pump 25 is started to backwash the filter membrane 6 through the water distribution pipe 22 with the cleaning liquid inside the cleaning tank 24. The solenoid valve 23 can control the flow rate of the cleaning liquid. The cleaning unit 2 also includes a vibration motor 26, a spring 27, a sliding column 28, and a sliding hole 29. There are four sliding columns 28, which are fixed in pairs on the inner side of the bracket 3. A movable hole 29 is formed on the surface of the frame 4. The sliding column 28 is slidably installed with the sliding hole 29. There are two springs 27, which are respectively sleeved on both ends of the outer side of the sliding column 28. The springs 27 are located between the frame 4 and the bracket 3. There are two vibration motors 26, which are respectively fixed on both ends of the front side of the frame 4. The input end of the vibration motor 26 is electrically connected to the output end of the controller 15. The vibration motor 26 causes the sliding column 28 to slide inside the sliding hole 29 and, together with the springs 27, generates a lateral shearing force, thereby effectively removing residual sodium hyaluronate and impurities inside the filter membrane 6 and preventing membrane pore blockage. The cleaning unit 2 also includes a liquid level sensor 210, a motor 211, and a stirrer. The cleaning tank 24 has two motors 211, which are fixed on both sides of the top surface of the cleaning tank 24. The output shaft of the motor 211 is connected to the top of the mixing rack 212, which is located inside the cleaning tank 24. The liquid level sensor 210 is installed on the rear side of the cleaning tank 24. The output of the liquid level sensor 210 is electrically connected to the input of the controller 15, and the input of the motor 211 is electrically connected to the output of the controller 15. The motor 211 drives the mixing rack 212 to rotate to mix the cleaning agent and the liquid, preventing the cleaning agent from settling in the cleaning tank 24 and ensuring that the concentration of the rinsing liquid is uniform. At the same time, the liquid level sensor 210 can remind personnel to add liquid when the liquid level is low.
[0025] The system also includes a controller 15, which is mounted on the surface of the left support 3. The input of the controller 15 is electrically connected to the output of an external power supply. Wastewater enters the filter membrane 6 through the wastewater pipe 9 for filtration, and the filtered clean water is discharged through the clean water pipe 7. The system also includes fixing bolts 10, an anti-detachment bracket 11, and a support 12. The support 12 is evenly fixed to the bottom surface of the frame 4, and its top surface is in contact with the bottom surface of the filter membrane 6. The anti-detachment bracket 11 is slidably mounted on the outside of the mounting base 5. The screw holes on the surface of the anti-detachment bracket 11 are threaded onto the fixing bolts 10. The filter membrane 6 is secured and locked using fixing bolts 10 to prevent displacement during use. The bracket 12 provides support for the bottom surface of the filter membrane 6 to distribute pressure. The system also includes a flow sensor 13 and a display screen 14. The flow sensor 13 is installed at the end of the water purification pipe 7, and the display screen 14 is fixed to the front side of the right bracket 3. The output of the flow sensor 13 is electrically connected to the input of the controller 15, and the input of the display screen 14 is electrically connected to the output of the controller 15. The flow sensor 13 can detect the flow rate of the liquid and automatically clean the filter membrane 6 when the flow rate is low.
[0026] The working principle of the ultrafiltration device for sodium hyaluronate purification provided by this utility model is as follows: First, the filter membrane 6 is placed inside the mounting base 6. The anti-detachment bracket 11 is slidably installed on the outside of the mounting base 5 and fixed and locked with fixing bolts 10 to prevent the filter membrane 6 from shifting during use. The bracket 12 can provide support for the bottom surface of the filter membrane 6 to distribute pressure. Then, the flow sensor 13 can detect the flow rate of the liquid. When the flow rate is low, the liquid pump 25 can be automatically started to pump the cleaning liquid inside the cleaning tank 24 through the water distribution pipe 22 to the filter membrane. The interior of filter membrane 6 is backwashed and cleaned. The solenoid valve 23 controls the flow rate of the cleaning fluid, while the motor 211 drives the stirring rack 212 to rotate and mix the cleaning agent with the liquid, preventing the cleaning agent from settling in the cleaning tank 24 and ensuring that the concentration of the rinsing fluid is uniform. At the same time, the liquid level sensor 210 can remind personnel to add liquid when the liquid level is low. Meanwhile, the vibration motor 26 makes the sliding column 28 slide inside the sliding hole 29, and with the help of the spring 27, it generates a lateral shearing force, thereby effectively removing residual sodium hyaluronate and impurities inside the filter membrane 6 and preventing the membrane pores from clogging.
[0027] It is worth noting that the controller 15 disclosed in the above embodiments is model S7-1214C, while the vibration motor 26 can be freely configured according to the actual application scenario. It is recommended to use a vibration motor of model MVE-500 / 3. The liquid pump 25 can be a liquid pump of model CM1-3, and the flow sensor 13 can be a flow sensor of model SITRANS-FM-MAG-3100. The controller 15 controls the operation of the solenoid valve 23, liquid pump 25, vibration motor 26, liquid level sensor 210, motor 211, flow sensor 13, and display screen 14 using methods commonly used in the prior art.
[0028] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the content of this utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.
Claims
1. An ultrafiltration device for purifying sodium hyaluronate, characterized in that: Includes the base frame (1) and the sewage pipe (9); Base frame (1): Supports (3) are fixed at the four corners of the top surface. A cleaning unit (2) is provided on the inner side of the support (3). A frame (4) is installed inside the cleaning unit (2). The front and rear sides of the frame (4) are evenly fixed with corresponding mounting seats (5). A filter membrane (6) is placed inside the mounting seat (5). The water outlet pipe on the surface of the sewage pipe (9) is connected to the water inlet on the bottom surface of the filter membrane (6) at the corresponding position. A connecting flange (8) is fixed on the left side end of the sewage pipe (9). A clean water pipe (7) is installed on the surface of the filter membrane (6). It also includes a controller (15), which is located on the surface of the left bracket (3), and the input end of the controller (15) is electrically connected to the output end of an external power supply.
2. The ultrafiltration device for purifying sodium hyaluronate according to claim 1, characterized in that: The cleaning unit (2) includes a cleaning water pipe (21), a water distribution pipe (22), a solenoid valve (23), a cleaning tank (24), and a liquid pump (25). The surface of the cleaning water pipe (21) is uniformly provided with water distribution pipes (22). The bottom end of the water distribution pipe (22) is connected to the top end of the solenoid valve (23). The bottom end of the solenoid valve (23) is connected to the flushing port at the top of the filter membrane (6). The top surface of the cleaning tank (24) is equipped with a liquid pump (25). The outlet pipe of the liquid pump (25) is connected to the inlet of the cleaning water pipe (21). The input ends of the solenoid valve (23) and the liquid pump (25) are electrically connected to the output end of the controller (15).
3. The ultrafiltration device for purifying sodium hyaluronate according to claim 1, characterized in that: The cleaning unit (2) also includes a vibration motor (26), a spring (27), a sliding column (28), and a sliding hole (29). There are four sliding columns (28) and they are fixed in pairs on the inner side of the bracket (3). The sliding hole (29) is opened on the surface of the frame (4). The sliding column (28) and the sliding hole (29) are slidably installed. There are two springs (27) and they are respectively sleeved on the two ends of the outer side of the sliding column (28). The springs (27) are located between the frame (4) and the bracket (3). There are two vibration motors (26) and they are respectively fixed on the two ends of the front side of the frame (4). The input end of the vibration motor (26) is electrically connected to the output end of the controller (15).
4. The ultrafiltration device for purifying sodium hyaluronate according to claim 2, characterized in that: The cleaning unit (2) also includes a liquid level sensor (210), a motor (211) and a stirring rack (212). There are two motors (211) and they are fixed on both sides of the top surface of the cleaning tank (24). The output shaft of the motor (211) is connected to the top of the stirring rack (212). The stirring rack (212) is located inside the cleaning tank (24). The liquid level sensor (210) is installed on the rear side of the cleaning tank (24). The output end of the liquid level sensor (210) is electrically connected to the input end of the controller (15). The input end of the motor (211) is electrically connected to the output end of the controller (15).
5. The ultrafiltration device for purifying sodium hyaluronate according to claim 1, characterized in that: It also includes fixing bolts (10), anti-detachment brackets (11) and brackets (12). The brackets (12) are evenly fixed on the bottom surface of the frame (4). The top surface of the brackets (12) is in contact with the bottom surface of the filter membrane (6). The anti-detachment brackets (11) are slidably installed on the outside of the mounting base (5). The screw holes on the surface of the anti-detachment brackets (11) are threadedly installed with the fixing bolts (10).
6. The ultrafiltration device for purifying sodium hyaluronate according to claim 1, characterized in that: It also includes a flow sensor (13) and a display screen (14). The flow sensor (13) is installed at the end of the water purification pipe (7), and the display screen (14) is fixed on the front side of the right bracket (3). The output end of the flow sensor (13) is electrically connected to the input end of the controller (15), and the input end of the display screen (14) is electrically connected to the output end of the controller (15).