A mixing device based on mycobacterium tuberculosis drug sensitivity detection
By designing a mixing device for drug susceptibility testing of Mycobacterium tuberculosis, which utilizes motor-driven rotation and automatic clamping adjustment of spring tube clamps, the problems of long testing cycles and cumbersome manual operation in existing technologies are solved, achieving efficient mixing and automated testing.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- TB HEALTHCARE BIOTECHNOLOGY (GUANGDONG) CO LTD
- Filing Date
- 2025-06-09
- Publication Date
- 2026-05-29
AI Technical Summary
Existing methods for detecting tuberculosis drug susceptibility are time-consuming and involve cumbersome manual operations, resulting in low detection efficiency and large errors, which affect treatment outcomes.
A mixing device based on tuberculosis drug susceptibility detection was designed. The device uses a motor to drive the placement disk to rotate, generating centrifugal force and eddy current effect to accelerate the mixing of the sample and diluent. The clamping force is automatically adjusted by a spring tube clamp to reduce manual intervention.
It achieves efficient mixing of samples and diluents, shortens the detection cycle, reduces manual operation, and improves detection accuracy and automation.
Smart Images

Figure CN224293057U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical testing equipment technology, specifically a mixing device based on Mycobacterium tuberculosis drug sensitivity detection. Background Technology
[0002] Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which seriously threatens human health. In the treatment of tuberculosis, it is crucial to accurately detect the sensitivity of Mycobacterium tuberculosis to various anti-tuberculosis drugs, as this directly affects the formulation of treatment plans and treatment outcomes.
[0003] Currently, traditional drug sensitivity testing methods, such as culture methods (solid / liquid), require long cycles and need to be combined with phenotypic drug sensitivity tests. This process is time-consuming, involves a lot of manual intervention, is cumbersome, and heavily relies on professionals. This not only delays the optimal treatment time for patients but may also introduce uncontrollable factors due to manual operation during the culture process, potentially leading to worsening of the condition and increased detection errors. This puts great pressure on the high accuracy requirements of clinical testing. Utility Model Content
[0004] (a) Technical problems to be solved
[0005] To address the shortcomings of existing technologies, this invention provides a mixing device for Mycobacterium tuberculosis drug susceptibility testing. This device has the advantages of accelerating the efficient mixing of samples and diluents, reducing the testing cycle for Mycobacterium tuberculosis drug susceptibility, and achieving full automation by connecting to automated equipment, thereby reducing manual operation. It effectively solves the problems mentioned in the background technology.
[0006] (II) Technical Solution
[0007] To achieve the above objectives, this utility model provides the following technical solution: a mixing device based on tuberculosis drug sensitivity detection, comprising a storage tank, a sealing mechanism above the storage tank, a storage mechanism inside the storage tank, the storage mechanism comprising a motor, the bottom of the motor being fixedly installed in the middle of the bottom inside the storage tank, a rotating shaft being fixedly connected to the top of the motor, a placement tray being fixedly connected to the top of the rotating shaft, and a plurality of placement cylinders being fixedly connected to the upper surface of the placement tray.
[0008] Preferably, a number of spring tubes are fixedly connected to the inner wall of the placement cylinder.
[0009] Preferably, a clamp is fixedly connected to the other end of the spring tube.
[0010] A number of spring tubes are evenly and vertically connected at one end to the inner wall of the placement cylinder. The clamping plate can move elastically through the spring tubes to hold the sample.
[0011] Preferably, the sealing mechanism includes a threaded groove formed on the upper surface of the storage tank.
[0012] Preferably, a threaded tube is provided above the threaded groove.
[0013] Preferably, a sealing cap is fixedly connected to the upper surface of the threaded tube, and a knob is fixedly connected to the middle of the upper surface of the sealing cap.
[0014] The threaded groove fits into the upper surface of the storage tank, and the threaded tube can be screwed into the inside of the threaded groove. The sealing cap can be threadedly connected to the storage tank through the threaded tube at the bottom, making it convenient for operators to disassemble and assemble. The knob makes it easy for operators to turn the sealing cap.
[0015] Compared with the prior art, this utility model provides a mixing device based on Mycobacterium tuberculosis drug susceptibility detection, which has the following beneficial effects:
[0016] This invention utilizes a motor installed at the bottom of the storage tank. The motor drives the placement tray to rotate via a top shaft, and the bottom motor shaft drives the placement tray to rotate. The stable mechanical power output enables efficient mixing of the sample and diluent as they rotate. The centrifugal force and eddy current effect generated during rotation promote liquid stratification and accelerate uniform mixing, greatly reducing sample mixing time and thus shortening the cycle of tuberculosis drug sensitivity testing.
[0017] This invention utilizes a spring tube connected to the inner wall of a placement cylinder. The clamping plate can move elastically through the spring tube, and the clamping plate is displaced by the compression or stretching of the spring tube, automatically adjusting the clamping force to ensure that the sample is fixed. Furthermore, the elastic properties of the spring tube can match the differences in sample size, allowing for the replacement of different samples without changing the container or adjusting the structure, thus reducing manual intervention. Attached Figure Description
[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0019] Figure 2 This is a schematic diagram of the structure of the present invention from a front sectional view.
[0020] Figure 3 This is a schematic diagram of the internal structure of the storage bucket of this utility model;
[0021] Figure 4 This is a top view of the storage mechanism of this utility model.
[0022] The components are: 1. Storage bucket; 2. Sealing mechanism; 201. Threaded groove; 202. Threaded tube; 203. Sealing cover; 204. Knob; 3. Storage mechanism; 301. Motor; 302. Shaft; 303. Placement tray; 304. Placement cylinder; 305. Bourdon tube; 306. Clamping plate. Detailed Implementation
[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0024] Please see Figure 1-4 A mixing device based on Mycobacterium tuberculosis drug susceptibility testing includes a storage tank 1, a sealing mechanism 2 above the storage tank 1, and a storage mechanism 3 inside the storage tank 1. The storage mechanism 3 includes a motor 301, the bottom of which is fixedly installed in the middle of the bottom of the storage tank 1. A rotating shaft 302 is fixedly connected to the top of the motor 301, and a placement tray 303 is fixedly connected to the top of the rotating shaft 302. A number of placement cylinders 304 are fixedly connected to the upper surface of the placement tray 303. The rotating shaft 302 connects the motor 301 and the placement tray 303. The motor 301 can drive the placement tray 303 to rotate through the rotating shaft 302 at the bottom. The bottoms of the number of placement cylinders 304 are evenly and vertically connected to the upper surface of the placement tray 303. Their interiors are used to stabilize the sample, thereby driving the sample to rotate and uniformly and efficiently mix the sample and diluent.
[0025] Specifically, such as Figure 3 and Figure 4 As shown, a number of spring tubes 305 are fixedly connected to the inner wall of the placement cylinder 304, and a clamping plate 306 is fixedly connected to the other end of the spring tube 305.
[0026] Through the above technical solution, a number of spring tubes 305 are uniformly and vertically connected at one end to the inner wall of the placement cylinder 304, and the clamping plate 306 can move elastically through the spring tubes 305 to clamp the sample.
[0027] Specifically, such as Figure 2 As shown, the sealing mechanism 2 includes a threaded groove 201, which is formed on the upper surface of the storage tank 1. A threaded tube 202 is provided above the threaded groove 201. A sealing cover 203 is fixedly connected to the upper surface of the threaded tube 202. A knob 204 is fixedly connected to the middle of the upper surface of the sealing cover 203.
[0028] Through the above technical solution, the threaded groove 201 is fitted into the upper surface of the storage tank 1, the threaded tube 202 can be screwed into the inside of the threaded groove 201, and the sealing cover 203 can be threadedly connected to the storage tank 1 through the threaded tube 202 at the bottom, which is convenient for operators to disassemble and assemble. The knob 204 makes it convenient for operators to rotate the sealing cover 203.
[0029] During use, the operator inserts the prepared sample into the placement tube 304 inside the storage tank 1. The clamp 306 will elastically squeeze the sample according to its specifications, confining it inside the placement tube 304. Then, the threaded tube 202 at the bottom of the sealing cap 203 is screwed into the threaded groove 201 on the upper surface of the storage tank 1 to seal it. The motor 301 at the bottom of the storage tank 1 drives the placement tube 304 to rotate through the top rotating shaft 302, so as to evenly mix the sample and diluent inside.
[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A mixing device based on Mycobacterium tuberculosis drug susceptibility detection, comprising a storage container (1), characterized in that: A sealing mechanism (2) is provided above the storage barrel (1), and a storage mechanism (3) is provided inside the storage barrel (1). The storage mechanism (3) includes a motor (301). The bottom of the motor (301) is fixedly installed in the middle of the bottom of the storage barrel (1). A rotating shaft (302) is fixedly connected to the top of the motor (301). A placement tray (303) is fixedly connected to the top of the rotating shaft (302). A number of placement cylinders (304) are fixedly connected to the upper surface of the placement tray (303).
2. The mixing device based on Mycobacterium tuberculosis drug susceptibility detection according to claim 1, characterized in that: A number of spring tubes (305) are fixedly connected to the inner wall of the placement cylinder (304).
3. The mixing device based on Mycobacterium tuberculosis drug susceptibility detection according to claim 2, characterized in that: The other end of the spring tube (305) is fixedly connected to a clamp (306).
4. The mixing device based on Mycobacterium tuberculosis drug susceptibility detection according to claim 1, characterized in that: The sealing mechanism (2) includes a threaded groove (201) which is formed on the upper surface of the storage tank (1).
5. A mixing device based on Mycobacterium tuberculosis drug susceptibility detection according to claim 4, characterized in that: A threaded tube (202) is provided above the threaded groove (201).
6. A mixing device based on Mycobacterium tuberculosis drug susceptibility detection according to claim 5, characterized in that: A sealing cap (203) is fixedly connected to the upper surface of the threaded tube (202), and a knob (204) is fixedly connected to the middle of the upper surface of the sealing cap (203).